PE20030617A1 - Aminoacidos, procedimiento para su preparacion y medicamentos que los contienen - Google Patents
Aminoacidos, procedimiento para su preparacion y medicamentos que los contienenInfo
- Publication number
- PE20030617A1 PE20030617A1 PE2001000970A PE2001000970A PE20030617A1 PE 20030617 A1 PE20030617 A1 PE 20030617A1 PE 2001000970 A PE2001000970 A PE 2001000970A PE 2001000970 A PE2001000970 A PE 2001000970A PE 20030617 A1 PE20030617 A1 PE 20030617A1
- Authority
- PE
- Peru
- Prior art keywords
- amino
- acid
- methyl
- amino acids
- procedure
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- DBYORPJVMYVSIB-UHFFFAOYSA-N 2-amino-3-methyldecanoic acid Chemical compound CCCCCCCC(C)C(N)C(O)=O DBYORPJVMYVSIB-UHFFFAOYSA-N 0.000 abstract 1
- MRVKKJOUYHWMOC-UHFFFAOYSA-N 2-amino-3-methylheptanoic acid Chemical compound CCCCC(C)C(N)C(O)=O MRVKKJOUYHWMOC-UHFFFAOYSA-N 0.000 abstract 1
- JPQVQBDYMBUCDK-UHFFFAOYSA-N 2-amino-3-methylnonanoic acid Chemical compound CCCCCCC(C)C(N)C(O)=O JPQVQBDYMBUCDK-UHFFFAOYSA-N 0.000 abstract 1
- SMERIVVDKIKDOU-UHFFFAOYSA-N 2-amino-3-methyloctanoic acid Chemical compound CCCCCC(C)C(N)C(O)=O SMERIVVDKIKDOU-UHFFFAOYSA-N 0.000 abstract 1
- YSDTUYVBODERRI-UHFFFAOYSA-N 2-amino-3-methylundecanoic acid Chemical compound CCCCCCCCC(C)C(N)C(O)=O YSDTUYVBODERRI-UHFFFAOYSA-N 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002981 neuropathic effect Effects 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10048715A DE10048715A1 (de) | 2000-09-30 | 2000-09-30 | Verwendung von Aminosäure zur Behandlung von Schmerz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030617A1 true PE20030617A1 (es) | 2003-08-02 |
Family
ID=7658376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000970A PE20030617A1 (es) | 2000-09-30 | 2001-09-28 | Aminoacidos, procedimiento para su preparacion y medicamentos que los contienen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20030229145A1 (de) |
| EP (1) | EP1326826A1 (de) |
| JP (1) | JP2004511459A (de) |
| AR (1) | AR034265A1 (de) |
| AU (1) | AU2001289936A1 (de) |
| CA (1) | CA2424089A1 (de) |
| DE (1) | DE10048715A1 (de) |
| HU (1) | HUP0302970A2 (de) |
| MX (1) | MXPA03002740A (de) |
| NZ (1) | NZ525417A (de) |
| PE (1) | PE20030617A1 (de) |
| PL (1) | PL361629A1 (de) |
| WO (1) | WO2002030871A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NI200300043A (es) | 2002-03-28 | 2003-11-05 | Warner Lambert Co | AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA. |
| US7659305B2 (en) | 2002-10-31 | 2010-02-09 | Pfizer Inc. | Therapeutic proline derivatives |
| NZ567457A (en) | 2002-12-13 | 2009-08-28 | Warner Lambert Co | Alpha-2-delta ligand to treat lower urinary tract symptoms |
| CA2451267A1 (en) | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
| MXPA06002789A (es) | 2003-09-12 | 2006-06-14 | Pfizer | Combinaciones que comprenden ligandos alfa-2-delta. |
| WO2005030703A1 (en) | 2003-09-25 | 2005-04-07 | Warner-Lambert Company Llc | PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE α2δ- PROTEIN |
| US7354955B2 (en) | 2004-01-07 | 2008-04-08 | Abbott Laboratories | (2S)-amino(phenyl)acetic acid and derivatives as α2δ voltage-gated calcium channel ligands |
| DE102004022572B4 (de) | 2004-05-07 | 2012-02-16 | Infineon Technologies Ag | Integratorschaltung |
| CN101166524B (zh) * | 2005-04-28 | 2010-12-22 | 辉瑞有限公司 | 氨基酸衍生物 |
| US8278355B2 (en) | 2006-09-12 | 2012-10-02 | Therexcell Pharma Inc. | Isovaline for treatment of pain |
