PE20091392A1 - Composiciones farmaceuticas como agentes antiinflamatorios - Google Patents
Composiciones farmaceuticas como agentes antiinflamatoriosInfo
- Publication number
- PE20091392A1 PE20091392A1 PE2008001774A PE2008001774A PE20091392A1 PE 20091392 A1 PE20091392 A1 PE 20091392A1 PE 2008001774 A PE2008001774 A PE 2008001774A PE 2008001774 A PE2008001774 A PE 2008001774A PE 20091392 A1 PE20091392 A1 PE 20091392A1
- Authority
- PE
- Peru
- Prior art keywords
- cyclopentil
- purin
- pyrrolidin
- ethylamine
- pyridin
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- RXMTUVIKZRXSSM-UHFFFAOYSA-N 2,2-diphenylethanamine Chemical compound C=1C=CC=CC=1C(CN)C1=CC=CC=C1 RXMTUVIKZRXSSM-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000004702 methyl esters Chemical class 0.000 abstract 2
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 102000014974 beta2-adrenergic receptor activity proteins Human genes 0.000 abstract 1
- 108040006828 beta2-adrenergic receptor activity proteins Proteins 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000003149 muscarinic antagonist Substances 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
REFERIDO A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) UN COMPUESTO SELECCIONADO DE METIL ESTER DE ACIDO ((1S,2R,3S,4R)-4-{6-(2,2-DIFENIL-ETILAMINO)-2-[(S)-3-(3-PIRIDIN-3-IL-UREIDO)-PIRROLIDIN-1-IL]-PURIN-9-IL}-2,3-DIHIDROXI-CICLOPENTIL)-CARBAMICO; METIL ESTER DE ACIDO ((1S, 2R, 3S, 4R)-4-{6-(2,2-DIFENIL-ETILAMINO)-2-[(R)-3-(3-PIRIDIN-3-IL-UREIDO)-PIRROLIDIN-1-IL}-PURIN-9-IL]-2,3-DIHIDROXI-CICLOPENTIL)-CARBAMICO; ((1S,2R,3S,4R)-4-{6-(2,2-DIFENIL-ETILAMINO)-2-[(R)-3-(3-PIRIDIN-3-IL-UREIDO)PIRROLIDIN-1-IL]-PURIN-9-IL}-2,3-DIHIDROXI-CICLOPENTIL)-AMIDA; ENTRE OTROS Y B) UNO O MAS COMPUESTOS SELECCIONADOS DE i) UN CORTICOSTEROIDE, ii) UN ANTAGONISTA DE BETA-2 ADRENOCEPTOR, iii) UN AGENTE ANTIMUSCARINICO, iv) UN ANTAGONISTA DE A2B, v) UNA ANTIHISTAMINA, ENTRE OTROS. TAMBIEN SE REFIERE A UN KIT QUE COMPRENDE UNA COMPOSICION FARMACEUTICA Y UN DISPOSITIVO DE INHALACION. SIENDO UTILES EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS U OBSTRUCTIVAS DE LAS VIAS RESPIRATORIAS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07118721 | 2007-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20091392A1 true PE20091392A1 (es) | 2009-10-14 |
Family
ID=39185790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2008001774A PE20091392A1 (es) | 2007-10-17 | 2008-10-15 | Composiciones farmaceuticas como agentes antiinflamatorios |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20090181934A1 (es) |
| EP (1) | EP2211865A2 (es) |
| JP (1) | JP2011500630A (es) |
| KR (1) | KR20100075925A (es) |
| CN (1) | CN101827596A (es) |
| AR (1) | AR068879A1 (es) |
| AU (1) | AU2008313788A1 (es) |
| BR (1) | BRPI0818005A2 (es) |
| CA (1) | CA2702942A1 (es) |
| CL (1) | CL2008003057A1 (es) |
| CR (1) | CR11341A (es) |
| CU (1) | CU20100065A7 (es) |
| EA (1) | EA201000617A1 (es) |
| IL (1) | IL204723A0 (es) |
| MA (1) | MA31796B1 (es) |
| MX (1) | MX2010004252A (es) |
| PE (1) | PE20091392A1 (es) |
| TN (1) | TN2010000168A1 (es) |
| TW (1) | TW200927129A (es) |
| WO (1) | WO2009050198A2 (es) |
| ZA (1) | ZA201002336B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200500281A (es) * | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| GB0500785D0 (en) | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
| GB0607950D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| GB0607948D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| KR20080110925A (ko) * | 2006-04-21 | 2008-12-19 | 노파르티스 아게 | 아데노신 ａ２ａ 수용체 효능제로서 사용하기 위한 퓨린 유도체 |
| GB0607945D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| GB0607953D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| GB0607944D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| EP1889846A1 (en) | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
| EP1903044A1 (en) * | 2006-09-14 | 2008-03-26 | Novartis AG | Adenosine Derivatives as A2A Receptor Agonists |
| RU2009121819A (ru) * | 2006-11-10 | 2010-12-20 | Новартис АГ (CH) | Производные моноацетата циклопентендиола |
| CA2703039A1 (en) * | 2007-10-17 | 2009-04-23 | Novartis Ag | Purine derivatives as adenosine a1 receptor ligands |
| ES2627541T3 (es) | 2012-04-20 | 2017-07-28 | Ucb Pharma, S.A. | Métodos para tratar la enfermedad de Parkinson |
| JP7625524B2 (ja) | 2019-01-11 | 2025-02-03 | オメロス コーポレーション | がんを処置するための方法および組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200500281A (es) * | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| GB0607950D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| KR20080110925A (ko) * | 2006-04-21 | 2008-12-19 | 노파르티스 아게 | 아데노신 ａ２ａ 수용체 효능제로서 사용하기 위한 퓨린 유도체 |
| GB0607945D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| GB0607953D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
-
2008
- 2008-10-08 US US12/247,764 patent/US20090181934A1/en not_active Abandoned
- 2008-10-15 WO PCT/EP2008/063869 patent/WO2009050198A2/en not_active Ceased
- 2008-10-15 KR KR1020107008300A patent/KR20100075925A/ko not_active Withdrawn
- 2008-10-15 BR BRPI0818005 patent/BRPI0818005A2/pt not_active IP Right Cessation
- 2008-10-15 PE PE2008001774A patent/PE20091392A1/es not_active Application Discontinuation
- 2008-10-15 EP EP08838649A patent/EP2211865A2/en not_active Withdrawn
- 2008-10-15 EA EA201000617A patent/EA201000617A1/ru unknown
- 2008-10-15 AR ARP080104494A patent/AR068879A1/es not_active Application Discontinuation
- 2008-10-15 JP JP2010529369A patent/JP2011500630A/ja active Pending
- 2008-10-15 MX MX2010004252A patent/MX2010004252A/es not_active Application Discontinuation
- 2008-10-15 CA CA2702942A patent/CA2702942A1/en not_active Abandoned
- 2008-10-15 AU AU2008313788A patent/AU2008313788A1/en not_active Abandoned
- 2008-10-15 CN CN200880112188A patent/CN101827596A/zh active Pending
- 2008-10-16 TW TW097139728A patent/TW200927129A/zh unknown
- 2008-10-16 CL CL2008003057A patent/CL2008003057A1/es unknown
-
2010
- 2010-03-25 IL IL204723A patent/IL204723A0/en unknown
- 2010-03-26 CR CR11341A patent/CR11341A/es not_active Application Discontinuation
- 2010-04-01 ZA ZA2010/02336A patent/ZA201002336B/en unknown
- 2010-04-14 CU CU20100065A patent/CU20100065A7/es unknown
- 2010-04-16 TN TN2010000168A patent/TN2010000168A1/fr unknown
- 2010-04-30 MA MA32802A patent/MA31796B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201002336B (en) | 2011-04-28 |
| WO2009050198A3 (en) | 2009-09-11 |
| EA201000617A1 (ru) | 2010-10-29 |
| WO2009050198A2 (en) | 2009-04-23 |
| MA31796B1 (fr) | 2010-10-01 |
| TN2010000168A1 (en) | 2011-11-11 |
| EP2211865A2 (en) | 2010-08-04 |
| JP2011500630A (ja) | 2011-01-06 |
| CL2008003057A1 (es) | 2009-06-26 |
| CR11341A (es) | 2010-05-06 |
| AU2008313788A1 (en) | 2009-04-23 |
| IL204723A0 (en) | 2010-11-30 |
| CU20100065A7 (es) | 2011-10-05 |
| KR20100075925A (ko) | 2010-07-05 |
| CN101827596A (zh) | 2010-09-08 |
| AR068879A1 (es) | 2009-12-09 |
| BRPI0818005A2 (pt) | 2015-04-14 |
| MX2010004252A (es) | 2010-04-30 |
| US20090181934A1 (en) | 2009-07-16 |
| TW200927129A (en) | 2009-07-01 |
| CA2702942A1 (en) | 2009-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |