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PE20000183A1 - Citoquinas de mamiferos y reactivos relacionados - Google Patents

Citoquinas de mamiferos y reactivos relacionados

Info

Publication number
PE20000183A1
PE20000183A1 PE1998000663A PE00066398A PE20000183A1 PE 20000183 A1 PE20000183 A1 PE 20000183A1 PE 1998000663 A PE1998000663 A PE 1998000663A PE 00066398 A PE00066398 A PE 00066398A PE 20000183 A1 PE20000183 A1 PE 20000183A1
Authority
PE
Peru
Prior art keywords
refers
protein
ilb30
antibody
primate
Prior art date
Application number
PE1998000663A
Other languages
English (en)
Inventor
J Fernando Bazan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25413278&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20000183(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20000183A1 publication Critical patent/PE20000183A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE REFIERE A UN POLINUCLEOTIDO AISLADO O RECOMBINANTE QUE CODIFICA CITOQUINA O LINFOQUINAS RELACIONADAS CON FACTOR ESTIMULADOR DE LA COLONIA DE GRANULOCITOS (G-CFS) O INTERLEUCINA (IL-6); QUE COMPRENDE 17 AMINOACIDOS CONTIGUOS A UNA SECUENCIA DE AMINOACIDO NATURAL ILB30 DE PRIMATE, ROEDOR O CERDO; QUE SE CARACTERIZA PORQUE SE HIBRIDIZA A 55°C, CON MENOS DE 500 mg DE SAL Y 50% DE FORMAMIDA A LAS PORCIONES CODIFICADORAS DE LA SECUENCIA DE ILB30 DE UN PRIMATE O ROEDOR Y QUE COMPRENDE POR LO MENOS 35 NUCLEOTIDOS CONTIGUOS A LA SECUENCIA DE ACIDO NUCLEICO NATURAL ILB30 DE PRIMATE O ROEDOR. TAMBIEN SE REFIERE A UNA CELULA HUESPED QUE CONTIENE EL VECTOR DE EXPRESION EL QUE CONTIENE EL POLINUCLEOTIDO; TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA PREPARAR UN POLIPEPTIDO ANTIGENICO RECOMBINANTE; TAMBIEN SE REFIERE A UN METODO PARA LA DETECCION DE UN POLINUCLEOTIDO; TAMBIEN SE REFIERE A UN COMPUESTO DE ADHESION (ANTICUERPO) QUE SE ADHIERE ESPECIFICAMENTE A UNA PROTEINA ILB30, EL SITIO DE ADHESION DE ANTICUERPO ES ESPECIFICAMENTE INMUNOREACTIVO CON UN POLIPEPTIDO O ESTA CONTRA UNA PROTEINA ILB30 HUMANA PRODUCIDA EN FORMA PURIFICADA O RECOMBINANTE O UN ANTICUERPO MONOCLONAL Fab o F(ab)2
PE1998000663A 1997-07-25 1998-07-23 Citoquinas de mamiferos y reactivos relacionados PE20000183A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90090597A 1997-07-25 1997-07-25

Publications (1)

Publication Number Publication Date
PE20000183A1 true PE20000183A1 (es) 2000-03-11

Family

ID=25413278

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998000663A PE20000183A1 (es) 1997-07-25 1998-07-23 Citoquinas de mamiferos y reactivos relacionados

Country Status (28)

