|
JPH0637520B2
(ja)
|
1985-07-03 |
1994-05-18 |
味の素株式会社 |
ポリペプチド
|
|
JPS63502716A
(ja)
|
1986-03-07 |
1988-10-13 |
マサチューセッツ・インステチュート・オブ・テクノロジー |
糖タンパク安定性の強化方法
|
|
US4973577A
(en)
|
1986-04-04 |
1990-11-27 |
The Salk Institute For Biological Studies |
FSH-releasing peptides
|
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5198346A
(en)
|
1989-01-06 |
1993-03-30 |
Protein Engineering Corp. |
Generation and selection of novel DNA-binding proteins and polypeptides
|
|
US5096815A
(en)
|
1989-01-06 |
1992-03-17 |
Protein Engineering Corporation |
Generation and selection of novel dna-binding proteins and polypeptides
|
|
WO1992004913A1
(en)
|
1990-09-13 |
1992-04-02 |
Children's Hospital Medical Center Of Northern California |
Method for increasing red blood cell production by treatment with activin or activin-related peptides
|
|
US5118667A
(en)
|
1991-05-03 |
1992-06-02 |
Celtrix Pharmaceuticals, Inc. |
Bone growth factors and inhibitors of bone resorption for promoting bone formation
|
|
EP0542971A1
(en)
|
1991-05-10 |
1993-05-26 |
The Salk Institute For Biological Studies |
CLONING AND RECOMBINANT PRODUCTION OF RECEPTOR(S) OF THE ACTIVIN/TGF-$g(b) SUPERFAMILY
|
|
US5885794A
(en)
|
1991-05-10 |
1999-03-23 |
The Salk Institute For Biological Studies |
Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
|
|
US6162896A
(en)
|
1991-05-10 |
2000-12-19 |
The Salk Institute For Biological Studies |
Recombinant vertebrate activin receptors
|
|
US20050186593A1
(en)
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
US6287816B1
(en)
|
1991-06-25 |
2001-09-11 |
Genetics Institute, Inc. |
BMP-9 compositions
|
|
CA2108770C
(en)
|
1991-06-25 |
2007-04-03 |
John M. Wozney |
Bmp-9 compositions
|
|
US6692925B1
(en)
|
1992-11-17 |
2004-02-17 |
Ludwig Institute For Cancer Research |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
|
|
JPH08505771A
(ja)
|
1993-01-12 |
1996-06-25 |
ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン |
増殖分化因子−３
|
|
US5637480A
(en)
|
1993-05-12 |
1997-06-10 |
Genetics Institute, Inc. |
DNA molecules encoding bone morphogenetic protein-10
|
|
JPH09501305A
(ja)
|
1993-05-12 |
1997-02-10 |
ジェネティックス・インスティテュート・インコーポレイテッド |
Ｂｍｐ−１０組成物
|
|
US5677196A
(en)
|
1993-05-18 |
1997-10-14 |
University Of Utah Research Foundation |
Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
|
|
US5831050A
(en)
|
1993-06-07 |
1998-11-03 |
Creative Biomolecules, Inc. |
Morphogen cell surface receptor
|
|
CA2174098C
(en)
|
1993-10-14 |
2011-01-25 |
Douglas A. Melton |
Method of inducing and maintaining neuronal cells
|
|
US5525490A
(en)
|
1994-03-29 |
1996-06-11 |
Onyx Pharmaceuticals, Inc. |
Reverse two-hybrid method
|
|
US5658876A
(en)
|
1994-04-28 |
1997-08-19 |
The General Hospital Corporation |
Activin antagonists as novel contraceptives
|
|
US5885574A
(en)
|
1994-07-26 |
1999-03-23 |
Amgen Inc. |
Antibodies which activate an erythropoietin receptor
|
|
US5760010A
(en)
|
1995-01-01 |
1998-06-02 |
Klein; Ira |
Method of treating liver disorders with a macrolide antibiotic
|
|
US5814565A
(en)
|
1995-02-23 |
1998-09-29 |
University Of Utah Research Foundation |
Integrated optic waveguide immunosensor
|
|
JPH11502717A
(ja)
|
1995-04-11 |
1999-03-09 |
ザ ジェネラル ホスピタル コーポレーション |
逆ツーハイブリッドシステム
|
|
EP0771873A3
(en)
|
1995-10-27 |
1998-03-04 |
Takeda Chemical Industries, Ltd. |
Neuronal cell-specific receptor protein
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US20050244867A1
(en)
|
1996-03-26 |
2005-11-03 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
KR20000052807A
(ko)
|
1996-10-25 |
2000-08-25 |
윌리암스 로저 에이 |
순환 교환된 에리트로포이에틴 수용체 아고니스트
|
|
US6605699B1
(en)
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
|
US6231880B1
(en)
|
1997-05-30 |
2001-05-15 |
Susan P. Perrine |
Compositions and administration of compositions for the treatment of blood disorders
|
|
CA2297489A1
(en)
|
1997-07-30 |
1999-02-11 |
Emory University |
Novel bone mineralization proteins, dna, vectors, expression systems
|
|
US6696260B1
(en)
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
|
US6891082B2
(en)
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
|
AU8666398A
(en)
|
1997-08-01 |
1999-02-22 |
Johns Hopkins University School Of Medicine, The |
Methods to identify growth differentiation factor (gdf) receptors
|
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
US6953662B2
(en)
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
CA2302525A1
(en)
|
1997-08-29 |
1999-03-04 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
US6696411B1
(en)
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
|
CN1317967A
(zh)
|
1998-09-17 |
2001-10-17 |
伊莱利利公司 |
蛋白质制剂
|
|
JP2002526073A
(ja)
|
1998-09-22 |
2002-08-20 |
龍 余 |
新規のヒト生長分化因子のコード配列、そのｄｎａ配列によりコードされるポリペプチド、およびこれらの製造方法。
|
|
US6472179B2
(en)
|
1998-09-25 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Receptor based antagonists and methods of making and using
|
|
US6548634B1
(en)
|
1998-09-30 |
2003-04-15 |
Chiron Corporation |
Synthetic peptides having FGF receptor affinity
|
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
|
US20040009535A1
(en)
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
|
ATE322681T1
(de)
|
1999-01-21 |
2006-04-15 |
Metamorphix Inc |
Inhibitoren für wachstumdifferenzierungsfaktor und ihre anwendungen
|
|
EP1174149A1
(en)
|
1999-04-19 |
2002-01-23 |
Kyowa Hakko Kogyo Co., Ltd. |
Proliferation inhibitor for androgen-independent tumor
|
|
US6468543B1
(en)
|
1999-05-03 |
2002-10-22 |
Zymogenetics, Inc. |
Methods for promoting growth of bone using ZVEGF4
|
|
PL356007A1
(en)
|
1999-11-12 |
2004-05-31 |
Maxygen Holdings Ltd |
Interferon gamma conjugates
|
|
KR100791797B1
(ko)
|
1999-12-15 |
2008-01-04 |
리서치 디벨럽먼트 파운데이션 |
인히빈 수용체로서의 베타글리칸 및 이의 용도
|
|
JP4487376B2
(ja)
|
2000-03-31 |
2010-06-23 |
味の素株式会社 |
腎疾患治療剤
|
|
US6627424B1
(en)
|
2000-05-26 |
2003-09-30 |
Mj Bioworks, Inc. |
Nucleic acid modifying enzymes
|
|
WO2002008277A2
(en)
|
2000-07-19 |
2002-01-31 |
Eli Lilly And Company |
Nucleic acids, vectors, host cells, polypeptides, and uses thereof
|
|
US6632180B1
(en)
|
2000-09-07 |
2003-10-14 |
John H. Laragh |
Method for evaluating and treating hypertension
|
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
AU1325102A
(en)
|
2000-10-16 |
2002-04-29 |
Phylos Inc |
Protein scaffolds for antibody mimics and other binding proteins
|
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
CA2429473C
(en)
|
2000-11-20 |
2011-02-15 |
The Board Of Trustees Of The University Of Illinois |
Membrane scaffold proteins
|
|
US20030082233A1
(en)
|
2000-12-01 |
2003-05-01 |
Lyons Karen M. |
Method and composition for modulating bone growth
|
|
AU2002236558A1
(en)
|
2000-12-01 |
2002-06-11 |
Regents Of The University Of California |
Method and composition for modulating bone growth
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
TW200526779A
(en)
|
2001-02-08 |
2005-08-16 |
Wyeth Corp |
Modified and stabilized GDF propeptides and uses thereof
|
|
US20040132675A1
(en)
|
2002-02-08 |
2004-07-08 |
Calvin Kuo |
Method for treating cancer and increasing hematocrit levels
|
|
US7294472B2
(en)
|
2001-03-14 |
2007-11-13 |
Caden Biosciences |
Method for identifying modulators of G protein coupled receptor signaling
|
|
WO2002074340A1
(fr)
|
2001-03-16 |
2002-09-26 |
Takeda Chemical Industries, Ltd. |
Procede de fabrication d'une preparation a liberation continue
|
|
ATE472609T1
(de)
|
2001-04-26 |
2010-07-15 |
Amgen Mountain View Inc |
Kombinatorische bibliotheken von monomerdomänen
|
|
DE60234202D1
(de)
|
2001-05-24 |
2009-12-10 |
Zymogenetics Inc |
Taci-immunoglobulin-fusionsproteine
|
|
IL159015A0
(en)
|
2001-05-25 |
2004-05-12 |
Genset Sa |
Polypeptides, their preparation and use
|
|
AUPR638101A0
(en)
|
2001-07-13 |
2001-08-09 |
Bioa Pty Limited |
Composition and method for treatment of disease
|
|
US6855344B2
(en)
|
2001-07-17 |
2005-02-15 |
Integrated Chinese Medicine Holdings, Ltd. |
Compositions and methods for prostate and kidney health and disorders, an herbal preparation
|
|
DE60234348D1
(de)
|
2001-07-17 |
2009-12-24 |
Teijin Ltd |
Selektionsverfahren für eine durch das austesten einer ppard aktivierenden wirkung charakterisierten substanz und arzneistoff
|
|
KR100453877B1
(ko)
|
2001-07-26 |
2004-10-20 |
메덱스젠 주식회사 |
연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
|
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
|
US6784154B2
(en)
|
2001-11-01 |
2004-08-31 |
University Of Utah Research Foundation |
Method of use of erythropoietin to treat ischemic acute renal failure
|
|
US20030144203A1
(en)
|
2001-12-19 |
2003-07-31 |
Voyager Pharmaceutical Corporation |
Methods for slowing senescence and treating and preventing diseases associated with senescence
|
|
US6998118B2
(en)
|
2001-12-21 |
2006-02-14 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery for neuronal protection
|
|
BR0307548A
(pt)
|
2002-02-11 |
2006-01-17 |
Genentech Inc |
Método de produção de uma variante de anticorpo, variante de anticorpo, composição, ácido nucléico isolado, vetor, célula hospedeira, processo para a produção de uma variante de anticorpo e método de determinação do coeficiente de associação de antìgeno de um anticorpo
|
|
US7192717B2
(en)
|
2002-02-21 |
2007-03-20 |
Wyeth |
GASP1: a follistatin domain containing protein
|
|
US20030219846A1
(en)
|
2002-02-28 |
2003-11-27 |
Pfizer Inc. |
Assay for activity of the ActRIIB kinase
|
|
US8053552B2
(en)
|
2002-04-18 |
2011-11-08 |
Mtm Laboratories, Ag |
Neopeptides and methods useful for detection and treatment of cancer
|
|
JP2006500925A
(ja)
|
2002-08-16 |
2006-01-12 |
ワイス |
Ｂｍｐ−２エストロゲン応答エレメントおよびその使用方法
|
|
BR0315316A
(pt)
|
2002-10-15 |
2005-08-16 |
Celgene Corp |
Métodos de tratar, prevenir ou controlar uma sìndrome mielodisplásica, e de reduzir ou evitar um efeito adverso associado com a administração de um segundo ingrediente ativo em um paciente sofrendo de uma sìndrome mielodisplásica, composição farmacêutica, forma de dosagem unitária, e, kit
|
|
AR047392A1
(es)
|
2002-10-22 |
2006-01-18 |
Wyeth Corp |
Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
|
|
US20040223966A1
(en)
|
2002-10-25 |
2004-11-11 |
Wolfman Neil M. |
ActRIIB fusion polypeptides and uses therefor
|
|
AU2002953327A0
(en)
|
2002-12-12 |
2003-01-09 |
Monash University |
Methods of diagnosing prognosing and treating activin associated diseases and conditions
|
|
AP2005003367A0
(en)
|
2003-02-07 |
2005-09-30 |
Prometic Biosciences Inc |
Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis.
|
|
US20040197828A1
(en)
|
2003-03-26 |
2004-10-07 |
Gaddy Dana P. |
Method for diagnosis and treatment of bone turnover
|
|
WO2010019832A2
(en)
|
2008-08-13 |
2010-02-18 |
Designer Molecules, Inc. |
Amide-extended crosslinking compounds and methods for use thereof
|
|
US20070184052A1
(en)
|
2003-05-09 |
2007-08-09 |
Lin Herbert Y |
Soluble tgf-b type III receptor fusion proteins
|
|
RU2322261C2
(ru)
|
2003-06-02 |
2008-04-20 |
Уайт |
Применение ингибиторов миостатика (gdf8) в сочетании с кортикостероидами для лечения нервно-мышечных заболеваний
|
|
AU2004262640B2
(en)
|
2003-06-16 |
2010-12-23 |
Ucb Manufacturing, Inc. |
Antibodies specific for sclerostin and methods for increasing bone mineralization
|
|
US7611465B2
(en)
|
2003-07-15 |
2009-11-03 |
Board Of Regents, The University Of Texas System |
Rapid and accurate detection of bone quality using ultrasound critical angle reflectometry
|
|
WO2005009460A2
(en)
|
2003-07-25 |
2005-02-03 |
Medexis, S.A. |
Pharmaceutical composition comprising activin a, alk-4 or derivatives thereof for the treatment of ophthalmic disorders or cancer
|
|
DE10335211A1
(de)
|
2003-08-01 |
2005-02-17 |
Robert Bosch Gmbh |
Kraftstoff-Einspritzvorrichtung für eine Brennkraftmaschine
|
|
US20070135336A1
(en)
|
2003-09-15 |
2007-06-14 |
De Kretser David |
Follistatin isoforms and uses thereof
|
|
US8895540B2
(en)
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
CA2553883C
(en)
|
2004-01-22 |
2013-04-02 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Anti-cancer antibodies with reduced complement fixation
|
|
US20050197292A1
(en)
|
2004-01-30 |
2005-09-08 |
Glennda Smithson |
Compositions and methods for treating T-cell mediated pathological conditions
|
|
US7625867B2
(en)
|
2004-03-26 |
2009-12-01 |
Acceleron Pharma Inc. |
BMP-3 propeptides and related methods
|
|
EP1730186A2
(en)
|
2004-03-31 |
2006-12-13 |
Xencor, Inc. |
Bmp-7 variants with improved properties
|
|
WO2005113590A2
(en)
|
2004-05-12 |
2005-12-01 |
Acceleron Pharma Inc. |
Bmp10 propeptides and related methods
|
|
EP1771557B1
(en)
|
2004-06-24 |
2014-12-31 |
Acceleron Pharma Inc. |
GDF3 Propeptides and Related Methods
|
|
EP2314617B1
(en)
|
2004-07-23 |
2015-06-24 |
Acceleron Pharma Inc. |
ActRII receptor polypeptides
|
|
JP2008509927A
(ja)
|
2004-08-12 |
2008-04-03 |
ワイス |
Ｇｄｆ−８阻害剤を使用する、糖尿病、肥満、および心臓血管疾患のための併用療法
|
|
WO2006039400A2
(en)
|
2004-09-29 |
2006-04-13 |
Mount Sinai School Of Medicine Of New York University |
Fsh and fsh receptor modulator compositions and methods for inhibiting osteoclastic bone resorption and bone loss in osteoporosis
|
|
US7879569B2
(en)
|
2004-11-09 |
2011-02-01 |
The Trustees Of The University Of Pennsylvania |
Methods for diagnosis of myelodysplastic syndromes (MDS)
|
|
EP1824796A4
(en)
|
2004-11-16 |
2010-02-17 |
Avidia Res Inst |
PROTEIN SKELETONS AND USES THEREOF
|
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
|
US7968091B2
(en)
|
2005-02-16 |
2011-06-28 |
The General Hospital Corporation |
Methods and compositions to regulate iron metabolism
|
|
EP1884235A1
(en)
|
2005-04-26 |
2008-02-06 |
Ajinomoto Co., Inc. |
Myeloerythroid progenitor differentiation inducer
|
|
JP2007099764A
(ja)
|
2005-09-09 |
2007-04-19 |
Ajinomoto Co Inc |
血糖低下剤
|
|
WO2007038703A2
(en)
|
2005-09-28 |
2007-04-05 |
Zymogenetics, Inc |
Il-17a and il-17f antagonists and methods of using the same
|
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
|
EA201692543A1
(ru)
|
2005-11-23 |
2017-08-31 |
Акселерон Фарма Инк. |
Антагонисты активина-actriia и их применение для стимулирования роста кости
|
|
US20070149458A1
(en)
|
2005-12-06 |
2007-06-28 |
Amgen Inc. |
Uses of myostatin antagonists
|
|
AU2006326815A1
(en)
|
2005-12-20 |
2007-06-28 |
Merck Frosst Canada Ltd. |
Heteroaromatic compounds as inhibitors of stearoyl-coenzyme A delta-9 desaturase
|
|
MX2008008340A
(es)
|
2005-12-21 |
2008-09-03 |
Schering Corp |
Tratamiento de enfermedad de higado graso no alcoholica usando agentes reductores de colesterol y/o antagonista/agonista inverso de receptor de histamina 3.
|
|
WO2007076127A2
(en)
|
2005-12-22 |
2007-07-05 |
Biogen Idec Ma Inc |
Condensed imidazoles or pyrazoles and their use as transforming growth factor modulators
|
|
US7361512B2
(en)
|
2006-01-20 |
2008-04-22 |
Beckman Coulter, Inc. |
Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency
|
|
JP2009531280A
(ja)
|
2006-01-25 |
2009-09-03 |
ウェルスタット セラピューティクス コーポレイション |
代謝障害を処置するための化合物
|
|
CN101394738A
(zh)
|
2006-02-28 |
2009-03-25 |
维尔斯达医疗公司 |
用于治疗代谢紊乱的化合物
|
|
US8008074B2
(en)
|
2006-03-20 |
2011-08-30 |
The Uab Research Foundation |
Compositions and methods for improving bone mass through modulation of receptors of PTH and fragments thereof
|
|
WO2007120767A2
(en)
|
2006-04-14 |
2007-10-25 |
Amgen Inc. |
Agonist erythropoietin receptor antibodies
|
|
EA200802213A1
(ru)
|
2006-05-09 |
2009-10-30 |
Химекуэст Фармасьютикалз, Инк. |
Способы лечения заболеваний крови
|
|
ES2382993T3
(es)
|
2006-07-21 |
2012-06-15 |
Lyne Laboratories, Inc. |
Composición líquida de acetato de calcio
|
|
GB0615129D0
(en)
|
2006-07-29 |
2006-09-06 |
Univ Cardiff |
Anti-cancer activity of BMP-9 and BMP-10 and their use in cancer therapies
|
|
WO2008030367A2
(en)
|
2006-09-01 |
2008-03-13 |
The General Hospital Corporation |
Selective myostatin inhibitors
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
US7547781B2
(en)
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
|
WO2008060139A1
(en)
|
2006-11-17 |
2008-05-22 |
Erasmus University Medical Center Rotterdam |
Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein
|
|
US20100003190A1
(en)
|
2006-12-08 |
2010-01-07 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Method for protecting renal tubular epithelial cells from radiocontrast nephropathy (RCN)
|
|
EP2103628A4
(en)
|
2006-12-14 |
2012-02-22 |
Forerunner Pharma Res Co Ltd |
MONOCLONAL ANTIBODY ANTI-CLAUDIN 3, AND TREATMENT AND DIAGNOSIS OF CANCER USING SUCH ANTIBODY
|
|
EP2124999B1
(en)
|
2006-12-18 |
2012-10-03 |
Acceleron Pharma, Inc. |
Activin-actrii antagonists and uses for treating anemia
|
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
|
AU2013221910B2
(en)
|
2006-12-18 |
2016-11-17 |
Acceleron Pharma Inc. |
Activin-ActRII antagonists and uses for increasing red blood cell levels
|
|
US20100028332A1
(en)
|
2006-12-18 |
2010-02-04 |
Acceleron Pharma Inc. |
Antagonists of actriib and uses for increasing red blood cell levels
|
|
MX354099B
(es)
|
2007-02-01 |
2018-02-13 |
Acceleron Pharma Inc |
Antagonistas de activina-actriia y usos para tratar o prevenir cancer de mama.
|
|
TWI432449B
(zh)
|
2007-02-02 |
2014-04-01 |
Acceleron Pharma Inc |
衍生自ＡｃｔＲＩＩＢ的變體與其用途
|
|
KR20160129095A
(ko)
|
2007-02-09 |
2016-11-08 |
악셀레론 파마 인코포레이티드 |
액티빈-ＡｃｔＲⅡＡ 길항제 및 암 환자에서 골 생장을 촉진시키기 위한 이의 용도
|
|
TWI454479B
(zh)
|
2007-03-06 |
2014-10-01 |
Amgen Inc |
變異之活動素受體多肽及其用途
|
|
EP2150560A1
(en)
|
2007-06-01 |
2010-02-10 |
Wyeth |
Methods and compositions for modulating bmp-10 activity
|
|
WO2009009059A1
(en)
|
2007-07-09 |
2009-01-15 |
Biogen Idec Ma Inc. |
Spiro compounds as antagonists of tgf-beta
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
DK2170396T3
(en)
|
2007-08-03 |
2017-03-13 |
Summit Therapeutics Plc |
PHARMACEUTICAL COMBINATIONS TO TREAT THE MUSCLE DYROPHY OF DUCHENNES
|
|
GB0715938D0
(en)
|
2007-08-15 |
2007-09-26 |
Vastox Plc |
Method of treatment of duchenne muscular dystrophy
|
|
WO2009025651A1
(en)
|
2007-08-17 |
2009-02-26 |
University Of Maine System Board Of Trustees |
Biologically active peptide and method of using the same
|
|
CA2699936A1
(en)
|
2007-09-18 |
2009-03-26 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
|
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
WO2009070243A2
(en)
|
2007-11-21 |
2009-06-04 |
Amgen Inc. |
Wise binding agents and epitopes
|
|
CA2718403A1
(en)
|
2008-03-13 |
2009-09-17 |
The General Hospital Corporation |
Inhibitors of the bmp signaling pathway
|
|
WO2009137075A1
(en)
|
2008-05-06 |
2009-11-12 |
Acceleron Pharma Inc. |
Anti-activin antibodies and uses for promoting bone growth
|
|
AU2009244308A1
(en)
|
2008-05-06 |
2009-11-12 |
Joslin Diabetes Center, Inc. |
Methods and compositions for inducing brown adipogenesis
|
|
KR20220002710A
(ko)
|
2008-06-26 |
2022-01-06 |
악셀레론 파마 인코포레이티드 |
액티빈-ａｃｔｒｉｉａ 길항물질을 투약하는 방법 및 치료된 환자의 모니터링
|
|
EP2318028B1
(en)
|
2008-06-26 |
2020-02-19 |
Acceleron Pharma Inc. |
Antagonists of soluble activin-actriia and uses for increasing red blood cell levels
|
|
PT2340031T
(pt)
|
2008-08-14 |
2019-07-25 |
Acceleron Pharma Inc |
Armadilhas de gdf para uso no tratamento de anemia
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
US8138142B2
(en)
|
2009-01-13 |
2012-03-20 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin in a patient in need thereof
|
|
CA2750559A1
(en)
|
2009-02-05 |
2010-08-12 |
Digna Biotech, S.L. |
Pharmaceutical formulations of tgf-.beta.1 inhibitor peptides
|
|
EP3275900A1
(en)
|
2009-04-27 |
2018-01-31 |
Novartis AG |
Compositions and methods for increasing muscle growth
|
|
CN102482339B
(zh)
|
2009-06-08 |
2015-06-17 |
阿塞勒隆制药公司 |
用于增加产热脂肪细胞的方法
|
|
EP2440577A4
(en)
|
2009-06-12 |
2013-01-23 |
Acceleron Pharma Inc |
SHORTEN ACTRIIB FC FUSION PROTEINS
|
|
RU2642302C1
(ru)
|
2009-08-13 |
2018-01-24 |
Акселерон Фарма Инк. |
Комбинированное применение ловушек gdf и активаторов рецепторов эритропоэтина для повышения содержания эритроцитов
|
|
BR112012005225B8
(pt)
|
2009-09-09 |
2023-01-10 |
Acceleron Pharma Inc |
Uso de uma proteína de fusão actriib-fc para o tratamento de um transtorno relacionado ao osso ou associado à perda de músculo por crescimento muscular insuficiente
|
|
WO2011056896A1
(en)
|
2009-11-03 |
2011-05-12 |
Acceleron Pharma Inc. |
Methods for treating fatty liver disease
|
|
WO2011063018A1
(en)
|
2009-11-17 |
2011-05-26 |
Acceleron Pharma Inc. |
Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
|
|
WO2012027065A2
(en)
|
2010-08-27 |
2012-03-01 |
Celgene Corporation |
Combination therapy for treatment of disease
|
|
DK2726099T3
(en)
|
2011-07-01 |
2018-11-05 |
Novartis Ag |
Method of treating metabolic disorders
|
|
DK3875104T3
(da)
|
2011-10-17 |
2025-02-03 |
Acceleron Pharma Inc |
Sammensætninger til behandling af ineffektiv erytropoiese
|
|
JP6298762B2
(ja)
|
2012-07-02 |
2018-03-20 |
協和発酵キリン株式会社 |
抗ｂｍｐ９抗体を有効成分とする、腎性貧血、がん性貧血などの貧血に対する治療剤
|
|
JP6401171B2
(ja)
|
2012-10-24 |
2018-10-03 |
セルジーン コーポレイション |
貧血の治療に使用するためのバイオマーカー
|
|
CN112957462A
(zh)
|
2012-10-24 |
2021-06-15 |
细胞基因公司 |
用于治疗贫血的方法
|
|
MX366336B
(es)
|
2012-11-02 |
2019-07-05 |
Celgene Corp |
Antagonistas de activina - actrii y usos para el tratar trastornos oseos y otros.
|
|
WO2015143403A1
(en)
|
2014-03-21 |
2015-09-24 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating ineffective erythropoiesis by inhibiting activin b and/or gdf11
|
|
AP2016009549A0
(en)
|
2014-04-18 |
2016-11-30 |
Acceleron Pharma Inc |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
BR112016029226A2
(pt)
|
2014-06-13 |
2017-10-17 |
Acceleron Pharma Inc |
métodos e composições para o tratamento de úlceras
|
|
MA41052A
(fr)
|
2014-10-09 |
2017-08-15 |
Celgene Corp |
Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii
|
|
MA41119A
(fr)
|
2014-12-03 |
2017-10-10 |
Acceleron Pharma Inc |
Méthodes de traitement de syndromes myélodysplasiques et d'anémie sidéroblastique
|
|
FI3227675T3
(fi)
|
2014-12-03 |
2023-05-25 |
Celgene Corp |
Aktiviini-actrii-antagonisteja ja niiden käyttöjä myelodysplastisen oireyhtymän hoitamiseksi
|
|
EP3294320A4
(en)
|
2015-05-13 |
2018-12-26 |
Celgene Corporation |
Treatment of beta-thalassemia using actrii ligand traps
|
|
EP4190805A3
(en)
|
2015-05-20 |
2023-08-16 |
Celgene Corporation |
In vitro cell culture methods for beta-thalassemia using activin type ii receptor ligand traps
|
|
CN116327952A
(zh)
|
2015-08-04 |
2023-06-27 |
阿塞勒隆制药公司 |
用于治疗骨髓增生性病症的方法
|
|
EP3370754A4
(en)
|
2015-11-04 |
2019-10-23 |
Acceleron Pharma Inc. |
METHOD FOR INCREASING ERYTHROCYTE CONCENTRATION AND TREATMENT OF INEFFICIENT ERYTHROPOIESE
|
|
JP7072507B2
(ja)
|
2015-11-23 |
2022-05-20 |
アクセルロン ファーマ インコーポレイテッド |
眼の障害を処置するための方法
|
|
RU2748278C2
(ru)
|
2016-07-15 |
2021-05-21 |
Акселерон Фарма Инк. |
Композиции и способы лечения легочной гипертензии
|
|
MX2019001043A
(es)
|
2016-07-27 |
2019-09-26 |
Acceleron Pharma Inc |
Metodos y composiciones para el tratamiento de la mielofibrosis.
|
|
JP7280182B2
(ja)
|
2016-10-05 |
2023-05-23 |
アクセルロン ファーマ インコーポレイテッド |
バリアントＡｃｔＲＩＩＢタンパク質およびその使用
|
|
HUE068733T2
(hu)
|
2017-06-14 |
2025-01-28 |
Celgene Corp |
Eljárások mieloproliferatív neoplazma-asszociált mielofibrózis anémia kezelésére
|
|
CN112969471A
(zh)
|
2018-10-31 |
2021-06-15 |
细胞基因公司 |
使用激活素-actrii配体陷阱治疗具有环状铁粒幼细胞的受试者中由极低、低或中等风险的骨髓增生异常综合征引起的贫血
|