KR20080009072A - 그렐린 결합형 핵산 - Google Patents

그렐린 결합형 핵산 Download PDF

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Publication number: KR20080009072A
Authority: KR; South Korea
Prior art keywords: nucleic acid; box; ghrelin; stretch box; stretch
Prior art date: 2005-04-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

KR1020077023000A

Other languages

English (en)

Korean (ko)

Inventor

플로리안 야로슈

디르크 율베르그

크리스티안 매쉬

스테펜 헬름링

스벤 클루스만

Original Assignee

녹손 파르마 아게

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-08

Filing date

2006-04-10

Publication date

2008-01-24

2006-04-10 Application filed by 녹손 파르마 아게 filed Critical 녹손 파르마 아게

2008-01-24 Publication of KR20080009072A publication Critical patent/KR20080009072A/ko

Status Abandoned legal-status Critical Current

Links

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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
- C—CHEMISTRY; METALLURGY
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
- C12N2310/3183—Diol linkers, e.g. glycols or propanediols
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed

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General Health & Medical Sciences (AREA)
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General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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KR1020077023000A 2005-04-08 2006-04-10 그렐린 결합형 핵산 Abandoned KR20080009072A (ko)

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EP05007795.7		2005-04-08
EP05007795		2005-04-08

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Country Status (24)

Country	Link
US (2)	US8101734B2 (fr)
EP (1)	EP1866412A2 (fr)
JP (2)	JP5308813B2 (fr)
KR (1)	KR20080009072A (fr)
CN (1)	CN101189337B (fr)
AP (1)	AP2007004189A0 (fr)
AR (1)	AR052741A1 (fr)
AU (1)	AU2006233647A1 (fr)
BR (1)	BRPI0608180A2 (fr)
CA (1)	CA2605377A1 (fr)
CR (1)	CR9423A (fr)
DO (1)	DOP2006000085A (fr)
EA (1)	EA200701901A1 (fr)
GB (1)	GB2439673A (fr)
GT (1)	GT200600137A (fr)
IL (1)	IL186085A0 (fr)
MA (1)	MA29384B1 (fr)
MX (1)	MX2007012419A (fr)
NL (2)	NL1031538C2 (fr)
PE (1)	PE20061358A1 (fr)
TN (1)	TNSN07375A1 (fr)
TW (1)	TW200718781A (fr)
UY (1)	UY29460A1 (fr)
WO (1)	WO2006108599A2 (fr)

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2006
- 2006-04-06 AR ARP060101371A patent/AR052741A1/es not_active Application Discontinuation
- 2006-04-06 UY UY29460A patent/UY29460A1/es not_active Application Discontinuation
- 2006-04-07 GT GT200600137A patent/GT200600137A/es unknown
- 2006-04-07 PE PE2006000380A patent/PE20061358A1/es not_active Application Discontinuation
- 2006-04-07 NL NL1031538A patent/NL1031538C2/nl not_active IP Right Cessation
- 2006-04-07 TW TW095112321A patent/TW200718781A/zh unknown
- 2006-04-07 DO DO2006000085A patent/DOP2006000085A/es unknown
- 2006-04-07 US US11/400,459 patent/US8101734B2/en not_active Expired - Fee Related
- 2006-04-10 MX MX2007012419A patent/MX2007012419A/es active IP Right Grant
- 2006-04-10 WO PCT/EP2006/003276 patent/WO2006108599A2/fr not_active Ceased
- 2006-04-10 CN CN2006800199540A patent/CN101189337B/zh not_active Expired - Fee Related
- 2006-04-10 GB GB0719489A patent/GB2439673A/en not_active Withdrawn
- 2006-04-10 CA CA002605377A patent/CA2605377A1/fr not_active Abandoned
- 2006-04-10 AP AP2007004189A patent/AP2007004189A0/xx unknown
- 2006-04-10 EP EP06724207A patent/EP1866412A2/fr not_active Withdrawn
- 2006-04-10 BR BRPI0608180-0A patent/BRPI0608180A2/pt not_active IP Right Cessation
- 2006-04-10 EA EA200701901A patent/EA200701901A1/ru unknown
- 2006-04-10 AU AU2006233647A patent/AU2006233647A1/en not_active Abandoned
- 2006-04-10 KR KR1020077023000A patent/KR20080009072A/ko not_active Abandoned
- 2006-04-10 JP JP2008504702A patent/JP5308813B2/ja not_active Expired - Fee Related
2007
- 2007-03-08 NL NL1033520A patent/NL1033520C2/nl not_active IP Right Cessation
- 2007-09-19 IL IL186085A patent/IL186085A0/en unknown
- 2007-10-05 TN TNP2007000375A patent/TNSN07375A1/fr unknown
- 2007-10-08 CR CR9423A patent/CR9423A/es not_active Application Discontinuation
- 2007-10-08 MA MA30282A patent/MA29384B1/fr unknown
2012
- 2012-01-24 US US13/356,816 patent/US20120115937A1/en not_active Abandoned
2013
- 2013-04-05 JP JP2013079688A patent/JP2013176372A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
EP1866412A2 (fr)	2007-12-19
CA2605377A1 (fr)	2006-10-19
CR9423A (es)	2007-12-17
US8101734B2 (en)	2012-01-24
AP2007004189A0 (en)	2007-10-31
MA29384B1 (fr)	2008-04-01
NL1031538A1 (nl)	2006-10-10
TW200718781A (en)	2007-05-16
EA200701901A1 (ru)	2008-04-28
AR052741A1 (es)	2007-03-28
CN101189337B (zh)	2013-11-06
TNSN07375A1 (fr)	2009-03-17
UY29460A1 (es)	2006-11-30
WO2006108599A2 (fr)	2006-10-19
AU2006233647A1 (en)	2006-10-19
NL1031538C2 (nl)	2007-03-20
AU2006233647A2 (en)	2008-04-17
IL186085A0 (en)	2008-01-20
US20120115937A1 (en)	2012-05-10
JP2008534024A (ja)	2008-08-28
NL1033520C2 (nl)	2010-01-21
JP2013176372A (ja)	2013-09-09
NL1033520A1 (nl)	2007-08-06
WO2006108599A3 (fr)	2007-02-15
GT200600137A (es)	2006-11-22
CN101189337A (zh)	2008-05-28
PE20061358A1 (es)	2007-01-13
DOP2006000085A (es)	2006-11-15
MX2007012419A (es)	2007-12-05
GB0719489D0 (en)	2007-11-21
GB2439673A (en)	2008-01-02
US20060258607A1 (en)	2006-11-16
JP5308813B2 (ja)	2013-10-09
BRPI0608180A2 (pt)	2009-11-17

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CN103958682A (zh)	2014-07-30	结合胰高血糖素的核酸
EP4493695A2 (fr)	2025-01-22	Combinaison d'oligonucléotides de ciblage de stat3 et d'inhibiteurs de pd-l1
ES2368041T3 (es)	2011-11-11	Ácidos nucleicos de unión a ghrelina.
CN113383079A (zh)	2021-09-10	Cxcl8结合性核酸
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