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JP5236627B2 - 不斉四置換キノロンカルボン酸の製造方法およびその製造中間体 - Google Patents

不斉四置換キノロンカルボン酸の製造方法およびその製造中間体 Download PDF

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Publication number
JP5236627B2
JP5236627B2 JP2009506331A JP2009506331A JP5236627B2 JP 5236627 B2 JP5236627 B2 JP 5236627B2 JP 2009506331 A JP2009506331 A JP 2009506331A JP 2009506331 A JP2009506331 A JP 2009506331A JP 5236627 B2 JP5236627 B2 JP 5236627B2
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Japan
Prior art keywords
carbon atoms
group
compound
formula
substituent
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Expired - Fee Related
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JP2009506331A
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English (en)
Japanese (ja)
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JPWO2008117773A1 (ja
Inventor
耕司 佐藤
努 八木
裕一 小平
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Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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Priority to JP2009506331A priority Critical patent/JP5236627B2/ja
Publication of JPWO2008117773A1 publication Critical patent/JPWO2008117773A1/ja
Application granted granted Critical
Publication of JP5236627B2 publication Critical patent/JP5236627B2/ja
Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/31—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP2009506331A 2007-03-26 2008-03-24 不斉四置換キノロンカルボン酸の製造方法およびその製造中間体 Expired - Fee Related JP5236627B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009506331A JP5236627B2 (ja) 2007-03-26 2008-03-24 不斉四置換キノロンカルボン酸の製造方法およびその製造中間体

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007078651 2007-03-26
JP2007078651 2007-03-26
JP2009506331A JP5236627B2 (ja) 2007-03-26 2008-03-24 不斉四置換キノロンカルボン酸の製造方法およびその製造中間体
PCT/JP2008/055424 WO2008117773A1 (fr) 2007-03-26 2008-03-24 Procédé de production d'acides quinolonecarboxyliques tétrasubstitués asymétriques et intermédiaires pour la production

Publications (2)

Publication Number Publication Date
JPWO2008117773A1 JPWO2008117773A1 (ja) 2010-07-15
JP5236627B2 true JP5236627B2 (ja) 2013-07-17

Family

ID=39788508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009506331A Expired - Fee Related JP5236627B2 (ja) 2007-03-26 2008-03-24 不斉四置換キノロンカルボン酸の製造方法およびその製造中間体

Country Status (3)

Country Link
JP (1) JP5236627B2 (fr)
TW (1) TW200846336A (fr)
WO (1) WO2008117773A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09208561A (ja) * 1995-05-26 1997-08-12 Dai Ichi Seiyaku Co Ltd 環式化合物の製法
JP2003306475A (ja) * 2002-02-13 2003-10-28 Dai Ichi Seiyaku Co Ltd 光学活性化合物の製法
WO2006123767A1 (fr) * 2005-05-20 2006-11-23 Daiichi Sankyo Company, Limited Procede de production d’un compose contenant un atome de carbone asymetrique tetrasubstitue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09208561A (ja) * 1995-05-26 1997-08-12 Dai Ichi Seiyaku Co Ltd 環式化合物の製法
JP2003306475A (ja) * 2002-02-13 2003-10-28 Dai Ichi Seiyaku Co Ltd 光学活性化合物の製法
WO2006123767A1 (fr) * 2005-05-20 2006-11-23 Daiichi Sankyo Company, Limited Procede de production d’un compose contenant un atome de carbone asymetrique tetrasubstitue

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6013013721; ＭＯＳＳ，　Ｎ．: 'Ａｎ　ｅｎａｎｔｉｏｓｅｌｅｃｔｉｖｅ　ｓｙｎｔｈｅｓｉｓ　ｏｆ　ｃｙｃｌｏｐｅｎｔｙｌ-Ｌ-ａｓｐａｒｔｉｃ　ａｃｉｄａｍｅｎａｂｌｅ　ｔｏ　ｌａｒｇｅ　ｓｃａｌｅ' Ｓｙｎｔｈｅｓｉｓ Ｎｏ．１, 1997, ｐ．３２-３４ *
JPN6013013722; ＭＡＣＤＯＮＡＬＤ，　Ｓ．　Ｊ．: 'Ａ　Ｆｌｅｘｉｂｌｅ，　Ｐｒａｃｔｉｃａｌ，　ａｎｄ　Ｓｔｅｒｅｏｓｅｌｅｃｔｉｖｅ　Ｓｙｎｔｈｅｓｉｓ　ｏｆＥｎａｎｔｉｏｍｅｒｉｃａｌｌｙ　Ｐｕｒｅ　ｔｒａｎｓ-５-Ｏｘｏｈｅｘａｈｙｄｒｏｐｙｒ' Ｊｏｕｒｎａｌｏｆ　Ｏｒｇａｎｉｃ　Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．６４，　Ｎｏ．１４, 1999, ｐ．５１６６-５１７５ *

Also Published As

Publication number Publication date
WO2008117773A1 (fr) 2008-10-02
TW200846336A (en) 2008-12-01
JPWO2008117773A1 (ja) 2010-07-15

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