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PE20110544A1 - Formulacion farmaceutica de liberacion controlada que comprende isomero r de lansoprazol - Google Patents

Formulacion farmaceutica de liberacion controlada que comprende isomero r de lansoprazol

Info

Publication number
PE20110544A1
PE20110544A1 PE2011001026A PE2011001026A PE20110544A1 PE 20110544 A1 PE20110544 A1 PE 20110544A1 PE 2011001026 A PE2011001026 A PE 2011001026A PE 2011001026 A PE2011001026 A PE 2011001026A PE 20110544 A1 PE20110544 A1 PE 20110544A1
Authority
PE
Peru
Prior art keywords
controlled
isomer
granule
coating
pharmaceutical formulation
Prior art date
Application number
PE2011001026A
Other languages
English (en)
Inventor
Yohko Akiyama
Takashi Kurasawa
Hiroto Bando
Naoki Nagahara
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32109465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20110544(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of PE20110544A1 publication Critical patent/PE20110544A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA TABLETA, GRANULO O GRANULO FINO CON LIBERACION CONTROLADA DEL INGREDIENTE ACTIVO QUE COMPRENDE: A) UNA PARTICULA CENTRAL QUE CONTIENE LANSOPRAZOL O UN ISOMERO DEL MISMO; B) UNA CAPA DE RECUBRIMIENTO DE LIBERACION CONTROLADA SOLUBLE DEPENDIENTE DEL PH QUE COMPRENDE DOS O MAS SUSTANCIAS POLIMERICAS QUE SE DISUELVEN A UN RANGO DE pH DE 6.0 A 7.5, LOS CUALES SON HIDROXIPROPILMETIL CELULOSA FTALATO, ACETATO DE CELULOSA FTALATO, CARBOXIMETILETILCELULOSA, POLIVINIL ACETATO FTALATO, ENTRE OTROS. DICHO GRANULO O GRANULO FINO POSEE UN TAMANO DE PARTICULA ENTRE 100 Y 1500 um Y COMPRENDE UN RECUBRIMIENTO ENTERICO EN LA PARTICULA CENTRAL QUE CONTIENE EL PRINCIPIO ACTIVO, UNA CAPA DE DESINTEGRACION EN DICHO RECUBRIMIENTO ENTERICO Y UNA CAPA DE RECUBRIMIENTO DE LIBERACION CONTROLADA EN DICHA CAPA DE DESINTEGRACION, SIENDO LA CANTIDAD DE MATERIAL DE RECUBRIMIENTO DE 20 A 100% BASADA EN LA PARTICULA CENTRAL
PE2011001026A 2002-10-16 2003-10-10 Formulacion farmaceutica de liberacion controlada que comprende isomero r de lansoprazol PE20110544A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002301876 2002-10-16
JP2003066336 2003-03-12

Publications (1)

Publication Number Publication Date
PE20110544A1 true PE20110544A1 (es) 2011-08-25

Family

ID=32109465

Family Applications (3)

Application Number Title Priority Date Filing Date
PE2011001026A PE20110544A1 (es) 2002-10-16 2003-10-10 Formulacion farmaceutica de liberacion controlada que comprende isomero r de lansoprazol
PE2008001635A PE20090076A1 (es) 2002-10-16 2003-10-10 Preparacion de liberacion controlada
PE2003001034A PE20050102A1 (es) 2002-10-16 2003-10-10 Preparacion de liberacion controlada

Family Applications After (2)

Application Number Title Priority Date Filing Date
PE2008001635A PE20090076A1 (es) 2002-10-16 2003-10-10 Preparacion de liberacion controlada
PE2003001034A PE20050102A1 (es) 2002-10-16 2003-10-10 Preparacion de liberacion controlada

Country Status (27)

Country Link
US (7) US7790755B2 (es)
EP (3) EP2277510B1 (es)
JP (2) JP5330967B2 (es)
KR (3) KR101401913B1 (es)
CN (1) CN101884629B (es)
AR (1) AR041562A1 (es)
AU (2) AU2003272098B2 (es)
BR (2) BRPI0315142B8 (es)
CA (2) CA2737851C (es)
CR (2) CR10284A (es)
CY (1) CY1114599T1 (es)
DK (1) DK1553929T3 (es)
ES (1) ES2410812T5 (es)
IL (1) IL167447A (es)
MA (1) MA27456A1 (es)
MX (2) MXPA05003902A (es)
MY (2) MY148805A (es)
NO (2) NO342002B1 (es)
NZ (2) NZ539353A (es)
OA (1) OA13143A (es)
PE (3) PE20110544A1 (es)
PL (2) PL219122B1 (es)
PT (1) PT1553929E (es)
SG (1) SG164281A1 (es)
SI (1) SI1553929T1 (es)
TW (2) TWI347202B (es)
WO (1) WO2004035020A2 (es)

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