KR20020078467A - Drink for tonic liver and Manufacture process the same. - Google Patents

Abstract

The present invention relates to a beverage for restoring liver function consisting of 15 herbal extracts having a liver protection and detoxification effect, including a bark tree, chopped dried bark tree leaves, stems, berries 30-50 wt% 2- 8% by weight, Schisandra chinensis 2-8% by weight, Injin mugwort 2-8% by weight, browning 2-8% by weight, licorice 2-8% by weight, genus 2-8% by weight, arbor 2-8% by weight, 2-8% by weight of wormwood, 2-8% by weight of Cordyceps sinensis, 2-8% by weight of raw grass, Angelica 2-8% by weight, White worm 2-8% by weight, Gardenia 2-8% by weight, Astragalus 2-8% by weight and In vivo alcohol concentration by providing a method for preparing a beverage consisting of mixing 2-8% by weight safflower seed, extracted in a reduced pressure heating reactor of 200 ~ 250 ℃, filtered through a filter and sterilized the filtrate at 100 ℃ for 3 minutes And by reducing the concentration of acetaldehyde can be effectively removed hangover according to intake and has the effect of interpolation.

Description

Drink for recovery of liver function and its manufacturing method {Drink for tonic liver and Manufacture process the same.}

The present invention relates to a beverage for recovering liver function and a method for manufacturing the same, and more particularly, to a beverage for liver function recovery consisting of 15 herbal extracts having a liver protection and detoxification effect, including larvae.

In general, the liver is the largest organ in the body, the food absorbed by the stomach to make the necessary components to the body metabolism to send to each part of the body and is also involved in detoxification, blood coagulation and blood volume control.

Impairment of liver function is often called the organ of silence, so that it is almost impossible to cure certain diseases, so it is not easy to prevent and find the symptoms. There are many causes of liver disease, but among them, alcohol damage to liver is typical, as evidenced by long-term clinical trials. If you drink a lot of alcohol, malnutrition and nutritional imbalances are caused by alcohol, and liver function is reduced. Alcohol damage is more a problem than the type of alcohol. Even if this is not so much, if you continue drinking or drinking for months for a day, it will put a heavy burden on your liver and your liver will be impaired and seriously damaged. However, even though many people are aware of the risk of liver damage caused by alcohol, quitting alcohol requires considerable willpower and courage and cannot be easily carried out by social factors. The next best option is to eat nutritious protein foods and take medicines to restore liver function.

In general, symptoms after excessive alcohol consumption include helplessness, headache, drowsiness, nausea, thirst, tension, excitement, paleness, sweating and bad breath. The cause of the hangover is not known to date, but alcohol Residual acetaldehyde in the body, which is modified during metabolism of is known to be a major cause of hangover.

Most of the workers continue to take or drink various medicines and drinks to get rid of hangovers and to restore liver function after drinking. Accordingly, various liver function recovery agents are being developed. Nowadays, many drinks containing herbal medicines are marketed. have.

However, a drink containing some herbal medicines may not only cause systemic boredom, abdominal bloating, vomiting or abdominal pain, but also have problems such as widespread use of expensive herbal medicines so that it is not widely distributed.

The present invention has been proposed to solve the above problems of the prior art, the object of the present invention, unlike the conventional simple health drinks, the interpolation (補肝) with a special function of the bark tree and 15 herbal extracts It is to provide a method for producing a functional health drink is configured.

In order to achieve the above object, the present invention is finely chopped dry bark leaves, stems, berries 30-50% by weight of wolfberry 2-8% by weight, Schisandra chinensis 2-8% by weight, Injin mugwort 2-8% by weight, browning 2 -8% by weight, licorice 2-8% by weight, genus 2-8% by weight of the gourd, 2-8% by weight of arbor, 2-8% by weight of tangleweed, 2-8% by weight of Cordyceps sinensis, 2-8% by weight of raw paper , 2-8 wt% Angelica, 2-8 wt% Baekja, 2-8 wt% Gardenia, 2-8 wt% Astragalus and 2-8 wt% Safflower Seed, and extracted in a reduced pressure heating reactor at 200-250 ° C. It is then filtered through a filter and the filtrate is sterilized for 3 minutes at 100 ℃ to provide a method for preparing a beverage for liver function recovery.

The barn tree is a key tree-shaped, broad-leaved chicken egg, light yellow-green flowers in early summer. Raspberry trees are used for nausea and urinating diseases to stop urinating the fruit or seeds, often with taps, and to stop vomiting and poisoning with poisonous medicines. This lowers the efficacy.

In order to enhance the liver function recovery effect is added to the gallbladder extract, which is known to have a sweet taste, to relieve headaches, and especially contains a glycyrrhizin component to detoxify.

Licorice, which is used as a taste enhancer of medicines because of its sweet taste, is used for the purpose of alleviating and harmonizing the effects of other drugs, and includes sputum cutting action, alleviating action, anti-inflammatory action, and antihistamine action. The genus of gourd has the effect of promoting diuretic action.

According to Sun Moon Seokhwa, Songhwa powder contains Choline, and Gojija (枸杞 子) contains betaine (Betaine). These two substances have _three methyl groups (-CH ₃ ) in their chemical structure, and these two substances are known to be effective in eliminating fatty liver due to chemical reactions in our bodies.

Other herbal medicines are as follows. Schisandra chinensis is a magnolia and plant that is excellent for treating nourishment tonic, cardiovascular action, fatigue recovery and nervous breakdown. Injin mugwort promotes bile secretion and has many ingredients necessary for antipyretic, urination, and liver protection. The elm tree has the ability to loosen the alcohol, harmonize the five intestines, make the urine look better, and enhance the function of the liver. Darae eliminates vomiting and burping, harmonizes Gi and blood, relaxes muscles and regulates the movement of the intestine, which prevents dry mouth and has a sweating effect. Cordyceps sinensis protects the lungs, strengthens the kidneys and acts as a nutritious tonic. The base is anxin, nourishing tonic, bonsin, fatigue recovery, saponin to protect the gastric mucosa. Angelica has a great effect on the blood and relieves pain such as anemia and angina. Baekchul is excellent in boil dryness and digestive ability, gardenia has excellent detoxification effect, Astragalus is good for tonic bosin action and swelling and numbness of the face, it has a great effect. Safflower seed is a nourishing tonic and good for fatty liver and cirrhosis.

The preparation method of the beverage for liver function recovery of the present invention is as follows. Chopped dry bark leaves, stems and berries 30-50% by weight, wolfberry 2-8% by weight, Schisandra chinensis 2-8% by weight, jinjin mugwort 2-8% by weight, browning 2-8% by weight, licorice 2-8% by weight %, Genus 2-8% by weight, arbor 2-8% by weight, 2-8% by weight, Cordyceps sinensis 2-8% by weight, raw paper 2-8% by weight, Angelica 2-8% by weight, Baekchul 2 -8% by weight, Gardenia 2-8% by weight, Astragalus 2-8% by weight, and Safflower seed 2-8% by weight, extracted at 200-250 ° C in a reduced pressure heating reactor, filtered through a filter and can packed, and then filtered at 100 ° C. Sterilize for several minutes and refrigerate at 0-5 ℃.

Stabilizers, honey and flavoring may be added to the beverage composition of the present invention described above. In addition, the beverage compositions of the present invention may be formulated into beverages, instant teas, granules, tablets and other formulations using generally known methods.

If the present invention will be described in detail based on the Examples as follows, the present invention is not limited to the Examples.

<Example 1>

Shredded dry bark leaves, stems, berries 40 kg and wolfberry 5 kg, Schisandra chinensis 5 kg, Injin mugwort 5 kg, Brown flower 5 kg, Licorice 4 kg, Gourd 4 kg, Aralia 4 kg, Thigh 4 kg, Cordyceps sinensis 4 kg, Base grass 4 kg, Angelica 4 kg, 4kg of white leachate, 4kg of gardenia, 2kg of astragalus and 2kg of safflower seed are mixed, extracted at 200 ~ 250 ℃ in a reduced pressure heating reactor, filtered and packaged with a filter, sterilized at 100 ℃ for 3 minutes, and stored at 0-5 ℃ for refrigeration.

Comparative Example 1

Finely chopped and dried dried bark and fruit from 200 ~ 250 ℃ in a reduced pressure heating reactor, filtered and packaged with a filter, sterilized for 3 minutes at 100 ℃ and then stored refrigerated at 0 ~ 5 ℃.

Experimental Example 1

For 30 healthy young adults, 150 ml of the beverage of Example 1 was taken 30 minutes before drinking and 30 minutes after drinking, and then measured five times with a breathalyzer five times after 1 hour, 2 hours, 3 hours, and 4 hours. Each result is shown in Table 1. From the results of Table 1, the hangover removal efficiency is good, and when taken after drinking it can be seen that the efficacy is better.

division Time after taking 1 hours 2 hours 3 hours 4 hours 30 minutes before drinking 0.054 0.031 0.016 0.000 30 minutes after drinking 0.057 0.025 0.009 0.000

Experimental Example 2

After mixing 100 ml of alcohol alcohol 95% ethyl alcohol to 1000 ml of the beverage of Example 1, the alcohol content was measured by liquid chromatography (HPLC) over time and the results are shown in Table 2. From the results in Table 2 it can be seen that after 4 hours the alcohol 100% removed.

time 1 hours 2 hours 3 hours 4 hours Alcohol removal efficiency 60% 88% 93% 100%

Experimental Example 3

Liver function recovery experiments were performed for the beverages of Example 1 and Comparative Example 1 as follows. The number of subjects and the age distribution were 10 males in their 20s, 10 males in their 30s and 10 males in their 40s. After taking the beverage of Example 1, a bottle of alcoholic beverages containing 25% alcoholic beverage was taken, and then blood was collected to measure GOT (glutamic oxaloacetic transaminase) and GPT (glutamic pyruvic transaminase). Also, without taking a drink, take a bottle of alcoholic liquor, 25% alcohol, and collect blood to measure GOT and GPT. In addition, blood alcohol reduction effect and blood glucose were measured and the results are shown in Table 3.

division After taking time GOT (unused) GOT GPT (unused) GPT (take) Blood alcohol reduction effect (%) Glucometer (mg / dl) Example 1 2 96 59 128 38 78 136 3 86 50 114 31 91 123 4 74 43 102 24 100 115 Comparative Example 1 2 107 68 137 46 71 142 3 92 61 125 40 88 134 4 83 58 111 39 93 129

As a result of measuring the average of GOT and GPT levels once per day, 2 months, according to the change of the GOT and GPT levels before and after the drink of Example 1, there is a remarkable effect on the recovery of liver function only after 4 hours after taking .

Experimental Example 4

Five ICR rats with an average body weight of 25 g were used as one experimental group, and 4.0 g / kg of ethanol was administered to the tail. After 1 hour, the rats in the intoxicated state were fed with the beverages of Example 1 and Comparative Example 1 Different doses are administered. The time to recover to the original state and wake up, that is, the sleep time after oral administration to the rat was measured and shown in Table 4 below. From the results of Table 4, when the same amount of 400mg / kg administered, it can be seen that the reduction in sleep time was improved by administering the beverage of Example 1 containing the components of the interpolation and detoxification effect than the beverage of Comparative Example 1 have.

division Drink dose (mg / kg) Sleep time Example 1 100 3 hours 34 minutes 21 seconds 200 2 hours 9 minutes 28 seconds 300 1 hour 37 minutes 43 seconds 400 54 minutes 11 seconds 500 1 hour 25 minutes 18 seconds Comparative Example 1 400 1 hour 59 minutes 56 seconds

Experimental Example 5

Five ICR rats with an average body weight of 25 g were used as one experimental group, and 4.0 g / kg of ethanol was administered to the tail. After 1 hour, the rats in the intoxicated state were fed with the beverages of Example 1 and Comparative Example 1 Different doses are administered. The time the rats were on rotarod was measured and shown in Table 5. When the 400 mg / kg of the beverage of Example 1 was administered for the longest time, it can be seen that the beverage of Example 1 has a great effect on reducing blood alcohol and acetaldehyde. In addition, the improvement of the perceptual symptoms is thought to be effective in the treatment of dementia.

division Drink dose (mg / kg) Time on Rota Road Example 1 100 26 minutes 35 seconds 200 51 minutes 8 seconds 300 1 hour 42 seconds 400 1 hour 13 minutes 29 seconds 500 1 hour 13 minutes 29 seconds Comparative Example 1 400 59 minutes 38 seconds

As described above, the beverage for restoring liver function according to the present invention can promote the alcohol metabolism in vivo to reduce the concentration of alcohol and acetaldehyde, thereby effectively removing the hangover caused by ingestion, and also using the herbal medicine As it is produced, there is an interpolating effect.

Claims (2)

Chop, dry and dry dried bark leaves, stems, berries and wolfberry, Schisandra chinensis, jinjin mugwort, brown flower, licorice, gourd genus, elm, taraxacum, cordyceps, raw grass, Angelica, baekrye, gardenia, yellow, and safflower seeds Drink for liver function recovery, characterized in that the extract comprises an active ingredient. Chopped dry bark leaves, stems and berries 30-50% by weight, wolfberry 2-8% by weight, Schisandra chinensis 2-8% by weight, jinjin mugwort 2-8% by weight, browning 2-8% by weight, licorice 2-8% by weight %, Genus 2-8% by weight, arbor 2-8% by weight, 2-8% by weight, Cordyceps sinensis 2-8% by weight, raw paper 2-8% by weight, Angelica 2-8% by weight, Baekchul 2 -8% by weight, Gardenia 2-8% by weight, Astragalus 2-8% by weight and Safflower seed 2-8% by weight, extracted in a reduced pressure heating reactor at 200-250 ℃, filtered through a filter and the filtrate was 100 ℃ Method for producing a beverage for liver function recovery, characterized in that it comprises sterilization for 3 minutes.