IT1313550B1 - Composizione a base di un pre-concentrato di emulsione che comprendeuna sostanza attiva difficilmente solubile ed un mezzo-veicolo - Google Patents

Composizione a base di un pre-concentrato di emulsione che comprendeuna sostanza attiva difficilmente solubile ed un mezzo-veicolo

Info

Publication number: IT1313550B1
Authority: IT; Italy
Prior art keywords: concentrate; emulsion; vehicle; active substance; composition based
Prior art date: 1998-03-06

Application number

IT1999MI000452A

Other languages

English (en)

Inventor

Michael Ambuehl

Barbara Lueckel

Friedrich Richter

Barbara Haeberlin

Armin Meinzer

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-06

Filing date

1999-03-05

Publication date

2002-09-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269231&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1313550(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-03-06 Priority claimed from GBGB9804742.6A external-priority patent/GB9804742D0/en

1998-03-10 Priority claimed from GBGB9805104.8A external-priority patent/GB9805104D0/en

1998-03-11 Priority claimed from GBGB9805199.8A external-priority patent/GB9805199D0/en

1999-03-05 Application filed by Novartis Ag filed Critical Novartis Ag

2000-09-05 Publication of ITMI990452A1 publication Critical patent/ITMI990452A1/it

2002-09-09 Application granted granted Critical

2002-09-09 Publication of IT1313550B1 publication Critical patent/IT1313550B1/it

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Dispersion Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Transplantation (AREA)
Biophysics (AREA)
Rheumatology (AREA)
Molecular Biology (AREA)
Surgery (AREA)
Communicable Diseases (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT1999MI000452A 1998-03-06 1999-03-05 Composizione a base di un pre-concentrato di emulsione che comprendeuna sostanza attiva difficilmente solubile ed un mezzo-veicolo IT1313550B1 (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9804742.6A GB9804742D0 (en)	1998-03-06	1998-03-06	Organic compounds
GBGB9805104.8A GB9805104D0 (en)	1998-03-10	1998-03-10	Organic compounds
GBGB9805199.8A GB9805199D0 (en)	1998-03-11	1998-03-11	Organic compounds

Publications (2)

Publication Number	Publication Date
ITMI990452A1 ITMI990452A1 (it)	2000-09-05
IT1313550B1 true IT1313550B1 (it)	2002-09-09

Family

ID=27269231

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT1999MI000452A IT1313550B1 (it)	1998-03-06	1999-03-05	Composizione a base di un pre-concentrato di emulsione che comprendeuna sostanza attiva difficilmente solubile ed un mezzo-veicolo

Country Status (29)

Country	Link
EP (2)	EP1354582A3 (it)
JP (2)	JP2002505271A (it)
KR (1)	KR100443306B1 (it)
CN (1)	CN1195495C (it)
AR (1)	AR015729A1 (it)
AT (1)	ATE277599T1 (it)
AU (1)	AU749217B2 (it)
BE (3)	BE1012400A5 (it)
BR (1)	BR9908597A (it)
CA (1)	CA2322845C (it)
CO (1)	CO4930289A1 (it)
CZ (1)	CZ301967B6 (it)
DE (2)	DE19983012T1 (it)
ES (1)	ES2228014T3 (it)
FR (4)	FR2775596B1 (it)
GB (1)	GB2350791B (it)
HU (1)	HUP0101080A3 (it)
ID (1)	ID25908A (it)
IL (2)	IL138248A0 (it)
IT (1)	IT1313550B1 (it)
MY (1)	MY129274A (it)
NO (1)	NO331800B1 (it)
NZ (1)	NZ506644A (it)
PE (1)	PE20000324A1 (it)
PT (1)	PT1059913E (it)
SK (1)	SK285139B6 (it)
TR (1)	TR200002586T2 (it)
TW (3)	TWI257870B (it)
WO (1)	WO1999044584A1 (it)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5858401A (en)	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
JP2002531515A (ja) *	1998-12-11	2002-09-24	ファーマソリューションズ・インコーポレイテッド	水に難溶性の薬剤のための自己乳化組成物
DK1154759T3 (da) *	1998-12-30	2008-12-08	Dexcel Ltd	Dispergerbart koncentrat til indgift af cyclosporin
US6294192B1 (en) *	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20070032853A1 (en)	2002-03-27	2007-02-08	Hossainy Syed F	40-O-(2-hydroxy)ethyl-rapamycin coated stent
AU2127400A (en) *	1999-11-02	2001-05-14	Cipla Limited	A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof
GB2362573A (en) *	2000-05-25	2001-11-28	Cipla Ltd	Cyclosporin formulation
AU1043201A (en) *	1999-11-02	2001-05-14	Cipla Limited	Cyclosporin formulation
GB0008785D0 (en) *	2000-04-10	2000-05-31	Novartis Ag	Organic compounds
DE10024451A1 (de) *	2000-05-18	2001-11-29	Asta Medica Ag	Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
WO2003002095A1 (fr) *	2001-06-28	2003-01-09	Chugai Seiyaku Kabushiki Kaisha	Preparation d'une micro-emulsion de type huile-eau
US6960563B2 (en)	2001-08-31	2005-11-01	Morton Grove Pharmaceuticals, Inc.	Spontaneous emulsions containing cyclosporine
GB2391471B (en) *	2002-08-02	2005-05-04	Satishchandra Punambhai Patel	Pharmaceutical compositions
KR20040047056A (ko) *	2002-11-29	2004-06-05	한미약품 주식회사	비페닐디메틸디카복실레이트의 경구용 마이크로에멀젼조성물
US8802116B2 (en)	2003-02-27	2014-08-12	Novasel Australia Pty. Ltd.	Poloxamer emulsion preparations
KR20040084240A (ko) *	2003-03-27	2004-10-06	(주) 코스메디	고형지질나노입자, 이를 함유하는 활성성분 전달용약학조성물 및 이의 제조방법
US20050118344A1 (en)	2003-12-01	2005-06-02	Pacetti Stephen D.	Temperature controlled crimping
JP2008518931A (ja) *	2004-10-29	2008-06-05	ノバルティスアクチエンゲゼルシャフト	自発的に分散可能な医薬組成物
MX2007011250A (es) *	2005-03-21	2007-11-14	Ivax Pharmaceuticals Sro	Inhibidor de la cristalizacion y su uso en capsulas de gelatina.
CN101032620B (zh) *	2007-03-08	2010-05-19	上海凯昭医药科技有限公司	一种环孢素自乳化制剂及其制备方法
US20090130198A1 (en) *	2007-11-21	2009-05-21	Innopharmax Inc.	Pharmaceutical composition with enhanced bioavailability
AU2009226019C1 (en)	2008-03-20	2014-02-20	Virun, Inc.	Emulsions including a PEG-derivative of tocopherol
CN102036661B (zh)	2008-03-20	2016-12-28	维尔恩公司	维生素衍生物及其用途
US11304960B2 (en)	2009-01-08	2022-04-19	Chandrashekar Giliyar	Steroidal compositions
JP5567909B2 (ja) *	2010-06-17	2014-08-06	東洋カプセル株式会社	タクロリムス含有カプセル剤
US8741373B2 (en)	2010-06-21	2014-06-03	Virun, Inc.	Compositions containing non-polar compounds
US20180153904A1 (en)	2010-11-30	2018-06-07	Lipocine Inc.	High-strength testosterone undecanoate compositions
US9034858B2 (en)	2010-11-30	2015-05-19	Lipocine Inc.	High-strength testosterone undecanoate compositions
US9358241B2 (en)	2010-11-30	2016-06-07	Lipocine Inc.	High-strength testosterone undecanoate compositions
US20120148675A1 (en)	2010-12-10	2012-06-14	Basawaraj Chickmath	Testosterone undecanoate compositions
JO3337B1 (ar)	2010-12-13	2019-03-13	Debiopharm Sa	تركيبات صيدلية تشمل أليسبوريفير
JP5717034B2 (ja) *	2012-08-27	2015-05-13	丸和バイオケミカル株式会社	マクロライド系化合物を含有する土壌線虫防除用薬剤
US20150374835A1 (en)	2012-12-31	2015-12-31	Jrx Biotechnology, Inc.	Liquid topical pharmaceutical nano-emulsion formulations
KR101458466B1 (ko) *	2013-06-24	2014-11-07	한국화학연구원	면역억제제가 봉입된 마이셀을 함유하는 경구제
WO2016033556A1 (en)	2014-08-28	2016-03-03	Lipocine Inc.	BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
US20170246187A1 (en)	2014-08-28	2017-08-31	Lipocine Inc.	(17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20160361322A1 (en)	2015-06-15	2016-12-15	Lipocine Inc.	Composition and method for oral delivery of androgen prodrugs
CN108024914A (zh)	2015-09-17	2018-05-11	Jrx生物技术有限公司	改善皮肤的水合作用或润湿作用的方法
WO2018098501A1 (en)	2016-11-28	2018-05-31	Lipocine Inc.	Oral testosterone undecanoate therapy
WO2020018974A1 (en)	2018-07-20	2020-01-23	Lipocine Inc.	Liver disease
SI3886813T1 (sl) *	2018-11-26	2023-05-31	Hepion Pharmaceuticals, Inc.	Farmacevtske formulacije analogov ciklosporina
WO2024014958A2 (en) *	2022-07-15	2024-01-18	Seranovo Holding B.V.	Lides formulation platform
WO2024014959A2 (en) *	2022-07-15	2024-01-18	Seranovo Holding B.V.	Micelle-generating formulations with improved hydrophobicity
CN117797093A (zh) *	2024-02-29	2024-04-02	中国农业科学院农业环境与可持续发展研究所	一种以大环内酯类药物为活性成分的兽用口服纳米液体制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8903804D0 (en) *	1989-02-20	1989-04-05	Sandoz Ltd	Improvements in or relating to organic compounds
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
JP2632010B2 (ja) *	1988-01-29	1997-07-16	三共株式会社	シクロスポリン製剤
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds
EP1142568A1 (en) *	1992-09-25	2001-10-10	Novartis AG	Pharmaceutical compositions containing cyclosporins
GB2278780B (en) *	1993-05-27	1998-10-14	Sandoz Ltd	Macrolide formulations
DE4322826A1 (de) *	1993-07-08	1995-01-12	Galenik Labor Freiburg Gmbh	Pharmazeutisches Präparat
WO1995022343A1 (en) *	1994-02-17	1995-08-24	Shiseido Company, Ltd.	Cyclosporin-containing emulsion composition
JP3131112B2 (ja) *	1994-02-17	2001-01-31	株式会社資生堂	シクロスポリン含有乳化組成物
DK0786986T3 (da) *	1994-10-26	2002-04-29	Novartis Ag	Anvendelse af en umættet fedtalkohol
IL129547A (en) *	1994-10-26	2001-01-11	Novartis Ag	Pharmaceutical compositions comprising a macrolide and an acid
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
KR970064620A (ko) *	1996-03-05	1997-10-13	임성기	사이클로스포린-함유 외용약제 조성물
KR980008239A (ko) *	1996-07-26	1998-04-30	김충환	사이클로스포린-함유 약학적 조성물
US6063762A (en) *	1997-12-05	2000-05-16	Chong Kun Dang Corp.	Cyclosporin-containing microemulsion preconcentrate composition
DE69842121D1 (de) *	1997-12-10	2011-03-17	Cyclosporine Therapeutics Ltd	Omega-3 fettsäure enthaltende pharmazeutische zusammensetzungen

1998
- 1998-10-16 ID IDW20001708A patent/ID25908A/id unknown
1999
- 1999-03-04 FR FR9902748A patent/FR2775596B1/fr not_active Expired - Fee Related
- 1999-03-04 HU HU0101080A patent/HUP0101080A3/hu unknown
- 1999-03-04 EP EP03013016A patent/EP1354582A3/en not_active Withdrawn
- 1999-03-04 DE DE19983012T patent/DE19983012T1/de not_active Withdrawn
- 1999-03-04 CA CA002322845A patent/CA2322845C/en not_active Expired - Fee Related
- 1999-03-04 CZ CZ20003222A patent/CZ301967B6/cs not_active IP Right Cessation
- 1999-03-04 BR BR9908597-6A patent/BR9908597A/pt not_active IP Right Cessation
- 1999-03-04 IL IL13824899A patent/IL138248A0/xx active IP Right Grant
- 1999-03-04 PE PE1999000178A patent/PE20000324A1/es not_active Application Discontinuation
- 1999-03-04 GB GB0021495A patent/GB2350791B/en not_active Expired - Fee Related
- 1999-03-04 WO PCT/EP1999/001415 patent/WO1999044584A1/en not_active Ceased
- 1999-03-04 SK SK1319-2000A patent/SK285139B6/sk not_active IP Right Cessation
- 1999-03-04 AT AT99908952T patent/ATE277599T1/de active
- 1999-03-04 AR ARP990100910A patent/AR015729A1/es not_active Application Discontinuation
- 1999-03-04 CN CNB99803746XA patent/CN1195495C/zh not_active Expired - Fee Related
- 1999-03-04 JP JP2000534187A patent/JP2002505271A/ja not_active Withdrawn
- 1999-03-04 EP EP99908952A patent/EP1059913B1/en not_active Revoked
- 1999-03-04 PT PT99908952T patent/PT1059913E/pt unknown
- 1999-03-04 ES ES99908952T patent/ES2228014T3/es not_active Expired - Lifetime
- 1999-03-04 BE BE9900153A patent/BE1012400A5/fr not_active IP Right Cessation
- 1999-03-04 DE DE69920668T patent/DE69920668T2/de not_active Expired - Lifetime
- 1999-03-04 KR KR10-2000-7009861A patent/KR100443306B1/ko not_active Expired - Fee Related
- 1999-03-04 NZ NZ506644A patent/NZ506644A/xx not_active IP Right Cessation
- 1999-03-04 TR TR2000/02586T patent/TR200002586T2/xx unknown
- 1999-03-04 AU AU28361/99A patent/AU749217B2/en not_active Ceased
- 1999-03-05 CO CO99013726A patent/CO4930289A1/es unknown
- 1999-03-05 MY MYPI99000807A patent/MY129274A/en unknown
- 1999-03-05 IT IT1999MI000452A patent/IT1313550B1/it active
- 1999-05-21 TW TW094129536A patent/TWI257870B/zh not_active IP Right Cessation
- 1999-05-21 TW TW093120909A patent/TWI248368B/zh not_active IP Right Cessation
- 1999-05-21 TW TW088107417A patent/TWI236912B/zh not_active IP Right Cessation
- 1999-11-09 BE BE9900732A patent/BE1013423A5/fr not_active IP Right Cessation
2000
- 2000-08-18 BE BE2000/0520A patent/BE1013648A5/fr not_active IP Right Cessation
- 2000-08-29 NO NO20004299A patent/NO331800B1/no not_active IP Right Cessation
- 2000-09-05 IL IL138248A patent/IL138248A/en not_active IP Right Cessation
- 2000-10-25 FR FR0013782A patent/FR2800277B1/fr not_active Expired - Fee Related
2004
- 2004-03-05 JP JP2004062679A patent/JP2004189753A/ja active Pending
- 2004-03-26 FR FR0403163A patent/FR2853546B1/fr not_active Expired - Fee Related
2006
- 2006-01-05 FR FR0600097A patent/FR2881956A1/fr not_active Withdrawn