Country Link
EP (3) EP2233574A1 (es)
JP (5) JP4316133B2 (es)
KR (1) KR100666835B1 (es)
CN (2) CN1271387A (es)
AR (2) AR017510A1 (es)
AT (1) ATE443142T1 (es)
AU (1) AU741046B2 (es)
BR (1) BR9811039A (es)
CA (1) CA2296272C (es)
CO (1) CO4810232A1 (es)
CZ (1) CZ300958B6 (es)
DE (1) DE69841161D1 (es)
DK (2) DK2100959T3 (es)
ES (2) ES2610483T3 (es)
HU (1) HU230629B1 (es)
ID (1) ID28114A (es)
IL (3) IL134068A0 (es)
LT (1) LT2100959T (es)
MY (1) MY157028A (es)
NO (1) NO329329B1 (es)
NZ (1) NZ502391A (es)
PE (1) PE20000183A1 (es)
PL (1) PL197150B1 (es)
PT (2) PT1002084E (es)
SK (1) SK287198B6 (es)
TW (1) TWI237057B (es)
WO (1) WO1999005280A1 (es)
ZA (1) ZA986596B (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060284A (en) 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
EP1033373B1 (en) * 1997-10-23 2006-06-14 Nippon Institute for Biological Science Feline granulocyte colony-stimulating factor
AU2661199A (en) * 1998-02-06 1999-08-23 Schering Corporation Mammalian receptor proteins; related reagents and methods
DE69942607D1 (de) * 1998-04-14 2010-09-02 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
CN100529076C (zh) * 1999-09-09 2009-08-19 先灵公司 哺乳动物细胞因子、相关试剂和方法
AU2005202420B2 (en) * 1999-09-09 2008-08-07 Merck Sharp & Dohme Corp. Mammalian cytokines; related reagents and methods
NZ539271A (en) 2002-10-30 2008-12-24 Genentech Inc Inhibition of the production of proinflammatory cytokine interleukin-17 (IL-17) by T cells, using an antagonist of interleukin-23 (IL-23)
US7247711B2 (en) 2003-05-09 2007-07-24 Centocor, Inc. IL-23p40 specific antibody
WO2005108425A1 (en) * 2004-05-10 2005-11-17 Cytos Biotechnology Ag Il-23 p19 antigen array and uses thereof
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
HUE042561T2 (hu) 2005-06-30 2019-07-29 Janssen Biotech Inc Anti-IL-23-ellenanyagok, készítmények, eljárások és alkalmazások
ES2807928T3 (es) 2005-12-29 2021-02-24 Janssen Biotech Inc Anticuerpos anti-IL-23 humanos, composiciones, procedimientos y usos
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
US7790862B2 (en) 2006-06-13 2010-09-07 Zymogenetics, Inc. IL-17 and IL-23 antagonists and methods of using the same
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Ｉｌ-２３拮抗劑於治療感染之用途
WO2009068631A1 (en) 2007-11-27 2009-06-04 Ablynx N.V. Method for obtaining polypeptide constructs comprising two or more single domain antibodies
CN102083858B (zh) 2008-05-05 2015-01-14 诺维莫尼公司 抗il-17a/il-17f交叉反应性抗体及其使用方法
CN102458437B (zh) 2009-05-05 2015-06-10 诺维莫尼公司 抗il-17f抗体及其使用方法
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
PL2635601T3 (pl) 2010-11-04 2017-02-28 Boehringer Ingelheim International Gmbh Przeciwciała anty-il-23
PL3326649T3 (pl) 2012-05-03 2022-04-25 Boehringer Ingelheim International Gmbh Przeciwciała anty-il-23p19
EP3689369A1 (en) 2013-03-15 2020-08-05 Amgen, Inc Methods for treating psoriasis using an anti-il-23 antibody
SG10201805015TA (en) 2013-03-15 2018-07-30 Amgen Inc Methods for treating crohn's disease using an anti-il23 antibody
EP3708679A1 (en) 2014-07-24 2020-09-16 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
EA039598B9 (ru) 2014-09-03 2022-03-10 Бёрингер Ингельхайм Интернациональ Гмбх Соединение, нацеленное на ил-23а и фно-альфа, и его применение
KR20240158362A (ko) 2015-02-04 2024-11-04 베링거 인겔하임 인터내셔날 게엠베하 염증성 질환의 치료 방법
WO2017049035A1 (en) 2015-09-17 2017-03-23 Amgen Inc. Prediction of clinical response to il23-antagonists using il23 pathway biomarkers
BR112018012626A2 (pt) 2015-12-22 2018-12-04 Amgen Inc ccl20 como um preditor de resposta clínica a antagonistas de il23
KR20210032441A (ko) 2018-07-13 2021-03-24 아스트라제네카 콜라보레이션 벤처스, 엘엘씨 브라지쿠맙을 이용한 궤양성 대장염의 치료
CA3120237A1 (en) 2018-11-20 2020-05-28 Janssen Biotech, Inc. Safe and effective method of treating psoriasis with anti-il-23 specific antibody
CA3138241A1 (en) 2019-05-23 2020-11-26 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
AU2020409124A1 (en) 2019-12-20 2022-06-30 Novarock Biotherapeutics, Ltd. Anti-interleukin-23 p19 antibodies and methods of use thereof
US12258393B2 (en) 2020-05-21 2025-03-25 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2046920B1 (es) 1969-06-19 1974-05-03 Citizen Watch Co Ltd
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
EP0088994B1 (en) 1982-03-15 1991-06-19 Schering Corporation Hybrid dna, binding composition prepared thereby and processes therefor
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5891680A (en) * 1995-02-08 1999-04-06 Whitehead Institute For Biomedical Research Bioactive fusion proteins comprising the p35 and p40 subunits of IL-12
DE69942607D1 (de) * 1998-04-14 2010-09-02 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein

Also Published As

Publication number Publication date
PT2100959T (pt) 2017-01-09
DK2100959T3 (en) 2017-01-30
ES2610483T3 (es) 2017-04-27
CA2296272A1 (en) 1999-02-04
CN101851286A (zh) 2010-10-06
ID28114A (id) 2001-05-03
AU741046B2 (en) 2001-11-22
CA2296272C (en) 2012-03-13
EP2100959A3 (en) 2009-10-14
KR20010022214A (ko) 2001-03-15
PT1002084E (pt) 2009-12-16
CO4810232A1 (es) 1999-06-30
HK1024932A1 (en) 2000-10-27
EP1002084B1 (en) 2009-09-16
EP2233574A1 (en) 2010-09-29
JP2015037405A (ja) 2015-02-26
JP2005323610A (ja) 2005-11-24
WO1999005280A1 (en) 1999-02-04
CZ2000263A3 (cs) 2000-06-14
SK287198B6 (sk) 2010-03-08
DK1002084T3 (da) 2010-01-04
HUP0004019A3 (en) 2003-08-28
EP1002084A1 (en) 2000-05-24
EP2100959A2 (en) 2009-09-16
SK912000A3 (en) 2000-09-12
NO329329B1 (no) 2010-09-27
JP2013034480A (ja) 2013-02-21
JP2001511347A (ja) 2001-08-14
KR100666835B1 (ko) 2007-01-11
IL134068A0 (en) 2001-04-30
MY157028A (en) 2016-04-15
JP2010011863A (ja) 2010-01-21
NZ502391A (en) 2002-12-20
AR017510A1 (es) 2001-09-12
NO20000343D0 (no) 2000-01-24
TWI237057B (en) 2005-08-01
CZ300958B6 (cs) 2009-09-23
AU8589498A (en) 1999-02-16
BR9811039A (pt) 2000-08-08
AR086483A2 (es) 2013-12-18
IL205765A (en) 2015-07-30
IL205765A0 (en) 2011-07-31
IL134068A (en) 2010-11-30
HU230629B1 (hu) 2017-04-28
NO20000343L (no) 2000-03-24
PL338262A1 (en) 2000-10-09
DE69841161D1 (de) 2009-10-29
HUP0004019A2 (en) 2001-03-28
ZA986596B (en) 1999-02-08
LT2100959T (lt) 2017-01-10
EP2100959B1 (en) 2016-12-07
ATE443142T1 (de) 2009-10-15
CN1271387A (zh) 2000-10-25
PL197150B1 (pl) 2008-03-31
JP4316133B2 (ja) 2009-08-19
ES2331762T3 (es) 2010-01-14

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