PE100198A1 - Formulaciones en aerosol de furoato de mometasona sin clorofluorocarburos - Google Patents
Formulaciones en aerosol de furoato de mometasona sin clorofluorocarburosInfo
- Publication number
- PE100198A1 PE100198A1 PE1997000760A PE00076097A PE100198A1 PE 100198 A1 PE100198 A1 PE 100198A1 PE 1997000760 A PE1997000760 A PE 1997000760A PE 00076097 A PE00076097 A PE 00076097A PE 100198 A1 PE100198 A1 PE 100198A1
- Authority
- PE
- Peru
- Prior art keywords
- chlorofluorocarbes
- approximately
- aerosol formulations
- ethanol
- momethasone furoate
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000000443 aerosol Substances 0.000 title abstract 3
- SMNDYUVBFMFKNZ-UHFFFAOYSA-N 2-furoic acid Chemical compound OC(=O)C1=CC=CO1 SMNDYUVBFMFKNZ-UHFFFAOYSA-N 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- LFQSCWFLJHTTHZ-HQMMCQRPSA-N Ethanol-14C Chemical compound C[14CH2]O LFQSCWFLJHTTHZ-HQMMCQRPSA-N 0.000 abstract 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
- YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 abstract 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005642 Oleic acid Substances 0.000 abstract 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
- 229960002744 mometasone furoate Drugs 0.000 abstract 1
- WOFMFGQZHJDGCX-ZULDAHANSA-N mometasone furoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(Cl)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@H]1C)C(=O)CCl)C(=O)C1=CC=CO1 WOFMFGQZHJDGCX-ZULDAHANSA-N 0.000 abstract 1
- 239000006199 nebulizer Substances 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
UNA FORMULACION DE AEROSOL EN SUSPENSION QUE COMPRENDE 1,1,1,2,3,3,3-HEPTAFLUOROPROPANO, DE APROXIMADAMENTE 1% A 10% POR PESO DE ETANOL, Y FUROATO DE MOMETASONA MICRONIZADO EN CONCENTRACIONES DE POR LO MENOS APROXIMADAMENTE 1% DE LA CONCENTRACION DE ETANOL, FORMULACION QUE OPTATIVAMENTE CONTIENE ADEMAS UN SURFACTANTE QUE PUEDE SER ACIDO OLEICO, DICHA FORMULACION DE AEROSOL ESTA CONTENIDA EN UN NEBULIZADOR DE DOSIS MEDIDA QUE DISPENSA UNA CANTIDAD REGULADA DE APROXIMADAMENTE 10 MICROGRAMOS A APROXIMADAMENTE 500 MICROGRAMOS DE FUROATO DE MOMETASONA CON UNA SOLA OPERACION DE ACCIONAMIENTO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70536896A | 1996-08-29 | 1996-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE100198A1 true PE100198A1 (es) | 1999-01-11 |
Family
ID=24833161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997000760A PE100198A1 (es) | 1996-08-29 | 1997-08-26 | Formulaciones en aerosol de furoato de mometasona sin clorofluorocarburos |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0927037B1 (es) |
| JP (1) | JP3264496B2 (es) |
| KR (1) | KR100316358B1 (es) |
| CN (1) | CN1162157C (es) |
| AR (1) | AR008309A1 (es) |
| AT (1) | ATE202936T1 (es) |
| AU (1) | AU719079B2 (es) |
| BR (1) | BR9711445A (es) |
| CA (1) | CA2263905C (es) |
| CO (1) | CO4900027A1 (es) |
| CZ (1) | CZ294064B6 (es) |
| DE (1) | DE69705628T2 (es) |
| DK (1) | DK0927037T3 (es) |
| ES (1) | ES2159148T3 (es) |
| GR (1) | GR3036674T3 (es) |
| HU (1) | HU227915B1 (es) |
| ID (1) | ID18137A (es) |
| IL (1) | IL128714A (es) |
| MY (1) | MY117377A (es) |
| NO (1) | NO322528B1 (es) |
| NZ (1) | NZ334112A (es) |
| PE (1) | PE100198A1 (es) |
| PL (1) | PL189036B1 (es) |
| PT (1) | PT927037E (es) |
| SA (1) | SA97180339B1 (es) |
| SK (1) | SK282147B6 (es) |
| TR (1) | TR199900379T2 (es) |
| TW (1) | TW475901B (es) |
| WO (1) | WO1998008519A1 (es) |
| ZA (1) | ZA977668B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874481A (en) * | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
| US6946117B1 (en) | 1997-09-29 | 2005-09-20 | Nektar Therapeutics | Stabilized preparations for use in nebulizers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6433040B1 (en) | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| CA2382133C (en) | 2000-05-10 | 2010-11-23 | Alliance Pharmaceutical Corporation | Phospholipid-based powders for drug delivery |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| TWI324934B (en) * | 2001-08-28 | 2010-05-21 | Schering Corp | Pharmaceutical compositions for the treatment of asthma |
| WO2003053411A1 (en) | 2001-12-19 | 2003-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| GB0207906D0 (en) | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
| JP2005536538A (ja) * | 2002-08-23 | 2005-12-02 | シェーリング コーポレイション | 薬学的組成物 |
| MXPA05002248A (es) * | 2002-08-27 | 2005-06-08 | Schering Corp | Procedimiento para producir formulaciones de inhalador de dosis medida. |
| EP1925293A3 (en) * | 2003-10-20 | 2010-01-13 | Schering Corporation | Pharmaceutical aerosol compositions |
| KR20060106823A (ko) * | 2003-10-20 | 2006-10-12 | 쉐링 코포레이션 | 약제학적 에어로졸 조성물 |
| EP2117504A1 (en) * | 2007-02-09 | 2009-11-18 | Schering Corporation | Stable pharmaceutical drug aerosols |
| CN107961217B (zh) * | 2016-10-18 | 2021-06-29 | 天津金耀集团有限公司 | 一种糠酸莫米松气雾剂组合物 |
| CN107951893B (zh) * | 2016-10-18 | 2022-04-26 | 天津金耀集团有限公司 | 一种糠酸莫米松粉吸入剂组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5439670A (en) * | 1989-11-28 | 1995-08-08 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| SK140493A3 (en) * | 1991-06-10 | 1994-10-05 | Schering Corp | Non-chlorofluorocarbon aerosol formulations |
| ATE226067T1 (de) * | 1991-06-10 | 2002-11-15 | Schering Corp | Fluorchlorkohlenwasserstofffreie aerosolformulierungen |
| PE44995A1 (es) * | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
-
1997
- 1997-08-26 CZ CZ1999632A patent/CZ294064B6/cs not_active IP Right Cessation
- 1997-08-26 HU HU9902675A patent/HU227915B1/hu unknown
- 1997-08-26 PT PT97940582T patent/PT927037E/pt unknown
- 1997-08-26 TR TR1999/00379T patent/TR199900379T2/xx unknown
- 1997-08-26 IL IL12871497A patent/IL128714A/xx not_active IP Right Cessation
- 1997-08-26 ES ES97940582T patent/ES2159148T3/es not_active Expired - Lifetime
- 1997-08-26 AR ARP970103860A patent/AR008309A1/es active IP Right Grant
- 1997-08-26 KR KR1019997001588A patent/KR100316358B1/ko not_active Expired - Lifetime
- 1997-08-26 CN CNB97198980XA patent/CN1162157C/zh not_active Expired - Lifetime
- 1997-08-26 AU AU42329/97A patent/AU719079B2/en not_active Expired
- 1997-08-26 SK SK253-99A patent/SK282147B6/sk not_active IP Right Cessation
- 1997-08-26 ID IDP972976A patent/ID18137A/id unknown
- 1997-08-26 TW TW086112270A patent/TW475901B/zh not_active IP Right Cessation
- 1997-08-26 JP JP51173198A patent/JP3264496B2/ja not_active Expired - Lifetime
- 1997-08-26 AT AT97940582T patent/ATE202936T1/de active
- 1997-08-26 DK DK97940582T patent/DK0927037T3/da active
- 1997-08-26 PE PE1997000760A patent/PE100198A1/es not_active IP Right Cessation
- 1997-08-26 CA CA002263905A patent/CA2263905C/en not_active Expired - Lifetime
- 1997-08-26 MY MYPI97003925A patent/MY117377A/en unknown
- 1997-08-26 ZA ZA9707668A patent/ZA977668B/xx unknown
- 1997-08-26 SA SA97180339A patent/SA97180339B1/ar unknown
- 1997-08-26 WO PCT/US1997/014708 patent/WO1998008519A1/en not_active Ceased
- 1997-08-26 CO CO97049283A patent/CO4900027A1/es unknown
- 1997-08-26 EP EP97940582A patent/EP0927037B1/en not_active Expired - Lifetime
- 1997-08-26 BR BR9711445A patent/BR9711445A/pt active Search and Examination
- 1997-08-26 DE DE69705628T patent/DE69705628T2/de not_active Expired - Lifetime
- 1997-08-26 NZ NZ334112A patent/NZ334112A/xx not_active IP Right Cessation
- 1997-08-26 PL PL97331828A patent/PL189036B1/pl unknown
-
1999
- 1999-02-26 NO NO19990956A patent/NO322528B1/no not_active IP Right Cessation
-
2001
- 2001-09-20 GR GR20010401531T patent/GR3036674T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| MK | Expiration of term |