KR20020046278A - Personal care articles - Google Patents

Abstract

The present invention relates to a substantially dry disposable personal cleansing article comprising: a) a water-insoluble substrate comprising: 1) a soft first layer exhibiting a total scratch cover value of less than about 17%; And 2) a second peelable layer adjacent to the first layer, wherein the second layer exhibits a total scratch cover value of about 17% to about 70%; And b) a cleansing component in the vicinity of said first and second layers, wherein said component comprises from about 10% to about 1000% by weight of said water-insoluble substrate a foam-forming surfactant. Further, the present invention relates to a disposable personal cleansing article which is suitable for conditioning and is substantially dry. The articles have been found to be particularly useful for personal cleansing applications, i.e., for skin and hair.

Description

PERSONAL CARE ARTICLES

Personal care products, particularly cleansing and conditioning products, have traditionally been available in a variety of forms, such as bar soaps, creams, lotions, and gels. Typically, these products have been attempted to meet a number of criteria acceptable to consumers. These criteria include cleansing effects, skin tactility, warmth in the skin, hair and mucous membranes, and the volume of foam. An ideal personal cleanser should gently cleanse the skin or hair, cause little or no irritation, and should not accumulate intensely on the skin or hair or overly dry, even if used frequently.

It is also highly desirable to deliver the cleansing and conditioning efficacy as a disposable product. Disposable products are convenient because they eliminate the need to carry or store troublesome bottles, rods, jars, tubes, and other types of junk, including cleansing products and other products that can provide therapeutic or aesthetic benefits. Disposable products are also a more hygienic alternative to sponges, cleaning towels, or other cleansing tools for multiple reuse because they can manifest other undesirable features associated with bacterial growth, unpleasant odors, and repeated use Because.

The articles of the present invention surprisingly provide effective cleansing and / or therapeutic efficacy to the skin and hair in a simple, inexpensive and hygienic manner. The present invention provides the convenience of not having to transport, store or use separate tools (e.g., cleaning towels or sponges), cleansers and / or therapeutic efficacy products. The article is convenient for use as it is in the form of a single disposable personal care article or multiple disposable articles useful for cleansing as well as for the application of therapeutic or aesthetic agents. Moreover, the article is suitable for use in or in conjunction with another personal care tool designed for more frequent use. In this case, the article of the invention is usually placed or attached in a separate, non-disposable personal care tool, such as a bath towel or a cleaning towel. The disposable article of the present invention may also be removably attached to a handle or grip suitable for moving the article across the surface to be cleansed and / or treated (e.g., conditioned).

In a preferred embodiment, the articles of the present invention are suitable for personal care applications, but they may also be used in car care requiring the application of cleansing and / or agonists, such as waxes, conditioners, , Furniture care, animal care, and the like.

In a preferred embodiment of the present invention, the article is suitable for personal care applications and is useful for cleansing skin, hair and similar keratinous surfaces that require cleansing. The consumer wets the article with water and rubs them at the site to be cleansed. The article includes a water-insoluble substrate having a first layer of softness exhibiting a total scratch cover value of less than about 17% and a second layer of exfoliation exhibiting a total scratch cover value of from about 17% to about 70% A therapeutic active ingredient comprising a therapeutically active agent that is from about 10% to about 1000% by weight of the foam-forming surfactant or water-insoluble substrate, or both. Without being bound by theory, it is believed that a substrate having two or more textures increases foam formation, which in turn increases cleansing and exfoliation, and optimizes delivery and deposition of therapeutic or aesthetic agents that may be included in the article . It is also believed that the multi-texturing of this article can appeal to a wider variety of users representing a wide variety of skin types.

Summary of the Invention

The present invention relates to a disposable personal care article suitable for cleansing and substantially dry, comprising:

a) a water-insoluble substrate comprising:

1) a soft first layer exhibiting a total scratch cover value of less than about 17%; And

2) a second peelable layer adjacent to the first layer, wherein the second layer exhibits a total scratch cover value of from about 17% to about 70%; And

b) a cleansing component in the vicinity of the first and second layers, wherein the component comprises from about 10% to about 1000% by weight of the water-insoluble substrate of a foam-forming surfactant.

In another embodiment, the present invention relates to a disposable personal care article suitable for cleansing and substantially dry, comprising:

a) a water-insoluble substrate comprising:

1) a soft first layer showing a meter depth value with an average profile of less than about 8; and

2) a second peelable layer adjacent to said first layer, said second layer representing a meter depth value from an average profile of from about 8 to about 80; And

b) a cleansing component in the vicinity of the first and second layers, wherein the component comprises from about 10% to about 1000% by weight of the water-insoluble substrate of the foam-forming surfactant.

In another embodiment, the above-mentioned articles of the invention include a therapeutic efficacy component in place of or in addition to the cleansing component.

The present invention also relates to the cleansing and / or therapeutic treatment of skin and hair, comprising the steps of: a) wetting the article with water and b) contacting the wetted article with the skin or hair.

All percentages and ratios used herein are by weight unless otherwise stated, and all measurements are made at 25 占 폚 unless otherwise specified. The present invention may include, consist of, or consist essentially of any of the essential elements and components as well as the essential elements described herein.

Various implementations and / or individual features are disclosed in the description of the invention. As will be apparent to those skilled in the art, any combination of the above embodiments and features is possible and can lead to the preferred practice of the present invention.

All documents referred to herein, including patents, patent applications and published publications, are hereby incorporated herein by reference in their entirety.

Brief Description of Drawings

Figure 1 shows the arrangement of equipment for measuring the overall scratch cover value.

DETAILED DESCRIPTION OF THE INVENTION

As used herein, the term " disposable " refers to an article that is discarded or discarded from a general point of view after a limited number of uses, preferably less than 25 times, more preferably less than about 10 times, and most preferably less than about 2 times Used to mean.

As used herein, " substantially dry " means that the article of the present invention has a dry weight of less than about 0.95 gms, preferably less than about 0.75 gms, more preferably less than about 0.5 gms, even more preferably less than about 0.25 gms More preferably less than about 0.15 gms, and most preferably less than about 0.1 gms. Measurement of moisture retention is discussed later.

The personal care articles of the present invention include the following essential ingredients.

Water-insoluble substrate

The article of the present invention includes a water-insoluble substrate further comprising at least two layers. Preferably, the substrate layer has a different, smoother texture on the skin of the consumer than the second layer, which is more detachable when used. Both layers, however, are preferably non-invigorating, energizing the skin. As used herein, " non-impregnated " means that the layer has a thickness of greater than about 15, preferably greater than about 30, more preferably greater than about 50, even more preferably greater than about 15, as measured by the Abrasiveness Value measurement described below Quot; means an erosion value of greater than about 70, and most preferably greater than about 80. However, in all cases, each layer is defined as having both an inner and an outer surface, respectively. In both cases, the inner surface of the layer refers to the interior or innermost of the article of the present invention, and the outer surface of the layer is the exterior or outermost surface of the article. In general, the orientation of the article of the present invention is such that the orientation of the article is closer to the side of the article (i. E., The catching surface) suitable for catching, and the side of the article to be in contact with the site to be cleansed and / For example, closer to the skin / location contact surface. However, both sides of the article are suitable for contact with the skin.

Without being limited by theory, water-insoluble substrates enhance cleansing and / or therapeutic treatment. The substrate has a different texture on each layer or surface so that the gripping surface of the article is a texture different from the skin / region contact surface used at any time. The substrate can act as an effective foaming and peeling tool. As it is in physical contact with the skin or hair, the substrate significantly aids in cleansing and removing dirt, makeup, dead skin and other debris. However, in a preferred embodiment, the substrate is non-irritating or non-irritating to the skin.

The first and second layers

The water insoluble substrate of the present invention further comprises a first layer exhibiting a total scratch cover value of less than about 17% and a second layer of exfoliating exhibiting a total scratch cover value of between about 17% and about 70%. In addition, the water-insoluble substrate may be characterized as having a soft first layer that exhibits a meter depth value with an average profile of less than about 8 and a second peelable layer that exhibits a meter depth value with an average profile of from about 8 to about 80. In both cases, the first layer is preferably lofty and fluid permeable. As used herein, " lofty " means that the layer has a thickness of from about 0.04 inches to about 2 inches at 5 gms / in ² and a thickness of from about 0.00005 g / cm3 to about 0.1 g / cm3, preferably from about 0.001 g / 0.09 g / cm < 3 >. Both layers are useful for introducing or retaining cleansing ingredients in the article. Furthermore, the first and second layers are suitable for contact with the skin and hair. In the case of a two-layer article, each layer or surface of the article may serve for different purposes given their different physical properties. As defined in the measurements described below, the first layer is intended to be softer, while the second layer is intended to exhibit more delamination properties. Thus, while the first layer may be desirable for users with more sensitive skin, the second layer (or face) may be desirable for users with skin that is tougher and less susceptible to scratching. The amount of scratches per square area of the scratched area by the water-insoluble substrate layer of the present invention is represented by the total scratch cover value measured by the following measurement method. Similarly, the metric depth value in the average profile measures the average depth of the scratches on the scratched surface by the water-insoluble substrate layer. The values are measured using the measurement described below.

The method involves engraving the substrate along the test surface using a mechanical device and then examining the resulting scratch marks created on the test surface using different analytical techniques.

Metric depth measurement with total scratch cover value and average profile

The first layer of water insoluble substrate exhibits a total scratch cover value of less than about 17%, preferably less than about 15%, more preferably less than about 12%, and most preferably less than about 9%. The first layer also exhibits a meter depth value with an average profile of less than about 8, preferably less than about 7.75, more preferably less than about 7.5, and most preferably less than about 7.

The second layer of the water insoluble substrate of the present invention comprises from about 17% to about 70%, preferably from about 17% to about 27%, more preferably from about 17% to about 25%, most preferably from about 17% Represents a total scratch cover value of about 23%. Also, the second layer may have a pH of from about 8 to about 80, preferably from about 8 to about 50, more preferably from about 8 to about 40, even more preferably from about 8 to about 25, most preferably from about 8 to about An average profile of 15 indicates the meter depth value.

The difference in total scratch cover values exhibited by the first and second layers is preferably from about 8 to about 37, more preferably from about 8 to about 27, Still more preferably from about 8 to about 25, most preferably from about 8 to about 21. Similarly, the difference in meter depth value with the mean profile represented by the first and second layers is preferably from about 2 to about 20, more preferably from about 2 to about 15, even more preferably from about 2 to about 12 , And most preferably from about 2 to about 8.

In order to measure the meter depth value with the total scratch cover value and average profile, the following equipment is required.

1. Martindale Toothbrush Wear and Abrasion Tester: James H. Heal and Co. Ltd. Model 103, serial number 103-1386 / 2 upwards. Martin Dale 07-01-88. Texture testing and QC equipment. Foot area: 43 x 44 mm. 1 kg weight.

2. Transparent Perspex strips 11 x 8 cm (for example, ICI Acrylic) (for total scratch cover value measurement)

3. Capped polystyrene strip 11 x 8 cm. White High Impact A clean general purpose polystyrene layer on polystyrene, for example EMA Model Supply Name SS-20201L (for measuring meter depth values with an average profile)

4. Substrate to be tested.

5. White reflective card (Kodak).

6. Medium density filter (Kodak).

7. Proscan 1000 profile with built-in Proscan 1000 software Profilometer

Remove the plastic protective coating on the side to be scrubbed and rinse with ethanol (do not use tissue) to prepare a perspex / polystyrene strip for scratching. Place the strip on the non-invasive surface and air dry the strip. Tape the edges and attach the perspex / polystyrene strip to the base of the Martin Dale abrasion tester. Place the perspex / polystyrene strips on the base of the Martin Dale abrasion tester, centered beneath the path of the rubbing device, with the length of the strip in the direction of travel. The substrate is cut into 2.5 "x 2.5" pieces. Align the machine direction of the substrate with the direction of movement and attach the substrate piece to the rubbing foot of the Martin Dale abrasion tester using double-sided tape. With the supplied screws, fix the rubbing foot in the appliance. A 1 Kg weight is arranged on top of the rubbing foot assembly to ensure that the rubbing foot moves in only one direction (forward and backward). Cover the entire Martindale abrasion machine with a safety screen. The machine is set to operate at 50 cycles per minute. (Frequency = 0.833 Hz). When the machine stops, disassemble the foot assembly and remove the perspex / polystyrene strip from the base of the machine. Make a label indicating the substrate sample used for perspex / polystyrene streaks and store in a plastic bag.

In order to measure the total scratch cover value, the PERSPECS strip is analyzed using the following equipment.

1. Lightbox 'Landsco' Low Angle Light Box (UK Supplier: Printing & Packaging Machinery Agency)

2. Hitachi KP-M1 Black and White CCD Camera

3. Frame Store Synapse (Framestore Synapse, UK: Synoptics Ltd)

4. Image processing software (eg, Semper Software, available from Synoptics Ltd, UK)

Figure 1 shows how the equipment is set up for strip analysis. The parallel light is given as a parallel angle on the specimen surface at an angle of 60 degrees from the horizontal. The CCD camera is at an angle of 30 degrees from the sample surface side. At this angle, the unscratched specimen surface light is reflected from the camera to produce a 'dark' image, while a scratch creates a 'bright' image by reflecting some light towards the camera. Thus, the visible scratch surface is the surface oriented at a specific angle of the camera with respect to light. Thus, the deviation of the angle between the light, the specimen and the camera will cause a deviation in the actual appearance of the specimen. To minimize such deviations, a fixed, robust light box is used as a reliable and repeatable source of images (as opposed to guiding the fluid to visible light), and the specimen mount is made of a rigid material.

For the measurement report, the observation conditions were set as follows:

15 microns per image resolution point

ㆍ Observation range 7.68 x 7.68 mm

The image from the camera is digitized into a gray level of 256 by the frame store to represent an image matrix of 512 x 512 pixels. The total scratch cover value is calculated by measuring the total scratch area observed by the CCD camera and expressed as a percentage of the viewing area. This is calculated from the scratch image, using the following procedure. Primarily, corrections are observed that observe the blank specimen. It is used as a basic reference for unscratched materials. The blank reference shows a 20 - 25 lux luminous intensity as measured by a camera lens (about 85 mm from the specimen). A white reflective card, which is known to have a reflectivity of about 90%, is observed. This is used as a white reference value. The white reference value is 80-85 lux luminous intensity as measured by a camera lens (about 85 mm from the specimen). An additional medium density filter (0.2 OD) may be required in front of the camera to ensure that the white level is within the camera's brightness range.

Then, shadow adjustment / gray level mapping is performed. A basic shading adjustment algorithm is applied to all images to compensate for any large optical deviations through the specimen. This is due to a high-pass filter centered at 128 x 128 pixels. The gray level range is remapped to the logarithmic scale to obtain a more linear response to brightness. This is obtained by converting the gray level value of all pixels to P '(x, y) = ln (P (x, y)) where P' is the new image.

The image gray level is then evaluated. Then, each image is graded as a dark / white reference with a gray reference level ranging from 0 to 255 so that the average cancer reference value is mapped to zero and the average white reference value is mapped to 255.

To observe the scratches on the strip caused by the substrate, the scratch is enhanced by applying a high pass filter across the image, using a 16 x 16 center (effectively 240 x 240 micron area). Then, a threshold value for scratch observation is set for each image. This is defined as (image brightness average) * 90% + (image brightness SD). The threshold is carefully biased by the full brightness of the image, compensating for the brighter the image the more scratches are. Forms less than 4 points in the area are excluded. The circular shape is excluded (to remove some dust effects). The circularity of a particle is defined as (4 * [pi] * area) / (circumference ² ) and has a value of 0 to 1 (1 = complete circle). Particles having a value of more than 0.6 are excluded. Next, all residual forms are defined as visible scratches. Then, the total scratch area is calculated and expressed as a percentage of the observed area. This value is the total scratch cover value.

Analyze the polystyrene strips to measure the meter depth value with an average profile. The analysis involved attaching a scratchy polystyrene strip (scratched side up) onto the profilometer, tape across the center of the cell 1, 1. Check that the plate is flat. After the scan coefficient is set to the following coefficient, the scan is started.

Starting position 002.0 mm x 003.0 mm

Step 0.010 mm x 0.010 mm

Distance (stage) 1000 x 1000 ㎛

x-y resolution 10 탆

Roughness values Ra, Rz and Rmax are calculated and recorded with Proscan software

(Where Ra is the arithmetic average deviation of the evaluated profile. The arithmetic mean of the absolute longitudinal axis Z (x) values is within the sample length.

Ra = 1 / l ∫│Z (x) │dx (Integral from 0 to 1)

Rz: For each profile, the evaluation length is divided by 5 equal parts, and the sum of the largest profile peak height and the largest profile valley depth in each minute is calculated. Rz is the average of the five values.

Rmax: the sum of the largest profile peak height and the largest profile valley depth within the evaluation length.

NB: A scan of 1 cm x 1 cm uses 1000 profiles. The values of Ra, Rz and Rmax for each profile are averaged to obtain the result).

Rz is the average profile of the substrate tested and represents the meter depth value.

Erosion value measurement method

The erosion value represents the " non-burning " property of the first and second layers of the article. The layer of the present invention is slightly peelable, but is not rough on the skin. Therefore, erosion measurement involves engraving substrates along the test surface using a mechanical device, and then examining the resulting scratch marks created on the test surface using different analytical techniques.

The following equipment is required for the method.

1. Martin Dale Toothbrush Wear and Erosion Tester: James H. Heal and Co. Ltd. Model 103, serial number 103-1386 / 2 upwards. Martin Dale 07-01-88. Texture testing and QC equipment. Foot area: 43 x 44 mm. 1 kg weight.

2. Capped polystyrene strip 11 x 8 cm. A clean general purpose polystyrene layer on a white high impact polystyrene, for example EMA model supplier SS-20201L.

3. Substrate to be tested.

4. Glossmeter, for example Sheen Tri-Microgloss 20-60-85

Remove the plastic protective coating on the side to be scrubbed and rinse with ethanol (do not use tissue) to prepare a scratch polystyrene strip. Place the strip on the non-invasive surface and air dry the strip. Tape the edges and attach the polystyrene strip to the base of the Martin Dale Abrasion Tester. Place the polystyrene strip in the center of the strip under the path of the rubbing device in line with the direction of movement. Cut the substrate to 2.5 "x 2.5". Using a double-sided tape, match the machine direction of the substrate to the direction of movement, and attach the substrate sample to the rubbing foot of the Martin Dale abrasion tester. With the provided screws, fix the rubbing foot assembly in the machine. Arrange 1 Kg weight on top of the rubbing foot assembly to ensure that the rubbing foot moves in only one direction (forward and backward). Cover the entire Martindale abrasion machine with a safety screen. The machine is set to operate at 50 cycles per minute. (Frequency = 0.833 Hz). When the machine stops, disassemble the foot assembly and remove the polystyrene strip from the base of the machine. Label the substrate used for the polystyrene stipples and store in a plastic bag.

The strip is then analyzed. The strips are placed on a black construction paper background and five or more samples of the same substrate are analyzed to obtain reproducible averages. Place the Gloss Meter at right angles across the scratch surface of the polystyrene strip (so that the beam is at right angles to the scratch) and center. Select a 20 ° angle and measure the specimen to obtain the erosion value. As the erosion value decreases, the scratch or abrasiveness of the substrate increases.

Suitable materials for the first and second layers are selected from the group consisting of a cellulosic nonwoven, a non-loft nonwoven, a sponge (i.e. both natural and synthetic), a molding film, a batting and combinations thereof do. Preferably, the layer is selected from the group consisting of a cellulosic nonwoven, a non-loft nonwoven, a molded film, a batting, a foam, a sponge, a reticulated foam, a vacuum formed laminate, a scrim, a polymeric net and combinations thereof Materials. More preferably, the nonwoven fabric layer includes a material selected from the group consisting of a cellulosic nonwoven fabric, a non-loft nonwoven fabric, a molding film, a batting, and combinations thereof. As used herein, the term " nonwoven fabric " means that the layer does not include fibers that are woven as fabrics, but it is not necessary that the layers contain fibers at all, such as molded films, sponges, foams, scrims, When fibers are included in the layer, the fibers may be random (i.e., randomly arranged) and carded (i.e., plugged so that they are arranged primarily in one direction). Furthermore, the layer may be a composite material consisting of a combination of additional layers, i. E., Random and carded fiber plies.

In one embodiment, the polymeric net is arranged with the first layer, for example by lamination by chemical methods such as heat or adhesives, hydroentanglement, and the like. The arrangement enhances the integrity of the entire article as well as the first layer, thereby increasing the substantivity of the article. Polymeric nets useful herein (referred to herein as "scrim" materials) are described in detail in US Pat. No. 4,636,419, which is incorporated herein by reference. The scrim material may be formed directly at the time of extrusion or may be derived from a film extruded by stretching and splitting after fiberization or embossing. The scrim may be derived from polyolefins such as polyethylene or polypropylene, copolymers thereof, poly (butylene terephthalate), polyethylene terephthalate, nylon 6, nylon 66, and the like. Scrim materials are commercially available from a variety of sources. A preferred scrim material useful in the present invention is a polypropylene scrim available from Conwed Plastics (Minneapolis, MN). Another preferred scrim material is a polyethylene scrim, particularly low density polyethylene, also available from Conwed.

In another aspect of the present invention, applicants have also discovered that by introducing the stream material into the first layer and then heating, the sheet is provided with macroscopic three-dimensional features. The macroscopic three-dimensionality has been shown to greatly enhance the cleansing performance of the article even when the basis weight of the sheet is essentially uniform. In particular, when the scrim / fiber composition is heated and then cooled, macroscopic three-dimensional properties are obtained. The process results in scrim shrinkage (in the X-Y axis), and since they are attached to the fiber, the sheet has greater three-dimensional properties. As used herein, the term " X-Y axis " refers to a plane, plane, or plane perpendicular to the thickness of an article or component thereof. The X and Y axes usually correspond to the length and width of the sheet or sheet component, respectively. The term " Z-axis " as used herein refers to an axis perpendicular to the length and width of the cleansing sheet or components of the present invention. The Z axis usually corresponds to the thickness of the sheet.

The degree of three-dimensionality added is adjusted according to the degree of scrim / cleansing combination shrinkage (e.g., reduction by heating). The introduction of a scrim is particularly advantageous when the structure of the fibers is nonwoven, especially when the structure is hydrated. More details on suitable scrim material-containing nonwoven fabrics can be found in co-pending U.S. Application Nos. 09 / 082,396 and 09 / 082,349 (both filed on May 20, 1998, Fereshtehkho et al) Which is incorporated herein by reference.

The first and second layers may comprise a variety of natural and synthetic fibers or materials. As used herein, " natural " means a substance derived from plants, animals, insects or by-products of plants, animals and insects. Convenient substrate-starting materials are usually fibrous webs, including any conventional synthetic or natural fabric-length fibers or combinations thereof.

Non-limiting examples of natural materials useful in the present invention include, but are not limited to, silk fibers, keratin fibers, and cellulosic fibers. Non-limiting examples of keratin fibers include those selected from the group consisting of wool fibers, camel parent fibers, and the like. Non-limiting examples of cellulosic fibers include those selected from the group consisting of wood pulp fibers, cotton fibers, hemp fibers, jute fibers, flax fibers, and combinations thereof. Cellulosic fiber materials are preferred in the present invention.

Non-limiting examples of synthetic materials useful in the present invention include but are not limited to acetate fibers, acrylic fibers, cellulose ester fibers, modacrylic fibers, polyamide fibers, polyester fibers, polyolefin fibers, polyvinyl alcohol fibers, rayon fibers, polyethylene foams, ≪ / RTI > and combinations thereof. Examples of suitable synthetic materials include acrylic based, such as acrylon, creslan and acrylonitrile based fibers, olones; Cellulose ester fibers such as cellulose acetate, arnel and asel; Polyamides such as nylon (e.g., nylon 6, nylon 66, nylon 610 and the like); Polyesters such as portret, cordel and polyethylene terephthalate fibers, polybutylene terephthalate fibers, dark rons; Polyolefins such as polypropylene, polyethylene; Polyvinyl acetate fibers; Polyurethane foams, and combinations thereof. These and other suitable fibers and nonwoven fabrics made therefrom are described in Riedel, " Nonwoven Bonding Methods and Materials ", Nonwoven World (1987); The Encyclopedia Americana , vol. 11, pp. 147 - 153 and vol. 26, pp. 566-581 (1984); U.S. Patent No. 4,891,227 to Thaman et al. And U.S. Patent No. 4,891,228, each of which is incorporated herein by reference in its entirety.

Preferred polyolefin fibers are fibers selected from the group consisting of polyethylene, polypropylene, polybutylene, polypentene, and combinations and copolymers thereof. More preferred polyolefin fibers are fibers selected from the group consisting of polyethylene, polypropylene, and combinations and copolymers thereof. Preferred polyester fibers are fibers selected from the group consisting of polyethylene terephthalate, polybutylene terephthalate, polycyclohexylenedimethylene terephthalate, and combinations and copolymers thereof. More preferred polyester fibers are fibers selected from the group consisting of polyethylene terephthalate, polybutylene terephthalate, and combinations and copolymers thereof. The most preferred synthetic fibers of the first and second layers include solid staple polyester fibers comprising a polyethylene terephthalate homopolymer. Suitable synthetic materials include, but are not limited to, solid single component (i.e., chemically uniform) fibers, multiconstituent fibers (i.e., one or more material types constitute each fiber) and multicomponent fibers And synthetic fibers comprising two or more different filament types to produce larger fibers), and combinations thereof. Preferred fibers include bicomponent fibers, multi-component fibers, and combinations thereof. The bicomponent fibers may have a core-sheath arrangement or a side-by-side arrangement. In all cases, the first and second layers may include fibers comprising a combination of fibers comprising the material described above or a combination of the materials described above.

For core-sheet fibers, the core preferably comprises a material selected from the group consisting of polyolefins, polyesters, and combinations thereof, having a T _g greater than about 10 ° C above the sheet material. Conversely, the sheet of bicomponent fiber preferably comprises a polyolefin having a T _g of at least about 10 캜 lower than the core material, a polyester polyolefin having a T _g of at least about 10 캜 lower than the core material, and combinations thereof The material to be selected is included.

In any case of a side-by-side arrangement, a core-sheet arrangement or a solid single component arrangement, the fibers of the first and second layers may exhibit a helical or spiral or corrugated arrangement, to be.

Nylon fibers may be included in the preferred synthetic material for the first and / or second layer. More preferred synthetic materials include nylon fibers formed into a scrim layer to which additional nylon fibers are bonded such that additional fibers form an arc on the scrim layer.

Nonwoven fabrics produced from natural materials are most often composed of a net or sheet formed on a fine wire screen from a liquid suspension of fibers. The document is incorporated herein by reference in its entirety [CA Hampel et al., The Encyclopedia of Chemistry , 3rd edition, 1973, pp. 793-795 (1973); The Encyclopedia Americana , vol. 21, pp. 376-383 (1984); And GA Smook, Handbook of Pulp and Paper Technologies , Technical Association for Pulp and Paper Industry (1986).

Natural material nonwovens useful in the present invention can be obtained in a wide variety of commercial sources. Non-limiting examples of suitable commercial paper layers useful herein include: Airtex, a cellulose-based layer having a basis weight of about 71 gsy and available from James River (Green Bay, Wis.), ; And Walkisoft USA (Mount Holly, NC) with a basis weight of about 75 gsy and embossed air-infused cellulosic-based Walkisoft .

Additional suitable nonwoven materials include: U.S. Pat. No. 4,447,294 to Osborn on May 5, 1984; 4,603,176 (granted to Bjorkquist on June 29, 1986); 4,981,557 (granted to Bjorkquist on January 1, 1991); 5,085,736 (granted to Bjorkquist on Feb. 4, 1992); 5,138,002 (granted to Bjorkquist on August 8, 1992); 5,262,007 (granted to Phan et al. On Nov. 16, 1993); 5,264,082 (granted to Phan et al. On Nov. 23, 1993); 4,637,859 (granted to Trokhan on January 20, 1987); 4,529,480 (granted to Trokhan on July 16, 1985); 4,687,153 (granted to McNeil on Aug. 18, 1987); But are not limited to, those disclosed in U.S. Patent No. 5,223,096 (granted to Phan et al. On June 29, 1993) and U.S. 5,679,222 (issued to Rasch et al. Quot;

Methods for making nonwoven fabrics are well known in the art. In general, the nonwoven fabric may be fabricated by air adhesion, water adhesion, melt molding, co-forming, spun bonding, or by first cutting a fiber or filament from a long strand to a desired length, passing it through water or air currents, Air or water on the screen through which it passes. Subsequently, one or more of several types of bonding processes for fixing the individual fibers together in the product layer, regardless of their manufacturing method or composition, are performed to form a self-supporting net. In the present invention, the nonwoven layer may be prepared by a variety of processes including, but not limited to, pneumatic, hydration, thermal bonding, and combinations of the processes.

Nonwoven substrates derived from synthetic materials useful in the present invention can be obtained in a variety of commercial sources. Non-limiting examples of suitable first and second layer materials useful herein include those available from Veratec, Inc. Having a basis weight of about 61 grams per square meter (gsm), including about 50% rayon and 50% polyester, available from Walpole, Mass., HEF 40-047 ; Veratec, Inc. 0.0 > HEF 140-102 < / RTI > commercially available from Walpole, Mass., Containing about 50% rayon and 50% polyester and having a basis weight of about 67 gsm; Veratec, Inc. Lt; RTI ID = 0.0 > 100% < / RTI > of polypropylene and a basis weight of about 60 gsm, available from Walpole, Mass. 149-616; Veratec, Inc. Having a basis weight of about 90 gsm and containing about 69% rayon, about 25% polypropylene, and about 6% cotton, available from Novonet (Walpole, MA) 149-801; Veratec, Inc. Having a basis weight of about 120 gsm and containing about 69% rayon, about 25% polypropylene, and about 6% cotton, available from Novonet (Walpole, MA) 149-191; Veratec, Inc. (Walpole, Mass.), Having a basis weight of about 84 gsm and containing about 100% of polyester, a perforated hydrated textile material HEF Nubtex 149-801; A dry-formed perforated material Keybak, available from Chicopee (New Brunswick, NJ), containing about 75% rayon, about 25% acrylic fiber and a basis weight of about 51 gsm 951V; A perforated material, Keybak, available from Chicopee (New Brunswick, NJ), having about 75% rayon, about 25% polyester and a basis weight of about 47 gsm 1368; A perforated hydrated textile material Duralace®, available from Chicopee (New Brunswick, NJ), containing about 100% rayon and having a basis weight of about 48 gsm to about 138 gsm, 1236; A perforated hydrated textile material Duralace, available from Chicopee (New Brunswick, NJ), containing about 100% polyester and a basis weight of about 48 gsm to about 138 gsm, 5904; (Acrylate or EVA based) of about 70% rayon, about 30% polyester, and optionally about 5% w / w or less, available from Chicopee (New Brunswick, NJ) (8 x 6 per inch, 3 x 2 per cm) with a basis weight of < RTI ID = 0.0 > Chicopee 5763; A fiber composition comprising 50% rayon / 50% polyester / 0% rayon / 100% polyester or 100% rayon / 0% polyester, commercially available from Chicopee (New Brunswick, NJ) Of carded hydrated textile material Chicopee 9900 series (e.g., Chicopee 9931 (62 gsm, 50/50 rayon / polyester) and Chicopee 9950 (50 gsm, 50/50 rayon / polyester); Dupont Chemical Corp. Sontara 8868 < / RTI > containing about 50% cellulose and about 50% polyester and having a basis weight of about 72 gsm. Preferred nonwoven substrate materials have a basis weight of from 24 gsm to about 96 gsm, more preferably from about 36 gsm to about 84 gsm, and most preferably from about 42 gsm to about 78 gsm.

The first and second layers may also be polymeric mesh sponges, such as those described in published European patent application EP 702550A1, March 27, 1996, the entire disclosure of which is incorporated herein by reference. The polymeric mesh sponge includes multiple plies of extruded tubular netting mesh made from nylon, or from a polyamide of a strongly flexible polymer, such as an addition polymer of an olefinic monomer and a polycarboxylic acid.

The first and second layers may also include multiple materials, including molded films and composite materials, i.e., molded films. Preferably, the molded film includes plastic that tends to soften the skin. Suitable flexible plastic forming films include, but are not limited to, polyolefins, such as low density polyethylene (LDPE). If the nonwoven fabric layer comprises a plastic forming film, it is preferred that the nonwoven fabric layer be perforated, for example macroporated or microperforated so that the layer is permeable to the fluids. In one embodiment, the nonwoven layer comprises a plastic formed film that is only microporous. The surface deformation, i.e., the male side, of the micropore is preferably located on the inner surface of the second layer and preferably toward the interior side of the substrate, i.e. towards the cleansing component / therapeutic efficacy component. In certain embodiments involving perforations with petal-like edge edged surface deformations, the theory is that regardless of whether the surface deformation of the perforations is directed towards the surfactant-containing cleansing component / therapeutic efficacy component, To create a large number of valves on the inner surface of the layer that effect the folding of the petal-like edges of the surface deformations into the interior of the article to release the cleansing / therapeutic efficacy components contained therein, thereby extending the useful life of the article It is believed to be possible.

In another embodiment, the first layer and / or the second layer includes a plastic formed film micro-perforated and macro-perforated. In this embodiment, the layer is very suitable for contacting the site to be cleansed and / or treated, giving a fabric-like feel of the microporous film. Preferably, in this embodiment, the surface deformation of the micropore faces away from the surface deformation of the macropore on the layer (i. E. The first layer and / or the second layer). In this case, macro-perforation is believed to maximize the wetting / foaming of the overall article by the three-dimensional thickness formed from surface deformation under constant pressure and reduced pressure during use of the article, resulting in abundant foam formation.

In either case, the first layer and / or the second layer comprising the forming film preferably have a thickness of at least about 100 apertures / cm2, more preferably at least 500 apertures / cm2, even more preferably at least about 1000 apertures / / Cm < 2 >, and most preferably at least about 1500 pores / cm < 2 >. In a more preferred embodiment of the present invention, a range of about 5 cm 3 / cm 2 -s to about 70 cm 3 / cm 2 -s, more preferably about 10 cm 3 / cm 2 -s to about 50 cm 3 / cm 2 -s, And a first layer and / or a second layer having a water flux rate of about 15 cm3 / cm2-s to about 40 cm3 / cm2-s.

Suitable shaped films and molded film containing composite materials useful in the first and / or second layer of the present invention include those disclosed in U.S. Patent No. 4,342,314 (issued to Radel et al., Issued Aug. 3, 1982) U.S. Serial No. 08 / 326,571 and PCT Application No. US95 / 07435 filed on June 12, 1995 and U.S. Patent No. 4,629,643 issued to Curro et al. All of which are incorporated herein by reference in their entirety. Also, the first and / or second layer may be a molded film composite material comprising at least one molded film and at least one nonwoven fabric formed by vacuum-forming the layer. Suitable molded film composite materials include, but are not limited to, vacuum laminated composite molded film materials formed by combining a carded polypropylene nonwoven having a basis weight of 30 gsm with a forming film.

Additionally, the first and second layers are preferably bonded together to maintain the integrity of the article. The bonding may be accomplished by combining spot bonding (e.g., hot point bonding), continuous or discontinuous pattern bonding (e.g., thinning, etc.), or outer edge (or periphery) of the layer and / And a combination thereof. Bonding may also be arranged such that geometric shapes and patterns, such as diamonds, circles, squares, etc., are produced on the outer surface of the layer and on the resulting article.

It is also contemplated that the article of the present invention may be formed of a single composite layer having two surfaces of different textures, with the first layer and any additional layers being surface deformed. Thus, as a result, the water-insoluble substrate can be described as comprising a single composite layer having a double textured surface or surface.

In either case, it is preferred that the binding sites present between the first and second layers do not exceed about 50%, preferably no more than about 15%, more preferably no more than about 10% , And most preferably not more than about 8%.

Each layer discussed herein includes two surfaces, namely, an inner surface and an outer surface, each of which may have the same or different texture and erosion degrees. Preferably, the article of the present invention includes a substrate, and thus includes a soft layer on the skin. However, different substrate textures can be obtained by using different combinations of materials, using different manufacturing processes, or blending them. For example, a dual texture water insoluble substrate can be made to provide a more erosive surface for exfoliation and a personal care article having the advantage of having a softer hygroscopic surface for gentle cleansing and therapeutic treatment. In addition, individual layers of the substrate can be made in different colors, helping the user to differentiate the surface.

Furthermore, the article itself as well as the individual layers of the article can be manufactured in a wide variety of shapes and forms, including flat pads, thick pads, thin sheets, ball shaped tools, and irregularly shaped tools. The exact size of the layer will depend on the intended use and characteristics of the article and may range from a surface area size of from 1 square inch to hundreds of square inches. Particularly convenient layer and article shapes have a surface area of from about 5 in ² to about 200 in ² , preferably from about 6 in ² to about 120 in ² , more preferably from about 15 in ² to about 100 in ² , Circular, rectangular, hourglass, glove type or oval shape having a thickness of from about 1 mm to about 50 mm, preferably from about 1 mm to about 25 mm, more preferably from about 2 mm to about 20 mm But is not limited thereto.

Cleansing ingredient

The article of the present invention includes a cleansing component further comprising at least one surfactant. The cleansing component is placed near the water-insoluble substrate. In certain embodiments, the cleansing component is incorporated into a water insoluble substrate. In another embodiment, the cleansing component is deposited on one or both surfaces of the substrate. The article of the present invention includes a surfactant in an amount of from about 10% to about 1,000%, preferably from about 50% to about 600%, and more preferably from about 100% to about 250%, by weight of the water insoluble substrate do. The article of the present invention also includes a surfactant, preferably about 1 gram or more, based on the weight of the water-insoluble substrate. Thus, the cleansing component can be added to the substrate without the need for a drying process.

The surfactant of the cleansing component is preferably a foam-forming surfactant. As used herein, "foam-forming surfactant" refers to a surfactant that forms a foam or foam when blended with water to mechanically shake it. Surfactants are preferred because increased foam is important to consumers as an indicator of cleansing effectiveness. In certain embodiments, the combination of surfactant or surfactant is mild. As used herein, the term " mild " means that the article of the invention as well as the surfactant exhibits a skin mildness comparable to a synthetic bar based on mild alkylglyceryl ether sulfonate (AGS) surfactant, synbar it means. The method of measuring the mildness or the irritation of a surfactant-containing article is based on a skin barrier breakdown test. In this test, the milder the surfactant, the less skin barrier is destroyed. Skin barrier breakdown is measured by the relative amount of radiolabeled (tritiated) water (water) (3H-H ₂ O) that passes from the test solution through the skin epidermis into the physiological buffer contained in the dialysis chamber. These tests are described in TJ Franz, J. Invest. Dermatol. , 1975, 64, pp. 190-195; And U.S. Patent No. 4,673,525 issued to Small et al. On June 16, 1987. Other test methods for measuring surfactant mildness, well known to those skilled in the art, may also be used.

A wide variety of foam-forming surfactants are useful herein and are selected from the group consisting of anionic foam-forming surfactants, nonionic foam-forming surfactants, cationic foam-forming surfactants, amphoteric foam-forming surfactants, and mixtures thereof .

Anionic foaming surfactant

Non-limiting examples of anionic foam-forming surfactants useful in compositions of the present invention are described in McCutcheon's, Detergents and Emulsifiers , North American edition (1986), published by Allured Publishing Corporation; McCutcheon ' s, Functional Materials , North American Edition (1992); And U.S. Patent No. 3,929,678 (Laughlin et al., Issued December 19, 1975), each of which is incorporated herein by reference in its entirety.

A wide variety of anionic foaming surfactants are potentially useful herein. Non-limiting examples of anionic foaming surfactants include alkyl and alkyl ether sulfates, sulfated monoglycerides, sulfonated olefins, alkylaryl sulfonates, primary or secondary alkanesulfonates, alkyl sulfosuccinates, acyltaurates, Alkylsulfates, acylated peptides, alkyl ether carboxylates, acyl lactylates, acylsulfates, acylsulfates, acylsulfates, acylsulfates, acylstersulfonates, Anionic fluorosurfactants, and combinations thereof. Combinations of anionic surfactants can be used effectively in the present invention.

Anionic surfactants for use in the cleansing composition include alkyl and alkyl ether sulfates. The material each R1O-SO ₃ M and _{R1 (CH 2 H 4 O)} x -O-SO 3 M and has the formula: (wherein, R1 has from about 8 to about 24 carbon atoms, saturated or unsaturated, branched or non- Wherein x is from 1 to 10 and M is a water soluble cation such as ammonium, sodium, potassium, magnesium, triethanolamine, diethanolamine and monoethanolamine. Alkyl sulfates are typically monohydric alcohols Having from about 8 to about 24 carbon atoms) or other known sulfation techniques. The alkyl ether sulfates are typically formed into condensation products of ethylene oxide and monohydric alcohols (having from about 8 to about 24 carbon atoms) and then sulfated. The alcohol can be derived from fats, such as coconut oil or tallow, or it can be a compound. Specific examples of alkyl sulfates that can be used in the cleansing component include sodium, ammonium, potassium, magnesium or TEA salts of lauryl or myristyl sulfate. Examples of alkyl ether sulfates which may be used include ammonium, sodium, magnesium or TEA laureth-3 sulfate.

Another suitable anionic surfactant is a sulfate group Chemistry monoglyceride of formula _{R1CO-O-CH 2 -C (} OH) H-CH 2 -O-SO 3 M ( in the formula, R1 has from about 8 to about 24 Saturated or unsaturated, branched or unbranched alkyl group of carbon number, and M is a water soluble cation such as ammonium, sodium, potassium, magnesium, triethanolamine, diethanolamine and monoethanolamine. These are typically produced by reacting glycerin with a fatty acid (having from about 8 to about 24 carbon atoms) to form a monoglyceride followed by a subsequent sulfation of the monoglyceride with sulfur trioxide. An example of a sulfated monoglyceride is sodium coco monoglyceride sulfate.

Other suitable anionic surfactants include olefin sulfonates of the formula R1SO ₃ M (wherein, R1 is a mono-olefin from about 12 to about 24 carbon atoms, M is a water-soluble cation such as ammonium, sodium, potassium, magnesium, Triethanolamine, diethanolamine, and monoethanolamine). The compound can be prepared by sulfonating an alpha olefin with unsulfurized sulfur trioxide and then neutralizing the acid reaction mixture under the condition that all of the sultone formed in the reaction is hydrolyzed to the corresponding hydroxyalkal sulphonate. An example of a sulfonated olefin is sodium C14 / C16 alpha olefin sulphonate.

Other suitable anionic surfactants have the general formula R1-C ₆ H ₄ -SO there are linear alkyl benzene sulfonate of ₃ M (wherein, R1 has from about 8 to about 24, and saturated or unsaturated, branched or unbranched alkyl group having a carbon number , And M is a water soluble cation such as ammonium, sodium, potassium, magnesium, triethanolamine, diethanolamine and monoethanolamine. These are formed by sulfonating straight chain alkylbenzenes with sulfur trioxide. An example of such anionic surfactant is sodium dodecylbenzenesulfonate.

Other anionic surfactants suitable for this cleansing component include the primary or secondary alkane sulfonates of the formula R1SO ₃ M (wherein, R1 has from about 8 to about 24 saturated or unsaturated carbon atoms, branched or unbranched alkyl And M is a water soluble cation such as ammonium, sodium, potassium, magnesium, triethanolamine, diethanolamine and monoethanolamine. They are usually formed by sulfonating paraffins with sulfur dioxide in the presence of chlorine and ultraviolet radiation or by other known sulfonation methods. Sulfonation can occur at the secondary or primary position of the alkyl chain. Examples of alkanesulfonates useful herein include alkali metal or ammonium C13-C17 paraffin sulfonates.

Other suitable anionic surfactants include alkyl sulfosuccinates, including disodium N-octadecyl sulfosuccinamate; Diammonium laurylsulfosuccinate; Tetrasodium N- (1,2-dicarboxyethyl) -N-octadecylsulfosuccinate; Diamyl esters of sodium sulfosuccinic acid; Dihexyl esters of sodium sulfosuccinic acid; And dioctyl esters of sodium sulfosuccinic acid.

Also useful are taurates based on taurine, also known as 2-aminoethanesulfonic acid. Examples of taurates include those prepared by reacting dodecylamine with sodium isethionate as described in N-alkyltaurine, for example, U.S. Patent No. 2,658,072, the disclosure of which is incorporated herein by reference in its entirety. Other examples of taurine substrates include acyltaurine formed by reacting n-methyltaurine with a fatty acid (having from about 8 to about 24 carbon atoms).

Another group of anionic surfactants suitable for use in cleansing ingredients is acyl isethionate. Acyl isethionates typically the formula R1CO-O-CH ₂ CH ₂ has an SO ₃ M (wherein, R1 is a saturated or unsaturated, branched or unbranched alkyl group from about 10 to about 30 carbon atoms, M is a cation ). These are typically formed by reacting a fatty acid (having from about 8 to about 30 carbon atoms) with an alkali metal isethionate. Non-limiting examples of the acyl isethionate include cocoyl isethionate, sodium cocoyl isethionate, sodium lauroyl isethionate, and mixtures thereof.

Another suitable anionic surfactant is the formula _{R1-OCH 2 -C (OH)} H-CH 2 -SO there are alkyl glyceryl ether sulfonate of ₃ M (wherein, R1 is saturation of about 8 to about 24 carbon atoms, Or an unsaturated, branched or unbranched alkyl group, and M is a water soluble cation such as ammonium, sodium, potassium, magnesium, triethanolamine, diethanolamine and monoethanolamine. These are formed by reacting epichlorohydrin and sodium bisulfite with fatty alcohol (having from about 8 to about 24 carbon atoms) or by other known methods. One example is sodium coco glyceryl ether sulphonate.

It includes other suitable anionic surfactants have the general formula R1-CH (SO ₄₎ -COOH and sulfonated fatty acid formula _{R1-CH (SO 4) -CO} -O-CH 3 in the sulfonated methyl ester (In the formula, R1 Is a saturated or unsaturated, branched or unbranched alkyl group of from about 8 to about 24 carbon atoms. These are formed by sulfonating fatty acids or alkyl methyl esters (having from about 8 to about 24 carbon atoms) with sulfur trioxide or by other known sulfonation techniques. Examples include alpha-sulfonated coconut fatty acids and lauryl methyl esters.

Other anionic materials include monoalkyl, dialkyl and trialkyl phosphate salts formed by reacting phosphates such as phosphorus pentoxide with monovalent side chains or non-branched alcohols of from about 8 to about 24 carbon atoms. They may also be formed by other known phosphorylation methods. An example of such a group of surfactants is sodium mono- or dilauryl phosphate.

Other anionic materials include the formula _{R1CO-N (COOH) -CH 2} CH 2 include acyl glutamate corresponding to -CO ₂ M (wherein, R1 has from about 8 to about 24 carbon atoms, saturated or unsaturated, branched or non- A branched alkyl group or an alkenyl group, and M is a water-soluble cation). Non-limiting examples include sodium lauroyl glutamate and sodium cocoyl glutamate.

Other anionic materials include the formula _{R1CON (CH 3) -CH 2 CH} 2 -CO 2 include alkanoyl sarcoidosis when carbonate corresponding to M (wherein, R1 is saturation of about 10 to about 20 carbon atoms or an unsaturated, branched Or a non-branched alkyl group or alkenyl group, and M is a water-soluble cation). Non-limiting examples include sodium lauroyl sarcosinate, sodium cocoyl sarcosinate, and ammonium lauroyl sarcosinate.

Other anionic materials include the formula _{R1- (OCH 2 CH 2) x} -OCH 2 -CO 2 include alkyl ether carboxylates corresponding to the M (wherein, R1 has from about 8 to about 24 carbon atoms, saturated or unsaturated , Branched or unbranched alkyl or alkenyl group, x is 1 to 10, and M is a water soluble cation. Non-limiting examples include sodium laureth carboxylate.

Other anionic materials include the formula _{R1CO- [O-CH (CH 3} ) -CO] x -CO 2 include an acyl lactylate corresponding to the M (wherein, R1 has from about 8 to about 24 carbon atoms, saturated or unsaturated , Branched or unbranched alkyl or alkenyl group, x is 3, and M is a water soluble cation. Non-limiting examples include sodium cocoyl lactylate.

Other anionic materials include carboxylates, and non-limiting examples include sodium lauroyl carboxylate, sodium cocoyl carboxylate, and ammonium lauroyl carboxylate. Anionic fluorosurfactants may also be used.

Other anionic materials include natural soaps derived from saponification of vegetable and / or animal fats & oils, examples of which include sodium laurate, sodium myristate, palmitate, stearate, talo weight, cocoate.

Any mating cation M can be used on the anionic surfactant. Preferably the counter cation is selected from the group consisting of sodium, potassium, ammonium, monoethanolamine, diethanolamine and triethanolamine. More preferably, the counter cation is ammonium.

Nonionic foam forming surfactant

Non-limiting examples of nonionic foam forming surfactants for use in the compositions of the present invention are described in McCutcheon's, Detergents and Emulsifiers , North American edition (1986), allured Publishing Corporation publication; And McCutcheon's, Functional Materials , North American edition (1992), both of which are incorporated herein by reference.

Nonionic foam-forming surfactants useful herein include those selected from the group consisting of alkyl glucosides, alkyl polyglucosides, polyhydroxy fatty acid amides, alkoxylated fatty acid esters, sucrose esters, amine oxides, and mixtures thereof.

Alkyl glucosides and alkyl polyglucosides are useful herein and are broadly defined as condensation products of long chain alcohols, such as C8-C30 alcohols, with sugars or starches or sugar polymers or starch polymers, i.e. glycosides or polyglycosides . Of the above compounds can be expressed (equation by the formula (S) _n -OR, S is a sugar moiety such as glucose, fructose, mannose and galactose, and; n is an integer from about 1 to about 1000, and; R is a C8- 30 alkyl group). Examples of the long chain alcohol from which the alkyl group may be derived include decyl alcohol, cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol, oleyl alcohol and the like. Preferred examples of such surfactants include those wherein S is a glucose moiety, R is a C8-20 alkyl group, and n is an integer from about 1 to about 9. Examples of commercially available surfactants include decyl polyglucoside (commercially available as APG 325 CS from Henkel) and lauryl polyglucoside (available as APG 600CS and 625 CS from Henkel). In addition, sucrose ester surfactants such as sucrose cocoate and sucrose laurate are useful.

Other useful nonionic surfactants include polyhydroxy fatty acid amide surfactants, more specific examples of which include glucosamides corresponding to the following formula:

Wherein R ¹ is H, C ₁ -C ₄ alkyl, 2-hydroxyethyl, 2-hydroxypropyl, preferably C ₁ -C ₄ alkyl, more preferably methyl or ethyl, Methyl, R ² is C ₅ -C ₃₁ alkyl or alkenyl, preferably C ₇ -C ₁₉ alkyl or alkenyl, more preferably C ₉ -C ₁₇ alkyl or alkenyl, most preferably C ₁₁ - C ₁₅ alkyl or alkenyl; Z is a polyhydroxy hydrocarbyl moiety or misfire thereof alkoxyl having a linear hydrocarbyl chain with at least 3 hydroxyl directly connected to the chain (preferably ethoxylated or propoxylated Derivative) derivative). Z is preferably a sugar moiety selected from the group consisting of glucose, fructose, maltose, lactose, galactose, mannose, xylose, and mixtures thereof. Particularly preferred surfactants corresponding to the above structures are coconut alkyl N-methyl glucoside amides (i.e., the R ² CO- moiety is derived from coconut oil fatty acids). Processes for the preparation of compositions comprising polyhydroxy fatty acid amides are described, for example, in British Patent Application 809,060 (published Feb. 18, 1959, Thomas Hedley & Co., Ltd.); U.S. Patent No. 2,965,576 (granted to ER Wilson on December 20, 1960); U.S. Patent No. 2,703,798 (issued to AM Schwartz on Aug. 3, 1955) and U.S. Patent No. 1,985,424 (issued to Piggott on December 25, 1934), each of which is incorporated herein by reference in its entirety .

Other examples of nonionic surfactants include amine oxides. Amine oxides correspond to the formula R ₁ R ₂ R ₃ N → O wherein R ₁ is an alkyl, alkenyl, or monohydroxyalkyl radical of about 8 to about 18 carbon atoms, 0 to about 10 ethylene oxide And from 0 to about 1 glyceryl moiety, wherein R ₂ and R ₃ are independently selected from the group consisting of about 1 to about 3 carbon atoms and from 0 to about 1 hydroxyl group, such as methyl, ethyl, propyl, The arrows in the formulas are typical signs of semi-polar bonding. Examples of amine oxides suitable for use in the present invention include dimethyl-dodecylamine oxide, oleyldi (2-hydroxyethyl) amine oxide, dimethyloctylamine oxide, dimethyl-decylamine oxide, dimethyltetradecyl (2-hydroxyethyl) -tetradecylamine oxide, 2-dodecoxyethyldimethylamine oxide, 3-dodecoxy 2-hydroxypropyl di (3-hydroxypropyl) amine oxide, and dimethylhexadecylamine oxide.

Non-limiting examples of preferred nonionic surfactants for use herein include C8-C14 glucose amide, C8-C14 alkyl polyglucoside, sucrose cocoate, sucrose laurate, laurylamine oxide, cocoamine oxide, And mixtures thereof.

Cationic foam-forming surfactant

Cationic foam forming surfactants are also useful in the articles of the present invention. Suitable cationic foam forming surfactants include, but are not limited to, fatty amines, 2-fatty quaternary amines, 3-fatty quaternary amines, imidazolinium quaternary amines, and combinations thereof. Suitable fatty amines include monoalkyl quaternary amines such as cetyltrimethylammonium bromide. Suitable quaternary amines include dialkylamidoethylhydroxyethylmonium methosulfate. However, fatty amines are preferred. When the cationic foam-forming surfactant is the main foaming surfactant of the cleansing component, it is preferred to use a foam-forming enhancer. Additionally, nonionic surfactants have been found to be particularly useful in combination with the cationic foam forming surfactants.

Amphoteric foam forming surfactant

The term " zwitterionic foam forming surfactant " as used herein is intended to also include zwitterionic surfactants well known to those skilled in the art as a class of amphoteric surfactants.

A wide variety of amphoteric foam forming surfactants may be used in the compositions of the present invention. It is preferable that the aliphatic radical is branched or straight chain and one of the radicals is an ionizable water-soluble group, for example, a carboxy, a sulfonate , Sulfate, phosphate or phosphonate are particularly useful.

Non-limiting examples of ampholytic surfactants useful in compositions of the present invention are described in McCutcheon's, Detergents and Emulsifiers , North American edition (1986), allured Publishing Corporation publication; And McCutcheon ' s, Functional Materials , North American Edition (1992), both of which are incorporated herein by reference.

Non-limiting examples of zwitterionic or zwitterionic surfactants include those selected from the group consisting of betaines, sultaines, hydroxysultaines, alkyliminoacetates, iminodialcanoates, aminoalkanoates, and mixtures thereof There are things.

Examples of betaine include higher alkyl betaines such as cocodimethylcarboxymethylbetaine, lauryldimethylcarboxymethylbetaine, lauryldimethylcarboxyethylbetaine, cetyldimethylcarboxymethylbetaine, cetyldimethylbetaine (available from Lonza Corp. Carboxypropyl betaine, lauryl bis- (2-hydroxypropyl) alpha-carboxyethyl betaine, commercially available as Lonzaine 16SP), lauryl bis- (2-hydroxyethyl) carboxymethyl betaine, oleyl dimethyl gamma- (2-hydroxyethyl) sulfopropyl betaine, amidobetaine and amidosulfobetaine, wherein the radicals are selected from the group consisting of RCONH (CH ₂ ) ₃ radicals such as cocodimethylsulfopropylbetaine, lauryldimethylsulphoethylbetaine, laurylbis Oleyl betaine (available from Henkel as bilaterally available in Velvetex OLB-50) and cocamidopropyl betaine (available from Henkel as Velvetex BK-35 and BA-35) .

Examples of sultaines and hydroxysulfates include materials such as cocamidopropylhydroxysultaine (available as Mirataine CBS from Rhone-Poulenc).

Zwitterionic surfactants having the following formula are preferred for use herein:

Wherein R ¹ is an unsubstituted, saturated or unsaturated, straight chain or branched chain alkyl of from about 9 to about 22 carbon atoms, R ¹ preferably has from about 11 to about 18 carbon atoms, more preferably from about 12 to about More preferably from about 14 to about 18 carbon atoms, m is an integer from 1 to about 3, more preferably from about 2 to about 3, more preferably about 3, and n is 0 or 1 , Preferably 1, R ² and R ³ are independently selected from the group consisting of alkyl groups of 1 to about 3 carbon atoms, unsubstituted or mono-substituted by hydroxy, preferred R ² and R ³ are CH ₃ X is selected from the group consisting of CO ₂ , SO ₃ and SO ₄ ; R ⁴ is selected from the group consisting of saturated or unsaturated, linear or branched alkyl, unsubstituted or monosubstituted with hydroxy, of 1 to about 5 carbon atoms Lt; / RTI > When X is CO ₂ , R ⁴ is preferably 1 or 3 carbon atoms, more preferably 1 carbon atom. When X is SO ₃ or SO ₄ , R ⁴ is preferably about 2 to about 4 carbon atoms, preferably 3 carbon atoms.

Examples of amphoteric surfactants of the present invention include the following compounds:

Cetyldimethylbetaine (the material also has cetyl betaine as CTFA designation):

Cocamidopropyl Betaine:

(Wherein R is about 9 to about 13 carbon atoms)

Cocamidopropyl hydroxysulphate:

*

(Wherein R is about 9 to about 13 carbon atoms).

Examples of other useful zwitterionic surfactants include those of the formula RN [(CH ₂ ) _m CO ₂ M] ₂ and RNH (CH ₂ ) _m CO ₂ M, wherein m is 1 to 4 and R is a C _{8- C22} alkyl or alkenyl, and M is H, an alkali metal, an alkaline earth metal ammonium or an alkanol ammonium, an alkyliminoacetate and an iminodialkanoate. Also included are imidazolidinium and ammonium derivatives. Specific examples of suitable zwitterionic surfactants include sodium 3-dodecyl-aminopropionate, sodium 3-dodecylaminopropanesulfonate, N-higher alkyl aspartic acids such as those described in U.S. Patent No. 2,438,091, Quot ;, incorporated herein by reference); And products sold under the trademark " Miranol ", as described in U.S. Patent No. 2,528,378 (the full text of which is incorporated herein by reference). Other examples of useful zwitterionic surfactants include zwitterionic phosphates such as cocamidopropyl PG-dimonium chloride phosphate (available from Mona Corp. as Monaquat PTC). Also useful are amphoacetates such as disodium lauroamphodiacetate, sodium lauroamphoacetate and mixtures thereof.

Preferred foaming surfactants are selected from the group consisting of:

Sodium laureth sulfate, ammonium laureth sulfate, sodium laureth sulfate, sodium laureth sulfate, sodium laureth sulfate, ammonium laureth sulfate, sodium laurel sulfate, ammonium lauryl sulfate, sodium lauryl sulfate, Sodium cocoyl isethionate, sodium lauroyl isethionate, sodium cetyl sulfate, sodium monolauryl phosphate, sodium coco glyceryl ether sulphonate, sodium C ₉ -C ₂₂ soap, and combinations thereof. Anionic foaming surfactant selected from the group consisting of; A nonionic foam-forming surfactant selected from the group consisting of laurylamine oxide, cocoamine oxide, decylpolyglucose, lauryl polyglucose, sucrose cocoate, C12-14 glucosamides, sucrose laurate, and combinations thereof ; A cationic foam-forming surfactant selected from the group consisting of fatty amines, 2-fatty quaternary amines, 3-fatty quaternary amines, imidazolinium quaternary amines, and combinations thereof; Zwitterionic surfactant selected from the group consisting of disodium lauroamphoacetate, sodium lauroamphoacetate, cetyldimethylbetaine, cocoamidopropyl betaine, cocoamidopropylhydroxysultaine, and combinations thereof.

Therapeutic Efficacy Component

In certain embodiments of the present invention, the article essentially comprises a therapeutic efficacy component. The efficacious ingredient is placed in the vicinity of the water-insoluble substrate and comprises from about 10% to about 1000%, more preferably from about 10% to about 500%, most preferably from about 10% Approximately 250% by weight of the therapeutic agent is included. Preferably, the therapeutic agent is selected from the group consisting of a hydrophobic conditioning agent, a hydrophilic conditioning agent, a structured conditioning agent, and combinations thereof.

Hydrophobic conditioning agent

The articles of the invention may include one or more hydrophobic conditioning agents useful for providing conditioning efficacy to the skin or hair during use of the article. The articles of the invention preferably contain from about 0.5% to about 1,000%, more preferably from about 1% to about 200%, and most preferably from about 10% to about 100% by weight of the water insoluble substrate Hydrophobic conditioning agents are included.

The hydrophobic conditioning agent may be selected from one or more hydrophobic conditioning agents such that the weighted arithmetic mean solubility parameter of the hydrophobic conditioning agent is 10.5 or less. Based on the mathematical definition of the solubility coefficient, for example, for a hydrophobic conditioning agent comprising two or more compounds, one of the compounds has an individual solubility coefficient of greater than 10.5, and the required weight, i.e., 10.5 or less, It is recognized that it is possible to achieve an arithmetic mean solubility coefficient.

Solubility factors are well known to those of skill in the art of formulations and are conventionally used as a guide for determining the compatibility and solubility of a substance in a formulation process.

The solubility parameter, delta, of a chemical compound is defined as the square root of the aggregation energy density of the compound. Typically, the solubility coefficient for a compound is calculated from the tabulated values of the adduct contribution to the heat of vaporization and molar volume of the components of the compound using the following formula:

(Where Σ _i E _i = sum of contribution of evaporation heat additions, and Σ _i m _i = sum of mole volume contribution).

Standard values for the evaporation heat and mole volumetric contribution of various atomic and paramagnetic fluids are described in Barton, AFM, Handbook of Solubility Parameters , CRC Publishing, Chapter 6, Table 3, pp. 64-66 (1985), the entire contents of which are incorporated herein by reference. The solubility coefficient formula is described in Fedors, RF, " A Method for Estimating Both Solubility Parameters and Molar Volumes of Liquids ", Polymer Engineering and Science, vol. 14, no. 2, pp. 147-154 (1974. 2), the entire contents of which are incorporated herein by reference.

The solubility coefficient follows the law of the mixture that the solubility coefficient of a substance mixture is given by the weighted arithmetic mean (ie, weighted average) of the solubility coefficient of each component of the mixture. Which is incorporated herein by reference, in Handbook of Chemistry and Physics , 57th Edition, CRC Publishing, p. C-726 (1976-1977).

Formulation chemists typically report and use solubility coefficients in units of (㎈ / ㎤) ^1/2 . In the Handbook of Solubility Parameters , the values in the table for the contribution of evaporation heat are reported in kJ / ㏖ units. However, the vaporization heat values listed in the table are readily converted to ㎈ / ㏖ using the following well-known formulas:

1 J / ㏖ = 0.239006 ㎈ / ㏖ and 1000 J = 1 kJ

The Gordon, AJ et al., The Chemist's Companion , John Wiley & Sons, pp. 456-463 (1972).

Solubility coefficients for a wide variety of chemicals are also listed in the table. A table of solubility coefficients is given in the Handbook of Solubility Parameters mentioned above. See also, " Solubility Effects In Product, Package, Penetration, And Preservation ", CD Vaughan, Cosmetics and Toiletries, vol. 103, 1988. 10., pp. 47-69].

Non-limiting examples of hydrophobic conditioning agents include mineral oils, petrolatum, lecithin, hydrogenated lecithin, lanolin, lanolin derivatives, C7-C40 branched hydrocarbons, C1-C30 alcoholic esters of C1-C30 carboxylic acids, C2-C30 dicarboxylic A C1-C30 alcoholic ester of an acid, a monoglyceride of a C1-C30 carboxylic acid, a diglyceride of a C1-C30 carboxylic acid, a triglyceride of a C1-C30 carboxylic acid, an ethylene glycol monoester of a C1- Ethylene glycol diesters of -C30 carboxylic acids, propylene glycol monoesters of C1-C30 carboxylic acids, propylene glycol diesters of C1-C30 carboxylic acids, C1-C30 carboxylic acid monoesters and polyesters of sugars, Polyalkylarylsiloxanes, cyclomethicone of 3 to 9 silicon water, vegetable oils, hydrogenated vegetable oils, polypropylene glycol C4-C20 alkyl ethers, Di-C8-C30 alkyl ethers, and combinations thereof.

Mineral oil, also known as petrolatum liquid, is a mixture of liquid hydrocarbons obtained from petroleum. Which is incorporated herein by reference in its entirety, The Merck Index, 10th Edition, Entry 7048, p. 1033 (1983) and International Cosmetic Ingredient Dictionary, 5th Edition, vol. 1, p. 415-417 (1993).

Petrolatum, also known as petroleum jelly, is a colloidal system of non-linear solid hydrocarbons and high boiling liquid hydrocarbons, of which most liquid hydrocarbons are trapped in the micelles. Which is incorporated herein by reference in its entirety, The Merck Index, 10th Edition, Entry 7047, p. 1033 (1983); Schindler, Drug. Cosmet. Ind. , 89 , 36-37, 76, 78-80, 82 (1961); And International Cosmetic Ingredient Dictionary, 5th Edition, vol. 1, p. 537 (1993).

Lecithin is also useful as a hydrophobic conditioning agent. This is a naturally occurring mixture of diglycerides of certain fatty acids linked to a choline ester of phosphoric acid.

Straight chain and branched chain hydrocarbons of about 7 to about 40 carbon atoms are useful herein. Non-limiting examples of the hydrocarbon materials include dodecane, isododecane, squalane, cholesterol, hydrogenated polyisobutylene, docosane acid (i.e., C ₂₂ hydrocarbon), hexadecane, iso-hexadecane (from Presperse (South Plainfield, NJ) Permethyl ≪ RTI ID = 0.0 > 101A < / RTI > Also useful are C7-C40 isoparaffins, which are C7-C40 branched hydrocarbons. Polydecene, a branched chain hydrocarbon, is also useful herein and is commercially available from Mobile Chemical (Edison, NJ) under the trade name PureSyn 100 And Puresyn 3000 Lt; / RTI >

Also useful are C1-C30 carboxylic acid and C1-C30 alcoholic esters of C2-C30 dicarboxylic acids, including straight and branched chain materials as well as aromatic derivatives. It is also possible to use esters such as monoglycerides of C1-C30 carboxylic acids, diglycerides of C1-C30 carboxylic acids, triglycerides of C1-C30 carboxylic acids, ethylene glycol monoesters of C1-C30 carboxylic acids, Ethylene glycol diesters of acids, propylene glycol monoesters of C1-C30 carboxylic acids and propylene glycol diesters of C1-C30 carboxylic acids are useful. Straight chain, branched chain and arylcarboxylic acid. Also propoxylated and ethoxylated derivatives of these materials are useful. Non-limiting examples include diisopropyl sebacate, diisopropyl adipate, isopropyl myristate, isopropyl palmitate, myristyl propionate, ethylene glycol distearate, 2-ethylhexyl palmitate, isodecyl neopentano Octyl maleate, di-2-ethylhexyl maleate, cetyl palmitate, myristyl myristate, stearyl stearate, cetyl stearate, behenyl behenate, dioctyl maleate, dioctyl sebacate, diisopropyl adipate, Caprylic / capric triglyceride, PEG-6 caprylic / capric triglyceride, PEG-8 caprylic / capric acid triglyceride, and combinations thereof do.

Various C1-C30 monoesters and polyesters of sugars and related substances are also useful. The esters are derived from a sugar or polyol moiety and one or more carboxylic acid moieties. Depending on their constitutional dispersions and sugars, the ester may be in the form of a liquid or solid at room temperature. Examples of liquid esters include: glucose tetraoleate, glucose tetraester of soybean oil fatty acid (unsaturated), mannose tetraester of mixed soybean fatty acid, galactose tetraester of oleic acid, arabinose tetraester of linoleic acid, xylose Sucrose stearate, tetra linoleate, galactose pentaoleate, sorbitol tetraoleate, sorbitol hexaester of unsaturated soybean oil fatty acid, xylitol pentaoleate, sucrose tetraoleate, sucrose pentaoleate, sucrose hexaoleate, sucrose heptaoleate, sucrose Octaoleate and mixtures thereof. Examples of solid esters include: sorbitol hexaesters in which the carboxylic acid ester moiety is palmitoleate and arachidate in a 1: 2 molar ratio; Octaesters of raffinose wherein the carboxylic acid ester moiety is linoleate and behenate in a 1: 3 molar ratio; A hepta ester of maltose, a sunflower seed oil fatty acid and a lignocerate having an esterified carboxylic acid moiety of 3: 4 molar ratio; Octaesters of sucrose in which the esterified carboxylic acid moiety is an oleate of 2: 6 molar ratio and behenate; And an octaester of sucrose wherein the esterified carboxylic acid moiety is laurate, linoleate and behenate in a 1: 3: 4 molar ratio. Preferred solid materials are sucrose polyesters having an esterification degree of 7-8, a fatty acid moiety C18 mono- and / or di-unsaturated and behenic, and an unsaturated: behenic molar ratio of 1: 7 to 3: 5 . Particularly preferred solid sugar polyesters are sucrose octaesters having about 7 behenic fatty acid moieties and about 1 oleic acid moiety in the molecule. Other substances include cottonseed oil or soybean oil fatty acid esters of sucrose. The ester material is described in U.S. Patent No. 2,831,854, U.S. Patent No. 4,005,196 (granted to Jandacek on Jan. 1, 1977); U.S. Patent No. 4,005,195 (granted to Jandacek on January 25, 1977), U.S. Patent No. 5,306,516 (granted to Letton et al. On Apr. 26, 1994); U.S. Patent No. 5,306,515 issued to Letton et al. On March 26, 1994; U.S. Patent No. 5,305,514 issued to Letton et al. On March 26, 1994; U.S. Patent No. 4,797,300 to Jandacek et al. U.S. Patent No. 3,963,699 issued to Rizzi et al. On June 15, 1976; U.S. Patent No. 4,518,772 issued to Volpenhein on May 21, 1985; And U.S. Patent No. 4,517,360 to Volpenhein on May 21, 1985, each of which is incorporated herein by reference in its entirety.

Nonvolatile silicones such as polydialkylsiloxanes, polydialylsiloxanes and polyalkarylsiloxanes are also useful oils. These silicones are disclosed in U.S. Patent No. 5,069,897 (issued to Orr on December 3, 1991), which is incorporated herein by reference in its entirety. The polyalkylsiloxane corresponds to the formula R ₃ SiO [R ₂ SiO] _x SiR ₃ wherein R is an alkyl group (preferably R is methyl or ethyl, more preferably methyl), x is the desired molecular weight An integer of about 500 or less selected to obtain). Commercially available polyalkylsiloxanes include polydimethylsiloxanes, also known as dimethicone, and non-limiting examples include Vicasil sold by General Electric Company Series and Dow Corning sold by Dow Corning Corporation 200 series. Specific examples of polydimethylsiloxanes useful herein include Dow Corning, having a viscosity of 10 centistoke and a boiling point of greater than 200 < RTI ID = 0.0 > 225 < / RTI > fluids, and Dow Corning < RTI ID = 0.0 > 200 < / RTI > Also useful are materials such as trimethylsiloxysilicate, which is a polymeric material corresponding to the formula [(CH ₂ ) ₃ SiO _1/2 ] _x [SiO ₂ ] _y , where x is an integer from about 1 to about 500 And y is an integer from about 1 to about 500). Commercially available trimethylsiloxysilicates include Dow Corning, a mixture with dimethicone 593 fluids. Dimethicol, a hydroxy-terminated dimethyl silicone, is also useful herein. The material can be represented by the formula R ₃ SiO [R ₂ SiO] _x SiR ₂ OH and HOR ₂ SiO [R ₂ SiO] _x SiR ₂ OH wherein R is an alkyl group (preferably R is methyl or ethyl , More preferably methyl), and x is an integer of about 500 or less selected to obtain the desired molecular weight. Commercially available dimethiconols are typically formulated with a mixture of dimethicone or cyclomethicone (e.g., Dow Corning 1401, 1402 and 1403 fluids). Polyalkylarylsiloxanes are also useful herein and are preferably polymethylphenylsiloxanes having a viscosity of from about 15 to about 65 centistokes at 25 占 폚. These materials are commercially available, for example, as SF 1075 methylphenyl fluids (sold by General Electric Company) and 556 cosmetic grade phenyl trimethicone fluids (sold by Dow Corning Corporation). Alkylated silicones such as methyldecylsilicon and methyloctylsilicon are also useful herein and are commercially available from the General Electric Company. Also useful are alkyl modified siloxanes such as alkyl methicone and alkyl dimethicone, wherein the alkyl chain has from 10 to 50 carbon atoms. The siloxane is marketed under the trade name ABIL WAX 9810 (C ₂₄ -C ₂₈ alkyl methicone) (sold by Goldschmidt) and SF 1632 (cetearyl methicone) (sold by General Electric Company).

Vegetable oils and hydrogenated vegetable oils are also useful herein. Examples of vegetable oils and hydrogenated vegetable oils include safflower oil, castor oil, coconut oil, cottonseed oil, menhaden oil, palm oil, palm oil, peanut oil, soybean oil, rapeseed oil, flaxseed oil, Hydrogenated coconut oil, hydrogenated cottonseed oil, hydrogenated cottonseed oil, hydrogenated palm oil, hydrogenated palm oil, hydrogenated palm oil, hydrogenated peanut oil, hydrogenated soybean oil, hydrogenated rapeseed oil, hydrogenated flaxseed oil, hydrogenated oil, sesame oil, sunflower seed oil, hydrogenated safflower oil, hydrogenated castor oil, hydrogenated coconut oil, Rice bran oil, hydrogenated sesame oil, hydrogenated sunflower seed oil, and mixtures thereof.

C4-C20 alkyl ethers of polypropylene glycol, C1-C20 carboxylic acid esters of polypropylene glycol, and di-C8-C30 alkyl ethers are also useful herein. Non-limiting examples of such materials include PPG-14 butyl ether, PPG-15 stearyl ether, dioctyl ether, dodecyl octyl ether, and mixtures thereof.

Hydrophobic chelating agents are also useful as hydrophobic conditioning agents. Suitable agents are described in U.S. Patent No. 4,387,244 (issued to Scanlon et al. On Jun. 7, 1987) and co-pending U.S. Patent Application Serial Nos. 09 / 258,747 and 09 / 259,485 (Schwartz et al. Application.

Hydrophilic conditioning agent

The article of the present invention may optionally include one or more hydrophilic conditioning agents. Non-limiting examples of hydrophilic conditioning agents include polyhydric alcohols, polypropylene glycols, polyethylene glycols, urea, pyrrolidonecarboxylic acids, ethoxylated and / or propoxylated C3-C6 diols and triols, alpha-hydroxy C2-C6 Carboxylic acids, ethoxylated and / or propoxylated sugars, polyacrylic acid copolymers, sugars of up to about 12 carbon atoms, sugar alcohols of up to about 12 carbon atoms, and mixtures thereof. Specific examples of useful hydrophilic conditioning agents include urea; Guanidine; Glycolic acid and glycolate salts (e.g., ammonium and quaternary alkylammonium); Lactic acid and lactate salts (e. G., Ammonium and quaternary alkylammonium); Sucrose, fructose, glucose, eruthrose, erythritol, sorbitol, mannitol, glycerol, hexanetriol, propylene glycol, butylene glycol, hexylene glycol and the like; PPG-12, PPG-15, PPG-20, PPG-26, PPG-15, PPG- -30, PPG-34; Alkoxylated glucose; Hyaluronic acid; Cationic skin conditioning polymers (e. G., Quaternary ammonium polymers such as polyquaternium polymers); And mixtures thereof. In particular, glycerol is a preferred hydrophilic conditioning agent for the articles of the present invention. In addition, various optional forms of aloe vera (e. G., Aloe vera gel), chitosan and chitosan derivatives such as chitosan lactate, lactamid monoethanolamine; Acetamide monoethanolamine; And mixtures thereof are also useful. Propoxylated glycerol as disclosed in U.S. Patent No. 4,976,953 (to Orr et al., Issued December 12, 1990) is also useful, and is incorporated herein by reference in its entirety.

Therapeutic efficacy components can be prepared in various forms. In one embodiment of the invention, the therapeutic efficacy component is in the form of an emulsion. For example, oil-in-water, water-in-oil, water in water, and water-in-oil emulsions in silicone emulsions are useful herein. The term " water " used in connection with the emulsion may mean water-miscible materials such as water-soluble or glycerin as well as water.

