AR008309A1 - Formulaciones de aerosol en suspensión de furoato de mometasona , usos de de las mismas e inhalador de dosis de medida - Google Patents
Formulaciones de aerosol en suspensión de furoato de mometasona , usos de de las mismas e inhalador de dosis de medidaInfo
- Publication number
- AR008309A1 AR008309A1 ARP970103860A ARP970103860A AR008309A1 AR 008309 A1 AR008309 A1 AR 008309A1 AR P970103860 A ARP970103860 A AR P970103860A AR P970103860 A ARP970103860 A AR P970103860A AR 008309 A1 AR008309 A1 AR 008309A1
- Authority
- AR
- Argentina
- Prior art keywords
- formulations
- mometasone furoate
- suspension aerosol
- dose inhaler
- measuring dose
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000000443 aerosol Substances 0.000 title abstract 2
- 229960002744 mometasone furoate Drugs 0.000 title abstract 2
- WOFMFGQZHJDGCX-ZULDAHANSA-N mometasone furoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(Cl)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@H]1C)C(=O)CCl)C(=O)C1=CC=CO1 WOFMFGQZHJDGCX-ZULDAHANSA-N 0.000 title abstract 2
- 239000000725 suspension Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
- YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 abstract 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005642 Oleic acid Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
- 239000006199 nebulizer Substances 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Abstract
Formulaciones de aerosol en suspensión que exhiben tamanos de partículas estables, que contienen furoato de mometasona, de aproximadamente 1 aaproximadamente 10 por ciento por peso de etanol y 1,1,1,2,3,3,3- heptafluoropropano comoi mpelente. Se puede incluir asimismo un surfactante,tal como ácido oleico. Estas formulaciones son adecuadas para utilizar en nebulizadores de dosis medida. Asimismo incluye un nebulizador de dosis medidaque contiene dicha formulación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70536896A | 1996-08-29 | 1996-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR008309A1 true AR008309A1 (es) | 1999-12-29 |
Family
ID=24833161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970103860A AR008309A1 (es) | 1996-08-29 | 1997-08-26 | Formulaciones de aerosol en suspensión de furoato de mometasona , usos de de las mismas e inhalador de dosis de medida |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0927037B1 (es) |
| JP (1) | JP3264496B2 (es) |
| KR (1) | KR100316358B1 (es) |
| CN (1) | CN1162157C (es) |
| AR (1) | AR008309A1 (es) |
| AT (1) | ATE202936T1 (es) |
| AU (1) | AU719079B2 (es) |
| BR (1) | BR9711445A (es) |
| CA (1) | CA2263905C (es) |
| CO (1) | CO4900027A1 (es) |
| CZ (1) | CZ294064B6 (es) |
| DE (1) | DE69705628T2 (es) |
| DK (1) | DK0927037T3 (es) |
| ES (1) | ES2159148T3 (es) |
| GR (1) | GR3036674T3 (es) |
| HU (1) | HU227915B1 (es) |
| ID (1) | ID18137A (es) |
| IL (1) | IL128714A (es) |
| MY (1) | MY117377A (es) |
| NO (1) | NO322528B1 (es) |
| NZ (1) | NZ334112A (es) |
| PE (1) | PE100198A1 (es) |
| PL (1) | PL189036B1 (es) |
| PT (1) | PT927037E (es) |
| SA (1) | SA97180339B1 (es) |
| SK (1) | SK282147B6 (es) |
| TR (1) | TR199900379T2 (es) |
| TW (1) | TW475901B (es) |
| WO (1) | WO1998008519A1 (es) |
| ZA (1) | ZA977668B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874481A (en) * | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
| US6946117B1 (en) | 1997-09-29 | 2005-09-20 | Nektar Therapeutics | Stabilized preparations for use in nebulizers |
| US6433040B1 (en) | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| PT1280520E (pt) | 2000-05-10 | 2014-12-16 | Novartis Ag | Pós à base de fosfolípidos para administração de fármacos |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| AR036358A1 (es) * | 2001-08-28 | 2004-09-01 | Schering Corp | Un inhalador de dosis medidas que contiene una formulacion de suspension en aerosol para inhalacion, un proceso para la produccion de la formulacion, el producto y el uso de una formulacion para la manufactura de un medicamento de asma |
| ES2364636T3 (es) | 2001-12-19 | 2011-09-08 | Novartis Ag | Administración pulmonar de aminoglucósidos. |
| GB0207906D0 (en) | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
| ATE353231T1 (de) * | 2002-08-23 | 2007-02-15 | Schering Corp | Pharmazeutische zusammensetzungen |
| ATE384001T1 (de) * | 2002-08-27 | 2008-02-15 | Schering Corp | Verfahren zur herstellung von dosierinhalatorformulierungen |
| JP2007509147A (ja) * | 2003-10-20 | 2007-04-12 | シェーリング コーポレイション | 薬学的エアロゾル組成物 |
| EP1925293A3 (en) * | 2003-10-20 | 2010-01-13 | Schering Corporation | Pharmaceutical aerosol compositions |
| AU2007346134A1 (en) * | 2007-02-09 | 2008-08-14 | Merck Sharp & Dohme Corp. | Stable pharmaceutical drug aerosols |
| CN107951893B (zh) * | 2016-10-18 | 2022-04-26 | 天津金耀集团有限公司 | 一种糠酸莫米松粉吸入剂组合物 |
| CN107961217B (zh) * | 2016-10-18 | 2021-06-29 | 天津金耀集团有限公司 | 一种糠酸莫米松气雾剂组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5439670A (en) * | 1989-11-28 | 1995-08-08 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| HUT67449A (en) * | 1991-06-10 | 1995-04-28 | Schering Corp | Aerosol formulations containing 1,1,1,2,3,3,3-heptafluoropropane |
| CA2111003A1 (en) * | 1991-06-10 | 1992-12-23 | Julianne Fassberg | Non-chlorofluorocarbon aerosol formulations |
| PE44995A1 (es) * | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
-
1997
- 1997-08-26 DK DK97940582T patent/DK0927037T3/da active
- 1997-08-26 AT AT97940582T patent/ATE202936T1/de active
- 1997-08-26 WO PCT/US1997/014708 patent/WO1998008519A1/en not_active Ceased
- 1997-08-26 JP JP51173198A patent/JP3264496B2/ja not_active Expired - Lifetime
- 1997-08-26 CO CO97049283A patent/CO4900027A1/es unknown
- 1997-08-26 PL PL97331828A patent/PL189036B1/pl unknown
- 1997-08-26 AR ARP970103860A patent/AR008309A1/es active IP Right Grant
- 1997-08-26 IL IL12871497A patent/IL128714A/xx not_active IP Right Cessation
- 1997-08-26 MY MYPI97003925A patent/MY117377A/en unknown
- 1997-08-26 AU AU42329/97A patent/AU719079B2/en not_active Expired
- 1997-08-26 ID IDP972976A patent/ID18137A/id unknown
- 1997-08-26 PE PE1997000760A patent/PE100198A1/es not_active IP Right Cessation
- 1997-08-26 ZA ZA9707668A patent/ZA977668B/xx unknown
- 1997-08-26 CZ CZ1999632A patent/CZ294064B6/cs not_active IP Right Cessation
- 1997-08-26 KR KR1019997001588A patent/KR100316358B1/ko not_active Expired - Lifetime
- 1997-08-26 DE DE69705628T patent/DE69705628T2/de not_active Expired - Lifetime
- 1997-08-26 HU HU9902675A patent/HU227915B1/hu unknown
- 1997-08-26 TR TR1999/00379T patent/TR199900379T2/xx unknown
- 1997-08-26 SK SK253-99A patent/SK282147B6/sk not_active IP Right Cessation
- 1997-08-26 CN CNB97198980XA patent/CN1162157C/zh not_active Expired - Lifetime
- 1997-08-26 BR BR9711445A patent/BR9711445A/pt active Search and Examination
- 1997-08-26 EP EP97940582A patent/EP0927037B1/en not_active Expired - Lifetime
- 1997-08-26 NZ NZ334112A patent/NZ334112A/xx not_active IP Right Cessation
- 1997-08-26 SA SA97180339A patent/SA97180339B1/ar unknown
- 1997-08-26 CA CA002263905A patent/CA2263905C/en not_active Expired - Lifetime
- 1997-08-26 PT PT97940582T patent/PT927037E/pt unknown
- 1997-08-26 TW TW086112270A patent/TW475901B/zh not_active IP Right Cessation
- 1997-08-26 ES ES97940582T patent/ES2159148T3/es not_active Expired - Lifetime
-
1999
- 1999-02-26 NO NO19990956A patent/NO322528B1/no not_active IP Right Cessation
-
2001
- 2001-09-20 GR GR20010401531T patent/GR3036674T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |