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PE20399A1 - MUTEINA OB - Google Patents

MUTEINA OB

Info

Publication number
PE20399A1
PE20399A1 PE00108697A PE00108697A PE20399A1 PE 20399 A1 PE20399 A1 PE 20399A1 PE 00108697 A PE00108697 A PE 00108697A PE 00108697 A PE00108697 A PE 00108697A PE 20399 A1 PE20399 A1 PE 20399A1
Authority
PE
Peru
Prior art keywords
muteina
muteins
making
methods
relates
Prior art date
Application number
PE00108697A
Other languages
Spanish (es)
Inventor
Yves Guisez
Rene Devos
Geert Plaetinck
Der Heyden Jose Van
Sandra Verploegen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PE20399A1 publication Critical patent/PE20399A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to ob muteins, to DNA sequences coding for these ob muteins and methods for making these.
PE00108697A 1996-12-06 1997-12-02 MUTEINA OB PE20399A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96119606 1996-12-06

Publications (1)

Publication Number Publication Date
PE20399A1 true PE20399A1 (en) 1999-03-05

Family

ID=8223476

Family Applications (1)

Application Number Title Priority Date Filing Date
PE00108697A PE20399A1 (en) 1996-12-06 1997-12-02 MUTEINA OB

Country Status (8)

Country Link
AR (1) AR010333A1 (en)
AU (1) AU5654998A (en)
CO (1) CO4930295A1 (en)
HR (1) HRP970654A2 (en)
MA (1) MA24411A1 (en)
PE (1) PE20399A1 (en)
WO (1) WO1998024896A2 (en)
ZA (1) ZA9710832B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777388B1 (en) 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
US7208572B2 (en) 1998-08-21 2007-04-24 Albany Medical College Leptin-related peptides
US6420339B1 (en) * 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
US8227408B2 (en) 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
CA2725143A1 (en) 2008-05-21 2009-11-26 Neurotez, Inc. Methods for treating progressive cognitive disorders related to neurofibrillary tangles
CN102300581B (en) 2008-11-04 2016-12-21 尼古拉斯·泰萨普塞蒂斯 Leptin compositions and methods for treating progressive cognitive dysfunction due to neurofibrillary tangles and accumulation of beta amyloid
EP2621515B1 (en) 2010-09-28 2017-03-29 Aegerion Pharmaceuticals, Inc. A chimeric seal-human leptin polypeptide with increased solubility

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1259923A (en) * 1983-08-17 1989-09-26 Roger Aston Physiologically active compositions
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
YU5396A (en) * 1995-01-31 1998-08-14 Eli Lilly And Company, Lilly Corporate Center NEW BIOLOGICAL ACTIVE PROTEINS, THEIR PHARMACEUTICAL FORMULATIONS AND THE PROCEDURE FOR THEIR DETERMINATION
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
CO4930295A1 (en) 2000-06-27
HRP970654A2 (en) 1998-10-31
MA24411A1 (en) 1998-07-01
WO1998024896A2 (en) 1998-06-11
ZA9710832B (en) 1998-06-08
AU5654998A (en) 1998-06-29
AR010333A1 (en) 2000-06-07
WO1998024896A3 (en) 1998-10-01

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal