[go: up one dir, main page]

LV12201B - USE OF NITROGEN OXIDE FOR BRONHOSTENOSE TREATMENT OR PROFILE - Google Patents

USE OF NITROGEN OXIDE FOR BRONHOSTENOSE TREATMENT OR PROFILE Download PDF

Info

Publication number
LV12201B
LV12201B LVP-98-169A LV980169A LV12201B LV 12201 B LV12201 B LV 12201B LV 980169 A LV980169 A LV 980169A LV 12201 B LV12201 B LV 12201B
Authority
LV
Latvia
Prior art keywords
pulmonary
ppm
gas
nitric oxide
treatment
Prior art date
Application number
LVP-98-169A
Other languages
English (en)
Latvian (lv)
Other versions
LV12201A (lv
Inventor
Warren M. Zapol
Claes Frostell
Original Assignee
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27089304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV12201(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The General Hospital Corporation filed Critical The General Hospital Corporation
Publication of LV12201A publication Critical patent/LV12201A/xx
Publication of LV12201B publication Critical patent/LV12201B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0266Nitrogen (N)
    • A61M2202/0275Nitric oxide [NO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Exhaust Gas Treatment By Means Of Catalyst (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LVP-98-169A 1990-12-05 1998-08-24 USE OF NITROGEN OXIDE FOR BRONHOSTENOSE TREATMENT OR PROFILE LV12201B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62286590A 1990-12-05 1990-12-05
US76723491A 1991-09-27 1991-09-27

Publications (2)

Publication Number Publication Date
LV12201A LV12201A (lv) 1999-01-20
LV12201B true LV12201B (en) 1999-05-20

Family

ID=27089304

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-98-169A LV12201B (en) 1990-12-05 1998-08-24 USE OF NITROGEN OXIDE FOR BRONHOSTENOSE TREATMENT OR PROFILE

Country Status (16)

Country Link
US (2) US5873359A (fr)
EP (4) EP0786264B1 (fr)
JP (3) JP2701978B2 (fr)
AT (3) ATE158509T1 (fr)
AU (1) AU657726B2 (fr)
CA (1) CA2097823C (fr)
DE (9) DE69133575T2 (fr)
DK (3) DK0786264T3 (fr)
EE (1) EE03119B1 (fr)
ES (3) ES2132043T3 (fr)
GR (3) GR960300032T1 (fr)
LU (3) LU90886I2 (fr)
LV (1) LV12201B (fr)
NL (3) NL300081I2 (fr)
SG (1) SG47527A1 (fr)
WO (1) WO1992010228A1 (fr)

Families Citing this family (283)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5570683A (en) * 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
DE69133575T2 (de) 1990-12-05 2008-04-17 The General Hospital Corp., Boston Verwendung von NO zur Behandlung der persistenten pulmonaren Hypertonie des Neugeborenen
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
US5380758A (en) * 1991-03-29 1995-01-10 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
AU651882B2 (en) * 1991-05-14 1994-08-04 Visiomed Group Limited Aerosol inhalation device
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
FR2695831B1 (fr) * 1992-09-24 1994-11-10 Air Liquide Installation et procédé de fourniture d'un mélange gazeux aux voies respiratoires d'un utilisateur.
US5427797A (en) * 1993-04-06 1995-06-27 Brigham And Women's Hospital Systemic effects of nitric oxide inhalation
EP0692990B1 (fr) * 1993-04-06 1998-09-23 Minnesota Mining And Manufacturing Company Desagglomerants pour inhalateurs a poudre seche
DE59409834D1 (de) * 1993-04-17 2001-09-27 Messer Griesheim Austria Ges M Gerät zur kontrollierten Zudosierung von NO zur Atemluft von Patienten
ES2147236T3 (es) * 1993-07-06 2000-09-01 Aerocrine Ab Un sistema para ser utilizado para la determinacion de niveles no en el aire exhalado y metodos de diagnostico para los trastornos relacionados con niveles anormales de no.
SE9302478L (sv) * 1993-07-22 1994-11-07 Siemens Elema Ab Gasblandning och apparat för att tillföra gasblandningen till lungorna hos ett levande väsen
DE4327731C1 (de) * 1993-08-18 1994-11-10 Messer Griesheim Gmbh NO-haltiges Gasgemisch zur Behandlung pulmonaler Erkrankungen
DE4327732C1 (de) * 1993-08-18 1994-09-01 Messer Griesheim Gmbh NO-haltiges Gasgemisch zur Behandlung pulmonaler Erkrankungen
GB9320978D0 (en) * 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
US5558083A (en) * 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
CA2189351C (fr) * 1994-05-13 2008-12-30 Stephen J. Farr Formulation en aerosol contenant un narcotique
DE4419860A1 (de) * 1994-06-07 1995-12-14 Hoechst Ag Verfahren und Filter zur Herstellung von NO¶2¶-freiem Stickstoffmonoxid mit schwefelhaltigen Polymeren
US5615669A (en) * 1994-07-22 1997-04-01 Siemens Elema Ab Gas mixture and device for delivering the gas mixture to the lungs of a respiratory subject
US6063407A (en) * 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5665077A (en) * 1995-04-24 1997-09-09 Nitrosci Pharmaceuticals Llc Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
SE506208C2 (sv) 1995-07-05 1997-11-24 Aerocrine Systems Kb Anordning för uppsamling av gas från de övre luftvägarna och leverans av denna gas till inandningsluften i en respirator
RU2072241C1 (ru) * 1995-09-20 1997-01-27 Панина Елена Владимировна Способ формирования дыхательной газовой смеси и аппарат для его осуществления
EP0768095B1 (fr) * 1995-10-13 2001-12-19 Siemens-Elema AB Tube trachéal et dispositif pour système de ventilation artificielle
DE69617719D1 (de) * 1995-10-20 2002-01-17 Air Liquide Pharmazeutische zusammensetzung von stickstoffmonoxid
WO1997018000A1 (fr) * 1995-11-13 1997-05-22 Brigham And Women's Hospital S-nitroso-hemoglobine et ses utilisations therapeutiques
US5699790A (en) * 1996-03-21 1997-12-23 Ohmeda Inc. System for predicting NO2 concentrations
EP0914103B1 (fr) * 1996-04-05 2006-06-28 The General Hospital Corporation Traitement d'un type d'hemoglobinose
US5765548A (en) * 1996-05-07 1998-06-16 Perry; Bryan J. Use of nitric oxide in the treatment of exercised induced pulmonary hemorrhaging in equine
US5811437A (en) * 1996-05-21 1998-09-22 Eli Lilly And Company Methods of increasing nitric oxide synthesis
CA2206477A1 (fr) 1996-07-10 1998-01-10 Ohmeda Inc. Systeme de correction d'un moniteur de no2
US5732694A (en) * 1996-12-13 1998-03-31 Ohmeda Inc. System for correcting NO2 monitor
WO1998002170A1 (fr) * 1996-07-17 1998-01-22 The General Hospital Corporation Procede servant a provoquer la vasodilatation et a traiter l'hypertension pulmonaire au moyen du transfert provoque par adenovirus du gene de synthase d'oxyde nitrique
US6720309B1 (en) * 1996-07-17 2004-04-13 Leuven Research And Development, V.Z.W. Method of inducing vasodilation and treating pulmonary hypertension using adenoviral-mediated transfer of the nitric oxide synthase gene
JP3880103B2 (ja) * 1996-07-18 2007-02-14 住友精化株式会社 医療用一酸化窒素混合ガスおよびその製造方法
SE506778C2 (sv) * 1996-08-12 1998-02-09 Siemens Elema Ab Förfarande vid blandning av gaser och en anordning för blandning av gaser
AU3901497A (en) * 1996-08-13 1998-03-06 University Of Massachusetts Nitric oxide sensor
DE19734279A1 (de) * 1997-08-07 1999-02-11 Messer Griesheim Gmbh Wasserstoffhaltiges Medikament
US5732693A (en) 1996-10-02 1998-03-31 Ohmeda Inc. Pause control of nitric oxide therapy
DK0973443T3 (da) 1997-01-17 2006-07-24 Ino Therapeutics Gmbh Styret gasforsyningssystem
US6027713A (en) * 1997-03-06 2000-02-22 Meri Charmyne Russell Composition and method for the treatment of exercise induced pulmonary hemorrhage
SE9700940D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler IV
CA2225013C (fr) 1997-04-04 2006-06-06 Institut Du N.O. Inc. Systeme d'injection pour l'administration d'une substance gazeuse
WO1998046277A2 (fr) * 1997-04-16 1998-10-22 Ohmeda, Inc. Compensation de l'humidite pour l'etalonnage a zero des cellules electrochimiques dans des dispositifs de mesure de gaz respiratoire
US5918596A (en) * 1997-04-22 1999-07-06 Instrumentarium Corp. Special gas dose delivery apparatus for respiration equipment
FR2762992B1 (fr) * 1997-05-07 2000-08-25 Air Liquide Transporteurs de no a base de complexes polyazamacrocycles de fer et de cobalt
US6125846A (en) * 1997-05-16 2000-10-03 Datex-Ohmeda, Inc. Purge system for nitric oxide administration apparatus
US6656452B1 (en) * 1997-10-21 2003-12-02 The General Hospital Corporation Use of inhaled NO as anti-inflammatory agent
US6109260A (en) * 1998-02-18 2000-08-29 Datex-Ohmeda, Inc. Nitric oxide administration device with timed pulse
US6142147A (en) * 1998-03-31 2000-11-07 The General Hospital Corporation Nasal delivery system for inhaled nitric oxide
US20070086954A1 (en) * 1998-11-23 2007-04-19 Miller Christopher C Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
CA2254645A1 (fr) * 1998-11-23 2000-05-23 Pulmonox Medical Corporation Methode et appareil pour traiter les infections respiratoires par l'inhalation d'oxyde nitrique
JP3641151B2 (ja) * 1999-02-04 2005-04-20 帝人株式会社 治療用ガス投入用呼吸マスク
US6346382B1 (en) * 1999-06-01 2002-02-12 Vanderbilt University Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
US9486429B2 (en) * 1999-06-01 2016-11-08 Vanderbilt University Therapeutic methods employing nitric oxide precursors
FR2795644B1 (fr) * 1999-07-02 2004-07-30 Air Liquide Sante Int Utilisations therapeutiques d'un melange helium/oxygene, en particulier dans le traitement de l'asthme
EP1218049B1 (fr) * 1999-07-12 2006-09-20 Capnia Incorporated Dispositif pour soulager les cephalees, les rhinites et d'autres affections communes
ATE456056T1 (de) * 1999-08-02 2010-02-15 Univ Duke Methode zur bestimmung der physiologischen wirkungen von hämoglobin
US6314956B1 (en) 1999-09-08 2001-11-13 Duke University Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders
US7045152B2 (en) * 1999-09-08 2006-05-16 Duke University Treating pulmonary disorders with gaseous agent causing repletion of GSNO
US6694969B1 (en) 1999-09-22 2004-02-24 Instrumentarium Corp. Method to improve oxygenation in subjects suffering impaired oxygenation
WO2001021239A1 (fr) 1999-09-22 2001-03-29 Instrumentarium Corporation Procede d'amelioration de l'oxygenation chez des sujets souffrant d'oxygenation deficiente
US6612306B1 (en) 1999-10-13 2003-09-02 Healthetech, Inc. Respiratory nitric oxide meter
DE60024855T2 (de) 1999-10-29 2006-08-31 Orion Corp. Verwendung eines imidazolderivats zur behandlung oder verhütung von hypotension und schock
SE9903985D0 (sv) * 1999-11-03 1999-11-03 Aga Ab Use of nitric oxide
DE60027921D1 (de) * 1999-11-08 2006-06-14 Capnia Inc Vorrichtung zur gleichzeitigen verabreichung von gasen und medikamenten
US20070039615A1 (en) * 1999-11-08 2007-02-22 Capnia, Incorporated Methods and apparatus for treating rhinitis
US20060172017A1 (en) 1999-11-08 2006-08-03 Capnia, Incorporated Methods and apparatus for the enhanced delivery of physiologic agents to tissue surfaces
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6581599B1 (en) * 1999-11-24 2003-06-24 Sensormedics Corporation Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients
US6758214B2 (en) 2000-01-28 2004-07-06 Cyterra Corporation Simple nitric oxide generator for ambulatory and/or bedside inhaled no treatment
WO2001078735A1 (fr) * 2000-04-13 2001-10-25 Innovata Biomed Limited Medicaments contenant du formoterol et de la fluticasone, destines au traitement de troubles respiratoires
US6601580B1 (en) * 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation
US6951215B1 (en) * 2000-07-14 2005-10-04 Tufts University Drug delivery device for animals
DE60136366D1 (de) 2000-08-11 2008-12-11 David R Whitlock Ammoniak-oxidierende bakterien enthaltende zusammensetzungen zur steigerung der stickoxidproduktion, stickoxid-vorläufer und verfahren zu deren verwendung
AU2001296456A1 (en) 2000-09-29 2002-04-08 Healthetech, Inc. Indirect calorimetry system
US6668828B1 (en) 2000-10-16 2003-12-30 Pulmonox Technologies Corporations System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient
SE0004229D0 (sv) * 2000-11-17 2000-11-17 Aga Ab Inhalation of nitric oxide
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7335181B2 (en) * 2000-12-26 2008-02-26 Pulmonox Technologies Corporation Nitric oxide decontamination of the upper respiratory tract
AUPR315401A0 (en) 2001-02-16 2001-03-15 Resmed Limited An apparatus for supplying clean breathable gas
WO2002087673A1 (fr) * 2001-04-25 2002-11-07 Messer Austria Gmbh Appareil de dosage d'aerosol
US6749834B2 (en) * 2001-06-19 2004-06-15 World Precision Instruments, Inc. Methods and apparatus for therapeutic treatment of respiratory, cardiac and other pathologies
WO2003020211A2 (fr) * 2001-09-05 2003-03-13 Cyterra Corporation Generation d'oxyde nitrique
US6575918B2 (en) 2001-09-27 2003-06-10 Charlotte-Mecklenburg Hospital Non-invasive device and method for the diagnosis of pulmonary vascular occlusions
US20030070674A1 (en) * 2001-10-12 2003-04-17 Bryan Perry Use of aerosolized compounds in the treatment of exercise induced pulmonary hemorrhage in an equine
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US6627602B2 (en) * 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
US6472390B1 (en) * 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure
US20040110691A1 (en) * 2001-11-13 2004-06-10 Stamler Jonathan S. Thiol reactive agents as a therapeutic modality
KR20040086267A (ko) * 2002-01-11 2004-10-08 데이비드 알. 휘트록 암모니아 산화 박테리아를 포함하는 조성물 및 그를사용하는 방법
US20030170223A1 (en) * 2002-02-01 2003-09-11 Board Of Trustees Of Michigan State University Pulmonary vasodilator surfactant compositions and method of use
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
EP1514103A4 (fr) * 2002-05-29 2006-05-24 Univ Duke Mesure du monoxyde d'azote dans des gaz hemotoxiques, et traitement fonde sur cette mesure
PL375161A1 (en) * 2002-06-21 2005-11-28 University Of Pittsburgh Of The Commonwealth System Of Higher Education Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
EP3335752A1 (fr) * 2002-06-28 2018-06-20 The Research Foundation of the State University of New York Dispositif et procédé d'administration d'agent thérapeutique
AU2003259897B2 (en) * 2002-08-20 2008-04-03 Aga Ab Methods and devices for administration of therapeutic gases
US7337776B2 (en) * 2002-08-20 2008-03-04 Aga Ab Methods for easing pain and anxiety from atrial or ventricular defibrillation
US7681572B2 (en) * 2002-08-20 2010-03-23 Aga Ab Method and devices for administration of therapeutic gases
US8001962B2 (en) * 2002-08-23 2011-08-23 Sheiman Ultrasonic Research Foundation Pty Ltd. Nebulizing and drug delivery device
US6869402B2 (en) * 2002-08-27 2005-03-22 Precision Pulsus, Inc. Method and apparatus for measuring pulsus paradoxus
US7828739B2 (en) * 2002-08-27 2010-11-09 Precision Pulsus, Inc. Apnea detection system
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
EP1563845A4 (fr) * 2002-10-10 2008-02-20 Univ Kyoto Remedes pour affections allergiques
CA2413834A1 (fr) 2002-12-10 2004-06-10 1017975 Alberta Limited Generateur de monoxyde d'azote gazeux
US9138707B2 (en) 2002-12-10 2015-09-22 Sy Kimball Portable, nitric oxide generator
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
US20040265238A1 (en) * 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
US9675637B2 (en) 2003-07-09 2017-06-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
US20070148136A1 (en) * 2003-09-26 2007-06-28 Whitlock David R Methods of using ammonia oxidizing bacteria
US7552731B2 (en) * 2003-11-14 2009-06-30 Remcore, Inc. Remote control gas regulation system
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas
US20050191245A1 (en) * 2004-02-27 2005-09-01 Adams Christopher P. Nasal administration of calcium channel, blockers for treatment of hypertension and other cardiovascular disorders
WO2005084301A2 (fr) * 2004-03-01 2005-09-15 Lumen Therapeutics, Llc Compositions et methodes de traitement de maladies
JP2008500965A (ja) * 2004-03-17 2008-01-17 エムペックス・ファーマシューティカルズ・インコーポレーテッド 細菌の排出ポンプ阻害剤の使用および投与
US7994225B2 (en) * 2004-03-17 2011-08-09 Rempex Pharmaceuticals, Inc. Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections
EP1755715A4 (fr) 2004-05-11 2010-03-24 Sensormedics Corp Dosage intermittent d'oxyde nitrique gazeux
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
JP5421530B2 (ja) * 2004-08-18 2014-02-19 ゲノ エルエルシー 二酸化窒素(no2)の酸化窒素(no)への変換
US7618594B2 (en) * 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
US8056557B2 (en) * 2005-03-09 2011-11-15 Ric Investments, Llc Nebulizing drug delivery device with barrier
US7721729B2 (en) * 2005-03-09 2010-05-25 Ric Investments, Llc Nebulizing drug delivery device for ventilator
US7814901B2 (en) * 2005-03-09 2010-10-19 Ric Investments, Llc Nebulizing drug delivery device with increased flow rate
US7631643B2 (en) 2005-03-09 2009-12-15 Ric Investments, Llc Nebulizing drug delivery device with interlock detection and temperature protection
US8557300B2 (en) * 2005-05-19 2013-10-15 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
ATE516086T1 (de) * 2005-05-23 2011-07-15 Biosonic Australia Pty Ltd Vorrichtung zur zerstäubung und flüssigkeitsfiltration
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
US7523752B2 (en) * 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US7566308B2 (en) * 2005-10-13 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for pulmonary artery pressure signal isolation
US20070116785A1 (en) * 2005-11-18 2007-05-24 Miller Christopher C Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
CA2633099C (fr) * 2005-12-21 2015-04-21 Uti Limited Partnership Traitement de maladies respiratoires
US8790715B2 (en) * 2006-02-16 2014-07-29 Ino Therapeutics Llc Method and apparatus for generating nitric oxide for medical use
US20100313883A1 (en) * 2006-04-20 2010-12-16 Koninklijke Philips Electronics N.V. Ultrasonic bebulilzer with metal coated ultrasonic genrator
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
EP1903003B1 (fr) * 2006-07-05 2017-07-05 BSN medical GmbH Procede de production photolytique de monoxyde d'azote
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
EP2099463B1 (fr) * 2006-11-07 2014-07-16 The General Hospital Corporation Atténuation de la vasoconstriction induite par un transporteur d'oxygène vasoactif
US20100143503A1 (en) * 2006-12-22 2010-06-10 Ikaria, Inc. Combinations of nitric oxide and sulfide and methods of use and manufacture thereof
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US8176915B2 (en) * 2007-03-15 2012-05-15 Koninklijke Philips Electronics N.V. End-tidal gas estimation system and method
US8166971B2 (en) * 2007-03-15 2012-05-01 Ric Investments, Llc End-tidal gas estimation system and method
WO2008118360A1 (fr) * 2007-03-23 2008-10-02 Geno Llc Conversion du dioxyde d'azote (no2) en oxyde nitrique (no)
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
WO2009048521A1 (fr) * 2007-10-11 2009-04-16 Duke University Potentialisation de l'effet d'un composé contenant de l'oxyde nitrique
EP2230934B8 (fr) 2007-12-14 2012-10-24 AeroDesigns, Inc Administration de produits alimentaires sous forme d'aérosols
JP2011507968A (ja) * 2007-12-27 2011-03-10 エイヤーズ ファーマシューティカルズ、インク. エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用
CA2713049C (fr) 2008-01-28 2017-02-28 Geno Llc Conversion de dioxyde d'azote (no<sb>2</sb>) en monoxyde d'azote (no)
US20090312423A1 (en) * 2008-01-31 2009-12-17 Vanderbilt University Therapeutic treatment for lung conditions
US9649467B2 (en) 2008-01-31 2017-05-16 Syk Technologies, Llc Nitric oxide reactor and distributor apparatus and method
US8434475B2 (en) 2008-01-31 2013-05-07 Genosys, Inc. Nitric oxide reactor and distributor apparatus and method
US8720436B2 (en) * 2008-01-31 2014-05-13 Genosys, Inc. Nitric oxide gel apparatus and method
PT2240170T (pt) 2008-01-31 2019-06-24 Univ Vanderbilt Métodos e composições para o tratamento de hemorragia subaracnóidea aneurismática coronária e arterial
US8501090B2 (en) * 2008-03-24 2013-08-06 Christian S. Minton Anti-microbial gas apparatus and method
US20100040703A1 (en) * 2008-08-13 2010-02-18 Chris Miller Use of nitric oxide
US10780241B2 (en) 2008-08-21 2020-09-22 Vero Biotech LLC Devices and methods for minimizing and treating high-altitude sickness
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
GB2463883A (en) * 2008-09-25 2010-03-31 Pharma Patents Ltd A pharmaceutical composition comprising an A-SMase inhibitor and an NO-donor
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
NZ596976A (en) * 2009-05-15 2014-05-30 Recro Pharma Inc Sublingual dexmedetomidine compositions and methods of use thereof
HRP20171020T1 (hr) 2009-05-27 2017-10-06 Ino Therapeutics Llc Uređaj za aktivranje indeksiranog ventila i sklop spremnika pod tlakom s ovratnikom
US8613958B2 (en) 2009-06-22 2013-12-24 Geno Llc Nitric oxide therapies
AU2009202685B1 (en) 2009-06-30 2010-08-19 Ino Therapeutics Llc Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
RU2420321C2 (ru) * 2009-08-11 2011-06-10 Анищенко Сергей Викторович Кислородная газожидкостная смесь (варианты)
CA2781295C (fr) * 2009-11-20 2018-02-13 Geno Llc Systeme de distribution d'oxyde nitrique
EP2563435B1 (fr) 2010-04-26 2020-06-03 VERO Biotech LLC Administration de monoxyde d'azote (no) ultra pur
DE102010016699A1 (de) 2010-04-29 2011-11-03 Maquet Gmbh & Co. Kg Verfahren und Vorrichtung zur Applikation mindestens eines medizinischen Gases an einen mit Hilfe eines Beatmungsgeräts beatmeten Patienten
US8685467B2 (en) 2010-08-03 2014-04-01 J. W. Randolph Miller Nitric oxide generation, dilution, and topical application apparatus and method
PL3479863T3 (pl) * 2010-09-10 2022-05-30 Mallinckrodt Pharmaceuticals Ireland Limited Kompozycje, sposoby i wyroby dotyczące farmaceutycznego tlenku azotu i układów kontrolowanego dostarczania go pacjentowi
