PE20091265A1 - Nanoparticulas que contienen pioglitazona - Google Patents
Nanoparticulas que contienen pioglitazonaInfo
- Publication number
- PE20091265A1 PE20091265A1 PE2008002062A PE2008002062A PE20091265A1 PE 20091265 A1 PE20091265 A1 PE 20091265A1 PE 2008002062 A PE2008002062 A PE 2008002062A PE 2008002062 A PE2008002062 A PE 2008002062A PE 20091265 A1 PE20091265 A1 PE 20091265A1
- Authority
- PE
- Peru
- Prior art keywords
- pioglitazone
- nanoparticles containing
- containing pioglitazone
- preparations
- nanoparticle
- Prior art date
Links
- HYAFETHFCAUJAY-UHFFFAOYSA-N pioglitazone Chemical compound N1=CC(CC)=CC=C1CCOC(C=C1)=CC=C1CC1C(=O)NC(=O)S1 HYAFETHFCAUJAY-UHFFFAOYSA-N 0.000 title abstract 6
- 229960005095 pioglitazone Drugs 0.000 title abstract 3
- 239000002105 nanoparticle Substances 0.000 title abstract 2
- 229920000249 biocompatible polymer Polymers 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/422—Anti-atherosclerotic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
REFERIDA A UNA NANOPARTICULA QUE COMPRENDE PIOGLITAZONA O UNA SAL DEL MISMO Y UN POLIMERO BIOCOMPATIBLE TAL COMO UN COPOLIMERO ACIDO LACTICO-ACIDO GLICOLICO, DONDE LA PIOGLITAZONA SE ENCUENTRA EN UNA CANTIDAD DE ENTRE 0,1% A 10% EN PESO. TAMBIEN ESTA REFERIDA A UN STENT Y PREPARACIONES FARMACEUTICAS QUE COMPRENDEN DICHA PARTICULA. DICHAS PREPARACIONES SON UTILES EN EL TRATAMIENTO DE ENFERMEDADES ARTERIOESCLEROTICAS
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007322409 | 2007-12-13 | ||
| JP2008125071 | 2008-05-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20091265A1 true PE20091265A1 (es) | 2009-09-18 |
Family
ID=40440298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2008002062A PE20091265A1 (es) | 2007-12-13 | 2008-12-12 | Nanoparticulas que contienen pioglitazona |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8337896B2 (es) |
| EP (1) | EP2219625B1 (es) |
| JP (1) | JP5382879B2 (es) |
| CN (1) | CN101969934B (es) |
| AR (1) | AR069674A1 (es) |
| CL (1) | CL2008003699A1 (es) |
| ES (1) | ES2392375T3 (es) |
| PE (1) | PE20091265A1 (es) |
| TW (1) | TW200932223A (es) |
| WO (1) | WO2009075391A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2371370A1 (en) | 2010-04-01 | 2011-10-05 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Antagonists of miRNA-29 expression and their use in the prevention and treatment of aortic aneurysms and atherosclerotic plaque destabilization |
| CN103068404B (zh) * | 2010-06-11 | 2015-11-25 | 独立行政法人科学技术振兴机构 | 药物多聚物微粒及其制造方法 |
| CN101912363A (zh) * | 2010-07-29 | 2010-12-15 | 蔡海德 | 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物 |
| WO2012068476A2 (en) | 2010-11-18 | 2012-05-24 | University Of South Florida | Poly(vinyl benzoate) nanoparticles for molecular delivery |
| JP2012125180A (ja) * | 2010-12-15 | 2012-07-05 | Kowa Co | 下肢虚血モデル動物 |
| US8734898B2 (en) | 2012-09-21 | 2014-05-27 | E I Du Pont De Nemours And Company | Method for producing encapsulated nanoparticles |
| CN103006567A (zh) * | 2012-12-21 | 2013-04-03 | 中国海洋大学 | 一种包载亲水性药物的壳聚糖-聚乳酸羟基乙酸复合纳米微粒的制备方法 |
| US10232090B2 (en) * | 2013-08-23 | 2019-03-19 | Southwest Research Institute | Electrophoretically deposited strontium fluoride nanoparticle/polymer coatings for medical implants |
| JP6564369B2 (ja) | 2013-12-09 | 2019-08-21 | デュレクト コーポレイション | 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法 |
| CN109481419B (zh) * | 2019-01-16 | 2021-04-02 | 中国人民解放军陆军军医大学第一附属医院 | 一种罗格列酮纳米制剂及其制备方法和用途 |
| CO2020001235A1 (es) * | 2020-02-03 | 2021-08-09 | Univ Pontificia Bolivariana | Stent |
| US20230355542A1 (en) * | 2022-05-04 | 2023-11-09 | Yasin Oduk | Drug-eluting device with genetic and chemical therapeutics for treating or preventing vascular access dysfunctions |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT75469A (en) * | 1994-02-28 | 1997-05-28 | Medinova Med Consulting Gmbh | Drug targeting system, method for preparing same and its use |
