PE20191536A1 - Formulaciones lubricantes - Google Patents
Formulaciones lubricantesInfo
- Publication number
- PE20191536A1 PE20191536A1 PE2019001966A PE2019001966A PE20191536A1 PE 20191536 A1 PE20191536 A1 PE 20191536A1 PE 2019001966 A PE2019001966 A PE 2019001966A PE 2019001966 A PE2019001966 A PE 2019001966A PE 20191536 A1 PE20191536 A1 PE 20191536A1
- Authority
- PE
- Peru
- Prior art keywords
- agent selected
- amount
- mixtures
- vaginal
- buffer
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 230000001050 lubricating effect Effects 0.000 title 1
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000000314 lubricant Substances 0.000 abstract 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- OWPUOLBODXJOKH-UHFFFAOYSA-N 2,3-dihydroxypropyl prop-2-enoate Chemical compound OCC(O)COC(=O)C=C OWPUOLBODXJOKH-UHFFFAOYSA-N 0.000 abstract 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 abstract 1
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 abstract 1
- 229920002126 Acrylic acid copolymer Polymers 0.000 abstract 1
- 229920000084 Gum arabic Polymers 0.000 abstract 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
- DYUQAZSOFZSPHD-UHFFFAOYSA-N Phenylpropanol Chemical compound CCC(O)C1=CC=CC=C1 DYUQAZSOFZSPHD-UHFFFAOYSA-N 0.000 abstract 1
- 206010047791 Vulvovaginal dryness Diseases 0.000 abstract 1
- 235000010489 acacia gum Nutrition 0.000 abstract 1
- 239000000205 acacia gum Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 abstract 1
- 229960005323 phenoxyethanol Drugs 0.000 abstract 1
- 229950009195 phenylpropanol Drugs 0.000 abstract 1
- 239000007981 phosphate-citrate buffer Substances 0.000 abstract 1
- 239000008057 potassium phosphate buffer Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 235000010268 sodium methyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- PESXGULMKCKJCC-UHFFFAOYSA-M sodium;4-methoxycarbonylphenolate Chemical compound [Na+].COC(=O)C1=CC=C([O-])C=C1 PESXGULMKCKJCC-UHFFFAOYSA-M 0.000 abstract 1
- IXMINYBUNCWGER-UHFFFAOYSA-M sodium;4-propoxycarbonylphenolate Chemical compound [Na+].CCCOC(=O)C1=CC=C([O-])C=C1 IXMINYBUNCWGER-UHFFFAOYSA-M 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000035899 viability Effects 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
- 239000000230 xanthan gum Substances 0.000 abstract 1
- 235000010493 xanthan gum Nutrition 0.000 abstract 1
- 229920001285 xanthan gum Polymers 0.000 abstract 1
- 229940082509 xanthan gum Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Lubricants (AREA)
Abstract
Referida a una composicion lubricante vaginal, que comprende: un agente humectante seleccionado entre glicerina en una cantidad entre 1% a 2% p/p, y propanodiol; un agente lubricante seleccionado entre copolimero de gliceril acrilato/acido acrilico en una cantidad entre 0,005% y 0,007% p/p, y copolimero de metilvinileter/anhidrido maleico en una cantidad entre 0,0025% y 0,0035% p/p, y sus mezclas; un agente viscosizante seleccionado entre hidroxietilcelulosa de distintos grados de viscosidad, goma xantana, goma acacia y sus mezclas; un agente conservante seleccionado de fenoxietanol en una cantidad entre 0,45% y 1% p/p, metilparaben sodico, propilparaben sodico y sus mezclas; un potenciador del conservante seleccionado de etilhexilglicerol, fenetilalcohol, fenilpropanol y caprililglicol; un agente regulador del pH seleccionado entre tampon fosfato potasio, tampon citrato y tampon lactico. Dicha composicion no altera la flora vaginal normal, no irrita la mucosa vaginal, es compatible con preservativos y mantiene la viabilidad espermatica; siendo util para el alivio de los sintomas asociados a la sequedad vaginal
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201700388A ES2685002B1 (es) | 2017-03-31 | 2017-03-31 | Formulaciones lubricantes |
| PCT/ES2018/070266 WO2018178478A2 (es) | 2017-03-31 | 2018-03-28 | Formulaciones lubricantes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20191536A1 true PE20191536A1 (es) | 2019-10-23 |
Family
ID=46880800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2019001966A PE20191536A1 (es) | 2017-03-31 | 2018-03-28 | Formulaciones lubricantes |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3603627A4 (es) |
| CN (1) | CN110709070A (es) |
| ES (1) | ES2685002B1 (es) |
| PE (1) | PE20191536A1 (es) |
| WO (1) | WO2018178478A2 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230002923A (ko) | 2020-04-28 | 2023-01-05 | 펩토닉 메디칼 에이비 | 전정통을 치료 및/또는 예방하기 위한 조성물 |
| GB2631253A (en) * | 2023-06-21 | 2025-01-01 | Reckitt Benckiser Health Ltd | Vaginal lubricant |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9015910D0 (en) * | 1990-07-19 | 1990-09-05 | Univ Bruxelles | Novel use |
| ITMI20030195A1 (it) * | 2003-02-06 | 2004-08-07 | Bsd Bioscience Dev Snc Di O Mini C E Zucc | Formulazioni topiche contenenti principi attivi naturali adatte alla prevenzione e cura dei processi infiammatori delle mucose |
| US20100233295A1 (en) * | 2005-03-02 | 2010-09-16 | Vibha Gupta | Aqueous moisturizers and lubricants and uses thereof |
| US7820152B2 (en) * | 2005-05-13 | 2010-10-26 | The Gillette Company | Shave gel composition containing glyceryl acrylate/acrylic acid copolymer |
| GB2431874A (en) * | 2005-11-03 | 2007-05-09 | Cst Medical Ltd | Lubricant |
| KR20090094245A (ko) * | 2006-10-10 | 2009-09-04 | 래크리드 인코포레이티드 | 퍼옥사이드-생성 효소 및 퍼옥시다아제를 사용하여 질 질환을 치료하기 위한 방법 및 조성물 |
| US20090004294A1 (en) * | 2006-11-07 | 2009-01-01 | Pharmwest, Inc. | Personal lubricant formulations comprising colloidal metals and methods of use |
| GB2451503B (en) * | 2007-08-01 | 2011-10-12 | Lrc Products | Stimulating gel comprising a cyclic carboxamide coolant |
| CN105362160B (zh) * | 2015-12-16 | 2019-01-11 | 广州市中通生化制品有限公司 | 一种含中草药提取物的泥面膜及其制备方法 |
| CN106109316A (zh) * | 2016-07-26 | 2016-11-16 | 广州众上投资控股集团有限公司 | 一种含薏仁提取物、枳实提取物和娑罗子提取物的极氧活颜水及其制备方法 |
-
2017
- 2017-03-31 ES ES201700388A patent/ES2685002B1/es active Active
-
2018
- 2018-03-28 EP EP18776381.8A patent/EP3603627A4/en not_active Withdrawn
- 2018-03-28 CN CN201880023941.3A patent/CN110709070A/zh active Pending
- 2018-03-28 PE PE2019001966A patent/PE20191536A1/es unknown
- 2018-03-28 WO PCT/ES2018/070266 patent/WO2018178478A2/es not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3603627A2 (en) | 2020-02-05 |
| WO2018178478A2 (es) | 2018-10-04 |
| EP3603627A4 (en) | 2021-01-06 |
| WO2018178478A3 (es) | 2018-11-22 |
| ES2685002B1 (es) | 2019-07-17 |
| ES2685002A1 (es) | 2018-10-05 |
| CN110709070A (zh) | 2020-01-17 |
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