PE20080347A1 - CYPROFLOXACIN AND DEXAMETASONE OPHTHALMIC SOLUTION - Google Patents
CYPROFLOXACIN AND DEXAMETASONE OPHTHALMIC SOLUTIONInfo
- Publication number
- PE20080347A1 PE20080347A1 PE2007000833A PE2007000833A PE20080347A1 PE 20080347 A1 PE20080347 A1 PE 20080347A1 PE 2007000833 A PE2007000833 A PE 2007000833A PE 2007000833 A PE2007000833 A PE 2007000833A PE 20080347 A1 PE20080347 A1 PE 20080347A1
- Authority
- PE
- Peru
- Prior art keywords
- dexametasone
- cyprofloxacin
- ophthalmic solution
- approximately
- sodium
- Prior art date
Links
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 title abstract 2
- 229940054534 ophthalmic solution Drugs 0.000 title 1
- 239000002997 ophthalmic solution Substances 0.000 title 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 abstract 1
- DIOIOSKKIYDRIQ-UHFFFAOYSA-N ciprofloxacin hydrochloride Chemical compound Cl.C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 DIOIOSKKIYDRIQ-UHFFFAOYSA-N 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 229940037001 sodium edetate Drugs 0.000 abstract 1
- 229910052938 sodium sulfate Inorganic materials 0.000 abstract 1
- 235000011152 sodium sulphate Nutrition 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA OFTALMICA EN SOLUCION PARA APLICACION TOPICA, QUE COMPRENDE: A) DEXAMETASONA MICRONIZADA APROXIMADAMENTE 0,1%; B) CLORHIDRATO DE CIPROFLOXACINO MONOHIDRATADO APROXIMADAMENTE AL 0,3%; C) CLORURO DE SODIO EN CANTIDAD SUFICIENTE PARA OBTENER 250-350mOsm/K; D) HIDROXIPROPILBETACICLODEXTRINAS AL 6%, SULFATO DE SODIO, EDETATO SODICO, CLORURO DE BENZALCONIO POLISORBATO 80 COMO SURFACTANTE NO IONICO. DICHA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE PADECIMIENTOS OCULARES CAUSADOS POR BACTERIAS Y HONGOSIT REFERS TO AN OPHTHALMIC PHARMACEUTICAL COMPOSITION IN SOLUTION FOR TOPICAL APPLICATION, WHICH INCLUDES: A) MICRONIZED DEXAMETASONE APPROXIMATELY 0.1%; B) CIPROFLOXACINE HYDROCHLORIDE MONOHYDRATED AT APPROXIMATELY 0.3%; C) SODIUM CHLORIDE IN A SUFFICIENT QUANTITY TO OBTAIN 250-350mOsm / K; D) 6% HYDROXYPROPILBETACICLODEXTRINS, SODIUM SULPHATE, SODIUM EDETATE, BENZALCONIUM CHLORIDE POLYYSORBATE 80 AS A NON-IONIC SURFACTANT. SAID COMPOSITION IS USEFUL FOR THE TREATMENT OF EYE DISEASES CAUSED BY BACTERIA AND FUNGI
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/MX2006/000062 WO2008002117A1 (en) | 2006-06-27 | 2006-06-27 | Ophthalmic solution of ciprofloxacin and dexamethasone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20080347A1 true PE20080347A1 (en) | 2008-04-11 |
Family
ID=38845821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007000833A PE20080347A1 (en) | 2006-06-27 | 2007-06-27 | CYPROFLOXACIN AND DEXAMETASONE OPHTHALMIC SOLUTION |
Country Status (3)
| Country | Link |
|---|---|
| CL (1) | CL2007001894A1 (en) |
| PE (1) | PE20080347A1 (en) |
| WO (1) | WO2008002117A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970244B (en) * | 2016-10-21 | 2020-07-14 | 武汉武药科技有限公司 | Composition containing ciprofloxacin and dexamethasone and preparation method thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6740664B2 (en) * | 1998-09-30 | 2004-05-25 | Alcon, Inc. | Methods for treating otic and ophthalmic infections |
| BR0115415A (en) * | 2000-11-15 | 2003-09-09 | Mohan A Chandavarkar | Combination drug |
| WO2004069280A1 (en) * | 2003-02-06 | 2004-08-19 | Cipla Ltd | Pharmaceutical inclusion complexes containing a steroid and optionally an antibacterial agent |
| WO2004087043A2 (en) * | 2003-02-21 | 2004-10-14 | Sun Pharmaceutical Industries Limited | Stable ophthalmic formulation containing an antibiotic and a corticosteroid |
-
2006
- 2006-06-27 WO PCT/MX2006/000062 patent/WO2008002117A1/en not_active Ceased
-
2007
- 2007-06-27 CL CL2007001894A patent/CL2007001894A1/en unknown
- 2007-06-27 PE PE2007000833A patent/PE20080347A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008002117A1 (en) | 2008-01-03 |
| CL2007001894A1 (en) | 2008-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FX | Voluntary withdrawal |