| ES2259459T3 (es) | 1997-11-19 | 2006-10-01 | Takeda Pharmaceutical Company Limited | Nuevos inhibidores de apoptosis. |
| CA2349865C (en) * | 1999-06-21 | 2014-08-19 | Eli Lilly And Company | Synergistic use of thiazolidinediones with glucagon-like peptide-1 and agonists thereof to treat metabolic instability associated with non-insulin dependent diabetes |
| CN1507357A (zh) * | 2000-10-31 | 2004-06-23 | PRҩƷ����˾ | 提高生物活性分子传递的方法和组合物 |
| DE60237594D1 (de) | 2001-04-25 | 2010-10-21 | Takeda Pharmaceutical | Verwendung des abc-expressionspromotors pioglitazon zur behandlung von arteriosklerose obliterans |
| WO2003013609A1 (fr) | 2001-08-03 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Medicaments a liberation continue |
| JP2003113120A (ja) * | 2001-08-03 | 2003-04-18 | Takeda Chem Ind Ltd | 徐放性医薬 |
| FR2830017B1 (fr) * | 2001-09-27 | 2005-11-04 | Centre Nat Rech Scient | Materiau compose d'au moins un polymere biodegradable et de cyclodextrines |
| US20050095267A1 (en) * | 2002-12-04 | 2005-05-05 | Todd Campbell | Nanoparticle-based controlled release polymer coatings for medical implants |
| JP4707937B2 (ja) * | 2003-02-28 | 2011-06-22 | ホソカワミクロン株式会社 | 薬物含有複合粒子の製造方法および経肺製剤 |
| JP2004267283A (ja) * | 2003-03-05 | 2004-09-30 | Terumo Corp | 体内埋込医療材料および体内埋込医療器具 |
| US8119153B2 (en) * | 2004-08-26 | 2012-02-21 | Boston Scientific Scimed, Inc. | Stents with drug eluting coatings |
| BRPI0516308A2 (pt) * | 2004-10-04 | 2010-06-15 | Qlt Usa Inc | composição fluida, métodos de tratamento de uma doença ou disfunção, métodos de liberação local ou sistêmica de um agente biológico, implantes, método de formação de um implante, kit de agente biológico e usos de uma composição fluida |
| CA2612384A1 (en) * | 2005-06-15 | 2006-12-28 | Elan Pharma International, Limited | Nanoparticulate azelnidipine formulations |
| JP2007119396A (ja) | 2005-10-28 | 2007-05-17 | Hosokawa Funtai Gijutsu Kenkyusho:Kk | 核酸化合物封入ナノ粒子を含む経肺投与用医薬製剤 |
| US20070098802A1 (en) * | 2005-10-31 | 2007-05-03 | Isaac Farr | Organic nanoparticles and associated methods |
| JP4297221B2 (ja) | 2006-02-15 | 2009-07-15 | 株式会社ホソカワ粉体技術研究所 | 薬剤溶出型ステントの製造方法 |
| US20080020014A1 (en) * | 2006-07-19 | 2008-01-24 | Paul Consigny | Implantable devices containing nuclear receptor ligands for the treatment of vascular and related disorders |
| US20080026040A1 (en) * | 2006-07-31 | 2008-01-31 | Isaac Farr | Active agent-releasing dosage forms |
| JP2010523595A (ja) | 2007-04-04 | 2010-07-15 | マサチューセッツ インスティテュート オブ テクノロジー | ポリ(アミノ酸)ターゲッティング部分 |
-
2008
- 2008-12-12 PE PE2008002062A patent/PE20091265A1/es not_active Application Discontinuation
- 2008-12-12 AR ARP080105407A patent/AR069674A1/es unknown
- 2008-12-12 CL CL2008003699A patent/CL2008003699A1/es unknown
- 2008-12-12 ES ES08859992T patent/ES2392375T3/es active Active
- 2008-12-12 EP EP08859992A patent/EP2219625B1/en not_active Not-in-force
- 2008-12-12 JP JP2010523213A patent/JP5382879B2/ja not_active Expired - Fee Related
- 2008-12-12 CN CN2008801267934A patent/CN101969934B/zh not_active Expired - Fee Related
- 2008-12-12 WO PCT/JP2008/073139 patent/WO2009075391A1/en not_active Ceased
- 2008-12-12 US US12/735,035 patent/US8337896B2/en not_active Expired - Fee Related
- 2008-12-12 TW TW097148396A patent/TW200932223A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR069674A1 (es) | 2010-02-10 |
| EP2219625A1 (en) | 2010-08-25 |
| CN101969934A (zh) | 2011-02-09 |
| US20100331373A1 (en) | 2010-12-30 |
| US8337896B2 (en) | 2012-12-25 |
| JP2011506268A (ja) | 2011-03-03 |
| WO2009075391A1 (en) | 2009-06-18 |
| CN101969934B (zh) | 2012-11-21 |
| EP2219625B1 (en) | 2012-08-01 |
| ES2392375T3 (es) | 2012-12-10 |
| CL2008003699A1 (es) | 2009-10-09 |
| TW200932223A (en) | 2009-08-01 |
| JP5382879B2 (ja) | 2014-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |