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PE20041024A1 - Sistema de liberacion controlada - Google Patents

Sistema de liberacion controlada

Info

Publication number
PE20041024A1
PE20041024A1 PE2004000292A PE2004000292A PE20041024A1 PE 20041024 A1 PE20041024 A1 PE 20041024A1 PE 2004000292 A PE2004000292 A PE 2004000292A PE 2004000292 A PE2004000292 A PE 2004000292A PE 20041024 A1 PE20041024 A1 PE 20041024A1
Authority
PE
Peru
Prior art keywords
solvent
controlled release
alcohol
release system
codisolvent
Prior art date
Application number
PE2004000292A
Other languages
English (en)
Inventor
Kristine Fraatz
Dirk Mertin
Iris Heep
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of PE20041024A1 publication Critical patent/PE20041024A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE REFIERE A UN MEDICAMENTO, QUE COMPRENDE: 1)UN COMPONENTE FARMACEUTICO ACTIVO, QUE PUEDE SER FLUOROQUINOLONA, ENROFLOXACINO, FLUPIRTINA, ENTRE OTROS; 2)80%, EN PESO, DEL TOTAL DE LA COMPOSICION, DE ACETATO ISOBUTIRATO DE SACAROSA (SAIB); 3)GLICEROLFORMAL O ISOPROPILIDENGLICEROL O UNA MEZCLA DE LOS MISMOS, COMO DISOLVENTE; Y, 4)UN ALCOHOL, FARMACEUTICAMENTE ACEPTABLE, COMO CODISOLVENTE, SELECCIONADOS DE: ETANOL, N-BUTANOL O ALCOHOL BENCILICO. LA FORMULACION DESCRITA, SE PRESENTA EN FORMA DE SOLUCIONES, PASTAS, SUSPENSION O EMULSION. EN LA APLICACION, SE DIFUNDE UNA PEQUENA CANTIDAD DE DISOLVENTE EN EL TEJIDO CIRCUNDANTE O EL LIQUIDO INTERSTICIAL Y DEJA UN DEPOSITO ALTAMENTE VISCOSO DEL QUE EL PRINCIPIO ACTIVO SE LIBERA RETARDADAMENTE
PE2004000292A 2003-03-20 2004-03-19 Sistema de liberacion controlada PE20041024A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10312346A DE10312346A1 (de) 2003-03-20 2003-03-20 Kontrolliertes Freisetzungssystem

Publications (1)

Publication Number Publication Date
PE20041024A1 true PE20041024A1 (es) 2005-01-27

Family

ID=32920993

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000292A PE20041024A1 (es) 2003-03-20 2004-03-19 Sistema de liberacion controlada

Country Status (18)

Country Link
US (1) US8231903B2 (es)
EP (1) EP1608335B1 (es)
JP (1) JP4863867B2 (es)
AR (1) AR043423A1 (es)
AT (1) ATE380017T1 (es)
AU (1) AU2004222646B2 (es)
BR (1) BRPI0408555A (es)
CA (1) CA2519351C (es)
CL (1) CL2004000566A1 (es)
DE (2) DE10312346A1 (es)
ES (1) ES2297396T3 (es)
GT (1) GT200400045A (es)
MX (1) MXPA05009910A (es)
NO (1) NO20054776L (es)
NZ (1) NZ542477A (es)
PE (1) PE20041024A1 (es)
TW (1) TW200505488A (es)
WO (1) WO2004082658A1 (es)

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US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP2959893A1 (en) 2002-12-13 2015-12-30 DURECT Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
CA2581287C (en) * 2004-09-17 2015-08-25 Durect Corporation Sustained local anesthetic composition containing bupivacaine and saib
US20070027105A1 (en) * 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
DE102006010643A1 (de) * 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102006049520A1 (de) 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin
EP2117521B1 (en) 2006-11-03 2012-06-27 Durect Corporation Transdermal delivery systems comprising bupivacaine
CA2686137C (en) * 2007-05-18 2021-01-12 Durect Corporation Improved depot formulations
WO2009088414A2 (en) 2007-12-06 2009-07-16 Durect Corporation Oral pharmaceutical dosage forms
AU2009212373B2 (en) * 2008-02-08 2013-10-03 Foresee Pharmaceuticals Co., Ltd. Non-polymeric compositions for controlled drug delivery
US7923447B2 (en) * 2008-03-17 2011-04-12 Academic Pharmaceuticals Incorporated Parenteral solutions containing metolazone
WO2009145674A1 (ru) * 2008-05-28 2009-12-03 Учреждение Российской Академии Наук Институт Биохимической Физики Им. Н.М. Эмануэля Ран (Ибхф Ран) Средство для повышения октанового числа бензинового автомобильного топлива
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
CN102764257B (zh) * 2011-10-21 2013-09-25 四川百利药业有限责任公司 一种马来酸氟吡汀缓释片剂
CA2905131A1 (en) 2013-03-15 2014-09-18 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
CN103520167A (zh) * 2013-10-30 2014-01-22 游锡火 含硫酸头孢喹诺和甲磺酸达氟沙星的长效注射剂
CN103520099A (zh) * 2013-10-30 2014-01-22 王玉万 含有效成份为沃尼妙林的长效注射剂
CN103520168A (zh) * 2013-10-30 2014-01-22 游锡火 含延胡索酸泰妙菌素的复方注射剂
CN103550149A (zh) * 2013-10-30 2014-02-05 游锡火 含抗寄生虫药物长效注射剂的制备技术
CN103550150B (zh) * 2013-10-30 2016-06-08 北京中农华威制药有限公司 改进的含二甲基硅油的注射剂
CN103520098A (zh) * 2013-10-30 2014-01-22 王玉万 恩诺沙星兽用长效注射剂的制备方法
CN103550148A (zh) * 2013-10-30 2014-02-05 游锡火 延胡索酸泰妙菌素长效注射剂制备方法
CN103536531A (zh) * 2013-10-30 2014-01-29 王玉万 甲磺酸达氟沙星长效注射剂制备方法
KR102413459B1 (ko) 2016-07-06 2022-06-24 듀렉트 코퍼레이션 약물 조성물, 장벽 층 및 약물 층을 갖는 경구 투여 형태
CN111989314B (zh) 2018-04-25 2024-04-30 拜耳动物保健有限责任公司 喹诺酮甲酸酯水解的方法
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
EP4277702A1 (en) 2021-01-12 2023-11-22 Durect Corporation Sustained release drug delivery systems and related methods

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Also Published As

Publication number Publication date
US20090246277A9 (en) 2009-10-01
AR043423A1 (es) 2005-07-27
US8231903B2 (en) 2012-07-31
JP4863867B2 (ja) 2012-01-25
NO20054776L (no) 2005-10-17
NZ542477A (en) 2009-02-28
GT200400045A (es) 2004-10-21
CL2004000566A1 (es) 2005-02-04
DE502004005652D1 (de) 2008-01-17
WO2004082658A1 (de) 2004-09-30
CA2519351A1 (en) 2004-09-30
AU2004222646B2 (en) 2010-04-29
EP1608335B1 (de) 2007-12-05
ATE380017T1 (de) 2007-12-15
BRPI0408555A (pt) 2006-03-21
ES2297396T3 (es) 2008-05-01
DE10312346A1 (de) 2004-09-30
TW200505488A (en) 2005-02-16
MXPA05009910A (es) 2005-11-04
US20060034926A1 (en) 2006-02-16
AU2004222646A1 (en) 2004-09-30
CA2519351C (en) 2012-02-07
JP2006520346A (ja) 2006-09-07
EP1608335A1 (de) 2005-12-28

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