KR20130063074A - Blood glucose and blood pressure decrease action composition - Google Patents
Blood glucose and blood pressure decrease action composition Download PDFInfo
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- KR20130063074A KR20130063074A KR1020110129384A KR20110129384A KR20130063074A KR 20130063074 A KR20130063074 A KR 20130063074A KR 1020110129384 A KR1020110129384 A KR 1020110129384A KR 20110129384 A KR20110129384 A KR 20110129384A KR 20130063074 A KR20130063074 A KR 20130063074A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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Abstract
본 발명은 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물에 관한 것으로, 현미배아 및 호분층, 야관문, 맥문동, 백출, 갈근, 율피, 오미자, 산수유, 뽕잎, 토사자, 둥굴레, 엉겅퀴, 지모, 구기자, 계피, 여주, 건강, 귀전우, 동충하초, 감초, 녹두, 들깨, 검은콩을 적합한 배합비로 혼합하여 사용할 경우 예상치못한 상승효과로 혈당의 정상화로 당뇨병은 물론 혈액을 깨끗이 하여 혈압을 정상화시켜 당뇨합병증을 치료하는 효과가있다.The present invention relates to a blood glucose lowering composition of diabetes mellitus and diabetic complications, brown rice embryo and whistle layer, night gate, mammundong, baekchul, brown root, yulpi, Schisandra chinensis, cornus, mulberry leaf, earth and sand, round stalk, thistle, jimo, wolfberry, cinnamon, Yeoju, Health, Cattle, Cordyceps Sinensis, Licorice, Mung Bean, Perilla, and Black Soybeans are used in combination with proper ratio to unexpectedly increase synergistic effect. Works.
Description
본 발명은 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물에 관한 것으로 더욱 상세하게는 현미배아 및 호분층, 야관문, 맥문동, 백출, 갈근, 율피, 오미자, 산수유, 뽕잎, 토사자, 둥굴레, 엉겅퀴, 지모, 구기자, 계피, 여주, 건강, 귀전우, 동충하초, 감초, 녹두, 들깨, 검은콩을 함유하는 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물에 관한 것이다.The present invention relates to a blood glucose lowering composition of diabetes mellitus and diabetic complications, and more specifically, brown rice embryos and whistle layer, night gate, gymundong, baekchul, brown root, yulpi, Schisandra chinensis, Cornus, mulberry leaf, earthworm, roundworm, thistle, jimo, goji berry It relates to a blood sugar lowering composition of diabetes mellitus and diabetic complications containing cinnamon, bitter melon, health, ear cow, cordyceps, licorice, green beans, perilla, black beans.
당뇨병은 현대인이 음식물을 과다하게 섭취하여 체내에서 완전연소 대사가 되지 않아 지방이 몸 구석구석에 쌓여 혈액은 잘흐르지 않고 막히기도 하고 내장에도 쌓여 췌장에 쌓이게 되면 인슐린을 분비하는 랑게르한스섬을 막아서 인슐린이 분비가 되지않아 소화흡수된 포도당이 몸세포에 전달이 잘되지않고 혈액속에 포도당이 많이 남아있어 혈당이 높아지는 것이다.Diabetes is not a complete metabolism of the body by modern people ingesting too much food, fat is accumulated in every corner of the body, blood is not flowing well, clogged in the intestines, when the pancreas accumulates in the pancreas, it blocks the island of Langerhans to secrete insulin to secrete insulin This is because the digested and absorbed glucose is not well delivered to the body cells and glucose remains in the blood, which increases blood sugar.
현재 당뇨병을 치료하는 약은 경구용 혈당강하제가 있으나 강제적으로 혈당만 내려주는 역할만 하므로서 몸은 쌓여가는 지방으로 당뇨합병증이라는 무서운 결과가 나타나는데 눈이 실명되고 치아가 빠지고 썩은 다리를 절단해야 하는 것이 현실이다.Currently, drugs to treat diabetes have oral hypoglycemic drugs, but they only act to force blood sugar down, so the body is accumulating fat, resulting in a terrible effect of diabetic complications, such as blinding eyes, missing teeth, and cutting off rotten legs. to be.
지방으로 모세혈관들이 모두 막혀버렸으니 의사가 처방한 항생제와 소염제를 먹어봐야 항생제와 소염제가 세균이 우글거리는 썩은 상처부위로 갈 수가 없으니 효과가 없는 것이 당연한 것이나 본 발명인 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물에 현미배아 및 호분층을 사용함으로서 막힌 모세혈관을 뚫어 당뇨합병증을 치료하는 예상치못한 상승작용을 하도록 하였다Since the capillaries are blocked with fat, antibiotics and anti-inflammatory drugs prescribed by a doctor can't go to the rotten wounds where bacteria can grow. The use of brown rice embryos and neutrophils in the working composition resulted in unexpected synergism in the treatment of diabetic complications by penetrating blocked capillaries.
본 발명은 식품으로 사용될 수 있는 한방재료를 이용하여 연구를 한 결과 당뇨병에 효과있는 적절한 배합비율을 알아내고 여기에 비타민B군과 식이섬유가 풍부한 현미배아 및 호분층을 다량첨가하여 현대인의 풍성한 식사를 완전연소시켜 지방을 분해배출하도록 함으로서 한방재료와 현미배아 및 호분층등 식품을 함께 사용하여 효과를 상승시키는 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 개발하여 제공하는데 그 목적이 있다.The present invention is a study using a herbal material that can be used as a food to find out the proper blending ratio effective for diabetes mellitus and vitamin B group and dietary fiber rich brown rice embryos and whistle layer added to the rich diet of modern people The purpose of the present invention is to develop and provide a blood glucose lowering composition for diabetic and diabetic complications by using a combination of herbal ingredients, brown rice embryos, and nutrient layers to increase the effect by completely burning and discharging fat.
상기의 목적을 달성하기 위해 본 발명은 현미배아 및 호분층, 야관문, 맥문동, 백출, 갈근, 율피, 오미자, 산수유, 뽕잎, 토사자, 둥굴레, 엉겅퀴, 지모, 구기자, 계피, 여주, 건강, 귀전우, 동충하초, 감초, 녹두, 들깨, 검은콩을 함유하는 것을 특징으로 하는 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 제공한다.In order to achieve the above object, the present invention is a brown rice embryo and whistle layer, night gate, mammundong, baekchul, brown root, yulpi, Schisandra chinensis, cornus, mulberry leaf, earthworm, roundworm, thistle, gimo, goji berry, cinnamon, bitter gourd, health, jeonwoowoo, Provided is a blood sugar lowering blood composition of diabetes mellitus and diabetic complications comprising Cordyceps sinensis, licorice, green beans, perilla, black beans.
이하 본 발명의 과제 해결수단에 대해 상세히 설명하면 다음과 같다.Hereinafter will be described in detail with respect to the problem solving means of the present invention.
현미배아 및 호분층은 쌀겨로서 쌀겨란 바로 현미에서 정백미로 도정하는 과정에서 생기는 과피, 종피, 호분층 등의 분쇄 혼합물이다. 따라서 쌀겨는 정백미의 부산물이지만 영양에 관해서는 대단히 우수한 재료인 셈이다. 쌀겨에는 비타민 A를 비롯해 B1,B6, 철분, 인, 미네랄 등 다양한 영양소들이 함유되어 있다. 특히 비타민 B 성분은 섭취한 당질을 연소 대사시켜 피를 깨끗이 하여 지방이 혈액과 혈관에 축적되는 것을 막아주는 역할을 한다. 따라서 혈압이 낮아진다고 한다. 쌀겨의 표준적인 화학 조성을 보면 수분 13.5％, 지방 18.3％, 당질 38.3％, 섬유 7.8％ , 회분 8.9％ 이다. 비타민 B1은 100 g 중 2.5mg이나 들어 있으며 지구력을 높여주는 옥타코사놀, 농약이나 중금속을 해독하는 휘친산이 함유되어 있고 비타민 E도 많다고 알려져 있다.The brown rice embryo and the whistle layer are rice bran, which is a crushed mixture of skin, seed, and whistle layer produced from the process of turning rice bran to white rice. Thus, rice bran is a byproduct of polished rice, but it is a very good ingredient in terms of nutrition. Rice bran contains vitamins A, B1, B6, iron, phosphorus and minerals. In particular, the vitamin B component burns and metabolizes the sugars ingested to cleanse the blood to prevent fat from accumulating in the blood and blood vessels. Therefore, blood pressure is lowered. The standard chemical composition of rice bran is 13.5% moisture, 18.3% fat, 38.3% sugar, 7.8% fiber, and 8.9% ash. Vitamin B1 contains 2.5mg of 100g, contains octacosanol that boosts endurance, phytoacids that detoxify pesticides and heavy metals, and is known to be high in vitamin E.
쌀겨를 먹으면 식물 섬유로 인해 장의 작용이 활발하게 되므로 배변이 촉진되어 아무리 지독한 변비도 해결할 수 있다. 또, 식물 섬유는 장내의 비피더스균(유산균)을 증가시켜 장 안에 기생하고 있는 세균의 균형을 유지시키는 기능까지 하고 있기 때문에 대장암도 예방된다. 비피더스균이 증가하면 장이 건강하게 되어 노화 방지에도 큰 몫을 담당한다고 알려져 있다.Eating rice bran is an active intestine due to plant fiber, which promotes bowel movements, and no matter how terrible constipation can be solved. In addition, plant fiber also prevents colon cancer because it increases the amount of bifidus bacteria (lactic acid bacteria) in the intestine to balance the bacteria parasitic in the intestine. Increasing Bifidobacteria leads to healthy gut, which is known to play a major role in preventing aging.
야관문은 비수리라고도 하며 야관문 30∼50그램에 오골계 살코기를 적당하게 넣고 은근한 불로 푹고아서 먹는다. 아니면 하루에 말린 야관문 40∼80그램에 물 한되를 붓고 물이 반으로 줄어들 때까지 달여서 수시로 차 대신 마신다. 야관문은 당뇨병의 혈당치를 낮추는 데에도 상당한 효력이 있다고 알려져 있다.Night view gate is also called non-suri, and it puts moderately golgogi lean meat at 30-50 grams of night view gate. Alternatively, pour a handful of water into 40 to 80 grams of dried night view doors a day and drink until tea is reduced in half and drink instead of tea. Night gates are known to have a significant effect on lowering blood sugar levels in diabetes.
맥문동은 베타 Sitosterol glucose를 다량 함유하고 있으며 체내의 체액을 만들고 가래를 삭이고 폐와 위장을 돕고 눈이 밝아지고 갈증이 없어지고 자양강장의 효과가 있다고 알려져 있다.Macmundong contains a large amount of beta-Sitosterol glucose and is known to produce body fluids, sputum, sputum, help the lungs and stomach, brighten eyes, quench thirst, and nourish tonic.
백출은 atractylone을 함유하고 있으며 소변이 잘나오며 위장을 돕고 갈증을 멈추게한다고 알려져 있다.It is known to contain atractylone, which is known to urinate well, help the stomach and stop thirst.
갈근은 칡뿌리이며 이소플라본화합물은 진경작용이 있다. 특히 이 작용은 다이드제인이라는 성분에서 세게 나타나는데 이 것은 편두통, 고혈압, 협심증 등 여러가지 대사기능 부전증에 써 본데 따르면 심장의 혈관을 확장하여 70∼80％의 환자들한테서 치료효과가 있었다고 한다. 또한 칡뿌리는 한방에서 땀을 나게하고 열을내리는 약이다. 열병이나 목안이 마르고 머리가 아픈데, 편도선염, 당뇨병, 어혈이나 상처를 낫게하는 데도 쓴다고 알려져 있다.Brown root is a root root and isoflavone compound has a hardening effect. In particular, this action appears hard in the ingredient called Dyzedein, which has been used in various metabolic insufficiencies such as migraine, hypertension, and angina pectoris to expand the blood vessels of the heart and to treat 70 to 80% of patients. It is also a medicine that makes sweat and heat in one shot. Fever or sore throat and sore head are known to help tonsillitis, diabetes, blood and wounds.
율피는 밤껍질로서 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.Yulpi is used with other herbal ingredients in the present invention as a chestnut to have antidiabetic efficacy.
오미자는 유기산으로 malic acid등을 함유하고 있으며 몸의 부족한 것을 도우고 오장을 돕고 여자의 음을 강하게 하고 남자의 정수를 만든다고 알려져 있다.Schisandra chinensis is an organic acid that contains malic acid and is known to help the body's lack, to help the intestines, to strengthen the sound of women and to make the essence of men.
산수유는 tannic acid등을 함유하고 있으며 신장이 약하거나 허리와 무릎아픈데 좋다고 알려져 있다.Cornus contains tannic acid and is said to be good for weak kidneys and lower back and knee pain.
뽕잎에서 당뇨에 효과적인 성분으로 알려진 것은 모란 에이(moran A)라는 성분과 알파 글루코시데이즈 제해제(α-glucosidase inhivitor)라고 알려진 노지리마이신(Nozirimycine)과 칼리스테진(calystegin) 등이 있지만 이들 성분말고도 다른 성분이 더 있으리라고 생각된다. 임상실험에서 20-30대 당뇨병 환자 3명에게 뽕잎을 먹인 결과, 10일 전후하여 요당(尿糖)이 최고 10.56에서 2.97g으로, 9.5에서 2.2g으로, 7.7에서 2.4g으로 각각 떨어졌다고 보고하면서 뽕잎을 먹은지 2-3일만에 입이 마르는 느낌이 없어졌다고 하였다. 또한 먹은지 10일 전후해서 오줌에서 나오는 당이 현저히 줄었다고 한다.The most effective ingredients for diabetes in mulberry leaves are Moran A and Nozirimycine, which is known as α-glucosidase inhivitor, and calistingin. I think there are other ingredients. In the clinical trials, mulberry leaves were fed to three diabetic patients in their twenties and thirties and reported that urine glucose dropped from 10.56 to 2.97 g, 9.5 to 2.2 g, and 7.7 to 2.4 g, respectively, around 10 days. He said that after 2-3 days of eating mulberry leaves, his mouth felt dry. Also, about 10 days after eating, the sugar from urine decreased significantly.
토사자는 주로 간과 신장을 보호하여 눈을 밝게 해주고, 양기를 도우며 신장 기능을 튼튼하게 해주며 또한 뼈를 튼튼하게 해주고 허리 힘을 세게 해주며, 신장의 기능이 약해 허리와 무릎이 시리고 아픈데에 효과가 있으며. 또한 오줌소태와 소변을 잘 보지 못하는 질병과 설사를 낫게 하며 당뇨에도 효과가 있다.Tosa mainly protects the liver and kidneys to brighten the eyes, nourish the body, strengthen the kidneys, strengthen the bones and strengthen the waist, and the kidneys are weak, which makes the waist and knees sore and sore. And In addition, urine digestion and urinary ill diseases and diarrhea are better, and diabetes is effective.
요즘엔 정력에 도움이 된다고해서 정력제의 재료중 하나로 쓰이기도한다.Nowadays it is also used as one of the energetic agents to help tackiness.
특히 환삼덩굴이라는 식물에 기생한 토사자의 경우 최고의 약성을 가진다고 알려져 있다.In particular, the earth and sand parasitic parasitic plant is known to have the best weakness.
둥굴레는 황정이라고도 하며 약리학적으로 둥굴레는 혈압과 심장, 혈당에 주로 작용한다.Dungole is also known as the imperial pharmacologically, Dungole is mainly acting on blood pressure, heart and blood sugar.
혈당이 높을 때 지속적으로 복용을 하면 혈당을 낮추는 작용을 한다.Continuously taking high blood sugar lowers blood sugar.
둥굴레는 허약체질, 폐결핵, 마른기침 그리고 당뇨병, 갈증, 그리고 심장을 튼튼하게 하여 심장쇠약, 협심증 등 심장질환이 있는 사람에게 좋다.It is good for people with heart disease such as weak constitution, pulmonary tuberculosis, dry cough and diabetes, thirst, and heart to strengthen heart failure, angina.
또 위로 들어가 위, 십이지장궤양이 있는 사람도 꾸준히 먹으면 속이 편안해짐을 느낄 수 있다.In addition, people with stomach and duodenal ulcers can feel comfortable if they eat continuously.
식은땀과 원인 모르게 얼굴로 열이 오르면서 가슴이 답답하거나 수족에 열감이 있어 갑갑하게 느껴지는 사람, 노화방지에도 좋은 식품으로 볼 수 있다고 알려져 있다.It is known to be a good food for people who feel cold because of cold sweat and fever that goes up to their face without knowing the cause.
엉겅퀴에서 추출해 낸 silymarin은 flavonolignan인 silibinin, silicristin, silidianin의 이성체의혼합물로서 마리아엉겅퀴의 성숙한 열매의 주 구성물질이다.Silymarin, extracted from thistle, is a mixture of isoflavins of the flavonolignans silibinin, silicristin, and silidianin, and is a major component of the mature fruit of Maria thistle.
동물간의 미토콘드리아 및 마이크로좀에서의 과산화지질의 생성을 억제하여 주는 효과와 ccl4에 의한 독성에 대해 보호작용도 있다.It also has the effect of inhibiting the production of lipid peroxide in the liver and mitochondria and microsomes between animals and also protects against toxicity by ccl4.
간세포막의 변화를 안정시킴으로써 간세포에 대한 직접적 보호작용도 있다고 알려져 있으며 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.It is also known to have a direct protective effect on hepatocytes by stabilizing changes in hepatocytes, and has anti-diabetic efficacy in combination with other herbal ingredients in the present invention.
지모는 청량해열약으로서 해열, 사지부종, 대소변에 좋고 설사, 가래를 삭히고 당뇨병에도 좋다고 알려져 있다.Jimo is a soft antipyretic medicine that is good for fever, limb edema, faeces, diarrhea, sputum and diabetes.
구기자는 자양강장약으로 폐결핵, 허약, 눈이밝아지고 당뇨병에 이용한다고 알려져 있다,Gugija is a nutritious tonic that is known to be used for pulmonary tuberculosis, weakness, brightening eyes, and diabetes.
계피는 발한, 해열, 진통약으로서 오한, 발열, 두통, 관절염, 신경통등에 효능이 있으나 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.Cinnamon is effective for sweating, antipyretic, analgesic, chills, fever, headache, arthritis, neuralgia, etc., but is used with other herbal ingredients in the present invention to have antidiabetic effects.
여주의 열매와 씨에는 식물인슐린(p-insulin)과 카란틴(charantin)이란 성분이 다량 함유되어 있다. 식물인슐린은 체내에서 인슐린과 비슷한 작용을 하는 펩타이드의 일종으로 간에서 당분이 연소되도록 돕고 또한 포도당이 체내에서 재합성되지 않도록 하여 당뇨병에 좋다고 알려져 있다.Yeoju's fruits and seeds contain high amounts of plant-insulin and charantin. Phytoinsulin is a type of peptide that acts similar to insulin in the body and is known to be good for diabetes by helping sugars to be burned in the liver and preventing glucose from resynthesizing in the body.
건강은 생강을 건조한 것으로 건위 흥분약으로 소화불량, 위부냉통, 가래분비과다, 신경성설사등에 좋으며 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.Health is a dry dry ginger as a stimulant for stomach digestion, stomach cold pain, excessive secretion of sputum, nervous diarrhea, etc. In the present invention is used with other herbal ingredients to have antidiabetic effect.
귀전우는 화살나무라고도 하며 파혈(破血)작용이 있어서 타박상, 어혈동통, 생리 불순, 산후어혈복통 , 풍습(風濕)으로 인한 사지마비동통과 월경불순, 폐경, 산후어혈복통, 동맥경화, 혈전등에 좋다고 알려져 있다.Anterior cow, also called arrowwood, has a bleeding effect on bruises, erythematosus, physiological impurity, postpartum celiac pain, limb paralysis due to customs and menstrual disorders, menopause, postpartum erythematosus pain, arteriosclerosis, and blood clots. It is known to be good.
동충하초는 곤충의 표피에 형성되는 약용버섯으로 면역기능강화, 중추신경진경, 항피로 작용이 있다고 알려져 있다.Cordyceps sinensis is a medicinal mushroom that forms on the epidermis of insects and is known to have an immune function, central nervous system, and anti-dermis effect.
감초는 동의보감에서 5장6부의 한열과 사기를 다스리며 모든약 성분과 독을 중화한다고 알려져 있다Licorice is said to control the heat and morale of chapter 5 and 6 in Dongbogam and neutralize all drug ingredients and poisons.
녹두는 몸속의 열기를 내려 줌으로 열로 인한 설사를 멎게 하고 갈증을 해소하며, 소변을 잘나오게 하여 신장기능이 떨어지거나 몸이 붓고 배가 불러 있을 때에 좋으며, 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.Mung beans lower the heat in the body to stop diarrhea due to heat and quench thirst, and it is good when the kidney function is poor or the body is swollen and swollen by urinating well. Has diabetes effects
들깨의 특징을 보면 자양강장제로서 효험이 있고 특히 여성의 건강과 미용에 좋다. 또한 풍부한 식물성 지방이 혈관의 노화를 방지해 준다. 또한 들깨는 고급불포화 지방산을 함유하고 있어 성인병을 예방하며 천식에도 유효하며 그리고 비타민 Eㆍ, F가 들어있어 피부를 아름답게 하는 미용효과도 있으며 또한 여름철 체력저하시나 산후 회복에도 도움을 주며, 변비증 치료와 중풍예방에도 도움을 준다고 알려져 있으며 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.The characteristics of perilla are effective as a nourishing tonic, especially for women's health and beauty. Abundant vegetable fats also help prevent blood vessels from aging. Perilla contains high-unsaturated fatty acids to prevent adult diseases and is effective for asthma, and contains vitamins E and F to make the skin beautiful. It also helps to relieve physical stress and recovery from postpartum in the summer. It is known to help prevent stroke and is used with other herbal ingredients in the present invention to have antidiabetic effects.
검은콩은 밭에서 나는 쇠고기라 불릴 정도로 그 영양가가 뛰어나다. 그 중에서도 검은콩은 약효 작용이 뛰어나 한방에서는 약재로 사용하고 있다. 검은콩은 여러 가지 독을 없애주고, 신장계통의 대사 촉진에 좋은 효과를 보인다고 한다. 신장계통이 약한 사람은 몸이 냉하고 신진대사가 원활하지 않아 몸에 여분의 수분이나 지방이 쌓이게 되는 것이다. 검은콩을 먹으면 신장의 작용이 활발해져 수분과 지방이 축적되지 않는 몸으로 체질이 개선된다. 또한 검은콩은 당뇨병이나 귀울림,백발등의 증상을 개선시키는 것으로 알려지고 있다. 검은콩은 양질의 단백질과 지질, 비타민B1, B2가 많이 들어 있는 영양이 풍부한 우수 식품으로 알려져 있으며 본 발명에서 다른 한약 재료와 함께 이용되어 항당뇨 효능을 가진다.Black beans are so nutritious that they are called beef from the field. Among them, black soybeans are excellent in medicine and are used as herbal medicines. Black soybeans remove various poisons and have a good effect on promoting metabolism of the kidney system. People with weak kidneys are cold body and metabolism is not smooth, so the body will accumulate extra moisture or fat. When you eat black beans, the kidneys are active, so the body does not accumulate moisture and fat, improving the constitution. In addition, black beans are known to improve symptoms such as diabetes, tinnitus, white hair. Black soybean is known as a nutritious rich food containing high quality protein and lipids, vitamins B1 and B2, and is used with other herbal ingredients in the present invention to have antidiabetic effects.
본 발명의 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물은 현미배아 및 호분층 20중량부를 기준으로 하여 야관문 3∼10중량부, 맥문동3∼10중량부 , 백출 3∼10중량부, 갈근 3∼10중량부 , 율피 3∼10중량부, 오미자 3∼10중량부, 산수유 3∼10중량부, 뽕잎 3∼10중량부, 토사자3∼10중량부 , 둥굴레 3∼10중량부, 엉겅퀴 3∼10중량부, 지모3∼10중량부 , 구기자 3∼10중량부, 계피 3∼10중량부, 여주3∼10중량부, 건강1∼5중량부, 귀전우1∼5중량부, 동충하초1∼5중량부, 감초1∼5중량부, 녹두1∼5중량부, 들깨1∼5중량부 , 검은콩 1∼5중량부를 포함하여 이루어진다.The blood sugar lowering action composition of the diabetic and diabetic complications of the present invention is 3-10 parts by weight, 3-10 parts by weight, 3-10 parts by weight, 3-10 parts by weight, 3-10 parts by weight, based on 20 parts by weight of brown rice embryos and neutrophils. 3-10 parts by weight, yulpi 3-10 parts by weight, 3-10 parts by weight of cornus oil, 3-10 parts by weight of mulberry leaves, 3-10 parts by weight of earthworms, 3-10 parts by weight, 3-10 parts by weight of thistle, 3-10 parts by weight of thistle , 3-10 parts by weight, 3-10 parts by weight of wolfberry, 3-10 parts by weight of cinnamon, 3-10 parts by weight of bitter gourd, 1-5 parts by weight, 1-5 parts by weight of barley cattle, 1-5 parts by weight of cordyceps 1 to 5 parts by weight of licorice, 1 to 5 parts by weight of mung beans, 1 to 5 parts by weight of perilla, and 1 to 5 parts by weight of black beans.
하기 실험예1에서 보는 바와 같이 본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 15일간 섭취후 공복혈당은 평균 14.6 이 저하되었고 식후 2시간 혈당은 평균 28.6 이 저하되었음을 알 수 있었다As shown in Experimental Example 1, after 15 days of ingesting the blood sugar lowering blood pressure-lowering composition of diabetes mellitus and diabetic complications, the fasting blood sugar was decreased by 14.6 on average and the blood sugar was decreased by 28.6 on average after 2 hours of eating.
불과 15일간 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 섭취하고도 평균 21.6 의 혈당이 저하 되었으니 계속 섭취할 경우 혈당은 정상적이 되고 당뇨병을 치료할 수 있다Only 15 days after taking the blood sugar lowering action composition of diabetes and diabetes complications, the average blood sugar of 21.6 is lowered, so if you continue to take the blood sugar is normal and can be treated diabetes
또한 15일간 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 섭취한뒤 최저혈압 평균이 12 저하되고 최대혈압 평균이 22.6 으로 저하되었다 이 사실은 혈관벽에 붙은 지방이 어느정도 분해되어 없어진 것을 뜻한다. 혈관벽이 유연하게 탄성이 생기면 혈압은 낮아지는 것이다.In addition, after taking the blood glucose lowering composition of diabetes and diabetic complications for 15 days, the mean blood pressure was lowered by 12 and the mean blood pressure was lowered by 22.6. This means that the fat attached to the blood vessel wall was partially decomposed. When the blood vessel wall becomes elastic, the blood pressure is lowered.
모세혈관이나 동맥과 정맥혈관이 지방으로 막히게 되어 당뇨합병증이 생기게 되는데 혈압의 저하효과를 보면 당뇨합병증을 치료할 수 있다고 추론된다.Capillaries, arteries and venous blood vessels are blocked with fat, resulting in diabetic complications. The lowering of blood pressure can be inferred from treating diabetic complications.
이하 본 발명의 구성 및 작용에 대해 하기 실시예에서 더욱 상세히 설명하지만 본 발명의 권리범위가 하기 실시예에만 한정되는 것이 아니고 당업자의 기술적 사상의 변형도 포함된다.Hereinafter, the configuration and operation of the present invention will be described in more detail in the following examples, but the scope of the present invention is not limited only to the following examples, and includes modifications of the technical spirit of those skilled in the art.
(제조예1)(Production Example 1)
현미배아 및 호분층 200g에 야관문 100g, 맥문동100g , 백출100g, 갈근100g , 율피100g, 오미자100g, 산수유 100g, 뽕잎 100g, 토사자100g , 둥굴레100g, 엉겅퀴 100g, 지모100g , 구기자 100g, 계피 100g, 여주100g, 건강50g, 귀전우50g, 동충하초50g, 감초50g, 녹두50g, 들깨50g , 검은콩 50g 각각의 분말을 통상적인 방법으로 환을 제조하였다.Brown ginseng and Hohoe layer 200g night tube 100g, Megmundong 100g, Baek 100g, brown root 100g, yulpi 100g, Schisandra chinensis 100g, Cornus 100g, Mulberry leaf 100g, Tosa 100g, 100g, Thistle 100g, Jimo 100g, Goji 100g, Cinnamon 100g , Health 50g, 50g of deciduous cow, 50g of Cordyceps sinensis, 50g of licorice, 50g of green beans, 50g of perilla, 50g of black soybean each powder was prepared in a conventional manner.
(실시예 1내지 실시예3) 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물 제조 (Example 1 to Example 3) Preparation of blood sugar lowering action composition of diabetes mellitus and diabetic complications
본 실시예1내지3은 상기 제조예1과 같은 방법으로 제조하였다Examples 1 to 3 were prepared in the same manner as in Preparation Example 1.
각 재료의 혼합시 효율적인 항당뇨 효과를 낼 수 있는 배합비를 결정하기 위해 배합비에 차이를 두고 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 제조하였으며 배합비에 따른 혈당과 혈압의 저하작용 효과를 하기 실험예에서 확인하였다In order to determine the compounding ratio that can have an effective anti-diabetic effect when mixing the ingredients, a blood sugar lowering action composition of diabetic and diabetic complications was prepared with a difference in the compounding ratio. Checked in
각각의 재료들의 배합비는 하기와 같다The compounding ratio of each material is as follows.
현미배아 및 호분층 200g에 야관문 100g, 맥문동100g , 백출100g, 갈근100g , 율피100g, 오미자100g, 산수유 100g, 뽕잎 100g, 토사자100g , 둥굴레100g, 엉겅퀴 100g, 지모100g , 구기자 100g, 계피 100g, 여주100g, 건강50g, 귀전우50g, 동충하초50g, 감초50g, 녹두50g, 들깨50g , 검은콩 50gBrown ginseng and Hohoe layer 200g night tube 100g, Megmundong 100g, Baek 100g, brown root 100g, yulpi 100g, Schisandra chinensis 100g, Cornus 100g, Mulberry leaf 100g, Tosa 100g, 100g, Thistle 100g, Jimo 100g, Goji 100g, Cinnamon 100g , Health 50g, Cattle 50g, Cordyceps Sinensis 50g, Licorice 50g, Mung Bean 50g, Perilla 50g, Black Bean 50g
현미배아 및 호분층 200g에 야관문 50g, 맥문동50g , 백출50g, 갈근50g , 율피50g, 오미자50g, 산수유50g, 뽕잎 50g, 토사자50g , 둥굴레50g, 엉겅퀴 50g, 지모50g , 구기자 50g, 계피 50g, 여주50g, 건강50g, 귀전우50g, 동충하초50g, 감초50g, 녹두50g, 들깨50g , 검은콩 50gBrown ginseng embryo and squid layer 200g, 50g night gate, 50g, 50g, Baekchul 50g, 50g, brown root, 50g, Omija 50g, Cornus 50g, Mulberry leaf 50g, Tosa 50g, 50g, Thistle 50g, 50g, Goji 50g, Cinnamon 50g , Health 50g, Cattle 50g, Cordyceps Sinensis 50g, Licorice 50g, Mung Bean 50g, Perilla 50g, Black Bean 50g
현미배아 및 호분층 200g에 야관문 30g, 맥문동30g , 백출30g, 갈근30g , 율피30g, 오미자30g, 산수유 30g, 뽕잎 30g, 토사자30g , 둥굴레30g, 엉겅퀴 30g, 지모30g , 구기자 30g, 계피 30g, 여주30g, 건강50g, 귀전우50g, 동충하초50g, 감초50g, 녹두50g, 들깨50g , 검은콩 50gBrown ginseng and Hohoe layer 200g night gwanmun 30g, Mcmundong 30g, Baekchul 30g, brown root 30g, Yulpi 30g, Schisandra chinensis 30g, Cornus 30g, Mulberry leaf 30g, Tosaja 30g, 30g, thistle 30g, Jimo 30g, Goji 30g, Cinnamon 30g, Yeo 30g , Health 50g, Cattle 50g, Cordyceps Sinensis 50g, Licorice 50g, Mung Bean 50g, Perilla 50g, Black Bean 50g
(실험예1)Experimental Example 1
본 실험에서 실험대상자는 당뇨병과 혈압이 높은 환자 3명(남자2명, 여자1명 평균년령 63세)에게 실시예 1내지3에서 제조한 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 15일간 매 식사시마다 8g씩 섭취하도록 하였다.In the present experiment, the subjects received blood glucose lowering blood composition of diabetes mellitus and diabetic complications prepared in Examples 1 to 3 for 15 days for 3 patients with high diabetes and high blood pressure (2 males, 1 female mean age 63 years). Take 8 grams each time you eat.
실험시작 이전부터 경구용 혈당강하제를 복용해온 대상군중 남자1명인 A는 계속약을 복용하면서 본 조성물을 섭취하도록하고, 평소 혈당강하제를 복용하지 않고 혈당이 높은 대상군중 남자1명인 B와 여자1명인 C는 본조성물만 섭취하도록 하며 일상적 생활을 하도록하였다.A male, one of the subjects who have been taking oral hypoglycemic drugs since the start of the experiment, should take the composition while taking continuous medicine, and one male and one female who had high blood sugar without taking the hypoglycemic agent. C was to eat only the composition and to live everyday.
본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물 섭취전과 섭취15일후 종료시 손가락 끝을 채혈하여 시험스트립(Blood Glucose Test Strips)와 혈당감지기(Blood Glucose Test Meter)로 공복혈당과 식후2시간 혈당을 측정하였다.Fasting and 2-hour postprandial blood glucose levels were measured using a blood glucose test strips and a blood glucose test meter at the tip of a finger before and after 15 days of ingestion of the blood glucose lowering composition of the diabetic and diabetic complications. .
혈압측정 실험또한 본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물의 섭취 전과 섭취 15일후 종료시 혈압계로 측정하였다.Blood pressure measurement experiment was also measured by a blood pressure monitor before and after 15 days of ingestion of the blood glucose-lowering composition of the present diabetes and diabetic complications.
(본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물의 섭취전)(Before intake of blood sugar lowering action composition of this diabetes and diabetic complication)
혈당량 단위: mg/dl Blood glucose unit: mg / dl
A (혈당강하제복용중) 공복혈당 160 식후2시간혈당 280A (during hypoglycemic use) Fasting blood glucose 160 2 hours after meals Blood sugar 280
B 공복혈당 172 식후2시간혈당 265B Fasting Blood Sugar 172 2 hours postprandial Blood Sugar 265
C 공복혈당 145 식후2시간혈당 210C Fasting Blood Sugar 145 2 hours postprandial Blood Sugar 210
A 최저혈압 120 최대혈압 190A minimum blood pressure 120 maximum blood pressure 190
B 최저혈압 126 최대혈압 185B Minimum Blood Pressure 126 Maximum Blood Pressure 185
C 최저혈압 115 최대혈압 176C lowest blood pressure 115 maximum blood pressure 176
(본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 15일간 섭취후)(After 15 days intake of blood sugar lowering action composition of this diabetes and diabetic complication)
혈당량 단위: mg/dl Blood glucose unit: mg / dl
A (혈당강하제복용중) 공복혈당 145(15저하) 식후2시간혈당 250(30저하)A (during hypoglycemic use) Fasting blood sugar 145 (15 lowered) 2 hours postprandial blood sugar 250 (30 lowered)
B 공복혈당 152 (20저하) 식후2시간혈당 227(38저하)B Fasting Blood Sugar 152 (20 drops) 2 hours postprandial Blood Sugar 227 (38 drops)
C 공복혈당 136 ( 9저하) 식후2시간혈당 192(18저하)C fasting blood sugar 136 (lower 9) 2 hours postprandial blood sugar 192 (lower 18)
A 최저혈압 110 최대혈압 175 (최저혈압10, 최대혈압15 저하)A minimum blood pressure 110 maximum blood pressure 175 (lowest blood pressure 10, lowering maximum blood pressure 15)
B 최저혈압 120 최대혈압 156 (최저혈압 6, 최대혈압 29 저하)B lowest blood pressure 120 maximum blood pressure 156 (lowest blood pressure 6, lowering maximum blood pressure 29)
C 최저혈압 95 최대혈압 152 (최저혈압20, 최대혈압24 저하)C lowest blood pressure 95 maximum blood pressure 152 (lowest blood pressure 20, lowering maximum blood pressure 24)
본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 15일간 섭취후 공복혈당은 평균 14.6 이 저하되었고 식후 2시간 혈당은 평균 28.6 이 저하되었음을 알 수 있었다After 15-day ingestion of the blood glucose-lowering composition of the diabetic and diabetic complications, the fasting blood glucose was decreased by 14.6 on average, and the blood sugar was decreased by 28.6 on average for 2 hours after eating.
본 당뇨병과 당뇨합병증의 혈당 혈압 저하작용 조성물을 15일간 섭취후 최저혈압은 평균 12 가 저하되었고 최대혈압은 평균22.6 이 저하되었음을 알 수 있었다After taking 15 days of hypoglycemic composition of diabetes mellitus and diabetic complications, the lowest blood pressure was 12 and the maximum blood pressure was 22.6.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109498737A (en) * | 2018-12-07 | 2019-03-22 | 扬子江药业集团有限公司 | A kind of pharmaceutical composition and its preparation method and application for treating metabolic disease |
| KR20200057973A (en) * | 2018-11-19 | 2020-05-27 | 국립낙동강생물자원관 | Composition for Anti-Diabetes Using an Extract of Lespedeza cuneata |
| KR102309486B1 (en) | 2020-12-17 | 2021-10-07 | 편정아 | Method of preparing functional tea comprised of Momordica charantia L. and leafs of Morus alba L. for prevention and improvement of diabetes mellitus and hypertension |
| CN114009770A (en) * | 2021-12-01 | 2022-02-08 | 海南中食肽科生物科技有限公司 | Blood pressure reducing composition and preparation method thereof |
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2011
- 2011-12-06 KR KR1020110129384A patent/KR20130063074A/en not_active Withdrawn
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200057973A (en) * | 2018-11-19 | 2020-05-27 | 국립낙동강생물자원관 | Composition for Anti-Diabetes Using an Extract of Lespedeza cuneata |
| CN109498737A (en) * | 2018-12-07 | 2019-03-22 | 扬子江药业集团有限公司 | A kind of pharmaceutical composition and its preparation method and application for treating metabolic disease |
| CN109498737B (en) * | 2018-12-07 | 2021-07-20 | 扬子江药业集团江苏龙凤堂中药有限公司 | Pharmaceutical composition for treating metabolic diseases and preparation method and application thereof |
| KR102309486B1 (en) | 2020-12-17 | 2021-10-07 | 편정아 | Method of preparing functional tea comprised of Momordica charantia L. and leafs of Morus alba L. for prevention and improvement of diabetes mellitus and hypertension |
| CN114009770A (en) * | 2021-12-01 | 2022-02-08 | 海南中食肽科生物科技有限公司 | Blood pressure reducing composition and preparation method thereof |
| CN114145374A (en) * | 2021-12-08 | 2022-03-08 | 山西振东五和医养堂股份有限公司 | Astragalus membranaceus and corn stigma composite tea and preparation method and application thereof |
| KR102475113B1 (en) * | 2022-09-30 | 2022-12-07 | 농업회사법인 김재식헬스푸드 주식회사 | Artificial rice and noodle composition with excellent blood sugar drop effect and method of manufacturing, and artificial rice and noodles prepared by the method |
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