JP5568137B2 - 含フッ素カルバマート基を有するアミノ酸アミド誘導体の製造方法、その製造中間体、及びエチレンジアミン誘導体の製造方法 - Google Patents
含フッ素カルバマート基を有するアミノ酸アミド誘導体の製造方法、その製造中間体、及びエチレンジアミン誘導体の製造方法 Download PDFInfo
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- JP5568137B2 JP5568137B2 JP2012534932A JP2012534932A JP5568137B2 JP 5568137 B2 JP5568137 B2 JP 5568137B2 JP 2012534932 A JP2012534932 A JP 2012534932A JP 2012534932 A JP2012534932 A JP 2012534932A JP 5568137 B2 JP5568137 B2 JP 5568137B2
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- 0 *C(*)(C(N)=O)N(*)C(O*)=O Chemical compound *C(*)(C(N)=O)N(*)C(O*)=O 0.000 description 6
- VQGQFZPGICMZIC-ZCFIWIBFSA-N CC(C)[C@@H](C#N)NC(OCC(F)(F)F)=O Chemical compound CC(C)[C@@H](C#N)NC(OCC(F)(F)F)=O VQGQFZPGICMZIC-ZCFIWIBFSA-N 0.000 description 1
- OGBFVYCMSNRCLA-ZCFIWIBFSA-N CC(C)[C@@H](CN)NC(OCC(F)(F)F)=O Chemical compound CC(C)[C@@H](CN)NC(OCC(F)(F)F)=O OGBFVYCMSNRCLA-ZCFIWIBFSA-N 0.000 description 1
- KZSNJWFQEVHDMF-SCSAIBSYSA-N CC(C)[C@H](C(O)=O)N Chemical compound CC(C)[C@H](C(O)=O)N KZSNJWFQEVHDMF-SCSAIBSYSA-N 0.000 description 1
- OUNNJHRACCIFBN-RXMQYKEDSA-N CC(C)[C@H](C(O)=O)NC(OCC(F)(F)F)=O Chemical compound CC(C)[C@H](C(O)=O)NC(OCC(F)(F)F)=O OUNNJHRACCIFBN-RXMQYKEDSA-N 0.000 description 1
- PSMAETJSLKYYAZ-JTQLQIEISA-N COC([C@H](Cc1ccccc1)NC(OCC(F)(F)F)=O)=O Chemical compound COC([C@H](Cc1ccccc1)NC(OCC(F)(F)F)=O)=O PSMAETJSLKYYAZ-JTQLQIEISA-N 0.000 description 1
- SQOYMQISEBCWMT-ZDUSSCGKSA-N Cc(cc1)ccc1C(NC[C@H](CCC1)N1C(OCC(F)(F)F)=O)=O Chemical compound Cc(cc1)ccc1C(NC[C@H](CCC1)N1C(OCC(F)(F)F)=O)=O SQOYMQISEBCWMT-ZDUSSCGKSA-N 0.000 description 1
- WYCCFSISEZQSML-LURJTMIESA-N NC[C@H](CCC1)N1C(OCC(F)(F)F)=O Chemical compound NC[C@H](CCC1)N1C(OCC(F)(F)F)=O WYCCFSISEZQSML-LURJTMIESA-N 0.000 description 1
- UJZBSAONPRVEIJ-UHFFFAOYSA-N O=C(OCC(F)(F)F)Cl Chemical compound O=C(OCC(F)(F)F)Cl UJZBSAONPRVEIJ-UHFFFAOYSA-N 0.000 description 1
- OCSLJTBVIIHOEU-VIFPVBQESA-N O=C([C@H](Cc1ccccc1)NC(OCC(F)(F)F)=O)Cl Chemical compound O=C([C@H](Cc1ccccc1)NC(OCC(F)(F)F)=O)Cl OCSLJTBVIIHOEU-VIFPVBQESA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012534932A JP5568137B2 (ja) | 2010-09-22 | 2011-09-21 | 含フッ素カルバマート基を有するアミノ酸アミド誘導体の製造方法、その製造中間体、及びエチレンジアミン誘導体の製造方法 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010212143 | 2010-09-22 | ||
| JP2010212143 | 2010-09-22 | ||
| JP2012534932A JP5568137B2 (ja) | 2010-09-22 | 2011-09-21 | 含フッ素カルバマート基を有するアミノ酸アミド誘導体の製造方法、その製造中間体、及びエチレンジアミン誘導体の製造方法 |
| PCT/JP2011/005307 WO2012039132A1 (fr) | 2010-09-22 | 2011-09-21 | Procédé de production de dérivé d'amide d'acide aminé pourvu d'un groupe carbamate contenant du fluor, intermédiaire de production de ce dérivé et procédé de production de dérivé d'éthylène-diamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2012039132A1 JPWO2012039132A1 (ja) | 2014-02-03 |
| JP5568137B2 true JP5568137B2 (ja) | 2014-08-06 |
Family
ID=45873631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534932A Active JP5568137B2 (ja) | 2010-09-22 | 2011-09-21 | 含フッ素カルバマート基を有するアミノ酸アミド誘導体の製造方法、その製造中間体、及びエチレンジアミン誘導体の製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP5568137B2 (fr) |
| KR (1) | KR101492351B1 (fr) |
| CN (1) | CN103124722B (fr) |
| WO (1) | WO2012039132A1 (fr) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60224648A (ja) * | 1984-03-29 | 1985-11-09 | チバ‐ガイギー アーゲー | 部分ハロゲン化α‐置換１‐プロパノール、その製法並びにそのクロロホルメートおよびその用途 |
| JPS6310759A (ja) * | 1985-11-14 | 1988-01-18 | ワ−ナ−−ランバ−ト・コンパニ− | ２−置換−〔２−置換−アミノ〕−ｎ−アリ−ルアルキル−３−〔インド−ル−３−イル〕プロパンアミド |
| JPH11158157A (ja) * | 1997-09-18 | 1999-06-15 | Hoechst Marion Roussel Deutsche Gmbh | 新規なイミダゾリジン誘導体、その製造およびその使用ならびにそれを含有する医薬製剤 |
| WO2007111024A1 (fr) * | 2006-03-29 | 2007-10-04 | Mitsui Chemicals, Inc. | Procede de production d'un derive d'ethylenediamine ayant un groupement carbamate halogene et un groupement acyle, et intermediaire de production du derive |
| WO2009005677A2 (fr) * | 2007-06-29 | 2009-01-08 | Gilead Sciences, Inc. | Composés antiviraux |
| JP2010510234A (ja) * | 2006-11-16 | 2010-04-02 | ブリストル−マイヤーズ スクイブ カンパニー | Ｃ型肝炎ウイルス阻害剤としての大環状ペプチド |
| JP2010527373A (ja) * | 2007-05-17 | 2010-08-12 | ブリストル−マイヤーズ スクイブ カンパニー | Ｃ型肝炎ウイルス阻害剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4757151A (en) * | 1985-11-14 | 1988-07-12 | Warner-Lambert Company | 2-substituted-[2-substituted-amino]-N-arylalkyl-3-[indol-3-yl] |
| WO2003008372A1 (fr) * | 2001-07-18 | 2003-01-30 | Mitsui Chemicals, Inc. | Derive de diamine, processus de production de ce compose et bactericide contenant ce compose comme principe actif |
| JP3803622B2 (ja) * | 2001-07-18 | 2006-08-02 | 三井化学株式会社 | ジアミン誘導体、その製造方法およびそれらを有効成分とする殺菌剤 |
| EP1681285A4 (fr) * | 2003-10-31 | 2006-11-22 | Mitsui Chemicals Inc | Derives de diamine et leur procede de production, et agent de lutte contre les maladies des plantes contenant lesdits derives comme ingredient actif |
| JP4533210B2 (ja) * | 2005-03-31 | 2010-09-01 | 三井化学アグロ株式会社 | ジアミン誘導体、その製造方法およびそれらを有効成分とする植物病害防除剤 |
| CN101652383B (zh) * | 2006-11-16 | 2013-09-18 | 百时美施贵宝公司 | 丙型肝炎病毒抑制剂 |
-
2011
- 2011-09-21 JP JP2012534932A patent/JP5568137B2/ja active Active
- 2011-09-21 CN CN201180044958.5A patent/CN103124722B/zh active Active
- 2011-09-21 KR KR1020137008216A patent/KR101492351B1/ko active Active
- 2011-09-21 WO PCT/JP2011/005307 patent/WO2012039132A1/fr not_active Ceased
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60224648A (ja) * | 1984-03-29 | 1985-11-09 | チバ‐ガイギー アーゲー | 部分ハロゲン化α‐置換１‐プロパノール、その製法並びにそのクロロホルメートおよびその用途 |
| JPS6310759A (ja) * | 1985-11-14 | 1988-01-18 | ワ−ナ−−ランバ−ト・コンパニ− | ２−置換−〔２−置換−アミノ〕−ｎ−アリ−ルアルキル−３−〔インド−ル−３−イル〕プロパンアミド |
| JPH11158157A (ja) * | 1997-09-18 | 1999-06-15 | Hoechst Marion Roussel Deutsche Gmbh | 新規なイミダゾリジン誘導体、その製造およびその使用ならびにそれを含有する医薬製剤 |
| WO2007111024A1 (fr) * | 2006-03-29 | 2007-10-04 | Mitsui Chemicals, Inc. | Procede de production d'un derive d'ethylenediamine ayant un groupement carbamate halogene et un groupement acyle, et intermediaire de production du derive |
| JP2010510234A (ja) * | 2006-11-16 | 2010-04-02 | ブリストル−マイヤーズ スクイブ カンパニー | Ｃ型肝炎ウイルス阻害剤としての大環状ペプチド |
| JP2010527373A (ja) * | 2007-05-17 | 2010-08-12 | ブリストル−マイヤーズ スクイブ カンパニー | Ｃ型肝炎ウイルス阻害剤 |
| WO2009005677A2 (fr) * | 2007-06-29 | 2009-01-08 | Gilead Sciences, Inc. | Composés antiviraux |
Non-Patent Citations (2)
| Title |
|---|
| JPN6014012580; ＪＯＵＲＮＡＬ ＯＦ ＯＬＥＯ ＳＣＩＥＮＣＥ Ｖ５９, 20100318, Ｎ１９１-２０１ * |
| JPN6014012583; Ｊ． ＭＥＤ． ＣＨＥＭ Ｖ４０, 1997, Ｐ２０６４-２０８４ * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103124722B (zh) | 2014-11-12 |
| WO2012039132A1 (fr) | 2012-03-29 |
| KR101492351B1 (ko) | 2015-02-10 |
| KR20130069781A (ko) | 2013-06-26 |
| JPWO2012039132A1 (ja) | 2014-02-03 |
| CN103124722A (zh) | 2013-05-29 |
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