Preferred therapeutic efficacy components include emulsions further comprising an aqueous phase and an oil phase. As will be appreciated by those skilled in the art, the components provided will be predominantly distributed within the water or oil phase depending on the solubility / dispersibility of the therapeutic agonist in the composition. In one embodiment, the oil phase includes one or more hydrophobic conditioning agents. In another embodiment, the aqueous phase comprises at least one hydrophilic conditioning agent.

Therapeutically efficacious ingredients of the present invention, which are in emulsion form, generally include an aqueous and oily or lipid phase. Suitable oils or lipids may be derived from animals, plants or petroleum, and may be natural or synthetic (i.e., artificial). Such oils are discussed above in the section on hydrophobic conditioning agents. Suitable aqueous phase ingredients include the hydrophilic conditioning agents discussed above. Preferred emulsion forms include water-in-oil emulsions, water-in-silicone emulsions and other reversed phase emulsions. Additionally, preferred emulsions also include hydrophilic conditioning agents such as glycerin to produce an oil-in-water glycerin emulsion.

The therapeutic efficacy component in the emulsion form will preferably further comprise an emulsifier in an amount of from about 1% to about 10%, more preferably from about 2% to about 5%, by weight of the therapeutic efficacy component. The emulsifier may be non-ionic, anionic or cationic. Suitable emulsifying agents are described, for example, in U.S. Patent No. 3,755,560 to Dickert et al. U.S. Patent No. 4,421,769 issued to Dixon et al. And McCutcheon ' s Detergents and Emulsifiers , North American Edition, p. 317-324 (1986). Therapeutic efficacy components in the form of emulsions may also include defoamers to minimize foam formation upon application to the skin. Defoaming agents include high molecular weight silicones and other materials well known in the art for such applications.

The therapeutic efficacy component may also be in the form of a microemulsion. As used herein, "microemulsion" refers to a thermodynamically stable mixture of two immiscible solvents (one non-polar and one polar) stabilized by a surfactant that is a cationic molecule. Preferred microemulsions include water-in-oil microemulsions.

Structured conditioning agent

The therapeutic efficacy component may include a structured conditioning agent. Suitable structured conditioning agents include, but are not limited to, vesicular structures such as ceramides, liposomes, and the like.

In another embodiment, the therapeutically agonist of the potentiator is included in the coacervate forming composition. Preferably, the coacervate-forming composition includes a cationic polymer, an anionic surfactant, and a dermatologically acceptable carrier for the polymer and the surfactant. The cationic polymer is selected from the group consisting of a quaternary ammonium polymer of a natural backbone, a quaternary ammonium polymer of a synthetic backbone, a natural backbone both cationic type polymer, a synthetic backbone both cationic type polymer, and combinations thereof .

More preferably, the cationic polymer is selected from the group consisting of polyquaternium-4, polyquaternium-10, polyquaternium-24, PG-hydroxyethylcellulose alkyldimonium chloride, guar hydroxypropyl trimonium chloride, A natural backbone quaternary ammonium polymer selected from the group consisting of hydroxypropyltrimonium chloride and combinations thereof; Polyquaternium-11, polyquaternium-16, polyquaternium-17, polyquaternium-18, polyquaternium-28, polyquaternium- Poly-quaternium-32, polyquaternium-37, polyquaternium-43, polyquaternium-44, polyquaternium-46, polymethacrylamidopropyltrimonium chloride, acrylamidopropyltrimonium chloride / acrylamide copolymer And synthetic quaternary ammonium polymers selected from the group consisting of combinations thereof; Natural backbone amphoteric polymers selected from the group consisting of chitosan, quaternized proteins, hydrolyzed proteins and combinations thereof; Polyquaternium-22, polyquaternium-39, polyquaternium-47, adipic acid / dimethylaminohydroxypropyldiethylenetriamine copolymer, polyvinylpyrrolidone / dimethylaminoethyl methacrylate copolymer, Vinyl caprolactam / polyvinylpyrrolidone / dimethylaminoethyl methacrylate copolymer, nonylcaprolactam / polyvinylpyrrolidone / dimethylaminopropyl methacrylamide terpolymer, polyvinylpyrrolidone / dimethylaminopropyl methacrylate copolymer Amide copolymers, polyamines, and combinations thereof, both of which are cationic type polymers; And combinations thereof. More preferably, the cationic polymer is a cationic type polymer of both sides of the synthetic backbone. Even more preferably, the cationic polymer is a polyamine.

When the cationic polymer is a polyamine, it is preferred that the cationic polyamine polymer is selected from the group consisting of polyethyleneimine, polyvinylamine, polypropyleneimine, polylysine, and combinations thereof. Even more preferably, the cationic polyamine polymer is a polyethyleneimine.

In certain embodiments in which the cationic polymer is a polyamine, the polyamine may be modified to be hydrophobic or hydrophilic. In this case, the cationic polyamine polymer is selected from the group consisting of benzylated polyamines, ethoxylated polyamines, propoxylated polyamines, alkylated polyamines, amidated polyamines, esterified polyamines, and combinations thereof. The coacervate- From about 0.01% to about 20%, more preferably from about 0.05% to about 10%, and most preferably from about 0.1% to about 5% by weight of the cationic polymer.

Suitable anionic surfactants include those mentioned above in connection with " cleansing ingredients ". Preferably, in the case of a coacervate forming composition, the anionic surfactant is selected from the group consisting of sarcosinate, glutamate, sodium alkyl sulfate, ammonium alkyl sulfate, sodium alkylate sulfate, ammonium alkylate sulfate, ammonium laureth- Sulphate, sodium sulphate, sodium sulphate, sodium sulphate, sodium sulphate, sodium sulphate, sodium sulphate, sodium sulphate, sodium sulphate, More preferably, the anionic surfactant is selected from the group consisting of sodium lauroyl sarcosinate, monosodium lauroyl glutamate, sodium alkyl sulfate, ammonium alkyl sulfate, sodium alkylate sulfate, ammonium alkylate sulfate and combinations thereof ≪ / RTI >

Suitable coacervate-forming compositions are disclosed in co-pending U. S. Patent Application Serial No. 09 / 397,747, filed September 15, 1999 (Schwartz et al.); 09 / 397,746 (filed by Heinrich et al.); 09 / 397,712 (filed by Schwartz et al.); 09 / 397,723 (filed by Heinrich et al.); And 09 / 397,722 (filed by Venkitaraman et al.).

Alternatively, the coacervate-forming composition can include an anionic polymer, a cationic surfactant, and a dermatologically acceptable carrier for the polymer and the surfactant. The anionic polymer may be selected from the group consisting of polyacrylic acid polymers, polyacrylamide polymers, copolymers of acrylic acid, acrylamide and other natural or synthetic polymers (e.g., polystyrene, polybutene, polyurethane, etc.) Lt; / RTI > Suitable rubbers include alginates (e.g., propylene glycol alginate), pectin, chitosan (e.g., chitosan lactate) and modified rubbers (e.g., starch octenyl succinate) and combinations thereof. More preferably, the anionic polymer is selected from the group consisting of polyacrylic acid polymers, polyacrylamide polymers, pectin, chitosan, and combinations thereof. Preferred articles of the present invention include an anionic < RTI ID = 0.0 > (I) < / RTI > Polymers. Suitable cationic surfactants include, but are not limited to those discussed herein.

The therapeutic efficacy component of the article may be selected from the group consisting of an anti-acne agent, an anti-wrinkle agent, an antibacterial agent, an antifungal agent, an antiinflammatory agent, a local anesthetic agent, an artificial tanning agent and an accelerator, an antiviral agent, By depositing various materials on the skin or hair surface, including, but not limited to, < RTI ID = 0.0 > and / or < / RTI >

Therapeutic efficacious ingredients may be included within the cleansing ingredients of the present invention or, conversely, should be understood as being able to form one ingredient with the ingredients that are not distinguished.

Multi-article implementation example

The article of the present invention may also be packaged individually or packaged with an additional article suitable for providing a separate effect, e.g., aesthetic, therapeutic, functional or other efficacy not provided by the primary article, such that the personal care kit . Additional articles of the personal care kit preferably include a foam-forming surfactant-containing cleansing component or therapeutic efficacy component that is placed or embedded on a substrate layer of a water-insoluble substrate and an additional article comprising one or more layers do.

Additional articles of the invention will also provide functional efficacy that is added to or in place of therapeutic or aesthetic efficacy. In this case, the additional ingredients may be useful as a drying tool suitable for use in helping to remove water from the skin or hair upon completion of a shower or bath.

Surface saturation ratio measurement method

An article of the invention comprising a therapeutic efficacy component has a therapeutic efficacy component substantially on the surface of the substrate. By "substantially on the surface of the substrate" is meant that the surface saturation ratio is greater than about 1.25, preferably greater than about 1.5, more preferably greater than about 2.0, even more preferably greater than about 2.25, and most preferably greater than 2.5 it means. The surface saturation ratio is a measure of the agonist on the surface of the substrate. The measurement is obtained with an Attenuated Total Reflectance (ATR) FT-IR spectrometer whose use is well known to those skilled in the art of analytical chemistry.

Many conventional methods of applying a conditioning agent to a substrate employ process and / or product rheology unsuitable for the purposes of the present invention. For example, if a conditioning agent is applied to the entire substrate in a so-called "dip and nip" process, which is a process of immersing the substrate in a fluid bath of the conditioning agent and then pressing the substrate web through the metering roll, No effective direct delivery opportunity of the composition out of the fabric and other surfaces during use is obtained. In addition, many of the inventive articles provide effective overall body benefits using a conditioning agent with a sufficient load on the substrate, typically requiring a loading rate of about 100-200 wt% based on the dry substrate. Known personal care tools utilizing such high load levels essentially avoid contact with aesthetic issues that may arise from such high loads by uniformly distributing the load across the substrate, including inside the substrate. Applicants have surprisingly found that a high-load conditioning agent can be retained on the surface of an article and thus advantageously improved during the use of the composition of the present invention, while the opportunity of direct delivery of the agonist from the substrate to the surface to be treated can be obtained. Gt; aesthetic agent < / RTI >

The procedure for the measurement is as follows:

Instrument Setup: Infrared spectra are collected using a BioRad FTS-7 spectrometer manufactured by BioRad Labs (Digital Laboratory Division; Cambridge, Mass.). Typically, the measurement consists of 100 scans at a resolution of 4 cm ^-1 . The collection optics are Graseby Specac, Inc. (Located in Fairfield, CT) with a 60 degree ZnSe ATR crystal. Data are collected at 25 ° C and analyzed using Grams 386 software distributed at Galactic Industries Corp. (located in Salem, NH). Prior to measurement, the crystals are washed with a suitable solvent. The specimen is placed on the ATR crystal and held under a constant 4 kg weight.

Experimental procedure:

(1) Measure the reference (background) spectrum of the washed and air dried cell.

(2) First, the substrate to which the agonist is not applied is selected, and the selected substrate includes the outer surface of the article. The substrate is placed on top of the ATR crystal so that the crystal is in contact with the outer surface. First, place the substrate flat on the measuring platform. Thereafter, a weight of 4 kg is placed on top of the substrate. The spectrum is then measured (typically 100 scans at 4 cm ^-1 resolution). Since the absorbance of the substrate alone is ascertained, the substrate serves as an internal standard. Identify major substrate peaks and wavelengths.

(3) Repeat the above procedure for the substrate of the article to which the agonist is applied. Does not correspond to the same substrate peak as previously observed; Identify the peak height of the primary agonist, which corresponds to the previously observed substrate peak, but which is the highest observation peak showing the greatest percentage increase in absorbance due to the presence of the conditioning agent. Record the wavelength number and absorbance of some effector peaks.

(4) From the spectrum determined in step 3, select a substrate peak that occurs at the wavelength number determined in step 2, but does not correspond to one of the primary agonist peaks selected in step 3. Record the number of selected wavelengths and the absorbance from the absorption spectrum of step 3.

(5) Calculate the ratio of the peak height of each agonist determined in step 3 to the peak height of the substrate determined in step 4. The highest number of groups represents the surface saturation ratio of the article.

Some examples include:

temperament* Substrate Peak and Peak Height conditioner for hair Conditioner peak height ratio Betting (a combination of thermally bonded polyester with 70% PET / PE dual component fibers) 0.0865 (C = O peak at 1710 cm ^-1 ) Glycerin (CO peak at 1030 cm ^-1 ) 0.181 2.09 Betting (a combination of thermally bonded polyester with 70% PET / PE dual component fibers) 0.0865 (C = O peak at 1710 cm ^-1 ) Hydrocarbons (CH peak at 2923 cm ^-1 ) 0.160 1.85 Weaving rayon 70% / 30% polyester 0.0333 (C = O peak at 1710 cm ^-1 ) Glycerin (CO peak at 1030 cm ^-1 ) 0.0684 2.05

* Substrates of this type are readily available, for example, from PGI Nonwovens (Benson, NC).

Moisture retention assay

As described above, the article of the present invention is considered " substantially dry. &Quot; As used herein, " substantially dry " means that the article of the present invention has less than about 0.95 gms, preferably less than about 0.75 gms, more preferably less than about 0.5 gms, even more preferably less than about 0.25 gms, Preferably less than about 0.15 gms, and most preferably less than about 0.1 gms. Moisture retention, as opposed to a " wet " feel of the wipe, Lt; / RTI >

In order to measure the moisture retention of the present article and other disposable substrate-based articles, the following equipment and materials are required.

Bounty White Paper Towel Procter & Gamble SKU 37000 63037 Base mass = 42.14 gms Scale Accuracy up to 0.0 g Lexan 0.5 "thick enough to cover the specimen completely, weighing 1000 g Weight 2000 g Weight or blend to 2000 g

Then, the two paper towels are weighted separately and each weight is recorded. Place one paper towel on a flat surface (for example, a laboratory bench). The sample article is placed on top of the towel. Place the other paper towel on top of the specimen item. The loxan is then placed and then placed on top of the specimen article weighing 2000 g. Wait one minute. After one minute, the weight and the laxan are removed. Weigh the upper and lower paper towels, and record the weight.

The moisture retention is calculated by subtracting the initial paper towel weight from the final weight (after one minute) for both the top and bottom paper towels. The weight differences obtained from the top and bottom paper towels are added. Assuming that multiple articles have been tested, the overall weight difference is averaged to obtain moisture retention.

Multi-Chambering Implementation Example

The article of the present invention may also include one or more chambers. The chamber or partition is created at the connection (e.g., bond) of the interstitial matrix layer to each other at various locations to define the enclosed site. The chamber is useful, for example, to separate surfactant-containing cleansing components from various article ingredients, e.g., conditioning agents, between each other. Detached article components that provide therapeutic or aesthetic or cleansing efficacy include, but are not limited to, solubilization, emulsification, mechanical delivery, pricking, detonating, exploding, ejecting, or even stripping the substrate layer that forms part of the chamber But may be released from the chamber in a variety of ways.

Optional ingredient

The articles of the present invention may include various other ingredients such as those commonly used in a given product type, so long as they do not unacceptably alter the efficacy of the present invention. The optional ingredients should be suitable for application to the human skin and hair, that is, when introduced into an article, it may be possible to use, without undue toxicity, incompatibility, instability, Suitable for use in contact with the skin. The CTFA Cosmetic Ingredient Handbook, Second Edition (1992), describes a wide variety of non-limiting cosmetic and pharmaceutical ingredients generally used in the skin care industry, suitable for use in the articles of the present invention. Examples of such constituent groups include: enzymes, abrasives, skin exfoliants, absorbents, aesthetic ingredients such as fragrances, pigments, dyeing / coloring agents, essential oils, skin senses, astringents etc. (for example, (For example, resorcinol, sulfur, salicylic acid, erythromycin, zinc, etc.), caking agents (such as, for example, coconut oil, camphor, eucalyptus oil, eugenol, menthyl lactate, witch hazel distillate) An antioxidant, a binder, a biological additive, a buffering agent, a bulking agent, a chelating agent, a chemical additive, a coloring agent, a cosmetic astringent, a cosmetic agent, an antiseptic, an antifoaming agent, an additive disinfectant (for example, iodopropyl butylcarbamate) A biocide, a biocide, a denaturant, a drug astringent, an analgesic for external use, a film former or substance, such as a polymer that assists film-forming properties and substantivity of the composition (e.g., a copolymer of icocene and vinylpyrrolidone (For example, hydroquinone, kojic acid, ascorbic acid, magnesium ascorbyl phosphate, ascorbyl glucosamine), skin, and the like may be added to the skin, (Eg, panthenol and derivatives (eg, ethyl panthenol), aloe vera, pantothenic acid and its derivatives, allantoin, bisabolol and dipotassium glycyrrhizinate), prevent, delay, (E.g., beta-hydroxy acids such as alpha-hydroxy acids and salicylic acid, such as lactic acid and glycolic acid), thickeners, hydrocolloids, particulate zeolites and vitamins And derivatives thereof (e.g., tocopherol, tocopherol acetate, beta carotene, retinoic acid, retinol, retinoid, retinyl palmitate, niacin, Amide, etc.). The article of the present invention may include a carrier component as is known in the art. The carrier may include one or more compatible liquid or solid fillers, diluents or carriers suitable for application to the skin or hair.

The article of the present invention may optionally include one or more of the optional components. Preferred articles include, but are not limited to, vitamin compounds, skin treatment agents, anti-wrinkle agents, anti-wrinkle agents, anti-skinning agents, antiinflammatory agents, topical anesthetics, artificial tanning agents and accelerators, antimicrobial agents, antifungal agents, sunscreen agents, A therapeutically effective amount of a therapeutically effective agent selected from the group consisting of: < RTI ID = 0.0 > As used herein, a " safe effective amount " means an amount that is sufficiently low to avoid significant side effects (e. G., Inappropriate toxicity or allergic response) sufficient to significantly induce a positive sexual effect or efficacy, , ≪ / RTI > the amount of a compound or ingredient that provides a reasonable efficacy-to-hazard ratio.

The optional ingredients useful herein can be categorized by their therapeutic or aesthetic efficacy or their assumed mode of action. However, it should be understood that the optional ingredients useful herein may provide, in some cases, more than one therapeutic or aesthetic efficacy, or may act through more than one mode of action. Therefore, the classification herein is for convenience and is not intended to limit the ingredients to the specific applications or applications listed. Also, where applicable, pharmaceutically acceptable salts of the components are useful herein.

Vitamin compound

The article of the present invention may include vitamin compounds, precursors, and derivatives thereof. The vitamin compounds may be in natural or synthetic form. Suitable vitamin compounds include, but are not limited to, vitamin A (e.g., beta carotene, retinoic acid, retinol, retinoid, retinyl palmitate, retinyl propionate etc.), vitamin B (such as niacin, niacinamide, riboflavin, pantothenic acid, ), Vitamin C (e.g., ascorbic acid, etc.), vitamin D (e.g. ergosterol, ergocalciferol, cholecalciferol, etc.), vitamin E (E. G., Phytonadione, menadione, phthiol, and the like) compounds.

In particular, the article of the invention may include a vitamin B ₃ compound in an effective amount of safety. Vitamin B ₃ compounds are described in co-pending U.S. Patent Application Serial No. 08 / 834,010, filed on April 4, 1997, International Publication WO 97/39733 A1 , ≪ / RTI > published), which is particularly useful for controlling skin conditions. The therapeutic ingredients of the present invention preferably contain from about 0.01% to about 50%, more preferably from about 0.1% to about 10%, even more preferably from about 0.5% to about 10% 1% to about 5%, and most preferably the vitamin B ₃ compound of from about 2% to about 5%.

As used herein, "vitamin B ₃ compound" means a compound having the formula; Derivatives thereof; ≪ / RTI > and any salt of said water:

Wherein R is -CONH ₂ (i.e., niacinamide), -COOH (i.e., nicotinic acid), or -CH ₂ OH (i.e., nicotinyl alcohol).

Typical derivatives of the above vitamin B ₃ compounds include nicotinic acid esters including non-vasodilating esters of nicotinic acid, nicotinyl amino acid, nicotinyl alcohol ester of carboxylic acid, nicotinic acid N-oxide and niacinamide N-oxide .

Examples of suitable vitamin B ₃ compounds are well known in the art and include many sources such as Sigma Chemical Company (St. Louis, Mo.); ICN Biomedicals, Inc. (Irvin, Calif.) And Aldrich Chemical Company (Milwaukee, Wis.).

Vitamin compounds can be included as substantially pure material or as extracts obtained by suitable physical and / or chemical isolation from natural (e.g., plant) sources.

Skin treatment agent

The article of the present invention may include one or more skin treatment agents. Suitable skin treatment agents include those effective in preventing, delaying, stopping / stopping or reversing skin wrinkles. Examples of suitable skin treatment agents include, but are not limited to, alpha-hydroxy acids such as lactic acid and glycolic acid and beta-hydroxy acids such as salicylic acid.

Acne Inhibitor

Examples of acne inhibitors useful in the articles of the present invention include keratolytic agents such as salicylic acid (o-hydroxybenzoic acid), salicylic acid derivatives such as 5-octanoylsalicylic acid and resorcinols; Retinoids such as retinoic acid and derivatives thereof (e.g., cis and trans); Sulfur-containing D and L amino acids and their derivatives and salts, especially the N-acetyl derivatives thereof, preferred examples of which are N-acetyl-L-cysteine; Lipoic acid; Benzoyl peroxide, octopirox, tetracycline, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 3,4,4'-trichlorobanilide, azelaic acid and its derivatives, phenoxy Antibiotics and antibacterial agents such as ethanol, phenoxypropanol, phenoxyisopropanol, ethyl acetate, clindamycin and mecocycline; Sebostat such as flavonoid; And bile salts such as scymnol sulfate and its derivatives, deoxycholate and cholate.

Anti-wrinkle agent and anti-skinning agent

Examples of wrinkle preventing agents and skin irritation preventing agents useful in the articles of the present invention include retinoic acid and derivatives thereof (e.g., cis and trans); Retinol; Retinyl ester; Niacinamide, salicylic acid and derivatives thereof; Sulfur-containing D and L amino acids and their derivatives and salts, especially N-acetyl derivatives, preferred examples of which are N-acetyl-L-cysteine; Thiols, such as ethanethiol; Hydroxysic acid, phytic acid, lipoic acid; Lysophosphatidic acid, and skin rinse agents (e.g., phenol and the like).

Non-steroidal anti-inflammatory drugs (NSAIDS)

Examples of NSAIDS useful in the articles of the present invention include the following categories: propionic acid derivatives; Acetic acid derivatives; Phenanic acid derivatives; Biphenylcarboxylic acid derivatives; And oxycam. All of these NSAIDS are fully described in U. S. Patent No. 4,985, 459 to Sunshine et al., Issued January 15,1995, the entire contents of which are incorporated herein by reference. Examples of useful NSAIDS include but are not limited to acetylsalicylic acid, ibuprofen, naproxen, beroxaprofen, flubiprofen, fenoprofen, penbufen, ketoprofen, indoprofen, Propanoprofen, myrroprofen, thioxaprofen, suroprofen, alminopropene, thiopropenoic acid, fluprofen and bacloxan. Also, steroid-based antiinflammatory drugs including hydrocortisone and the like are useful.

Local anesthetic

Examples of local anesthetics useful in the articles of the invention include, but are not limited to, benzocaine, lidocaine, bupivacaine, chlorprocaine, dibucaine, etidocaine, mephvacaine, tetracaine, diclonaine, hexylcaine, procaine, cocaine, Ketamine, pramoxine, phenol, and their pharmaceutically acceptable salts.

Artificial tanning and accelerating agents

Examples of artificial tanning agents and accelerators useful in the articles of the present invention include tyrosine esters such as dihydroxyacetone, tyrosine, ethyl tyrosinate and phospho-DOPA.

Antimicrobial and antifungal agents

Examples of antibacterial and antifungal agents useful in the articles of the invention include beta-lactam drugs, quinolone drugs, ciprofloxacin, norfloxacin, tetracycline, erythromycin, amikacin, 2,4,4'-trichloro-2'- Phenoxyethanol, phenoxypropanol, phenoxyisopropanol, doxycycline, capreomycin, chlorhexidine, chloretetracycline, oxytetracycline, clindamycin, ethambutol, But are not limited to, hexamidine isethionate, metronidazole, pentamidine, gentamicin, kanamycin, linemmaicin, methacycline, methenamine, minocycline, neomycin, netilmicin, paromomycin, streptomycin, tobramycin, Hydrochloride, erythromycin, zinc erythromycin, erythromycin esters, erythromycin But are not limited to, thiourea, tealea, amikacin sulfate, deoxycycline hydrochloride, capreomycin sulfate, chlorhexidine gluconate, chlorhexidine hydrochloride, chloretetracycline hydrochloride, oxytetracycline hydrochloride, clindamycin hydrochloride, ethambutol hydrochloride, But are not limited to, hydrochloric acid, hydrobromic acid, hydrochloric acid, hydrobromic acid, hydrochloric acid, hydrobromic acid, hydrochloric acid, hydrobromic acid, Pate, paromomycin sulfate, streptomycin sulfate, tobramycin sulfate, myconezole hydrochloride, amanpadine hydrochloride, amanpadine sulfide Etoposide, octopirox, parachlorometazolyl, nystatin, tolnaphthate, zinc pyrithione and clotrimazole.

Antiviral agent

The article of the present invention may further comprise one or more antiviral agents. Suitable antiviral agents include, but are not limited to, metal salts (e.g., silver nitrate, copper sulfate, iron chloride) and organic acids (e.g., malic acid, salicylic acid, succinic acid, benzoic acid, etc.). Certain compositions comprising an additional suitable antiviral agent include co-pending U. S. Patent Application Serial No. 09 / 421,084 (Beerse et al.), Filed October 19, 1999; 09 / 421,131 (Biedermann et al.); 09 / 420,646 (Morgan et al.); And 09 / 421,179 (Page et al.).

enzyme

The article of the present invention may optionally contain one or more enzymes. Preferably, the enzyme is dermatologically acceptable. Suitable enzymes include, but are not limited to, keratinase, protease, amylase, subtilisin, and the like.

Sunscreen

Sunscreens are also useful herein. A wide variety of sunscreen agents are disclosed in U. S. Patent No. 5,087, 445 to Haffey et al. On Feb. 11, 1992; U.S. Patent No. 5,073,372 issued to Turner et al. On Dec. 17, 1991; U.S. Patent No. 5,073,371 issued to Turner et al. On December 17, 1991; And Segarin et al., Chapter VIII of Cosmetics Science and Technology , p. 189 et seq.), All of which are incorporated herein by reference. Non-limiting examples of sunscreen agents useful in compositions of the present invention include 2-ethylhexyl p-methoxy cinnamate, 2-ethylhexyl N, N-dimethyl- Methoxy-t-butyldibenzoylmethane, 4-isopropyldibenzoylmethane, 3- (4-methoxyphenyl) benzoylmethane, 3- Benzylidene camphor, 3- (4-methylbenzylidene) camphor, titanium dioxide, zinc oxide, silica, iron oxide, and mixtures thereof. Other useful sunscreen agents include those disclosed in U.S. Pat. No. 4,937,370 (issued to Sabatelli on June 26, 1990) and U.S. Pat. No. 4,999,186 (issued to Sabatelli et al. On Mar. 3, 1991) Which is incorporated herein by reference. Particularly preferred examples of the sunscreen agent include 4-N, N- (2-ethylhexyl) methylaminobenzoate ester of 2,4-dihydroxybenzophenone, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester, 4- (2- 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester of dibenzoylmethane and dibenzoylmethane, and mixtures thereof. The exact amount of sunscreen agent that can be employed will depend on the sunscreen chosen and the sunscreen (SPF) to be achieved. SPF is commonly used to measure light protection of sunscreens for erythema. Which is incorporated herein by reference in its entirety. [ Federal Register , Vol. 43, No. 166, pp. 38206 - 38269 (Aug. 25, 1978).

Hydrocolloid

Hydrocolloids may also optionally be included in the article of the present invention. Hydrocolloids are well known in the art and aid in prolonging the useful life of the surfactants included in the cleansing component of the present invention so that the article can last for at least one full shower or bath. Suitable hydrocolloids include but are not limited to xanthan gum, carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, methyl and ethylcellulose, natural rubbers, gadrosugar rubbers, soybean rubbers, natural starches, deionized starches Octenyl succinate), and the like, but are not limited thereto.

Pyrogenic zeolite

Zeolites and other compounds that exothermically react when combined with water may also optionally be included in the article of the present invention.

Hydrogel-forming polymeric gelling agent

The article of the present invention may optionally include an aqueous gel formed from a hydrogel-forming polymeric gellant and water, i.e., a " hydrogel ". If an aqueous gel is present, the article preferably contains from about 0.1% to about 100%, more preferably from about 3% to about 50%, and most preferably from about 5% to about 50%, by weight of the water- 35% by weight of a hydrogel-forming polymeric gellant calculated on a dry weight basis of a hydrogel-forming polymeric gellant.

Generally, the hydrogel-forming polymeric gellant material of the present invention is an at least partially cross-linked polymer made from polymerizable unsaturated acid-containing monomers that become water soluble or hydrolytically soluble. This includes single ethylenically unsaturated compounds having at least one hydrophilic radical, including, but not limited to, olefinic unsaturated acids and anhydrides comprising at least one carbon-carbon olefinic double bond. With respect to the above monomers, water-soluble means that the monomer is soluble in deionized water at 25 DEG C at a level of 0.2% or more, preferably 1.0% or more.

Upon polymerization, the monomer units described above will generally contain from about 25 mole% to 99.99 mole%, more preferably from about 50 mole% to 99.99 mole%, most preferably from about 75 mole% to about 99.99 mole% of the polymeric gellant material (based on dry polymer weight) Mol% or more of an acid-containing monomer.

The hydrogel-forming polymeric gellants herein are partially crosslinked to a sufficient degree, preferably to such an extent that the resulting polymer does not exhibit a glass transition temperature (Tg) of less than about 140 占 폚, and thus the term " Hydrogel-forming polymeric gellant " shall mean a polymer that satisfies the above parameters. Preferably, the hydrogel-forming polymeric gellant has no Tg below about 180 DEG C, more preferably at about 370 DEG C or above, and does not have a Tg before decomposition of the polymer. The Tg can be measured by differential scanning calorimetry (DSC), which is carried out at a heating rate of 20.0 DEG C / min with a sample of 5 mg or less. Tg is calculated as the midpoint between the start point and the end point of the heat flow change corresponding to the glass transition on the DSC heat capacity heating curve. The use of DSC for Tg determination is well known in the art and is described in [B. Cassel and MP DiVito, " Use of DSC To Obtain Accurate Thermodynamic and Kinetic Data, " American Laboratory, 1994. 1., pp 14-19; Wunderlich, Thermal Analysis , Academic Press, Inc., 1990).

The hydrogel-forming polymeric material is characterized by being highly absorbent and capable of retaining water in its absorbed or " gel " state. The preferred hydrogel-forming polymeric gellants herein are capable of absorbing at least about 40 grams, preferably at least about 60 grams per gram, and more preferably at least about 80 grams per gram of gelling agent per gram of gelling agent (deionized water) will be. The value referred to herein as " absorbent capacity " can be determined according to the procedure of the " Tea Bag " absorption capacity test described above.

The hydrogel-forming polymeric gellants herein will generally be at least partially cross-linked. Suitable crosslinking agents are well known in the art and include, for example, (1) compounds having two or more polymerizable double bonds; (2) a compound having at least one functional group reactive with at least one polymerizable double bond and an acid-containing monomer material; (3) a compound having two or more functional groups reactive with an acid-containing monomer material; And (4) multivalent metal compounds capable of forming ionic crosslinks.

Crosslinking agents having two or more polymerizable double bonds include (i) di- or polyvinyl compounds such as divinylbenzene and divinyltoluene; (ii) a di- or polycarboxylic acid having an unsaturated mono- or polycarboxylic acid having a polyol, including, for example, di- or triacrylic esters of polyols, such as ethylene glycol, trimethylol propane, glycerine or polyoxyethylene glycol Polyester; (iii) bisacrylamides such as N, N-methylenebisacrylamide; (iv) carbamyl esters obtainable by reacting a polyisocyanate with a hydroxyl group-containing monomer; (v) di- or poly-allyl ethers of polyols; (vi) di- or poly-allyl esters of polycarboxylic acids such as diallyl phthalate, diallyl adipate and the like; (vii) esters of mono-allyl esters of polyols with unsaturated mono- or poly-carboxylic acids, such as acrylic acid esters of polyethylene glycol monoallyl ether; And (viii) di- or tri-allylamines.

Crosslinking agents having at least one functional group reactive with one or more polymerizable double bonds and acid containing monomeric materials include N-methylol acrylamide, glycidyl acrylate, and the like. Suitable cross-linking agents having two or more functional groups reactive with acid-containing monomeric materials include glyoxal; Polyols such as ethylene glycol and glycerol; Polyamines such as alkylenediamines (e.g., ethylenediamine), polyalkylene polyamines, polyepoxides, di- or polyglycidyl ethers, and the like. Suitable multivalent metal cross-linkers capable of forming ionic cross-linking include, for example, oxides, hydroxides and weak acids of alkaline earth metals (e.g., calcium, magnesium) and zinc, including calcium oxide and zinc diacetate Salts (e. G., Carbonates, acetates, etc.).

A number of crosslinking agents of this type are described in detail in U.S. Patent No. 4,076,663 to Masuda et al., Issued February 28, 1978, and U.S. Patent No. 4,861,539, issued to Allen et al. All of which are incorporated herein by reference. Preferred crosslinking agents include di- or polyesters of unsaturated mono- or polycarboxylic acid mono-allyl esters, bisacrylamides and di- or tri-allylamines of polyols. Specific examples of particularly preferable crosslinking agents include N, N'-methylenebisacrylamide and trimethylolpropane triacrylate.

The crosslinking agent will generally constitute from about 0.001 mole percent to about 5 mole percent of the resulting hydrogel-forming polymeric material. More generally, the cross-linking agent will comprise from about 0.01 mole percent to about 3 mole percent of the hydrogel-forming polymeric gellants used herein.

The hydrogel-forming polymeric gellants herein may be employed in their partially neutralized form. For purposes of the present invention, the material is considered partially neutralized when at least 25 mole%, preferably at least 50 mole% of the monomers used to form the polymer are acid group-containing monomers neutralized with a base . Suitable neutralizing base cations include, but are not limited to, hydroxides of alkaline and alkaline earth metals (e.g., KOH, NaOH), ammonium, substituted ammonium and amino alcohols (e.g., Diethanolamine and 2-amino-2-methyl-1-propanol). The percentage of total monomer used, which is a neutralized acid group-containing monomer, is referred to herein as " neutralization degree ". The degree of neutralization will preferably not exceed 98%.

Hydrogel-forming polymeric gelling agents suitable for use herein are well known in the art and include, for example, U.S. Pat. No. 4,076,663 issued to Masuda et al. On Feb. 28, 1978; U.S. Pat. No. 4,062,817 issued to Westerman on December 13, 1977; U.S. Patent No. 4,286,082 issued to Tsubakimoto et al. On Aug. 25, 1981; U.S. Patent No. 5,061,259 (issued to Goldman et al. On Sep. 29, 1991), and U.S. Patent No. 4,654,039 (issued to Brandt et al., Issued March 31, 1987), each of which is incorporated herein by reference Quoted.

Suitable hydrogel-forming polymeric gellants for use herein are also disclosed in U.S. Patent No. 4,731,067 (issued to Le-Khac on May 3, 1988), U.S. Patent No. 4,743,244 (issued to Le- U. S. Patent No. 4,813,945 issued to Le-Khac on March 21, 1989, U.S. Patent No. 4,880,868 issued to Le-Khac on Apr. 14, 1989, U.S. Patent No. 4,892,553 issued to Le- U. S. Pat. No. 5,026,784 issued to Le-Khac on June 25, 1991, US 5,079,306 issued to Le-Khac on January 7, 1992, U.S. Patent No. 4,861,539 (granted to Allen, Farrer and Flesher on Aug. 29, 1989) and U.S. Patent No. 4,962,172 (Allen, Farrer and Flesher, 1990) to U.S. Patent No. 5,151,465 And 10.9, respectively, each of which is incorporated herein by reference.

Suitable hydrogel-forming polymeric gellants in particulate form are available from Hoechst Celanese Corporation (Portsmouth, VA, USA) (Sanwet ^TM superabsorbent polymer), Nippon Shokubai, Japan (Aqualic ^TM , And Dow Chemical Company (Midland, MI, USA) (Dry Tech ^TM ).

The hydrogel-forming polymeric gelling agent in fiber form is available from Camelot Technologies Inc. (Leominster, MA, USA) (Fibersorb ^TM , for example SA 7200H, SA 7200M, SA 7000L, SA 7000 and SA 7300).

The article of the present invention may also include other hydrophilic gelling agents. Such water includes carboxylic acid containing polymers as described above, but also cellulose ethers (e.g., hydroxyethylcellulose, methylcellulose, hydroxypropylmethylcellulose, hydroxypropylmethylcellulose, hydroxypropylmethylcellulose, Methylcellulose), polyvinylpyrrolidone, polyvinyl alcohol, guar gum, hydroxypropyl guar gum, and xanthan gum. Other water-soluble or colloidal water-soluble polymers are also included. Of these additional hydrophilic gelling agents, acid-containing polymers, especially carboxylic acid-containing polymers, are preferred. In particular, those comprising a water-soluble polymer of acrylic acid crosslinked with a polyalkenyl polyether of a polyhydric alcohol and, optionally, an acrylate ester or a polyfunctional vinylidene monomer are preferred.

Preferred copolymers useful in the present invention include from 95 to 99% by weight of an olefinically unsaturated carboxyl monomer selected from the group consisting of acrylic acid, methacrylic acid and ethacrylic acid; About 1 to about 3.5 weight percent acrylate ester of the formula:

Wherein R is an alkyl radical of 10 to 30 carbon atoms and R < ₁ > is hydrogen, methyl or ethyl; And a polyhydric alcohol containing at least one alkenyl ether group per molecule wherein the parent polyhydric alcohol contains at least three carbon atoms and at least three hydroxyl groups. Crosslinkable polyalkenyl polyether 0.1 to 0.6 % ≪ / RTI > by weight of a monomer mixture.

Preferably, the polymer comprises about 96 to 97.9% by weight of acrylic acid and about 2.5 to about 3.5% by weight of acrylic ester, wherein the alkyl groups have from 12 to 22 carbon atoms, R ₁ is methyl, Is acrylate ester is stearyl methacrylate). Preferably, the amount of cross-linked polyalkenyl polyether monomer is from about 0.2 to 0.4 wt%. Preferred crosslinked polyalkenyl polyether monomers include allylpentaerythritol, trimethylolpropane diallyl ether, or allyl sucrose. Such polymers are described in detail in U.S. Patent No. 4,509,949 (Huang et al., Issued April 5, 1985), which is incorporated herein by reference in its entirety.

Other preferred copolymers useful in the present invention are polymers comprising two or more monomeric components, one of which is a monomeric olefinically unsaturated carboxylic acid and the other is a polyether, polyalkenyl, polyalcohol. If desired, additional monomeric materials may be present in the monomeric mixture in predominant proportions.

The first monomeric component useful in the preparation of said carboxyl polymer is an olefinically unsaturated carboxylic acid comprising at least one activated carbon-carbon olefinic double bond, and at least one carboxyl group. Preferred carboxylic acid monomers are acrylic acid having the formula:

Wherein R ² is a substituent selected from the group consisting of hydrogen, halogen, and a cyanogen (C = N) group, a monovalent alkyl radical, a monovalent alkaryl radical, and a monovalent cycloaliphatic radical. Of these groups, acrylic acid, methacrylic acid and ethacrylic acid are most preferred. Other useful carboxyl monomers include maleic anhydride or maleic acid. The amount of acid used will be from about 95.5 to about 98.9 wt%.

The second monomeric component useful for the preparation of such a carboxyl-based polymer includes polyolefins having more than one alkenyl ether group per molecule, such as an alkenyl group in which the olefinic double bond is attached to the terminal methylene group CH ₂ = C < There are alkenyl polyethers.

In additional monomeric materials which may be present in the polymer, for example, butadiene, isoprene, divinyl benzene, divinyl naphthyl teulren, allyl acrylate, and the like, at least two terminal CH ₂ <polyfunctional vinyl group-containing, including Lidene monomers. These polymers are described in detail in U.S. Patent No. 2,798,053 (granted to Brown, July 2,1957), which is incorporated herein by reference in its entirety.

Examples of carboxylic acid copolymers useful in the present invention include Carbomer 934, Carbomer 941, Carbomer 950, Carbomer 951, Carbomer 954, Carbomer 980, Carbomer 981, Carbomer 1342, Acrylate / C10-30 alkyl acrylate crosspolymers Carbopol 934, Carbopol 950, Carbopol 951, Carbopol 954, Carbopol 980, Carbopol 981, Carbopol 1342, and Pemulen series from Goodrich).

Other carboxylic acid copolymers useful in the present invention include sodium salts of acrylic acid / acrylamide copolymers sold under the tradename Hostaceren PN73 by Hoechst Celanese Corporation. Further, Lipo Chemicals Inc. Also include hydrogel polymers sold under the trade name HYPAN hydrogel. The hydrogel consists of crystalline plicks of C-C backboned nitrate with various other protons such as carboxyl, amide, and amidine. Examples include HYPAN SA 100 H, a polymer powder available from Lipo Chemical.

The neutralizing agents used to neutralize the acid groups of the polymer include those described above.

Cationic surfactant

Cationic surfactants are typically classified as non-foam forming surfactants, but may be used in the articles of the present invention, unless they have a negative effect on the desired efficacy of the article.

Non-limiting examples of cationic surfactants useful herein are described in McCutcheon ' s Detergents and Emulsifiers , North American edition (1986), published by allured Publishing Corporation; And McCutcheon ' s, Functional Materials , North American Edition (1992); Both of which are incorporated herein by reference.

Non-limiting examples of cationic surfactants useful herein include cationic alkylammonium salts such as those having the formula:

R ₁ R ₂ R ₃ R ₄ N ⁺ X ^-

(Wherein, R ₁ has from about 12 to about 18 alkyl carbon atoms, or from about 12 to about 18 carbon atoms, aromatic, is selected from an aryl or alkaryl group; R _2, R ₃ and R ₄ is hydrogen, from about 1 to Aryl, or alkaryl group of from about 12 to about 18 carbon atoms; X is selected from the group consisting of chloride, bromide, iodide, acetate, phosphate, nitrate, sulfate, Is an anion selected from the group consisting of phosphate, ethyl sulfate, tosylate, lactate, citrate, glycolate, and mixtures thereof. Additionally, the alkyl group may also include an ether bond, or a hydroxy or amino group substituent (e.g., the alkyl group may include polyethylene glycol and polypropylene glycol moieties).

More preferably, R &lt; ₁ &gt; is an alkyl group of about 12 to about 18 carbon atoms; R ₂ is selected from H or an alkyl group of from about 1 to about 18 carbon atoms; R ₃ and R ₄ are independently selected from H or an alkyl group of from about 1 to about 3 carbon atoms; X is as described in the above paragraph.

Most preferably, R &lt; ₁ &gt; is an alkyl group of about 12 to about 18 carbon atoms; R ₂ , R _3, and R ₄ are selected from H or an alkyl group of from about 1 to about 3 carbons; X is as described above.

Alternatively, other useful cationic surfactants include amino-amides, wherein R ₁ is optionally R ₅ CO- (CH ₂ ) _n -, wherein R ₅ is from about 12 to about 22 And n is an integer from about 2 to about 6, more preferably from about 2 to about 4, and most preferably from about 2 to about 3). Non-limiting examples of the cationic emulsifier include stearamidopropyl PG-dimonium chloride phosphate, stearamidopropyl ethyl dimonium ethosulfate, stearamidopropyl dimethyl (myristyl acetate) ammonium chloride, stearamidopropyl dimethyl Cetearyl ammonium tosylate, stearamidopropyl dimethyl ammonium chloride, stearamidopropyl dimethyl ammonium lactate, and mixtures thereof.

Nonlimiting examples of quaternary ammonium salt cationic surfactants include cetyl ammonium chloride, cetyl ammonium bromide, lauryl ammonium chloride, lauryl ammonium bromide, stearyl ammonium chloride, stearyl ammonium bromide, cetyldimethyl ammonium chloride, cetyldimethyl ammonium bromide , Lauryl dimethyl ammonium chloride, lauryl dimethyl ammonium bromide, stearyl dimethyl ammonium chloride, stearyl dimethyl ammonium bromide, cetyl trimethyl ammonium chloride, cetyl trimethyl ammonium bromide, lauryl trimethyl ammonium chloride, lauryl trimethyl ammonium bromide, Ammonium chloride, stearyltrimethylammonium bromide, lauryldimethylammonium chloride, stearyldimethylcetyldialdimethylammonium chloride Dicetylammonium chloride, dicetylammonium bromide, dicetylammonium bromide, distearylammonium bromide, distearylammonium chloride, distearylammonium bromide, dicetylmethylammonium chloride, dicetylmethylammonium bromide, dilaurylmethylammonium bromide, But are not limited to, those selected from the group consisting of chloride, dilaurylmethylammonium bromide, distearylmethylammonium chloride, distearyldimethylammonium chloride, distearylmethylammonium bromide, and mixtures thereof. Additional quaternary ammonium salts include those in which the C12 to C22 alkyl carbon chain is derived from tallow fatty acids or coconut fatty acids. The term " tallow " refers generally to an alkyl group derived from a tallow fatty acid (usually a hydrogenated tallow fatty acid) having a mixture of alkyl chains in the C16 to C18 range. The term " coconut " refers generally to alkyl groups derived from coconut fatty acids having a mixture of alkyl chains in the C12 to C14 range. Examples of quaternary ammonium salts derived from the tallow and coconut sources include ditallow dimethyl ammonium chloride, ditallow dimethyl ammonium methyl sulfate, di (hydrogenated tallow) dimethyl ammonium chloride, di (hydrogenated tallow) dimethyl ammonium acetate, Di (coconut alkyl) dimethyl ammonium chloride, di (coconut alkyl) dimethyl ammonium bromide, tallow ammonium chloride, coconut ammonium chloride, stearamidopropyl PG-dimonium chloride phosphate , Stearamidopropyl ethyl dimonium ethosulfate, stearamidopropyl dimethyl (myristyl acetate) ammonium chloride, stearamidopropyl dimethyl cetearyl ammonium tosylate, stearamidopropyl dimethyl ammonium chloride , Stearic amino also includes the profile dimethyl ammonium lactate, and mixtures thereof.

Preferred cationic surfactants useful herein include the group consisting of dilauryldimethylammonium chloride, distearyldimethylammonium chloride, dimyristyldimethylammonium chloride, dipalmityldimethylammonium chloride, distearyldimethylammonium chloride, and mixtures thereof &Lt; / RTI &gt;

Chelators

The article of the present invention may also include a safe effective amount of a chelator or chelating agent. As used herein, " chelator " or " chelating agent " refers to an activator capable of removing metal ions from the system by forming a complex so that the metal ion does not readily react or catalyze a chemical reaction. The introduction of chelating agents is particularly useful in providing protection against UV radiation that can contribute to excessive scaling or skin texture changes, and other environmental factors that can cause skin damage.

A safe effective amount of a chelating agent may be added to the compositions of the present invention, preferably from about 0.1% to about 10%, more preferably from about 1% to about 5% of the composition. Examples of chelators useful herein are described in U.S. Patent No. 5,487,884 (issued to Bissett et al. On Jan. 1, 1996); International Publication No. 91/16035 (published on October 31, 1995 by Bush et al.); And International Publication No. 91/16034 (published on October 31, 1995 to Bush et al.). Preferred chelators useful in the compositions of the present invention include furidie oxime and derivatives thereof.

Flavonoid

The article of the present invention may optionally contain a flavonoid compound. Flavonoids are broadly disclosed in U.S. Patent Nos. 5,686,082 and 5,686,367, both of which are incorporated herein by reference. Flavonoids suitable for use in the present invention include flavanone selected from the group consisting of unsubstituted flavanone, mono-substituted flavanone, and mixtures thereof; A chalcone selected from the group consisting of unsubstituted chalcone, monosubstituted chalcone, disubstituted chalcone, trisubstituted chalcone, and mixtures thereof; Flavone selected from the group consisting of unsubstituted flavones, monosubstituted flavones, disubstituted flavones, and mixtures thereof; One or more isoflavones; Coumarin selected from unsubstituted coumarin, monosubstituted coumarin, disubstituted coumarin, and mixtures thereof; A chromium selected from the group consisting of unsubstituted chromone, monosubstituted chromone, diisocyanate chromone, and mixtures thereof; One or more decumaroles; One or more chromanones; One or more chromanol; Isomers thereof (e.g., cis / trans isomers); And mixtures thereof. The term " substituted " as used herein means a flavonoid in which one or more hydrogen atoms of the flavonoid are independently replaced by hydroxyl, C 1 -C 8 alkyl, C 1 -C 4 alkoxyl, O-glycoside, do.

Examples of suitable flavonoids include, but are not limited to, unsubstituted flavanone, mono-hydroxy flavanone (such as 2'-hydroxy flavanone, 6-hydroxy flavanone, Methoxy flavanone, 7-methoxy flavanone, 4'-methoxy flavanone, etc.), unsubstituted chalcone (especially unsubstituted tras-chalcone), mono -Hydroxychalcone (e.g., 2 ', 4-dihydroxychalcone, 2', 4 '-hydroxychalcone and the like) Dihydroxycalcone, 2,2'-dihydroxycalcone, 2 ', 3-dihydroxychalcone, 2', 5'-dihydroxychalcone), and trihydroxychalcone (for example, 2 3 ', 4'-trihydroxychalcone, 4,2', 4'-trihydroxychalcone and 2,2 ', 4'-trihydroxychalcone), unsubstituted flavone, 7,2'- Dihydroxyflavone, 3 ', 4'-dihydroxynaphtho toflavone, 4'-hydroxyflavone, 5,6-benzofurine And 7,8-benzoflavone, unsubstituted isoflavone, daidzein (7,4'-dihydroxyisoflavone), 5,7-dihydroxy-4'-methoxyisoflavone, soy isoflavone (Mixture extracted from soybeans), unsubstituted coumarin, 4-hydroxycoumarin, 7-hydroxycoumarin, 6-hydroxy-4-methyl coumarin, 6-isopropylchromone, unsubstituted dicumarol, unsubstituted chromanone, unsubstituted chromanol, and mixtures thereof.

Unsubstituted flavanone, methoxy flavanone, unsubstituted chalcone, 2 ', 4-dihydroxychalcone, and mixtures thereof are preferred for use herein. Unsubstituted flavanone, unsubstituted chalcone (especially trans isomers), and mixtures thereof are most preferred.

They can be synthetic or obtained as extracts from natural sources (e.g., plants). Natural source materials may be further derivatized (e. G. Glycosides, esters or ether derivatives prepared after extraction from natural sources). Flavonoid compounds useful herein may be obtained from a number of sources, such as the Indofine Chemical Company, Inc. (Somerville, New Jersey), Steraloids, Inc. (Wilton, New Hampshire), and Aldrich Chemical Company, Inc. (Milwaukee, Wis.).

Mixtures of the above flavonoid compounds may also be used.

The flavonoid compounds described herein are preferably present in the present invention at a concentration of from about 0.01% to about 20%, more preferably from about 0.1% to about 10%, and most preferably from about 0.5% to about 5%.

Sterol

The article of the present invention may include a safe effective amount of one or more sterol compounds. Examples of useful sterol compounds include sitosterol, stigmasterol, campesterol, brassicasterol, lanosterol, 7-dihydrocholesterol, and mixtures thereof. These may be synthetic or natural sources, for example, a blend extracted from a plant source (e.g., phytosterol).

Anticellulite

The article of the invention may also contain a safe effective amount of an anti-cellulite agent. Suitable materials include, but are not limited to, xanthine compounds (e. G., Caffeine, theophylline, theobromine, and aminophylline).

Skin whitening agent

The article of the present invention may contain a skin lightening agent. When used, the composition preferably comprises from about 0.1% to about 10%, more preferably from about 0.2% to about 5%, and more preferably from about 0.5% to about 2% Bleaching agents are included. Suitable skin lightening agents include those known in the art, including kojic acid, arbutin, ascorbic acid and derivatives thereof, such as magnesium ascorbyl phosphate or other salts of sodium ascorbyl phosphate or ascorbyl phosphate do. Suitable skin lightening agents for use herein also include co-pending patent application Serial No. 08 / 479,935 (filed on June 6, 1995, Hillebrand, corresponding PCT application US 95/07432 )); And co-pending patent application Ser. No. 08 / 390,152 (Kalla L. Kvalnes, Mitchell A. DeLong, Barton J. Bradbury, Curtis B. Motley and John D. Carter, Including those described in US 95/02809 (filed April 1, 1995, September 9, 1995).

Binder

The article of the present invention may optionally contain a binder. Binders or binding materials are useful for maintaining the integrity of an article by sealing multiple layers of the article of the present invention together. The binder may be in a variety of forms including, but not limited to, spray, net, individual layers, bonded fibers, and the like. Suitable binders may include latexes, polyamides, polyesters, polyolefins, and combinations thereof.

Additional layer

In another embodiment, the article of the present invention may include one or more additional layers, which are recognized by those skilled in the art as being separate and distinct from the first and second layers, but which are attached to the two layers at the same point. The additional layer is suitable for enhancing the overall grippability of the article surface closest to the hand or other means to impart a mechanical action on the surface to be cleansed. In addition, the additional layer is suitable for enhancing the soft feel of the surface of the article in contact with the area to be cleansed and / or treated therewith. In all cases, the additional layer may also be referred to as a continuous layer, for example a third layer, a fourth layer, etc., in addition to the two essential layers of the article of the present invention.

Suitable additional layers can be macroscopically expanded. As used herein, the term " macroscopically expanded " means that when the vertical distance between the observer's eye and the plane of the screen is about 12 inches, the surface deformations involving the pattern are normal visual (i.e. normal visual with 20/20 visual acuity) Ribbons, and films that are individually distinguishable on a three-dimensional forming structure so that both surfaces exhibit a three-dimensional forming pattern of surface deformation corresponding to the macroscopic cross-section of the forming structure.

As used herein, " embossed " means that the molding structure of a material refers to a pattern consisting primarily of male-projections. On the other hand, " debossed " means that the molding structure of the material represents a pattern consisting primarily of a depressed capillary network.

A preferred macroscopically expanded film includes a shaped film that is a structural resiliently similar film. Such films are described in U.S. Patent No. 5,554,145 (Roe et al., Issued October 9, 1996), the entire contents of which are incorporated herein by reference.

Suitable materials for use in additional layers having a thickness of at least one millimeter include, but are not limited to, those disclosed in U.S. Patent No. 5,518,801 (to Chappell et al., Issued May 5, 1996) Which is incorporated herein by reference.

Manufacturing method

The personal care articles of the present invention may include, but are not limited to, sprinkling, dip coating, spraying, slot coating, and roll delivery (e. G., Pressure rolls or kiss rolls) By adding a cleansing component and / or a therapeutic efficacy component to the appropriate sheet of the first or second layer. The sheet of the remaining layer is then placed on the sheet of the first layer, preferably over the cleansing component and / or the therapeutic effect ingredient, but this is not always the case. The sheets may be sealed together by conventional sealing methods, including, but not limited to, heating, pressure, adhesive, ultrasound, and the like. Thermal sealing devices can be of various designs and can be made of a low melt (e.g., polyether) fiber such as a polyamide fiber mesh known as Wonder Under (available from Pellon and marketed by H. Levinson & Co., Chicago, IL) The intercalation layer of the heat-shrink synthetic fiber web can be used between the layers of the above and other embodiments without changing the effectiveness or use of the article. Subsequently, the sealed sheet is divided into units suitable for the consumer's use. Optional manufacturing steps may include calendaring, drying, creping, shrinking, stretching, or other mechanical deformation to level the article.

Cleansing to skin or hair and delivery of therapeutic or cosmetic agonists

The present invention also relates to a method of cleansing the skin or hair with the personal care article of the present invention. Said method comprising the steps of: a) providing a substantially dry, disposable personal care article suitable for cleansing, said soft first layer exhibiting a total scratch cover value of less than about 17% Wherein the second layer exhibits a total scratch cover value of from about 17% to about 70%, and a cleansing component in the vicinity of the first and second layers Comprises a foam-forming surfactant that is from about 10% to about 1000% by weight of the water-insoluble substrate), and b) contacting the wetted article with the skin or hair. Additionally, the present invention relates to a skin and hair cleansing method comprising the following steps: a) a substantially dry, disposable personal care article suitable for cleansing, said article having an average profile of less than about 8 meter depth value A water-insoluble substrate comprising a soft first layer representing the first layer and a second layer for peeling located adjacent to the first layer, the second layer representing a meter depth value from an average profile of from about 8 to about 80; Wetting a cleansing component in the vicinity of the first and second layers, wherein the component comprises from about 10% to about 1000% by weight of the water-insoluble substrate of a foam-forming surfactant; And b) bringing the wetted article into contact with the skin or hair.

Additional methods include similar steps using articles exhibiting the residual physical properties disclosed herein.

In another embodiment, the invention is useful for delivering a therapeutic efficacy component to a site in need of treatment (e.g., skin, hair, etc.), wherein the method comprises the following additional steps: A substantially dry disposable personal care article as described in the preceding paragraph; And 2) wetting with water a therapeutically efficacious component that is placed near the water-insoluble substrate, wherein the component comprises about 10% to about 1000% by weight of the therapeutic agent, of the water-insoluble substrate; And B) bringing the skin or hair into contact with the wetted article.

The article of the present invention is water-activated and therefore must be wetted with water before use. As used herein, "water-activated" means that the present invention is provided to the consumer in a dry form which must be used after wetting with water. When the article of the present invention contains a foam-forming surfactant, they are found to be bubbled or " activated " after contact with water and subsequent stirring. Thus, the article is wetted by immersion in water or by placing it under a stream of water. When the article of the present invention includes a foam-forming surfactant in the cleansing composition, it may be possible to create foam from the article by mechanically agitating and / or deforming the article before or during contact with the skin or hair. The resulting foam is useful for cleansing the skin or hair. During the cleansing process and subsequent rinsing with water, any therapeutic or aesthetic agent is deposited on the skin or hair. The deposition of therapeutic or aesthetic agonists is enhanced not only by the physical contact of the substrate with the skin or hair, but also by the introduction of one or more deposition aids.

The present invention relates to disposable personal care articles useful for the therapeutic treatment and cleansing of skin, hair and any other location where treatment is required. Wherein the article has a soft first layer exhibiting a total scratch coverage value of less than about 17% and a second peelable layer adjacent to the first layer, wherein the second layer comprises about 17% to about 70% % &Lt; / RTI &gt; total scratch cover value); And from about 10% to about 1000% by weight of the water-insoluble substrate comprises from about 10% to about 1000% by weight of a cleansing component or water-insoluble substrate comprising a foam-forming surfactant, Or both. The article also includes a soft first layer exhibiting an Average Profilometer Depth Value of less than about 8 with an average profile and a second layer lying about the first layer, A mean profile representing the meter depth value); And from about 10% to about 1000% by weight of the water-insoluble substrate, of a cleansing component comprising a foam-forming surfactant that is from about 10% to about 1000% by weight of the water-insoluble substrate Or both. The consumer rubs the article with water and rubs them at the site to be cleansed and / or treated (e. G., Conditioned).

The present invention also includes a method of cleansing and / or conditioning skin and hair using the article of the present invention.

The following examples further illustrate and demonstrate embodiments within the scope of the present invention. In the following examples, all components are listed at the active level. The embodiments are provided for illustrative purposes only, and many variations thereof are possible without departing from the spirit and scope of the invention, and should not be construed as limiting the invention.

Components are identified by chemical name or CTFA name.

Ⅰ. Cleansing ingredient

Example 1

Representative cleansing ingredients for the articles of the present invention are prepared in the following manner.

Slice the bar soap 53.0 gms containing the following ingredients:

ingredient weight% Sodium cochleate isethionate 27.77 paraffin 16.72 Sodium alkyl glycerol sulfonate (AGS) 14.90 soap 11.41 glycerin 8.57 water 5.50 Stearic acid 5.74 Sodium isethionate 3.04 NaCl 1.41 EDTA 0.10 Etidronate 0.10 Polyox 0.03 Spices 0.70 Other (with pigment) 4.01 synthesis 100

The bar soap scum is mixed with 37.0 gms of glycerin (99.7%), 9.5 gms of water and 0.5 gms of perfume. The mixture is heated to 200 DEG F while stirring continuously. The mixture is cold-milled in a standard three-roll grinder and the cleansing ingredients are stored in a suitable sealed container.

Example 2

Representative cleansing ingredients for the articles of the present invention are prepared in the following manner.

Slice 40.0 gms of bar soap containing the following ingredients:

ingredient weight% Sodium soap 52.40 Sodium alkyl glycerol sulfonate (AGS) 16.50 Magnesium soap 13.40 glycerin 0.19 water 5.50 Stearic acid 1.60 Sodium isethionate 3.00 NaCl 3.89 EDTA 0.10 Etidronate 0.10 Spices 0.70 Other (with pigment) 2.62 synthesis 100

The bar soap scum is mixed with 45.0 gms of glycerin (99.7%), 4.5 gms of water and 0.5 gms of perfume. The mixture is heated to 200 DEG F while stirring continuously. The mixture is cold-milled in a standard three-roll grinder and the cleansing ingredients are stored in a suitable sealed container.

Example 3

Representative powder cleansing ingredients for the articles of the present invention are prepared in the following manner.

Slice 40.0 gms of bar soap containing the following ingredients:

ingredient weight% Soap (magnesium and sodium) 80.16 water 11.50 Stearic acid 5.70 NaCl 1.10 EDTA 0.25 Spices 1.15 Other (with pigment) 0.14 synthesis 100

Store the bar soap flakes in a properly sealed container.

Example 4

Representative powder cleansing ingredients for the articles of the present invention are prepared in the following manner.

Slice 40.0 gms of bar soap containing the following ingredients:

ingredient weight% Soap (magnesium and sodium) 80.16 water 11.50 Stearic acid 5.70 NaCl 1.10 EDTA 0.25 Spices 1.15 Other (with pigment) 0.14 synthesis 100

The rod soap flakes are combined with sodium bicarbonate in a weight ratio of 90:10. The mixture is pulverized twice in a standard 3-roll mill. The flakes are collected and stored in a suitably sealed container.

Example 5

Representative cleansing ingredients for the articles of the present invention are prepared in the following manner. The cleansing component of Example 2 is combined with 0.1% by weight of the bar soap flakes of the protease enzyme. The resulting mixture is then blended with sodium carboxymethylcellulose, a dry hydrocolloid which is 2% by weight of the cleansing component, and ground. Store enzyme cleansing ingredients in appropriate sealed containers.

Example 6

A representative liquid cleansing component comprising the following ingredients is prepared.

ingredient weight% Sodium coconut alkyl glyceryl sulphonate (AGS) 7.2 Ammonium lauryl sulfate (ALS) 10.4 Alkyl laureth sulfate (AE3S) 10.4 Poly (ethylene oxide) (PolyOx WSR N-3000, Union Carbide) 0.5 Xanthan gum 1.4 water 70.1

Example 7

Representative cleansing ingredients for the articles of the present invention are prepared in the following manner. Heat 3 lbs of the soap debris of Example 2 with 3/4 cup isopropyl alcohol (99%) until the soap melts. When the soap has melted, add the remaining alcohol. As little as possible, a table sugar 10 oz. Lt; / RTI &gt; Dye about 4 tsp. Glycerin 8 oz. . Glycerin (99.7%) is added. Lt; / RTI &gt; Continue heating until the aliquot of material is cured as the viscosity changes with a ribbon-like ribbon in a dilute liquid as the stirrer is removed and dropped onto a cool surface. The mixture is poured into an appropriate container and cured. The mixture has the advantage of re-melting during the heating process which facilitates the process for producing the article.

Example 8

A typical eye-free liquid cleansing composition comprising the following ingredients is prepared.

ingredient weight% Cocamidopropyl betaine 17.1 Sodium trideceth sulfate 8.3 POE 100 sorbitan monooleate 7.5 Others (including fragrances, preservatives, dyes) 2.0 water 65.1

A distinctive feature of the composition is its non-irritating properties to the skin and eyes.

Example 9

A representative liquid cleansing component comprising the following ingredients is prepared.

ingredient weight% Polyquaternium 10 0.50 Sodium lauroamphoacetate 5.4 Sodium laureate 3 sulfate 11.6 Disodium EDTA 0.20 Sodium citrate dihydrate 0.50 Anhydrous citric acid 1.0 PEG-6 caprylic / capric acid glyceride 2.0 Cocamide MEA 2.0 glycerin 3.5 MgSO ₄ -7H ₂ O (epsom salt) 1.5 Maleate soybean oil 2.5 Deodorizing soybean oil 5.0 Others (including fragrances, caustics, and colorants) 1.5 water 62.8

The mixture is gentle for use on sensitive skin.

Example 10

A representative liquid cleansing component comprising the following ingredients is prepared.

ingredient weight% Polyquaternium-10 0.1 Sodium sulfate 1.5 Lauryl alcohol 0.3 Sodium laureth sulfate 5.8 Anhydrous citric acid 0.2 Cocamidopropyl betaine 15.5 Sodium lauroyl sarcosinate 1.5 Others (including fragrance, blue colorant) 1.0 water 74.1

Example 11

A representative cleansing component comprising the following ingredients is prepared.

ingredient weight% Decyl polyglucose 12.0 Cocamidopropyl betaine 12.0 Sodium lauroyl sarcosinate 12.0 Butylene glycol 3.6 PEG 14M 1.8 Polyquaternium-10 0.9 Dexpanthenol 0.7 Phenoxyethanol 0.5 Benzyl alcohol 0.5 Methyl paraben 0.45 Propylparaben 0.25 Disodium EDTA 0.2 water 55.1

Example 12

A representative cleansing component comprising the following ingredients is prepared.

ingredient weight% EGDS 3.1 Cocamidopropyl betaine 4.0 TEA soap (molecular weight about 330) 9.5 Monoalkyl phosphate 15.0 Cocamine oxide 7.5 1,2-propanediol 1.0 ethanol 3.0 Others (fragrance, colorant, preservative) 8.9 water 48.0

The mixture is heated to 5O &lt; 0 &gt; C with continued stirring until the mixture loses 38% of its original weight and has a paste-like viscosity. The cleansing component is advantageously easy to process with the substrate layer and does not require further drying.

Example 13

A representative cleansing component comprising the following ingredients is prepared.

ingredient weight% SEFA ^* Cotonate 57.5 Citric acid 0.30 Cocamidopropyl betaine 3.5 Sodium lauroyl sarcosinate 10.7 Ethylene vinyl acetate polymer (Elvax 40W) 8.0 Silicone polymer microbeads (Tospearly 145A) 20.0

^* SEFA is an acronym for sucrose esters of fatty acids.

The ethylene vinyl acetate polymer is melted at 90 DEG C with SEFA cotonate and high shear mixed. Add surfactant powder and citric acid and mix. Silicone polymer microbeads are added, mixed and allowed to cool. The composition is re-meltable and is easily impregnated or coated on the fabric.

Example 14

A representative cleansing component comprising the following ingredients is prepared.

ingredient weight% Sodium laureth-10 carboxylate (Empicol CB5S ^* ) 50.0 C12-14, 12EO alcohol ethoxylate (Empilan KB12 ^* ), 50.0

^* Available from Albright & Wilson

The alcohol ethoxylate is melted, blended in the carboxylate until homogeneous and cooled and solidified until ready for use. The composition is re-meltable and is easily impregnated or coated on the fabric.

Example 15

A representative cleansing component comprising the following ingredients is prepared.

ingredient weight% Monosodium lauroyl glutamate 22.0 Cocamidopropyl betaine 2.0 Sodium chloride 1.0 glycerin 2.5 water 72.5

The components are heated together with gentle stirring until homogeneous.

Example 16

A representative cleansing component comprising the following ingredients is prepared.

ingredient weight% Triethanolamine 2.9 Polyquaternium-39 0.1 Monolauryl phosphate 4.0 C ₁₂ -C ₁₄ N-methylglucosamide ¹ 5.0 Cocamidopropylhydroxysulfathane ² 2.0 Sodium decyl sulfate 0.5 Citric acid monohydrate 0.3 Spices, Preservatives & Others. 4.0 water 81.2

¹ Available from Hoechst Celanese

² Available in Rhone Poulenc

Add the components slowly at 60 ° C in the following order, until dissolved in water, respectively: TEA, lauryl phosphate, glucose amide. Cool to 45 &lt; 0 &gt; C and add sultaine, polyquaternium-39 and sulfate while stirring as described above. Add flavor and preservative and cool to room temperature.

Example 17

A typical cleansing component is prepared by mixing the following ingredients.

ingredient weight% Lauroylpolyglucose ¹ 20.0 Cetyltrimethylammonium bromide 4.0 Spices, Preservatives & Others 4.0 water 72.0

¹ Available as Henkel Plantaren 1200

Ⅱ. Therapeutic Efficacy Component

Examples 18-22

The following ingredients are mixed to produce representative skin conditioning ingredients.

ingredient Example 18 Example 19 Example 20 Example 21 Example 22 SEFA ^* Cotonate 48.0 75.0 33.5 40.0 80.0 SEFA ^* Behenate 12.0 25.0 8.4 10.0 10.0 Petrogradum 10.0 - 7.0 - - Glyceryl tribehenate 5.0 - 3.5 - - Stearyl alcohol - - - 5.0 - paraffin - - - 15.0 - Cholesterol ester 25.0 - 17.5 - - Ozokerite wax - - - - 10.0 glycerin - - 28.0 - - Triglyceryl monostearate - - 1.9 - - Decaglyceryl dipalmitate - - 0.2 - - Nonylphenol polyglycine ether ¹ - - - 30.0 -

^* SEFA is an acronym for sucrose esters of fatty acids.

¹ Hamplex TNP, Hampshire Chemical Co.

Examples 23-27

The following ingredients are mixed to produce representative skin conditioning ingredients.

ingredient Example 23 Example 24 Example 25 Example 26 Example 27 Petrolatum (white) 35.87 35.87 - - 34.0 Mineral oil 11.0 13.0 - - 10.0 Jojoba oil - - - 4.5 Pharma Liberty 10.0 9.0 - - Cocoa butter 5.0 Diisostearyl trimethylpropane siloxysilicate 20.0 20.0 - - Polydimethylsiloxane, 500 cSt Fluid - - 0.7 1.5 Decamethylcyclopentasiloxane - - - 16.5 Octamethylcyclotetrasiloxane - - - 10.0 Rubber polydimethylsiloxane - - 5.9 7.5 Stearyl methicone wax - - - 3.0 Polybutene - - - 4.5 Candelilla wax 4.6 4.6 - - 6.0 Paraffin wax - - - 15.0 2.0 Microcrystalline wax - - - 6.0 4.0 beeswax 3.0 3.0 - - 4.0 Ozokerite wax 6.0 6.0 - - Carnauba wax 3.0 3.0 - - Hydrogenated castor oil 0.50 0.50 4.0 - Silica - - - 4.5 Sodium magnesium silicate - - - 1.5 Tocopherol 0.03 0.03 - - Cyclomethicone - - 59.0 - Stearyl alcohol - - 25.5 - 9.0 Cetyl alcohol 9.0 Glyceryl stearate - - 2.6 - Acetylated monoglyceride 15.0 Diisostearyl maleate ¹ - - - 6.0 Glyceryl distearate - - - 9.5 glycerin - - - 6.0 water - - - 3.0 Nonylphenol polyglycine ether ² - - 5.0 - Undoped titanium dioxide 5.0 - - Octyl methoxycinnamate 5.0 - - - Fragrance & Others 1.0 1.0 1.0 1.0 2.0

¹ Eastman Chemical Co. As Myvacet 7-07, which is about half acetylated.

² Hampshire Chemical Co. Sold as Hamplex TNP

Example 28

The following ingredients are mixed to produce representative skin conditioning ingredients.

ingredient Example 28 Polydecene ¹ 53.3 Stearyl alcohol 7.7 12-hydroxystearic acid 13.5 Nonylphenol polyglycine ether 25.0 Octyl methoxycinnamate 1.5

¹ Puresyn 3000, Mobil Chemical Co.

Examples 29-31

The following ingredients are mixed to produce representative skin conditioning ingredients.

ingredient Example 29 Example 30 Example 31 glycerin 95.0 95.0 94.0 Decaglyceryl dipalmitate ¹ 5.0 1.0 5.0 Deceglyceryl dibehenate 4.0 Tribe henin 1.0

¹ Available from Lonza as Polyaldo 10-2-P

Examples 32-36

Representative conditioning components for the articles of the present invention are prepared in the following manner.

ingredient Example 32 Example 33 Example 34 Example 35 Example 36 Small Prize: SEFA ^* Cotonate 4.65 4.65 15.5 15.5 SEFA ^* Behenate 0.35 0.35 8.0 8.0 Tribe henin 6.0 6.0 Petrogradum 4.0 4.0 4.4 Cocoa butter 15.5 C ₁₀ -C ₃₀ cholesterol / lanosterol ester 13.0 13.0 C ₃₀ -C ₄₅ alkyl methicone ¹ Polyglyceryl-4 isostearate (and) cetyl dimethicone (and) hexyl laurate ² 5.0 5.0 PEG 30 dipolyhydroxy stearate ³ 3.0 Tetraglyceryl monostearate 2.1 Decaglyceryl dipalmitate 0.90 Ceresin wax 5.5 beeswax 7.0 Tablets lecithin 10.0 1-monostearin 10.0 Awards: glycerin 70.0 66.5 42.30 42.30 40.0 water 3.5 5.0 PVM / MA decadiene crosspolymer ⁴ 0.25 0.25 Sodium hydroxide (10% solution) 0.25 0.25 gelatin 2.6 Active skin care components: Panthenol 20.0 10.0 2.50 Nicotinamide 5.0 2.50 3.0 Element 5.0 2.50 2.50 Allantoin 0.20 0.20 Acetamidopropyltrimonium chloride 2.0

^* SEFA is an acronym for sucrose esters of fatty acids.

¹ Available in Dow Corning as AMS-C30

² Available as Abil WE-09 from Goldschmidt

³ Available in ICI as Arlacel P135

⁴ Available from ISP to Stabileze 06

Process for all emulsions:

The bovine aqueous phase is heated to 70 DEG C, the hydrophobic active skin care component is added and stirred until homogeneous. The hydrophilic active skin care component and the biodegradable component are premixed and, if necessary, heated slowly to dissolve or disperse them. These are gradually added to the small water phase and stirring is continued. Homogenize (high shear mixer, ultrasonic homogenizer, or high pressure homogenizer such as Microfluidizer from Microfluidics Corp.). Immediately apply to the surface of the substrate or cool rapidly from ice or ice water to room temperature. If necessary, store in a controlled environment under nitrogen for chemical stability.

Examples 37-41

Representative conditioning components are prepared as described in Examples 32-36, using the following components.

ingredient Example 37 Example 38 Example 39 Example 40 Example 41 Small Prize: SEFA ^* Cotonate 15.0 16.0 SEFA ^* Behenate 7.5 4.0 Tribe henin 6.0 Petrogradum 4.0 4.0 4.4 Cocoa butter 15.5 Polydecene ¹ 50.0 46.5 C10-C30 cholesterol / lanosterol ester 13.0 10.5 PEG 30 dipolyhydroxy stearate 3.0 3.0 Ceresin wax 5.5 Wax 7.0 Aluminum / magnesium hydroxystearate ^{2 in} mineral oil 7.5 C30-38 olefin / isopropyl maleate copolymer ³ 2.5 Polyethylene wax ⁴ 1.0 Tablets lecithin 10.0 Fragrances and other 1.0 1-monostearin 10.0 Awards: glycerin 30.0 25.0 34.80 20.0 38.0 water 8.0 8.0 5.0 PEG 2000 17.0 PVM / MA decadiene crosspolymer 0.25 Sodium hydroxide (10% solution) 0.25 gelatin 9.50 9.50 2.6 Active skin care components: Nicotinamide 2.50 Methanol in 50% beta cyclodextrin 2.50 Ascorbic acid (natural) 2.50 Tocopherol (natural) 1.00 2.50 Sorbitol 2.50 Lactic acid 2.5 Element 2.50 Allantoin 0.20 Triclosan 1.50 Chlorhexidine 0.50 Benzoyl peroxide 5.0 PPG 14 15% salicylic acid in butyl ether 12.0 Salicylic acid 2.5

¹ Mobil to Puresyn 3000

² Available in Giulini Chemie as Gilugel Min

³ Available from New Phase Technologies as Performa 1608

⁴ Available from New Phase Technologies to Performalene 400

Examples 42-46

Representative conditioning components are prepared as described in Examples 32-36 using the following components.

ingredient Example 42 Example 43 Example 44 Example 45 Example 46 Small Prize: SEFA ^* Cotonate 20.5 15.5 16.0 Mineral oil 7.50 SEFA ^* Behenate 8.0 8.0 8.0 Tribe henin 9.5 6.0 6.0 Petrolatum (white or super-white) 4.0 4.0 22.6 3.0 4.0 Candelilla wax 4.50 Paraffin wax 3.00 14.0 Microcrystalline wax 1.50 Wax 3.00 C10-C30 cholesterol / lanosterol ester 18.0 13.0 13.0 Lauryl methicone copolyol ¹ 5.0 Acetylated monoglyceride ² 11.3 Stearyl alcohol 6.8 Cetyl alcohol stearic acid 6.8 PEG 30 dipolyhydroxy stearate 4.5 3.0 Decaglyceryl dipalmitate ³ 0.90 Tetraglyceryl monostearate 2.10 Fragrance, other 1.0 3.0 2.0 Awards: glycerin 22.8 27.5 25.0 38.0 41.0 Decaglyceryl dipalmitate ³ 2.5 Calcium silicate microsphere ⁴ 15.0 Active skin care components: Guar hydroxypropyltrimonium chloride 1.00 Chitosan glycolate 2.50 Nicotinamide 1.50 2.50 2.50 0.2% Carbopol 940 aqueous solution, pH 6.0 38.0 Retinol 2.50 Pilot Triol ⁵ 1.00 Element 2.50 3.0 2.50 Vitamin C 2.50 Free Borage Oil 2.50 Ascorbyl palmitate 1.50 Acetamidopropyltrimonium chloride ⁶ 2.50

¹ Available as Dow Q2-5200 from Dow Corning

² Eastman Chemical Co. In Myvacet 7-07, which is about half acetylated

³ Available from Lonza as Polyaldo 10-2-P

⁴ Celite Co. From Celite C

⁵ Available from Henkel as Hydagen CMF

⁶ Available from Croda as Incromectant AQ

Example 43 : Glycerin is incorporated into the microspheres and then incorporated into the molten lipid and cooled or applied to the substrate during storage.

Examples 47-52

Representative conditioning components are prepared as described in Examples 32-36 using the following components.

ingredient Example 47 Example 48 Example 49 Example 50 Example 51 Example 52 Small Prize: SEFA ^* Cotonate 16.0 16.0 16.0 16.0 16.0 16.0 Mineral oil SEFA ^* Behenate 8.0 8.0 8.0 8.0 8.0 Tribe henin 6.0 6.0 6.0 6.0 6.0 6.0 Petrolatum (white or super-white) 4.0 4.0 4.0 4.0 4.0 4.0 C10-C30 cholesterol / lanosterol ester 13.0 13.0 13.0 13.0 13.0 13.0 Stearyl dimethicone 2.0 Dimethicone hydroxystearate 4.0 Dimethicone copolyol behenate 2.0 PEG 30 dipolyhydroxy stearate 3.00 3.00 Sodium lauroyl glutamate 2.00 Sodium stearoyl lactylate 2.00 Calcium stearate 5.0 Decaglyceryl dipalmitate 0.90 0.90 0.90 0.90 Tetraglyceryl monostearate 2.10 2.10 2.10 2.10 Fragrance, other 1.00 1.00 1.00 1.00 1.00 1.00 Awards: glycerin 44.5 42.5 35.5 35.5 25.0 43.0 75% polyethylene imine ^{1 in} water, pH 6.5 4.50 4.50 water 2.0 Decaglyceryl dipalmitate 2.50 2.50 Fumed silica 20.0 Propylene glycol alginate ² 2.0 Active skin care components: Nicotinamide 2.00 2.00 Chitosan 1.50 Green tea extract 4.50 Aloe vera gel 3.0 Vitamin C 2.50 Ascorbyl palmitate 2.00 2.50 Acetamidopropyltrimonium chloride 2.00 2.00

¹ Nippon Shokubai Co. Available as Epomin SP-018

Available as ² Kelco to Kelcoloid HVF

Examples 53-55

Representative conditioning components for the article of the present invention are prepared in the following manner.

ingredient Example 53 Example 54 Example 55 Small Prize: Tablet lecithin ¹ 15.4 10.3 10.8 Deccan 28.6 19.2 15.0 Mineral oil 5.0 Tricontanil PVP ² 26.0 Stearyl alcohol 13.0 12-hydroxystearic acid 19.4 Awards: glycerin 28.0 18.8 19.6 Propylene glycol 28.0 18.8 19.6 Active skin care components: Triclosan 0.20 Salicylic acid 0.40 Nicotinamide 4.0

¹ Available from Lucas Meyer as Epikuron 200

² ISP to Ganex WP-660

All components are agitated together until a microemulsion is formed. The skin care ingredients are added to a topcoat that best fits their solubility coefficient. When wax is added, it is slowly heated to the melting point of the wax, dispersed by stirring, applied to the substrate, cooled to room temperature and stored.

Examples 56-58

Representative conditioning components for the articles of the present invention are prepared according to the following manner.

ingredient Example 56 Example 57 Example 58 Small Prize: Isohexadecane 42.29 43.0 28.3 Sodium dioctyl sulfosuccinate ² 10.62 7.0 7.1 Awards: glycerin 35.17 19.0 23.6 water 11.72 19.0 7.8 Carnauba wax 29.0 gelatin 6.0 Active skin care components: Triclosan 0.20 Titanium Dioxide for Cosmetics 4.2 Undoped titanium dioxide 4.2 Salicylic acid 1.8

¹ Available from Lucas Meyer as Epikuron 2000

² Available as Aerosol OT from Pfaltz and Bauer

First, the skin care component is added to the phase that most closely matches their solubility coefficient. Subsequently, all components are agitated together until a microemulsion is formed. Coat on substrate surface.

Examples 59-64

Representative conditioning components for the articles of the present invention are prepared in the following manner.

Part A Example 59 Example 60 Example 61 Example 62 Example 63 Example 64 Sodium lauroyl ether sulfate (added as a SLES 27% active) 15.0 6.51 6.20 5.9 Cocamidopropyl betaine ¹ 13.5 5.85 5.57 5.82 5.19 5.3 Sodium lauroyl sarcosinate ² 1.35 0.60 0.57 6.01 5.36 0.54 Decyl polyglucose ³ 5.80 5.18 Lauryl alcohol 1.31 0.56 0.54 0.54 Polyethylene imine ⁴ 7.87 3.38 3.22 2.64 2.36 3.2 Citric acid (added in 50% aqueous solution) 0.32 0.11 0.11 0.09 Tetrasodium EDTA 0.28 Sulfuric acid 5.4 2.37 2.25 2.2 Preservative, fragrance 0.62 0.45 0.43 2.86 2.55 0.3 Sodium sulfate 7.9 3.47 3.21 3.0 glycerin 26.45 56.7 46.4 44.1 39.36 44.8 Sorbitol 5.0 SEFA ^* Cotonate 12.8 SEFA ^* Behenate 8.0 Part B - Polymer gelling agent gelatin 4.2 Polyacrylamide and isoparaffin ⁵ 7.5 Polyurethane latex in 50% isopropanol ⁶ 34.1 Polyacrylate Copolymer ⁷ 7.5 Polystyrene sulfonate copolymer ⁸ 1.1 Chitosan lactate 5.4 Part C - Physical Gelling Agent 12-hydroxystearic acid 10.0 10.66 Stearyl alcohol 10.0 20.0 20.0 7.11 15.0

^* SEFA is an acronym for sucrose esters of fatty acids.

¹ Available from Goldschmidt to Tegobetaine F

² Hamposyl L-30 (type 721), 31% active at Hampshire Chemical

³ Available as Henkel Plantaren 2000NP

⁴ Nippon Shokubai Co. Epomin SP-018 with a molecular weight of about 1,800

⁵ Available from BF Goodrich as Carbopol Ultrez

⁶ commercially available as Sancure 2710 made from a prepolymer containing about 20% polymer, 30% water, 50% IPA in BF Goodrich

⁶ Seppic Corp. From Sepigel 305

⁷ Available as AQ38S from Eastman Chemical

The surfactant and fatty alcohol are combined with a low speed impeller mixer while heating to 65 占 폚. Heat is removed and allowed to cool to 65 ° C while continuing to mix. The cationic polymer is added and stirred until homogeneous. The remaining Part A is slowly added with stirring. Homogenized to disperse the SEFA as an emulsion. Titrate with concentrated sulfuric acid until the pH reaches about 6.5. The Part A composition is spread on a tray and dried in a suitable (vacuum or convection) oven at a temperature not exceeding 65 캜 until substantially no water remains to produce a dry mixture. The dried Part A component is combined with the polymeric gelling agent of Part B and heated to dissolve or disperse. The resulting composition is combined with a physical gelling agent. The gelling agent is melted and dissolved in the composition by heating. Apply to substrate surface (s) or cool to room temperature and store.

Examples 65-70

Representative conditioning components for the articles of the present invention are prepared as described in Examples 59-64 using the following components.

Part A Example 65 Example 66 Example 67 Example 68 Example 69 Example 70 Sodium lauroyl sarcosinate ¹ 8.87 11.4 10.8 10.8 Polyethylene imine ² 7.39 7.50 7.50 9.5 9.0 9.0 water 4.43 3.00 3.00 5.7 5.4 5.4 Sulfuric acid 6.36 QS QS 8.1 7.7 7.7 Fragrance, other glycerin 34.45 52.5 45.0 41.3 39.25 34.25 Propylene glycol 2.50 Element 2.50 2.50 2.0 1.9 1.9 Panthenol 2.0 1.9 1.9 Nicotinamide 2.50 2.50 2.0 1.9 1.9 Salicylic acid Polymethylsilsesquioxane ³ 4.20 4.20 Pearl polish mica 3.85 3.85 Stearyl methicone wax 5.0 SEFA Cotonate 5.0 Petrogradum 5.0 Part B - Polymer gelling agent gelatin 0.1 Polyacrylamide and isoparaffin ⁴ 16.0 12.0 12.0 Part C - Physical Gelling Agent 12-hydroxystearic acid 12.0 12.0 10.5 Carnauba wax 18.0 14.1 14.1 Stearyl alcohol 8.0 8.0 7.0

¹ sold as dry Hamposyl L-95 in Hampshire Chemical

² Nippon Shokubai Co. As Epomin SP-018 with a molecular weight of about 1,800

³ Kobo. Inc. Sold as Tospearl 145A

⁴ Seppic Crop. From Sepigel 305

Examples 71-74

Representative skin conditioning ingredients comprising the following ingredients are prepared.

ingredient Example 71 Example 72 Example 73 Example 74 SEFA ^* Cotonate 62.0 52.0 Petrogradum 4.5 Stearyl alcohol 4.0 Stearic acid 3.0 lanolin 20.0 13.0 Ethylene Vinyl Acetate Polymer ¹ 10.0 10.0 Polydecene ² 2.0 2.0 Sodium lauroyl sarcosinate ³ 25.0 3.00 3.0 Lauryl betaine ⁴ 1.50 2.0 Lauroamphoacetate ⁵ 5.25 Sodium laureth-3 sulfate ⁶ 10.5 Cocamid MEA ⁷ 2.80 Sulfuric acid QS Guar hydroxypropyltrimonium chloride 0.50 0.50 Cholesterol ⁸ 9.0 1.0 Nonylphenol polyglycine ether ⁹ 5.0 Undoped titanium dioxide 4.0 Octyl methoxycinnamate 4.0 Nicotinamide 2.5 glycerin 10.0 3.00 water 48.5 55.95 PEG6 caprylic / capric acid glyceride 3.40 Soybean oil 1.50 Deodorized soybean oil 8.0 Palm oil fatty acid 2.60 Polyquaternium-10 0.40 Fragrance, preservative, etc. 4.60

^* SEFA is an acronym for sucrose esters of fatty acids.

¹ Available in DuPont as Elvax 40W

² Mobil to Puresyn 3000

³ For example, commercially available as Hamposyl L95 (solid) or L30 (30% active in water) in Hampshire Chemical

⁴ Available from Albright & Wilson as Empigen BS98 (80% betaine, 20% salt)

⁵ Available in Albright & Wilson as Empigen CDL60

⁶ Available in Albright & Wilson as Empigen ESC3

⁷ Available from Albright & Wilson as Empigen CME / G

⁸ Available from Croda as Super Hartolan

⁹ Hampshire Chemical Co. Sold as Hamplex TNP

The lipid components are melted, water (if applicable) and wetting agent (s) are added, and the heating and stirring are continued until the surfactant is added and homogenized. Cool to room temperature and add the skin care active (s) and deposition agent (s). Adjust the pH to about 7.0 with sulfuric acid. Spray, roll, dip or otherwise apply to the substrate and dry (if water is included) before packaging.

Ⅲ. Personal care articles

Example 75

A representative skin cleansing article is prepared in the following manner.

4 g of the cleansing component of Example 11 is applied to one side of a fusible web comprising a low melt heat sealable polyamide fibers. The permeable mesh is produced by Pellon and supplied by H. Levinson & (Chicago, IL). Apply the cleansing composition to an oval area of about 13 cm x 18 cm. The cleansing ingredients are air dried. A layer of 2 oz / sq yd polyester betting cut to the same size as the net is placed over the convergence network. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The nonwoven layer is placed under the fusing netting to form the second side of the article. The nonwoven is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is hydrated and punched to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. The shape of the article is an ellipse of about 122 mm x 160 mm. A heat-sealing mold using a pressure-platen heat sealer such as a Sentinel Model 808 heat sealer available from Sencorp (Hyannis, Mass.) Is used to seal the layers together in a grid pattern using point bonds. Point bonds are measured with diameters of about 4 mm each, and about 51 individual seams are uniformly distributed. You can use it soon after you trim it.

Example 76

A representative skin cleansing article is prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the web and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines was formed on each side of the net, Continuous extrusion through a coating head is applied to one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing per silver finished article is 4.4 grams of the ingredient. The substrate is a spunlace mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, hydroapertured to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second web of air infused loftable low density bet is continuously injected over the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. The net is cut into individual articles about 120 mm x 160 mm rectangular in size with rounded corners, with a total of about 51 seals per item.

Example 77

Representative skin cleansing and conditioning products are prepared in the following manner.

Three grams of the skin conditioning composition of Example 34 is applied on each side of the finished article of Example 75 on each side in half. The composition is applied by half-slot coating the composition on each side of the article, uniformly on the surface of the article, with the composition being a hot liquid (60-70 DEG C).

Example 78

Representative skin cleansing and conditioning products are prepared in the following manner.

Three grams of the skin conditioning composition of Example 18 is applied on each side of the finished article of Example 75 in half. The composition is applied by half-slot coating the composition on each side of the article, uniformly on the surface of the article, with the composition being a hot liquid (60-70 DEG C).

Example 79

Representative skin cleansing and conditioning products are prepared in the following manner.

Three grams of the skin conditioning composition of Example 65 is applied on each side of the finished article of Example 75 in half. The composition is applied by half-slot coating the composition on each side of the article, uniformly on the surface of the article, with the composition being a hot liquid (60-70 DEG C).

Example 80

Representative skin cleansing and conditioning products are prepared in the following manner.

Three grams of the skin conditioning composition of Example 34 is applied on each side of the finished article of Example 76 on each side in half. The composition is applied by half-slot coating the composition on each side of the article, uniformly on the surface of the article, with the composition being a hot liquid (60-70 DEG C).

Example 81

Representative skin cleansing and conditioning products are prepared in the following manner.

Three grams of the skin conditioning composition of Example 18 is applied on each side of the finished article of Example 76 on each side in half. The composition is applied by half-slot coating the composition on each side of the article, uniformly on the surface of the article, with the composition being a hot liquid (60-70 DEG C).

Example 82

Representative skin cleansing and conditioning products are prepared in the following manner.

Three grams of the skin conditioning composition of Example 65 is applied on each side of the finished article of Example 76 on each side in half. The composition is applied by half-slot coating the composition on each side of the article, uniformly on the surface of the article, with the composition being a hot liquid (60-70 DEG C).

Example 83

A representative skin cleansing article is prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second web of air infused loftable low density bet is continuously injected over the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Cut the net with individual items of approximately 120 mm x 480 mm rectangular size with rounded corners.

Example 84

A representative skin cleansing article is prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second substrate network, air infused loftable low density betting, is continuously injected over the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A third substrate network identical to the second substrate network is continuously injected through the second substrate network and placed in contact with the second substrate. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Cut the net with individual items of approximately 120 mm x 90 mm rectangle size with rounded corners.

Example 85

A representative skin cleansing article is prepared in the following manner.

Four grams of the cleansing component of Example 12 is applied to one side of a transmissive fusible web comprising low melt heat-resistant synthetic polyamide fibers. The permeable mesh is produced by Pellon and supplied by H. Levinson & (Chicago, IL). Apply the cleansing composition to an oval area of about 13 cm x 18 cm. The cleansing ingredients are air dried. A layer of 2 oz / sq yd polyester betting cut to the same size as the net is placed over the convergence network. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting has an air permeability of about 1270 cfm / ft ² and a foam permeable crystal pressure of about 2.7 cm H ₂ O. The betting is considered to be thermally bonded without the use of adhesives. The nonwoven layer is placed under the fusing netting to form the second side of the article. The nonwoven is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is hydrated and punched to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. The shape of the article is an ellipse of about 122 mm x 160 mm. A heat-sealing mold using a pressure-platen heat sealer such as a Sentinel Model 808 heat sealer available from Sencorp (Hyannis, Mass.) Is used to seal the layers together in a grid pattern using point bonds. Point bonds are measured with diameters of about 4 mm each, and about 51 individual seams are uniformly distributed. You can use it soon after you trim it.

Examples 86 to 88

With the cleansing ingredients of Examples 1, 2 and 5, representative skin cleansing products are prepared in the following manner.

With four quadrants forming a rectangle of about 10 inches by 12 inches, leaving a space between the edges and the quadrant so that the layer is sealed without the surfactant, 8 grams of the cleansing component is applied to the permeable fusion network On one side. The permeable mesh is a fibrous low density polyethylene (LDPE or LLDPE) material that is usually marketed by the sewing supplier. A layer of 4 oz / sq yd polyester betting cut to the same size as the net is placed over the convergence network. The polyester bets have a basis weight of 4 oz / yd ² , are composed of polyester fibers of about 30 microns in average diameter and are bonded together as adhesives, for example, Mountain Mist Extra Heavy Batting # 205 from Stearns Textiles (Cincinnati, OH) Lt; / RTI &gt; A fibrous nonwoven layer having a basis weight of about 65 gsm and a hydrated textile mixture of 55% cellulose and 45% polyester (commercially available as Technicloth II from The Texwipe Company of Saddle River, NJ) . A thermal suture mold using a pressure platen thermal sealer such as the Sentinel Model 808 thermal sealer available from Sencorp (Hyannis, Mass.), In which the batting melts and flows into the first layer to form a rectangle at a temperature and pressure sufficient to form the proper seal The layers are sutured together in the form of a windowpane, usually about 370 degrees Fahrenheit and 30 psi mechanical suture for 6 to 10 seconds. The suture is continuous around the edges and has a single pane of curved circle that represents a width of about 2 mm in each X- and Y-direction. After cooling, trim the items, make the corners round, and keep them until use.

Examples 89 to 90

With the cleansing component powders of Examples 3 and 4, representative skin cleansing and conditioning products are prepared in the following manner.

4 grams of the dry cleansing component powder is applied to one side of the permeable fusing net including the low melt heat sealing synthetic fibers. The permeable mesh is produced by Pellon and supplied by H. Levinson & (Chicago, IL). Spray the powder uniformly on the ellipsoid of about 17 cm x 19 cm. A layer of 2 oz / sq yd polyester betting cut to the same size as the net is placed over the convergence network. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting has an air permeability of about 1270 cfm / ft ² and a foam permeable crystal pressure of about 2.7 cm H ₂ O. The betting is considered to be thermally bonded without the use of adhesives. A second nonwoven layer is prepared, which includes an apertured apertured, polypropylene scrim about 10 microns in diameter, woven within about 0.8 centimeters and having a fiber diameter of about 150 microns inside. The second layer is cut larger than the required article axis so that the X- and Y-axes of the layer are reduced to about 70 percent of their original size and the layer is about 0.12 in. Is placed in a convection oven for about 10 minutes at a temperature of about 150 degrees Celsius until it has a macroscopic thickness of about &lt; RTI ID = 0.0 &gt; The layer has a macroscopic average basis weight of about 64 gsm and a pore size of about 0.5 mm average diameter before shrinkage. The second layer is placed under the fusing net, the layers are sealed together with point bonds, and the perforations are closed with a heat sealing mold using a pressure platen heat sealing device such as the Sentinel Model 808 heat sealer available from Sencorp (Hyannis, MA) Suture about 2 mm wide. Point bonds each have a diameter of about 3 mm, and about 51 individual seams are uniformly distributed. 2.5 grams of the skin conditioning composition of Example 25 is applied to the loftable batting surface of the article by pouring the composition through a slotted rolling device with trimmed articles, an infusion reservoir maintained at about 60 DEG C and a mechanized 1.5 mm gap . The composition is rapidly cooled on the article surface and stored in a sealed metallized film package until use.

Examples 91 to 96

Representative skin cleansing and conditioning articles with the liquid cleansing ingredients of Examples 6, 8, 9, 15, 16 and 17 are prepared in the following manner.

The liquid cleansing component is coated with a brush in the form of a window glass except for the edges and the sealing position until 2 grams of the solid cleansing component is applied and applied to one side of the first substrate. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. The substrate is air dried in a convection oven at 45 캜 for about 6 hours or until dry when touched. A second substrate, which is an infused loftable low density bet, is placed on the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A thermal suture mold using a pressure platen thermal sealer such as the Sentinel Model 808 thermal sealer available from Sencorp (Hyannis, Mass.), In which the batting melts and flows into the first layer to form a rectangle at a temperature and pressure sufficient to form the proper seal The layers are sutured together in the form of a windowpane, and mechanical pressure sutures of approximately 370 degrees Fahrenheit and 30 psi are usually sufficient for 6 to 10 seconds. The suture is continuous around the edges and has a single pane of curved circle that represents a width of about 2 mm in each X- and Y-direction. After cooling, the article was trimmed, the composition was injected through a slotted rolling apparatus having a mechanized 1.5 mm gap and an infusion reservoir maintained at about 60 DEG C, to deliver 3 grams of the skin conditioning composition of Example 26 to the loftable batting surface of the article Lt; / RTI &gt; The composition is rapidly cooled on the article surface and stored in a sealed metallized film package until use.

Examples 97 to 102

With the liquid cleansing ingredients of Example 7 and the skin conditioning compositions of Examples 19 to 24, representative skin cleansing and conditioning products are prepared in the following manner.

Four strips of liquid cleansing composition are successively extruded onto the first movable web of air infused loftable low density betting. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The liquid cleansing component is heated to the melting point and stored in a reservoir at about 65 ° C. and pumped into an extrusion head that continuously meters four cylindrical strands on a net, which is a uniform distance across the net, to provide about 5 grams of composition per finished article Lt; / RTI &gt; The second net, which is a film formed in the micro-perforated and macro-perforated film formed in U.S. Patent No. 4,629,643, is continuously injected onto the surface of the first net on the bump and the cleansing component side, the macropore protruding side. The skin conditioning composition is uniformly slot coated on the exposed betting surface in the hot state at a rate of about 3 grams per finished article, cooled on the article surface and allowed to solidify. The web is continuously sutured and cut into approximately 120 mm x 160 mm rectangles with rounded corners using heated metal rolls and pressure rolls applied to the surface of the formed film. Pack the item until you use it.

Examples 103-105

With the liquid cleansing ingredients of Example 6 and the skin conditioning compositions of Examples 56, 57 and 58, representative skin cleansing and conditioning products are prepared in the following manner.

The liquid cleansing component is coated with a brush in the form of a window glass except for the edges and the sealing position until two grams of the solid surfactant is applied and applied to one side of the first substrate. The substrate is a polyester batting with a basis weight of 2 oz / yd ² and comprises a mixture of about 23 microns and 40 microns average diameter fibers, some of which are wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. Dry the cleansing ingredients. A second substrate, a high loft strength, adhesive bonded cellulose paper towel with excellent loft and a basis weight of about 53 gsm, is placed over the exposed surface of the cleansing component of the batting. A useful towel was manufactured by The Procter & Gamble Company, which retains its Z-direction height when wet and has a thickness of about 0.047 inches at 5 gsi and a loft / soft ratio of about 1.28, . Seal the layers together in a rectangular pane of glass at a temperature and pressure sufficient to form a suitable seal with a thermal suture mold using a pressure platen thermal sealer such as the Sentinel Model 808 thermal sealer commercially available from Sencorp (Hyannis, Mass.). And have a single window sill intersecting circle that is approximately 2 mm wide in each X- and Y-direction. 1.5 grams of the skin conditioning composition is applied to the loftable batting surface of the article by pouring the composition through a slotted rolling device with trimmed articles, an injection reservoir maintained at about 60 DEG C and a mechanized 1.5 mm gap. The composition is rapidly cooled on the article surface and stored in a sealed metallized film package until use.

Example 106

Representative skin cleansing and conditioning products are prepared in the following manner.

The cleansing component of Example 12 was measured by measuring the width across the net and was divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines was formed on each side of the net, And is continuously extruded to be applied to one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second substrate network, air infused lofty low density betting, is continuously injected over the first substrate and placed in contact with the surfactant layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A third substrate network identical to the second substrate network is continuously injected through the second substrate network and placed in contact with the second substrate. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. The skin conditioning liquid of Example 53 is sprayed onto the web at a rate of about 25 gsm per side or about 0.5 gram of the composition per finished article. The net is cut into individual pieces of approximately 120 mm x 90 mm rectangular size with rounded corners and packed until use.

Examples 107-108

Using the skin conditioning compositions of Examples 54 and 55, representative skin cleansing and conditioning products are prepared in the following manner.

The low water activity cleansing component of Example 2 was mixed with an aluminosilicate (which generates heat due to an exothermic reaction when exposed to water and is available from The PQ Corporation of Valley Forge, PA as Advera 401 N) It is pulverized into three rolls at a ratio of 1: 1. 10 grams of the cleansing composition is applied to one side of the batting layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. Surfactants are applied to the fibers in four quadrants, leaving a space between the edges and quadrants so that the layer is sealed without a surfactant, forming a rectangle of about 10 inches by 12 inches. (Bonded) fibers having a fiber diameter of about 100 microns across the width of the nonwoven fabric and about 250 microns perpendicular to the width, and having a fiber diameter of about 10 microns, A second nonwoven layer comprising the dead scrim is produced. The scrim is commercially available from Conwed plastics (Minneapolis, MN). The second nonwoven has a basis weight of about 70 gsm and is slightly wrinkled due to the net elongation and subsequent relaxation of the elongation during the production of the nonwoven. Layer is sealed with a point bond and a perimeter about 2 mm wide with a heat seal mold using a pressure platen thermal sealer such as Sentinel Model 808 heat sealer available from Sencorp (Hyannis, Mass.). Point bonds each have a diameter of about 3 mm, and about 51 individual seams are uniformly distributed. 4 grams of the skin conditioning composition is applied to the loftable batting surface of the article by pouring the composition through a slotted rolling device with trimmed articles, an injection reservoir maintained at about 60 DEG C and a mechanized 1.5 mm gap. The composition is rapidly cooled on the article surface and stored in a sealed metallized film package until use.

Examples 109 to 116

Using the skin conditioning compositions of Examples 59, 60, 61, 62, 63, 68, 69 and 70, representative skin cleansing and conditioning products are prepared in the following manner.

Four grams of the cleansing component of Example 11 is uniformly sprayed by hand over the loftable batting. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A fibrous nonwoven layer having a basis weight of about 65 gsm and a hydrated textile mixture of 55% cellulose and 45% polyester (available as Technicloth II from Texwipe Company, Saddle River, NJ) Plane. The layers are sutured together using an interlocking suture plate using a non-heated plate with an inverted thimble-shaped reservoir uniformly distributed in a hexagonal lattice pattern. The thimble reservoir is about 1.2 cm in diameter at the base and about 2 cm from the center-center lobe. The land portions between the dimples on the non-heated plate are concave to a few millimeters to form troughs connected to each other. The heating plate has an external ridge that exactly fits over the land portion of the non-heated plate. The heating plate is contacted with a cellulose / polyester substrate and heat sealed using a pressure platen thermal sealer such as Sentinel Model 808 thermal sealer commercially available from Sencorp (Hyannis, MA). The resulting unfinished article has a more pronounced thimble shape with the batting surface elevated and a shorter dimple or " button " with the cellulose / polyester substrate surface of the article up, and both sides are easy to grasp. Cut the article into a rectangle approximately 120 mm x 160 mm. Three grams of the skin conditioning composition per article is pipetted to the skin region during the hot period of the composition, allowed to cool and solidify. Pack the item until you use it.

Example 117

Representative skin cleansing and conditioning products are prepared in the following manner.

Example 8 The liquid cleansing component of Example 10 Cleansing Ingredient 8 grams was divided into four quadrants, forming a rectangle about 10 inches x 12 inches, leaving a space between the edges and quadrants so that the layer was sealed without a surfactant, &Lt; / RTI &gt; on one side of a transmissive fusing net. The permeable mesh is a fibrous low density polyethylene (LDPE or LLDPE) material that is usually marketed by the sewing supplier. The composition is dried. A layer of 4 oz / sq yd polyester betting cut to the same size as the net is placed over the convergence network. The polyester bets have a basis weight of 4 oz / yd ² , are composed of polyester fibers of about 30 microns in average diameter and are bonded together as adhesives, for example, Mountain Mist Extra Heavy Batting # 205 from Stearns Textiles (Cincinnati, OH) Lt; / RTI &gt; A fibrous nonwoven layer having a basis weight of about 65 gsm and a hydrated textile mixture of 55% cellulose and 45% polyester (commercially available as Technicloth II from Texwipe Company (Saddle River, NJ)) is placed under the convergence net. A thermal suture mold using a pressure platen thermal sealer such as the Sentinel Model 808 thermal sealer available from Sencorp (Hyannis, Mass.), In which the batting melts and flows into the first layer to form a rectangle at a temperature and pressure sufficient to form the proper seal The layers are sutured together in the form of a windowpane, usually about 370 degrees Fahrenheit and 30 psi mechanical suture for 6 to 10 seconds. The suture is continuous around the edges and has a single pane of curved circle that represents a width of about 2 mm in each X- and Y-direction. Five grams of the conditioning composition of Example 64 is applied with a brush on each side of the article in half, and the article is dried again. Trim the item, make the corner round, and keep it until use.

Examples 118-119

Using the skin cleansing compositions of Examples 66 and 67, representative skin cleansing and conditioning products are prepared in the following manner.

The liquid cleansing component of Example 15 is applied to the first substrate by immersing the 120 mm x 160 mm cut surface of the substrate into the composition container until the weight increases to about 8 grams. The substrate is a polyester batting with a basis weight of 2 oz / yd ² , comprising a fiber mixture of about 23 microns and 40 microns average diameter, with at least a portion of it wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The substrate is dried. With a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive to form a hole with a diameter of about 2 mm and a piece of a second substrate having a basis weight of about 70 gsm, Lt; / RTI &gt; The substrates are sutured together using an ultrasonic suture which sutures with a dot pattern containing a grid of 4 mm diameter sealing points uniformly distributed throughout the article. Four grams of the skin conditioning composition is applied uniformly over both sides of the article by injecting the composition through a slotted rolling apparatus having an injection reservoir maintained at about 60 DEG C and a mechanized 1.5 mm gap. The composition is rapidly cooled on the article surface and stored in a sealed metallized film package until use.

Examples 120 to 124

Using the skin conditioning compositions of Examples 27 to 31, representative skin cleansing and conditioning products are prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second substrate network, air infused, loftable low density polyester betting, is continuously injected over the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A third substrate network identical to the second substrate network is continuously injected through the second substrate network and placed in contact with the second substrate. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Slot coating the skin conditioning composition from both sides of the substrate (about 140 gsm per side) at a rate equal to 3 grams of the skin conditioning composition per finished article from the hot reservoir pumped through the slot dye, Allow the cooling fan to pass through to cool quickly on the surface. Cut the net with individual items of approximately 120 mm x 90 mm rectangle size with rounded corners.

Examples 125-145

Using the skin conditioning compositions of Examples 32 to 52, representative skin cleansing and conditioning products are prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second substrate network, air infused loftable low density betting, is continuously injected over the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A third substrate network identical to the second substrate network is continuously implanted over the second substrate and placed in contact with the second substrate. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Slot coating the skin conditioning composition from both sides of the substrate (about 140 gsm per side) at a rate equal to 3 grams of the skin conditioning composition per finished article from the hot reservoir pumped through the slot dye, Allow the cooling fan to pass through to cool quickly on the surface. Slot coating reservoirs are continuously mixed to maintain the stability of the emulsion. Cut the net with individual items of approximately 120 mm x 90 mm rectangle size with rounded corners.

Examples 146 to 147

Using the skin cleansing and conditioning compositions of Practice 71 and 74, representative skin cleansing and conditioning products are prepared in the following manner.

The first substrate and the second substrate are cut into a rectangle approximately 12 inches by 9 inches. The first substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form holes with a diameter of about 2 mm and a basis weight of about 70 gsm. The second substrate is a polyester batting with a basis weight of 2 oz / yd ² , comprising a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of it wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A thermal suture mold using a pressure platen thermal sealer such as the Sentinel Model 808 thermal sealer available from Sencorp (Hyannis, Mass.), In which the batting melts and flows into the first layer to form a rectangle at a temperature and pressure sufficient to form the proper seal Suture the substrates together in the form of a windowpane, usually about 370 degrees Fahrenheit and 30 psi mechanical suture for 6 to 10 seconds. The suture is continuous around the edges and has a single pane of curved circle that represents a width of about 2 mm in each X- and Y-direction. After cooling, the article is trimmed to approximately 11 inches x 8.5 inches and 10 grams of the skin cleansing and conditioning composition is applied to the outer surface of both sides, about half of the composition per side. The composition is dried and stored until use.

Examples 148-149

Using the skin cleansing and conditioning compositions of Examples 72 and 73, representative skin cleansing and conditioning products are prepared in the following manner.

The first substrate and the second substrate are cut into a rectangle of about 12 inches by 9 inches. The first substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form holes with a diameter of about 2 mm and a basis weight of about 70 gsm. The second substrate is a polyester batting with a basis weight of 2 oz / yd ² , a polyester batting comprising a fiber mixture of about 23 microns and 40 microns average diameter, and at least some of which is wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A thermal suture mold using a pressure platen thermal sealer such as the Sentinel Model 808 thermal sealer available from Sencorp (Hyannis, Mass.), In which the batting melts and flows into the first layer to form a rectangle at a temperature and pressure sufficient to form the proper seal Suture the substrates together in the form of a windowpane, usually about 370 degrees Fahrenheit and 30 psi mechanical suture for 6 to 10 seconds. The suture is continuous around the edges and has a single pane of curved circle that represents a width of about 2 mm in each X- and Y-direction. After cooling, the article is trimmed to about 11 inches x 8.5 inches and 8 grams of the skin cleansing and conditioning composition is applied to the heating reservoir, pump, on-off valve, slot head, An XY table, a programmable controlled metrology system that includes a control system, is slot coated on the article at 4 grams per side so as to be evenly distributed on the surface of the article. The composition is rapidly cooled on the surface of the article. Pack the item until you use it.

Examples 150 - 152

Representative skin cleansing and conditioning products are prepared in the following manner.

A liquid cleansing component comprising the following ingredients is prepared:

ingredient Example 150 Example 151 Example 152 Sodium laureate 3 sulfate 3.60 Sodium C13 / C14 methyl branched chain sulfate 5.00 5.60 4.50 Sodium paraffin sulfonate 6.40 Sodium alpha olefin sulphonate 5.20 Sodium lauryl sulfate 5.50 Sodium lauroamphoacetate 4.50 5.30 3.65 Cocamide MEA 3.55 3.20 2.80 Suche mountain 2.80 5.70 6.00 Sodium succinate 0.10 0.14 0.30 Citric acid 3.00 4.30 5.00 Sodium citrate 1.60 1.10 1.40 Malonic acid 4.00 2.20 glycerin 10.00 15.00 8.50 12-18 palm oil 2.00 3.00 Spices 1.00 1.20 1.00 MgSO ₄ -7H ₂ O 0.89 0.90 0.80 water 54.21 47.61 52.25 Salicylic acid 1.85 Triclosan 0.25 Trichlorocarbonylide 1.10 Zinc pyrithione 2.00

The cleansing component is applied to one side of the first substrate by brushing on one side of the substrate until 10 grams of the composition is added to the 11 inch by 8.5 inch cuts. The substrate is a polyester batting with a basis weight of 2 oz / yd ² , comprising a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of it wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The first substrate is dried. The second substrate is thinned on the untreated surface of the first substrate using an ultrasonic suturing machine which sutures with a dot pattern including a grid of 4 mm diameter sealing points uniformly distributed at intervals of 2 cm across the screen. The second substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form about 2 mm diameter holes and has a basis weight of about 70 gsm. The skin conditioning composition of Example 19 was slot coated uniformly over the entire surface of the second substrate at a rate of about 3 grams per article, cooled, and packaged until use. The article is endowed with antibacterial activity against persistent antiviral, antifungal, and gram-negative and gram-positive microorganisms, is well foamed, and relatively mild to the skin.

Example 153

Representative skin cleansing and conditioning products are prepared in the following manner.

Four grams of the cleansing component of Example 11 is uniformly hand-sprinkled throughout the loft batting. The betting is carried out using a Stevens Textiles (Cincinnati, OH) with polyester bets of 4 oz / sq yd, containing polyester fibers of about 30 microns average diameter, cut into 130 mm x 175 mm, In Mountain Mist Extra Heavy Batting # 205. A fibrous nonwoven layer having a basis weight of about 65 gsm and a hydrated textile mixture of 55% cellulose and 45% polyester (commercially available as Technicloth II from Texwipe Company (Saddle River, NJ)) was applied to the surface of the surfactant coating . The layers are sutured together using an interlocking suture plate using a non-heated plate with an inverted thimble reservoir uniformly distributed in a hexagonal lattice pattern. The thimble reservoir is about 1.2 cm in diameter at the base and 1.5 cm from the center-center lobe. The land portion between the dimples on the non-heated plate is piled up several millimeters, forming a ridge connected to each other. The heating plate has an outer curve that exactly fits the ridge of the non-heated plate. The heating plate is contacted with a cellulose / polyester substrate and heat sealed using a pressure platen thermal sealer such as Sentinel Model 808 thermal sealer commercially available from Sencorp (Hyannis, MA). The resulting incomplete article has a three-dimensional feature on both sides that facilitates foaming and slips along the surface of the skin while being held in use. Cut the article into a rectangle approximately 120 mm x 160 mm.

A skin conditioning inverse emulsion paste for use with the article is prepared as follows:

ingredient percent PEG 30-dipolyhydroxy stearate 3.0 SEFA Cotonate 20.0 Petrogradum 4.0 Tribe henin 5.0 C10-C30 cholesterol / lanosterol ester 13.0 SEFA Behenate 5.0 glycerin 50.0

The fat soluble component is heated to &lt; RTI ID = 0.0 &gt; 70 C &lt; / RTI &gt; Glycerin is slowly added with vigorous stirring. The composition is homogenized. Skin Conditioning 3 grams of inverse emulsion paste is pipetted into the pressed area on the cellulose / polyester side of the article in a hot state. The composition is quickly cooled with a semi-solid paste. Pack the item until you use it.

Examples 154 to 158

Using the skin conditioning compositions of Examples 19, 29, 34, 55 and 60, representative skin conditioning products are prepared in the following manner.

The conditioning composition was applied to four lines separated by a distance of 20 mm, 40 mm and 20 mm, measuring width across the net, each 5 mm wide, and coated with a pair of parallel lines on each side of the net And then continuously extruded through the head to be coated on one side of the first substrate. The composition is extruded at a rate such that the composition per finished article is 3 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second net of air infused loftable low density betting is continuously injected over the first substrate and placed in contact with the first substrate on the side not containing the skin conditioning composition. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. The net is cut into individual articles about 120 mm x 160 mm rectangular in size with rounded corners, with a total of about 51 seals per item.

Examples 159 to 163

Using the skin conditioning compositions of Examples 19, 28, 34, 55 and 69, representative skin conditioning articles are prepared in the following manner.

The conditioning composition was applied to four lines separated by a distance of 20 mm, 40 mm and 20 mm, measuring width across the net, each 5 mm wide, and coated with a pair of parallel lines on each side of the net And then continuously extruded through the head to be coated on one side of the first substrate. The composition is extruded at a rate such that the composition per finished article is 1.1 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second net of air infused loftable low density betting is continuously injected over the first substrate and placed in contact with the first substrate on the side not containing the skin conditioning composition. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. The net is cut into individual articles of approximately 120 mm x 90 mm rectangular size with rounded corners, with a total of about 51 seals per item. The article is convenient to apply to narrower areas of the skin, such as the face, elbow, neck and / or feet.

Example 164

A representative skin cleansing article is prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing component is extruded at a rate such that the cleansing component per finished article is 0.40 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second substrate network, air infused lofty low density betting, is continuously injected over the first substrate and placed in contact with the surfactant layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A third substrate network identical to the second substrate network is continuously injected through the second substrate network and placed in contact with the second substrate. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Cut the net with individual items of approximately 120 mm x 90 mm rectangle size with rounded corners.

Examples 165 to 169

Using the skin conditioning compositions of Examples 19, 28, 34, 55 and 69, representative skin cleansing and conditioning products are prepared in the following manner.

The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing component is extruded at a rate such that the cleansing component per finished article is 0.52 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second substrate network, air infused lofty low density betting, is continuously injected over the first substrate and placed in contact with the surfactant layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. A third substrate network identical to the second substrate network is continuously injected through the second substrate network and placed in contact with the second substrate. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Slot coating of the skin conditioning composition on both sides of the substrate (approximately 55 gsm per side) at a rate equal to 1.25 grams of the skin conditioning composition per finished article from the hot reservoir pumped through the slot dye, Allow the cooling fan to pass through to cool quickly on the surface. Cut the net with rounded corners and individual pieces of medicinal 120 mm x 90 mm rectangle size.

Example 170

Representative skin cleansing and conditioning kits are prepared in the following manner.

A skin cleansing article is produced. The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second web of air infused loftable low density bet is continuously injected over the first substrate and placed in contact with the surfactant containing layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Cut the net with individual items of approximately 120 mm x 480 mm rectangular size with rounded corners.

To produce a skin conditioning article. The conditioning composition of Example 34 was applied to four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, measuring 5 mm width and a net width, and each pair of parallel lines on each side of the net So that it is continuously extruded through the coating head and applied to one side of the first substrate. The composition is extruded at a rate such that the composition per finished article is 3 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second net of air infused loftable low density betting is continuously injected over the first substrate and placed in contact with the first substrate on the side not containing the skin conditioning composition. The betting includes a mixture of 35% 3 denier bicomponent fibers having 15 denier PET fibers 30%, PET core and PE sheath and 35 denier bicomponent fibers of the same core-sheet composition, And a basis weight of 100 grams (gsm). The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. The net is cut into individual articles about 120 mm x 160 mm rectangular in size with rounded corners, with a total of about 51 seals per item.

Skin cleansing items and skin conditioning products are packaged together in a single package.

Example 171

Representative skin cleansing and conditioning kits are prepared in the following manner.

A skin cleansing article is produced. The cleansing components of Example 11 were measured by measuring the width across the net and were divided into four lines separated by a distance of 20 mm, 40 mm, and 20 mm, respectively, so that a pair of parallel lines were formed on each side of the net, And applied on one side of the first substrate. The cleansing ingredients are extruded at a rate such that the cleansing component per finished article is 4.4 grams. The substrate is a spunlaced mixture of 70% rayon and 30% PET fibers bonded with a styrene-butadiene adhesive, which is perforated to form pores with a diameter of about 2 mm and a basis weight of about 70 gsm. A second web of air infused loftable low density betting is continuously injected over the first substrate and placed in contact with the surfactant layer. The polyester bets have a basis weight of 2 oz / yd ² and include a fiber mixture of about 23 microns and 40 microns average diameter, with at least some of them wrinkled. The thickness of the betting is about 0.23 in. to be. The betting is believed to be thermally bonded without using an adhesive and has a total scratch cover of about 22%. The mesh is continuously injected with an ultrasonic suturing machine which sutures with a dot pattern containing a grid of uniformly distributed 4 mm diameter suture points across the net. Cut the net with individual items of approximately 120 mm x 480 mm rectangular size with rounded corners.

To produce a skin conditioning article. A substrate is produced which is a hydrated textile mixture of fibers, which has smoother, finer denier fibers on one side and more coarse fibers on the other side. Two substrates each having a basis weight of about 20 gsm and containing 10 denier polyester (PET) fibers are attached to the top of one mesh by air to produce a substrate. A web of polypropylene scrim having a diameter of about 100 microns and woven at intervals of about 0.8 cm is injected over the fibrous web as the third web. A fourth net and a fifth net comprising three denier polyester fibers are each air-bonded to the top of the mesh at about 20 gsm. The net is hydrated and weighed into a single net unit and dried on a dry can until moisture is removed and about 20% reduction due to the relaxation of the scrim occurs. The acrylic adhesive copolymer floating in water at low T _g (about 5 ° C.) is added to the rough fiber side of the web by kiss roll application at a wet addition rate rate of about 7 gsm and dried. The skin conditioning composition of Example 21 was continuously added to the web by uniformly slot coating the composition on both sides of the net at a rate of about 25 gsm per side. The substrate web is cut into individual articles of about 120 mm x 100 mm square in rounded corners, using a high-temperature cutting roll which, when cut, causes the scrim fibers to slightly contract from the edges of the article.

Skin cleansing items and skin conditioning products are packaged together in a single package.

Example 172

Representative skin cleansing and conditioning products are prepared in the following manner.

A first side is produced. A first layer of a first side is produced with polyester bets having a basis weight of 2 oz / yd ² , comprising a fiber mixture of about 23 microns and 40 microns average diameter, with at least a portion of the fibers wrinkled. The thickness of the betting is about 0.23 in. to be. The betting has an air permeability of about 1270 cfm / ft ² and a foam permeable crystal pressure of about 2.7 cm H ₂ O. The betting is considered to be thermally bonded without the use of adhesives. The bet is cut to 10 square inches. A second layer of a first side of a 10 square inch sheet of microporous 100 mesh formed film is prepared by forming a hydration perforation at high pressure on a drum containing a 100 mesh forming screen (see, for example, U.S. Patent No. 4,629,643 Lt; / RTI &gt; The sheet is placed on the first layer with the protruding perforations facing up. 25 grams of the skin cleansing composition of Example 1 is centered on the first side. The composition is slightly flattened to a shape approximately one-half inch thick and several inches in diameter. A layer of impermeable polyethylene film exhibiting a 10 square inch dimension, similar to the first layer, is placed over the composition. 25 grams of the skin conditioning composition of Example 63 is shaped like the cleansing composition and placed on top of the film at the same xy position as the surfactant. A microporous and macroperformed molded film layer (also disclosed in U.S. Patent No. 4,629,643) is placed so that the protruding side of the macroperforation faces the composition side and the protruding side of the microperforation faces upward. Also cut the layer to 10 square inches. A final layer is produced which is a hydration textile mixture of fibers with smooth, fine denier fibers. Two nets each having a basis weight of about 17 gsm and containing 3 denier polyester (PET) fibers are air-bonded to one top of the other to produce a layer. A mesh of elastomeric scrims comprising fibers about 100 microns in diameter in one direction woven with fibers about 40 microns in diameter in the other direction, woven about 0.1 cm apart, is continuously injected across the fibrous web as a third web do. The mesh is available from Conwed Plastics (Minneapolis, MN). The fourth and fifth nets comprising 3 denier polyester fibers are each air-bonded to the top of the net at about 17 gsm. The net is hydrated and weighed into a single net unit and dried on a drying can until moisture is removed. The net is crushed by net stretching during hydration weaving and drying processes and subsequent relaxation after processing. The slices of the layer are cut to a size of about 10 inches by 10 inches and placed over the top of the other layer. The layers are sutured together using a pressure platen type heat sealing device such as a Sentinel Model 808 heat sealer commercially available from Sencorp (Hyannis, Mass.). The untreated (non-heated) bottom plate shaped to contain the composition is used and heat-sealed using a non-treated (heated) top plate that fits the bottom plate around the circular suture rim. Typical sealing conditions are 300 [deg.] C for a residence time of about 3.5 seconds while supplying a pressure of about 30 psig to the machine, but may vary depending on the suture mechanism used. Keep the items in their original packaging until they are handled and used.

Claims (11)

Disposable personal care article suitable for cleansing and substantially dry, characterized by comprising: a) a water-insoluble substrate comprising: 1) a soft first layer exhibiting a total scratch coverage value of less than about 17%; And 2) a second layer for release, located near the first layer, exhibiting a total scratch cover value of from about 17% to about 70%; And and b) from about 10% to about 1000% by weight of the water-insoluble substrate is a foam-forming surfactant. The article of claim 1, wherein the first layer and / or the second layer comprises fibers selected from the group consisting of natural fibers, synthetic fibers, and combinations thereof. The article of claim 1, wherein the first layer and / or the second layer comprises a material selected from the group consisting of a nonwoven fabric and a woven fabric. The article of claim 3, wherein the nonwoven is selected from a batting, a formed film, a cellulosic nonwoven, and combinations thereof. 2. The article of claim 1, wherein the cleansing component lies between the first layer and the second layer. The article of claim 1, wherein the first layer and the second layer are spot bonded to each other. A method of cleansing skin and hair, comprising the steps of: a) wetting the article of paragraph 1; And b) Contact skin or hair with wetted items. A substantially dry disposable personal care article characterized by comprising: a) a water-insoluble substrate comprising: 1) a soft first layer showing an Average Profilometer Depth Value with an average profile of less than about 8; And 2) a second layer for peeling, located near the first layer, representing a meter depth value with an average profile of from about 8 to about 80; And and b) from about 10% to about 1000% by weight of the water-insoluble substrate is a foam-forming surfactant. A disposable personal care article suitable for conditioning and substantially dry, characterized by comprising: a) a water-insoluble substrate comprising: 1) a soft first layer exhibiting a total scratch cover value of less than about 17%; And 2) a second peelable layer exhibiting a total scratch cover value of from about 17% to about 70%; And and b) from about 10% to about 1000% by weight of the water insoluble substrate, of a therapeutically efficacious agent. A substantially dry disposable personal care article, characterized by comprising: a) a water-insoluble substrate comprising: 1) a soft first layer showing a meter depth value with an average profile of less than about 8; And 2) a second layer for peeling, located near the first layer, representing a meter depth value with an average profile of from about 8 to about 80; And and b) from about 10% to about 1000% by weight of the water insoluble substrate, of a therapeutically efficacious agent. A personal care kit comprising an article of claim 1 and an additional article comprising a substrate and a therapeutically effective ingredient.