| CN102058885B (zh) | 2006-12-22 | 2013-04-10 | 瑞蔻达蒂爱尔兰有限公司 | 采用α2δ配体和NSAID的下泌尿道疾病的联合治疗 |
| CN116655501A (zh) * | 2023-05-23 | 2023-08-29 | 岳阳市康利医药化工有限公司 | 一种异氰基乙酸乙酯工艺流程中的优化合成方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2854627C2 (de) * | 1978-12-18 | 1980-07-03 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Verfahren zur Herstellung von Aminocarbonsäurehydrochloriden bzw. Diaminocarbonsäure-di-hydrochloriden |
| CA1255037A (en) * | 1984-06-29 | 1989-05-30 | Barry L. Dickinson | Protective helmet made from a polyarylate |
| DE3664632D1 (en) * | 1985-04-05 | 1989-08-31 | Texaco Development Corp | Process for the synthesis of n-acetyl amino acids from olefins, acetamide and syngas |
| DE68912822T2 (de) * | 1988-05-16 | 1994-06-09 | Searle & Co | 2-Amino-4,5-methylenadipinsäure-Verbindungen für die Behandlung von CNS-Erkrankungen. |
| NL9101380A (nl) * | 1991-08-13 | 1993-03-01 | Dsm Nv | Werkwijze voor de bereiding van een alfa-aminozuur, de overeenkomstige ester en amide. |
| DE4425068A1 (de) * | 1994-07-15 | 1996-01-18 | Degussa | Verfahren zur Herstellung optisch aktiver L-Aminosäuren, neue optisch aktive L-Aminosäuren mit raumerfüllenden Seitengruppen und deren Verwendung |
| PL185991B1 (pl) * | 1996-03-14 | 2003-09-30 | Warner Lambert Co | Nowe podstawione cykliczne aminokwasy i kompozycja farmaceutyczna |
| GB9621789D0 (en) * | 1996-10-18 | 1996-12-11 | Lilly Industries Ltd | Pharmaceutical compounds |
| JP3847934B2 (ja) * | 1997-02-14 | 2006-11-22 | 株式会社カネカ | γ−オキソ−ホモフェニルアラニン誘導体及びそれを還元してなるホモフェニルアラニン誘導体の製造方法 |
| CN1251579A (zh) * | 1997-04-07 | 2000-04-26 | Axys药物公司 | 治疗与丝氨酸蛋白酶－特别是类胰蛋白酶－活性有关的疾病的化合物与组合物 |
| WO1999026933A1 (en) * | 1997-11-26 | 1999-06-03 | Axys Pharmaceuticals, Inc. | Substituted amidinoaryl derivatives and their use as anticoagulants |
| JP4205191B2 (ja) * | 1997-12-26 | 2009-01-07 | ダイセル化学工業株式会社 | α−アミノニトリル誘導体及びα−アミノ酸の製造方法 |
-
2000
- 2000-09-30 DE DE10048715A patent/DE10048715A1/de not_active Withdrawn
-
2001
- 2001-09-28 PL PL36162901A patent/PL361629A1/xx not_active Application Discontinuation
- 2001-09-28 EP EP01969790A patent/EP1326826A1/de not_active Withdrawn
- 2001-09-28 JP JP2002534260A patent/JP2004511459A/ja not_active Withdrawn
- 2001-09-28 AU AU2001289936A patent/AU2001289936A1/en not_active Abandoned
- 2001-09-28 CA CA002424089A patent/CA2424089A1/en not_active Abandoned
- 2001-09-28 WO PCT/EP2001/011230 patent/WO2002030871A1/de not_active Ceased
- 2001-09-28 NZ NZ525417A patent/NZ525417A/xx not_active IP Right Cessation
- 2001-09-28 AR ARP010104585A patent/AR034265A1/es not_active Application Discontinuation
- 2001-09-28 MX MXPA03002740A patent/MXPA03002740A/es unknown
- 2001-09-28 HU HU0302970A patent/HUP0302970A2/hu unknown
- 2001-09-28 PE PE2001000970A patent/PE20030617A1/es not_active Application Discontinuation
-
2003
- 2003-03-31 US US10/402,129 patent/US20030229145A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ525417A (en) | 2005-11-25 |
| DE10048715A1 (de) | 2004-05-19 |
| US20030229145A1 (en) | 2003-12-11 |
| MXPA03002740A (es) | 2003-07-28 |
| EP1326826A1 (de) | 2003-07-16 |
| WO2002030871A1 (de) | 2002-04-18 |
| JP2004511459A (ja) | 2004-04-15 |
| PL361629A1 (en) | 2004-10-04 |
| CA2424089A1 (en) | 2003-03-28 |
| AR034265A1 (es) | 2004-02-18 |
| HUP0302970A2 (hu) | 2003-12-29 |
| AU2001289936A1 (en) | 2002-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |