LT1988910T - Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdas - Google Patents
Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdasInfo
- Publication number
- LT1988910T LT1988910T LTEP07752096.3T LT07752096T LT1988910T LT 1988910 T LT1988910 T LT 1988910T LT 07752096 T LT07752096 T LT 07752096T LT 1988910 T LT1988910 T LT 1988910T
- Authority
- LT
- Lithuania
- Prior art keywords
- acryloyloxyethylphosphorylcholine
- preparation
- containing polymer
- polymer conjugates
- conjugates
- Prior art date
Links
- LWLHCZLCSDUDEL-UHFFFAOYSA-O C[N+](C)(C)CC(O)=P(=O)CCOC(=O)C=C Chemical compound C[N+](C)(C)CC(O)=P(=O)CCOC(=O)C=C LWLHCZLCSDUDEL-UHFFFAOYSA-O 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
- C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77691606P | 2006-02-28 | 2006-02-28 | |
| PCT/US2007/005372 WO2007100902A2 (en) | 2006-02-28 | 2007-02-28 | Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT1988910T true LT1988910T (lt) | 2018-01-10 |
Family
ID=38459678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP07752096.3T LT1988910T (lt) | 2006-02-28 | 2007-02-28 | Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdas |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20100166700A1 (lt) |
| EP (2) | EP1988910B1 (lt) |
| JP (2) | JP5528710B2 (lt) |
| DK (1) | DK1988910T3 (lt) |
| ES (1) | ES2657628T3 (lt) |
| LT (1) | LT1988910T (lt) |
| PT (1) | PT1988910T (lt) |
| SI (1) | SI1988910T1 (lt) |
| WO (2) | WO2007100905A2 (lt) |
Families Citing this family (39)
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|---|---|---|---|---|
| JP2928685B2 (ja) | 1992-07-29 | 1999-08-03 | エナジーサポート株式会社 | ガス開閉器における開閉表示用指針軸の構造 |
| GB0301014D0 (en) | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
| PT1988910T (pt) | 2006-02-28 | 2018-02-07 | Kodiak Sciences Inc | Acriloiloxietilfosforilcolina contendo conjugados de polímeros e sua preparação |
| EP2334334A1 (en) | 2008-09-19 | 2011-06-22 | Nektar Therapeutics | Polymer conjugates of nesiritide peptides |
| DK2260873T3 (da) * | 2009-06-08 | 2019-09-16 | Biocompatibles Uk Ltd | Pcylering af proteiner |
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| KR20200067958A (ko) * | 2010-04-15 | 2020-06-12 | 코디악 사이언시스 인코포레이티드 | 고분자량 쌍성이온-함유 중합체 |
| CN101870735B (zh) * | 2010-06-02 | 2013-06-12 | 北京精益泰翔技术发展有限公司 | 一种新型高糖基化促红细胞生成素免疫融合蛋白 |
| WO2012061165A2 (en) * | 2010-10-25 | 2012-05-10 | Lu Xiandan Sharon | Methods and compositions for improving admet properties |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| NZ611076A (en) | 2010-12-01 | 2015-09-25 | Alderbio Holdings Llc | Anti-ngf compositions and use thereof |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| WO2013024051A1 (en) * | 2011-08-12 | 2013-02-21 | Ascendis Pharma A/S | Sustained release composition of prostacyclin |
| JP6195848B2 (ja) * | 2012-01-27 | 2017-09-13 | ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ | 糖ポリマーを用いた生体分子の安定化 |
| US9505737B2 (en) | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| JP6542128B2 (ja) | 2013-01-11 | 2019-07-10 | コルセア ファーマ インコーポレイテッド | トレプロスチニルのプロドラッグ |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| WO2015035342A2 (en) | 2013-09-08 | 2015-03-12 | Oligasis Llc | Factor viii zwitterionic polymer conjugates |
| US9840553B2 (en) * | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016061562A2 (en) | 2014-10-17 | 2016-04-21 | Kodiak Sciences Inc. | Butyrylcholinesterase zwitterionic polymer conjugates |
| EP3223802A4 (en) * | 2014-11-26 | 2018-07-04 | The Regents of The University of California | Stealth nanocapsules for protein delivery |
| US9643911B2 (en) | 2015-06-17 | 2017-05-09 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| US9394227B1 (en) | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| AU2016311385C1 (en) | 2015-08-24 | 2019-08-22 | Glaxosmithkline Intellectual Property (No.2) Limited | Biopharmaceutical compositions |
| JP7088454B2 (ja) * | 2015-12-30 | 2022-06-21 | コディアック サイエンシーズ インコーポレイテッド | 抗体および抗体複合体 |
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| CA3059938A1 (en) | 2017-04-14 | 2018-10-18 | Kodiak Sciences Inc. | Complement factor d antagonist antibodies and conjugates thereof |
| CN112203679A (zh) * | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| CA3130763A1 (en) | 2019-02-25 | 2020-09-03 | Ginkgo Bioworks, Inc. | Biosynthesis of cannabinoids and cannabinoid precursors |
| CN110627937B (zh) * | 2019-09-27 | 2021-03-30 | 西北大学 | 仿细胞膜聚合物的制备方法、及其修饰壳聚糖-金自组装载药纳米粒子的制备方法和应用 |
| WO2021072265A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN111978390B (zh) * | 2020-08-31 | 2022-10-14 | 上海景泽生物技术有限公司 | 聚乙二醇修饰的rhBNP及其用途 |
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| CN116970120A (zh) * | 2022-04-21 | 2023-10-31 | 大连理工大学 | 一种无重金属参与的引发聚合技术制备多肽或蛋白质-高分子偶联物的方法 |
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|---|---|---|---|---|
| US5162218A (en) | 1988-11-18 | 1992-11-10 | The Regents Of The University Of California | Conjugated polypeptides and methods for their preparation |
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| US7737237B2 (en) | 2002-11-07 | 2010-06-15 | Phodia Chimie | Controlled structure copolymer comprising an amphoteric or zwitterionic part |
| GB0301014D0 (en) | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
| BRPI0409322B8 (pt) * | 2003-04-11 | 2021-05-25 | Antriabio Inc | método para preparar um conjugado de insulina-polímero |
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| BRPI0414017B8 (pt) * | 2003-09-17 | 2021-05-25 | Nektar Therapeutics Al Corp | pró-fármaco polimérico de múltiplos braços, composição farmacêutica e método para a preparação de um pró-fármaco polimérico de múltiplos braços. |
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| US7906134B2 (en) | 2005-12-21 | 2011-03-15 | Abbott Laboratories | Room temperature-curable polymers |
| PT1988910T (pt) | 2006-02-28 | 2018-02-07 | Kodiak Sciences Inc | Acriloiloxietilfosforilcolina contendo conjugados de polímeros e sua preparação |
| EP2097119A4 (en) | 2006-11-21 | 2012-10-17 | Abbott Lab | USE OF A TERPOLYMER OF TETRAFLUOROETHYLENE, HEXAFLUORPROPYLENE AND VINYLIDENE FLUORIDE IN MEDICAMENTAL COATINGS |
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| US20100158850A1 (en) | 2008-12-23 | 2010-06-24 | The Regents Of The University Of Michigan | Dendrimer based modular platforms |
| DK2260873T3 (da) * | 2009-06-08 | 2019-09-16 | Biocompatibles Uk Ltd | Pcylering af proteiner |
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| KR20200067958A (ko) | 2010-04-15 | 2020-06-12 | 코디악 사이언시스 인코포레이티드 | 고분자량 쌍성이온-함유 중합체 |
| WO2013059137A1 (en) | 2011-10-17 | 2013-04-25 | Oligasis | High molecular weight zwitterion-containing polymers |
-
2007
- 2007-02-28 PT PT77520963T patent/PT1988910T/pt unknown
- 2007-02-28 DK DK07752096.3T patent/DK1988910T3/en active
- 2007-02-28 US US12/281,071 patent/US20100166700A1/en not_active Abandoned
- 2007-02-28 ES ES07752096.3T patent/ES2657628T3/es active Active
- 2007-02-28 WO PCT/US2007/005381 patent/WO2007100905A2/en not_active Ceased
- 2007-02-28 EP EP07752096.3A patent/EP1988910B1/en active Active
- 2007-02-28 EP EP17165316.5A patent/EP3222142A1/en not_active Withdrawn
- 2007-02-28 SI SI200731999T patent/SI1988910T1/en unknown
- 2007-02-28 WO PCT/US2007/005372 patent/WO2007100902A2/en not_active Ceased
- 2007-02-28 LT LTEP07752096.3T patent/LT1988910T/lt unknown
- 2007-02-28 JP JP2008557399A patent/JP5528710B2/ja active Active
-
2013
- 2013-08-05 US US13/959,563 patent/US8846021B2/en active Active
- 2013-11-13 JP JP2013235314A patent/JP5745009B2/ja active Active
-
2014
- 2014-08-11 US US14/456,875 patent/US20150050714A1/en not_active Abandoned
-
2019
- 2019-05-28 US US16/424,265 patent/US20200000930A1/en not_active Abandoned
-
2021
- 2021-12-16 US US17/553,605 patent/US20220096643A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014043456A (ja) | 2014-03-13 |
| WO2007100902A3 (en) | 2008-11-20 |
| JP2009532330A (ja) | 2009-09-10 |
| US8846021B2 (en) | 2014-09-30 |
| ES2657628T3 (es) | 2018-03-06 |
| EP1988910A4 (en) | 2013-03-06 |
| JP5745009B2 (ja) | 2015-07-08 |
| JP5528710B2 (ja) | 2014-06-25 |
| US20220096643A1 (en) | 2022-03-31 |
| EP1988910A2 (en) | 2008-11-12 |
| WO2007100905A2 (en) | 2007-09-07 |
| WO2007100905A3 (en) | 2008-10-16 |
| WO2007100902A2 (en) | 2007-09-07 |
| EP3222142A1 (en) | 2017-09-27 |
| US20150050714A1 (en) | 2015-02-19 |
| US20200000930A1 (en) | 2020-01-02 |
| US20130337534A1 (en) | 2013-12-19 |
| US20100166700A1 (en) | 2010-07-01 |
| SI1988910T1 (en) | 2018-02-28 |
| PT1988910T (pt) | 2018-02-07 |
| DK1988910T3 (en) | 2018-01-22 |
| EP1988910B1 (en) | 2017-12-06 |
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