WO2012037665A1 (fr) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Oxyde nitrique libérant un ester d'acide aminé pour le traitement de l'hypertension pulmonaire et autres états respiratoires
EP2646365B1 (fr) 2010-12-03 2016-08-03 Koninklijke Philips N.V. Procédé et dispositif de production d'oxyde nitrique
NO2661300T3 (fr) 2011-01-06 2018-03-03
US10853819B2 (en) * 2011-04-14 2020-12-01 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US10445846B2 (en) * 2011-04-14 2019-10-15 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
FR2976260B1 (fr) 2011-06-09 2013-07-05 Air Liquide Procede de conditionnement de melanges no/n2 avec etapes de purge et rincage gazeux prealable
CN103796704B (zh) 2011-07-12 2016-12-07 博讯瓦勒公司 用于将抗微生物剂递送到经皮导管中的装置
CA3003708C (fr) 2011-10-03 2019-01-15 NitricGen, Inc. Appareil et methode de production d'oxyde nitrique en quantites controlees et precises
US9572833B2 (en) 2011-11-07 2017-02-21 The General Hospital Corporation Treatment of red blood cells
SG11201403094TA (en) 2011-12-11 2014-10-30 Recro Pharma Inc Intranasal dexmedetomidine compositions and methods of use thereof
US20150174158A1 (en) 2012-03-07 2015-06-25 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
CN104411317A (zh) 2012-03-15 2015-03-11 Ino治疗有限责任公司 用于施用高浓度一氧化碳的方法
FR2991025B1 (fr) 2012-05-24 2014-07-04 Air Liquide Sante Int Conditionnement d'un melange gazeux no/azote a haute concentration en no
FR2991026B1 (fr) 2012-05-24 2014-07-04 Air Liquide Sante Int Conditionnement a haute pression d'un melange gazeux no/azote
FR2990858B1 (fr) 2012-05-24 2015-04-03 Air Liquide Sante Int Melange gazeux no/azote a teneur elevee en no pour traiter les detresses respiratoires hypoxemiantes severes
MX376042B (es) 2012-12-04 2025-03-07 Mallinckrodt Hospital Products Ip Ltd Canula para minimizar la disolucion de la dosificacion durante la administracion de oxido nitrico
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
EP2961479A4 (fr) 2013-02-28 2017-07-05 Aires Pharmaceuticals, Inc. Nitrite inorganique pour améliorer l'hémodynamique cardiopulmonaire
ES2733343T3 (es) 2013-03-15 2019-11-28 Massachusetts Gen Hospital Síntesis de óxido nítrico gaseoso para inhalación
CN105283213B (zh) 2013-03-15 2018-10-16 通用医疗公司 一氧化氮的吸气合成
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
WO2014210030A2 (fr) 2013-06-25 2014-12-31 Ino Therapeutics Llc Procédés de réduction du risque de mortalité iatrogène
US9492626B2 (en) 2013-06-28 2016-11-15 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Breathing assistance assemblies suitable for long term no therapy
US9522248B2 (en) 2013-06-28 2016-12-20 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Breathing assistance apparatus for delivery of nitric oxide to a patient by means of a nasal cannula assembly with flow control passage
US9522247B2 (en) 2013-06-28 2016-12-20 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Method of treating a patient having pulmonary hypertension by long term NO therapy
US9566407B2 (en) 2013-06-28 2017-02-14 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Nasal cannula assembly with flow control passage communicating with a deformable reservoir
US9486600B2 (en) 2013-06-28 2016-11-08 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Nasal cannula assembly with inhalation valves communicating with a deformable reservoir
US9517318B2 (en) 2013-06-28 2016-12-13 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Method of delivering medical gases via a nasal cannula assembly with flow control passage communicating with a deformable reservoir
US10183039B2 (en) 2013-07-15 2019-01-22 Vanderbilt University Methods for the production of collagen IV
FR3015000B1 (fr) 2013-12-12 2016-05-27 Air Liquide Sante (International) Systeme de stockage et de distribution de melanges no/azote
CA2938996A1 (fr) 2014-02-10 2015-08-13 Patara Pharma, LLC Methodes de traitement de maladies pulmonaires au moyen de stabilisateurs de mastocyte
PT3104853T (pt) 2014-02-10 2020-01-14 Respivant Sciences Gmbh Tratamento com estabilizadores de mastócitos para distúrbios sistémicos
EP3129092A4 (fr) * 2014-04-09 2017-12-27 12th Man Technologies, Inc. Systèmes et procédés de distribution d'oxyde nitrique en concentration élevée
US11225640B2 (en) 2014-04-15 2022-01-18 Aobiome Llc Ammonia oxidizing bacteria for treatment of psoriasis
CN106456678A (zh) 2014-04-15 2017-02-22 Ao生物医学有限责任公司 氨氧化型亚硝化单胞菌菌株d23
EP2937089A1 (fr) 2014-04-23 2015-10-28 Linde AG Dispositif pour le traitement de, le traitement de complications résultant de, et/ou la prévention de troubles respiratoires
ES2755352T3 (es) 2014-05-02 2020-04-22 Excelsior Medical Corp Paquete en tira para tapón antiséptico
RU2730960C2 (ru) 2014-10-20 2020-08-26 Зе Дженерал Хоспитал Корпорэйшн Системы и способы синтеза оксида азота
US10213572B2 (en) 2014-10-20 2019-02-26 Vero Biotech LLC Nitrogen dioxide storage cassette
CN111603643B (zh) 2015-04-02 2023-05-23 希尔-罗姆服务私人有限公司 呼吸装置的压力控制
AU2016262400B2 (en) 2015-05-08 2021-01-21 Icu Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
EP3331522A1 (fr) 2015-08-07 2018-06-13 Patara Pharma LLC Méthodes de traitement de troubles liés aux mastocytes par des stabilisateurs de mastocytes
US10265296B2 (en) 2015-08-07 2019-04-23 Respivant Sciences Gmbh Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
US20180243526A1 (en) * 2015-09-09 2018-08-30 Advanced Inhalation Therapies (AIT), Ltd. Nitric oxide inhalation therapy for infants with bronchiolitis
US9744190B2 (en) 2016-01-15 2017-08-29 Thomas Tait Continuous gas generator
US10052348B2 (en) 2016-01-27 2018-08-21 Syk Technologies, Llc Nitric oxide topical application apparatus and methods
JP2019513691A (ja) * 2016-02-12 2019-05-30 マリンクロット ホスピタル プロダクツ アイピー リミテッド 吸入用一酸化窒素の左心補助人工心臓への使用とモニタリング
BR112018069582A2 (pt) 2016-03-25 2019-01-22 Massachusetts Gen Hospital sistemas e métodos de entrega para síntese elétrica de plasma de óxido nítrico
JP2019528320A (ja) 2016-08-31 2019-10-10 レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh 特発性肺線維症による慢性咳の治療のためのクロモリン組成物
EP3522983A4 (fr) 2016-10-07 2020-06-03 Respivant Sciences GmbH Compositions à base de cromolyne pour le traitement d'une fibrose pulmonaire
PL3525865T3 (pl) 2016-10-14 2023-02-06 Icu Medical, Inc. Nasadki dezynfekcyjne dla łączników medycznych
BR112019016837B1 (pt) 2017-02-27 2024-03-12 Third Pole, Inc Sistemas portáteis de geração de óxido nítrico, (no)
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
RU2020110925A (ru) 2017-02-27 2020-12-15 Серд Поул, Инк. Системы и способы получения оксида азота
MX2019011432A (es) 2017-03-31 2020-01-20 Massachusetts Gen Hospital Sistemas y metodos para un generador de oxido nitrico enfriado.
WO2018204206A2 (fr) 2017-05-01 2018-11-08 Icu Medical, Inc. Raccords de fluide médical et procédés pour fournir des additifs dans des conduites de fluide médical
AU2018358349A1 (en) * 2017-11-02 2020-05-28 Beyond Air, Inc. Inhalation of nitric oxide
JP6618976B2 (ja) * 2017-11-14 2019-12-11 イノ セラピューティクス エルエルシー 指標付弁と襟部を有する加圧容器組立体を係合するため、かつ薬物送達を調整するための装置と流体連通したプランジャ組立体により直線的に作動させるための装置および方法
WO2020074957A1 (fr) * 2018-10-12 2020-04-16 Sanotize Research And Development Corp. Compositions à dégagement de gaz et systèmes de récipient et de distribution
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
EP3883638A1 (fr) 2018-11-21 2021-09-29 ICU Medical, Inc. Dispositif antimicrobien comprenant un capuchon avec bague et insert
JP7111404B2 (ja) * 2019-04-19 2022-08-02 国立研究開発法人物質・材料研究機構 窒素系ガス徐放剤及びこれで構成された窒素系ガス徐放体、並びに該徐放体を用いた窒素系ガスの徐放方法、呼吸器具、包装体及び徐放装置
JP2022532654A (ja) 2019-05-15 2022-07-15 サード ポール,インコーポレイテッド 一酸化窒素を生成するシステム及び方法
WO2020232397A1 (fr) 2019-05-15 2020-11-19 Third Pole, Inc. Électrodes pour la génération d'oxyde nitrique
FR3103110B1 (fr) 2019-11-15 2021-10-08 Air Liquide Dispositif de fourniture de gaz thérapeutique, en particulier de NO ou de N2O, à un patient
BR112022010072A2 (pt) 2019-11-25 2022-08-30 Beyond Air Inc Métodos que empregam óxido nítrico gasoso para inibir crescimento de tumor
US11872367B2 (en) * 2020-01-02 2024-01-16 Becton, Dickinson And Company Antimicrobial and antithrombogenic gaseous release device and related systems and methods
US11691879B2 (en) 2020-01-11 2023-07-04 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US12459820B2 (en) 2020-06-11 2025-11-04 J. W. Randolph Miller Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy
WO2021258025A1 (fr) 2020-06-18 2021-12-23 Third Pole, Inc. Systèmes et procédés de prévention et de traitement d'infections avec de l'oxyde nitrique
US12156886B2 (en) * 2020-11-12 2024-12-03 Thermolife International, Llc Methods of increasing blood oxygen saturation
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches
EP4255552A1 (fr) 2020-12-07 2023-10-11 ICU Medical, Inc. Capuchons, systèmes et procédés de dialyse péritonéale
IL304991A (en) 2021-02-11 2023-10-01 Thermolife Int Llc A method of administering nitrous oxide gas
WO2023049873A1 (fr) 2021-09-23 2023-03-30 Third Pole, Inc. Systèmes et procédés destinés à fournir de l'oxyde nitrique
FR3127408B1 (fr) 2021-09-29 2024-05-10 Inosystems Chariot hospitalier de transport de bouteille de gaz, notamment de NO médical
FR3131538B1 (fr) 2022-01-05 2025-01-17 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence
EP4209243B1 (fr) 2022-01-05 2024-08-14 Inosystems Dispositif de délivrance de no avec système de dosage d'urgence
FR3137841B1 (fr) 2022-07-18 2024-06-14 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence
FR3132025B1 (fr) 2022-01-24 2025-06-27 Inosystems Cartouche de stockage d’un mélange NO/azote et installation de fourniture de gaz associée
FR3133316B1 (fr) 2022-03-09 2024-04-12 Inosystems Dispositif de délivrance de NO avec circuit de secours
FR3133317B1 (fr) 2022-03-09 2024-03-01 Inosystems Appareil de délivrance de NO avec système de ventilation manuelle
FR3133318B1 (fr) 2022-03-09 2024-03-22 Inosystems Dispositif de délivrance de NO avec circuit de secours à débit contrôlé
FR3133315B1 (fr) 2022-03-09 2024-03-22 Inosystems Appareil de délivrance de NO à deux sorties de gaz
FR3136986B1 (fr) 2022-06-24 2024-06-14 Inosystems Affichage de la dose de NO par un dispositif de fourniture de NO en phase de pause
FR3138773B1 (fr) 2022-08-11 2024-08-02 Inosystems Installation de fourniture de gaz comprenant un ventilateur médical et un dispositif de délivrance de NO avec un système de dosage d’urgence
FR3145873A1 (fr) 2023-02-20 2024-08-23 Inosystems Appareil de fourniture de gaz, tel du NO, à un patient avec comptage du temps total de traitement effectif
FR3146810B1 (fr) 2023-03-21 2025-04-04 Inosystems Dispositif de calibration des capteurs d’un appareil de délivrance de NO
FR3148373A1 (fr) 2023-05-04 2024-11-08 Inosystems Appareil de délivrance de monoxyde d’azote gazeux en mode pulsé
FR3148527B1 (fr) 2023-05-12 2025-10-03 Inosystems Chariot hospitalier de transport de bouteille de gaz à sangles de fixation semi-rigides
FR3148723A1 (fr) 2023-05-16 2024-11-22 Inosystems Appareil de délivrance de NO à capteurs MOS à longue durée de vie
FR3150441A1 (fr) 2023-06-29 2025-01-03 Inosystems Affichage d’un rappel de maintenance sur un appareil de fourniture de monoxyde d’azote médical
FR3151765B1 (fr) 2023-08-02 2025-08-01 Inosystems Installation d’administration de NO gazeux comprenant un ventilateur médical à humidificateur intégré
FR3154010A1 (fr) 2023-10-11 2025-04-18 Inosystems Appareil de délivrance de NO comprenant une ligne d’analyse à pompe piézoélectrique
FR3154009A1 (fr) 2023-10-12 2025-04-18 Inosystems Affichage d’une dose de NO préfixée sur un appareil de fourniture de gaz médical
FR3154008A1 (fr) 2023-10-12 2025-04-18 Inosystems Alerte d’inversion de sens de connexion du capteur de débit d’une installation d’administration de monoxyde d’azote
FR3157812A1 (fr) 2024-01-03 2025-07-04 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence
FR3157813A1 (fr) 2024-01-03 2025-07-04 Inosystems Installation et méthode de titration de NO
FR3158448A1 (fr) 2024-01-19 2025-07-25 Inosystems Système de suivi à distance d’un appareil de fourniture de monoxyde d’azote
FR3159526A1 (fr) 2024-02-23 2025-08-29 Inosystems Installation de fourniture de NO pour fournir un débit de secours en cas de dysfonctionnement du capteur de débit
FR3160895A1 (fr) 2024-04-04 2025-10-10 Inosystems Appareil de fourniture de NO avec modification automatique des alarmes lors des changements de dose
FR3160894A1 (fr) 2024-04-04 2025-10-10 Inosystems Appareil de fourniture de NO avec fixation automatique des seuils d’alarme
FR3161571A1 (fr) 2024-04-24 2025-10-31 Inosystems Appareil de délivrance de NO alimenté par deux bouteilles de gaz
FR3162006A1 (fr) 2024-05-13 2025-11-14 Inosystems Appareil de fourniture de NO adapté au transport terrestre ou aérien

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3367332A (en) * 1965-08-27 1968-02-06 Gen Electric Product and process for establishing a sterile area of skin
US3785377A (en) * 1970-11-12 1974-01-15 S Jorgensen Plant, preferably for anaesthesia
US3745991A (en) * 1971-02-22 1973-07-17 Champion Spark Plug Co Environmental contamination control device
US4010897A (en) * 1976-03-31 1977-03-08 Charles F. Kettering Foundation Method and apparatus for home production and application of nitrogen fertilizer
IL57239A (en) * 1979-05-08 1982-04-30 Alamaro Moshe Production of nitric oxides
US4297123A (en) * 1980-02-07 1981-10-27 Wyse Harold G Method and apparatus for producing a nitrate fertilizer
US4336798A (en) * 1980-10-06 1982-06-29 Anthony V. Beran Medical corrugated respiratory tube
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
US4592348A (en) * 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
US4675174A (en) * 1985-08-16 1987-06-23 Alza Corporation Veterinary dispenser delivering beneficial agent by gas power generated in situ
US4852561A (en) * 1988-07-27 1989-08-01 Sperry C R Inhalation device
US4877589A (en) * 1988-09-19 1989-10-31 Hare Louis R O Nitrogen fixation by electric arc and catalyst
US4915915A (en) * 1988-10-11 1990-04-10 Treharne Richard W Water-powdered piezoelectric unit for producing nitrogen fertilizer
US4954526A (en) * 1989-02-28 1990-09-04 The United States Of America As Represented By The Department Of Health And Human Services Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
US5208233A (en) * 1989-09-15 1993-05-04 The United States Of America As Represented By The Department Of Health And Human Services Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
US5007419A (en) * 1989-09-25 1991-04-16 Allan Weinstein Inhaler device
US5178138A (en) * 1990-09-11 1993-01-12 Walstrom Dennis R Drug delivery device
US5155137A (en) * 1990-09-20 1992-10-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complexes of nitric oxide with polyamines
US5187305A (en) * 1990-11-26 1993-02-16 Glaxo Inc. S-nitroso-N-alkonoylpenicillamines
US5396882A (en) * 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
DE69133575T2 (de) 1990-12-05 2008-04-17 The General Hospital Corp., Boston Verwendung von NO zur Behandlung der persistenten pulmonaren Hypertonie des Neugeborenen
IL101406A (en) * 1991-03-29 1998-02-08 Brigham & Womens Hospital Pharmaceutical compositions containing s-nitrosothiol derivatives
US5385937A (en) * 1991-04-10 1995-01-31 Brigham & Women's Hospital Nitrosation of homocysteine as a method for treating homocysteinemia
WO1993012068A1 (fr) * 1991-12-11 1993-06-24 Brigham And Women's Hospital S-nitrosothiols utilises comme decontracturants des muscles lisses et leurs utilisations therapeutiques
US5427797A (en) * 1993-04-06 1995-06-27 Brigham And Women's Hospital Systemic effects of nitric oxide inhalation

Also Published As

Publication number Publication date
LU90886I2 (fr) 2002-03-25
ATE376850T1 (de) 2007-11-15
EP0560928B1 (fr) 1997-09-24
CA2097823C (fr) 1999-06-29
DE69133575T2 (de) 2008-04-17
DE122008000012I2 (de) 2012-04-12
JP3510755B2 (ja) 2004-03-29
DE10299002I1 (de) 2012-07-05
US5873359A (en) 1999-02-23
EP0560928A1 (fr) 1993-09-22
DE69133584T2 (de) 2008-08-21
NL300081I2 (nl) 2002-06-03
ES2288660T5 (es) 2015-05-29
GR3024865T3 (en) 1998-01-30
DE122008000012I1 (de) 2008-08-14
LU91404I2 (fr) 2008-02-21
EP1516639A1 (fr) 2005-03-23
DK0560928T3 (da) 1997-12-01
JP2701978B2 (ja) 1998-01-21
EP0786264A2 (fr) 1997-07-30
ATE158509T1 (de) 1997-10-15
DE69133584T4 (de) 2009-11-19
DK0786264T3 (da) 2008-03-10
SG47527A1 (en) 1998-04-17
ES2082732T1 (es) 1996-04-01
GR990300018T1 (en) 1999-06-30
WO1992010228A1 (fr) 1992-06-25
EP0786264B1 (fr) 2007-10-31
NL300081I1 (nl) 2002-04-02
NL300342I1 (nl) 2008-06-02
DE122007000103I1 (de) 2008-04-03
NL300327I2 (nl) 2008-04-01
CA2097823A1 (fr) 1992-06-06
US5485827A (en) 1996-01-23
LV12201A (lv) 1999-01-20
EP1875917A3 (fr) 2012-11-28
DE69127756D1 (de) 1997-10-30
HK1010101A1 (en) 1999-06-11
ES2288660T3 (es) 2008-01-16
DK1516639T4 (en) 2015-06-29
JPH10158175A (ja) 1998-06-16
HK1020686A1 (en) 2003-06-19
EP1516639B1 (fr) 2007-07-25
JPH06504778A (ja) 1994-06-02
ES2132043T3 (es) 2008-04-01
GR960300032T1 (en) 1996-06-30
EP1875917A2 (fr) 2008-01-09
DE786264T1 (de) 2000-11-02
AU9149891A (en) 1992-07-08
DE69127756T2 (de) 1998-02-05
NL300327I1 (nl) 2008-03-03
DE560928T1 (de) 1994-09-22
DE69133575D1 (de) 2007-09-06
LU91423I2 (fr) 2008-06-30
EE03119B1 (et) 1998-10-15
JP3718491B2 (ja) 2005-11-24
EP0786264A3 (fr) 1997-08-13
AU657726B2 (en) 1995-03-23
EP0560928A4 (en) 1993-12-01
JP2003111845A (ja) 2003-04-15
DK1516639T3 (da) 2007-11-26
DE69133584D1 (de) 2007-12-13
EP1516639B2 (fr) 2015-04-15
HK1076407A1 (en) 2006-01-20
ES2082732T3 (es) 1997-12-16
ES2132043T1 (es) 1999-08-16
ATE367842T2 (de) 2007-08-15

Similar Documents

Publication Publication Date Title
AU657726B2 (en) Devices for treating pulmonary vasoconstriction and asthma
CA2186892C (fr) Methode de traitement de la vasoconstriction pulmonaire et de l&#39;asthme
US5823180A (en) Methods for treating pulmonary vasoconstriction and asthma
HK1010101B (en) Use of no for the treatment or prevention of bronchoconstriction
HK1112198A (en) Use of no for the treatment or prevention of reversible pulmonary vasoconstriction
HK1020686B (en) Devices for treating pulmonary vasoconstriction and asthma
HK1076407B (en) Use of no for treating persistent pulmonary hypertension of the newborn