Also Published As

Publication number	Publication date
TWI257870B (en)	2006-07-11
WO1999044584A1 (en)	1999-09-10
NZ506644A (en)	2004-02-27
ITMI990452A1 (it)	2000-09-05
CN1292684A (zh)	2001-04-25
EP1059913A1 (en)	2000-12-20
CO4930289A1 (es)	2000-06-27
AR015729A1 (es)	2001-05-16
HUP0101080A2 (hu)	2001-08-28
TWI236912B (en)	2005-08-01
SK285139B6 (sk)	2006-07-07
BE1013423A5 (fr)	2002-01-15
IL138248A (en)	2006-06-11
EP1354582A2 (en)	2003-10-22
DE69920668D1 (de)	2004-11-04
DE69920668T2 (de)	2005-10-06
DE19983012T1 (de)	2001-02-01
SK13192000A3 (sk)	2001-02-12
GB0021495D0 (en)	2000-10-18
EP1059913B1 (en)	2004-09-29
TR200002586T2 (tr)	2000-11-21
ES2228014T3 (es)	2005-04-01
NO331800B1 (no)	2012-04-02
CZ20003222A3 (cs)	2000-12-13
GB2350791A (en)	2000-12-13
CZ301967B6 (cs)	2010-08-18
KR100443306B1 (ko)	2004-08-09
NO20004299L (no)	2000-08-29
ATE277599T1 (de)	2004-10-15
HK1034038A1 (en)	2001-10-12
ID25908A (id)	2000-11-09
HK1033277A1 (en)	2001-08-24
FR2853546B1 (fr)	2006-04-07
FR2853546A1 (fr)	2004-10-15
IL138248A0 (en)	2001-10-31
BE1013648A5 (fr)	2002-05-07
PT1059913E (pt)	2005-01-31
MY129274A (en)	2007-03-30
FR2800277A1 (fr)	2001-05-04
CA2322845A1 (en)	1999-09-10
FR2800277B1 (fr)	2004-06-25
HUP0101080A3 (en)	2001-12-28
FR2775596B1 (fr)	2004-12-24
FR2775596A1 (fr)	1999-09-10
PE20000324A1 (es)	2000-04-13
TW200422057A (en)	2004-11-01
JP2004189753A (ja)	2004-07-08
AU749217B2 (en)	2002-06-20
AU2836199A (en)	1999-09-20
KR20010041657A (ko)	2001-05-25
CN1195495C (zh)	2005-04-06
BE1012400A5 (fr)	2000-10-03
BR9908597A (pt)	2000-11-14
JP2002505271A (ja)	2002-02-19
CA2322845C (en)	2009-12-08
EP1354582A3 (en)	2004-06-09
GB2350791B (en)	2003-04-02
TWI248368B (en)	2006-02-01
NO20004299D0 (no)	2000-08-29
FR2881956A1 (fr)	2006-08-18

Publication	Publication Date	Title
IT1313550B1 (it)	2002-09-09	Composizione a base di un pre-concentrato di emulsione che comprendeuna sostanza attiva difficilmente solubile ed un mezzo-veicolo
NO992340D0 (no)	1999-05-14	Faste farmas°ytiske blandinger omfattende et cyklosporin og et aniomisk overflateaktivt middel
NZ280610A (en)	1997-08-22	Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
FI960032L (fi)	1996-02-09	Farmaseuttisia koostumuksia vaikeasti liukenevia aktiiviaineita varten
EP0684044A3 (en)	1996-03-06	A composition containing dendrimer and active ingredient.
FI955042A7 (fi)	1995-11-29	Syklosporiinia sisältävä jauhemainen koostumus
DE69832359D1 (de)	2005-12-22	Halbleitervorrichtung -anordnung und -schaltungen
NO20012915L (no)	2001-08-13	Ny farmasöytisk formulering
CY1108180T1 (el)	2014-02-12	Προληπτικα ή/και θεραπευτικα για συστημικο ερυθηματωδη λυκο που περιεχουν αντισωμα αντι-il-6 υποδοχεα ως το δραστικο συστατικο
ID25533A (id)	2000-10-12	Formulasi 2-metil-tieno-benzodiazepin
DE69806914D1 (de)	2002-09-05	Agentimplementierte verriegelungsvorrichtung
FR2760970B1 (fr)	2000-03-10	Nanoemulsions a base de lipides amphiphiles non-ioniques et de silicones aminees et utilisations
FI973320A7 (fi)	1997-10-13	Kiinteitä aktiiviainetta sisältäviä valmisteita
ZA991408B (en)	1999-08-23	Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
DE69835650D1 (de)	2006-10-05	Magnetische Tunnelübergangsvorrichtungen
NO20000464D0 (no)	2000-01-28	Acykliske metalloprotease-inhibitorer
DK1073417T3 (da)	2003-03-24	Farmaceutisk aerosolformulering
DE69815842T2 (de)	2004-01-15	Riechstofffixiermittel die polyvinylpyrrolidon und hydroxylcellulose enthalten
NL1002280A1 (nl)	1996-08-22	Verbeterde verbindingsklem met wiggen voor geïntegreerde schakelingen.
PT1378166E (pt)	2005-02-28	Formulacoes pesticidas contendo tensioactivo ester de fosfato e lenho-sulfonato alcoxilado
IT1302019B1 (it)	2000-07-20	Miscela stabilizzante sinergica a base di polialchil-1-ossa-diazaspirodecani.
NO993694L (no)	1999-07-29	Sylfonylurea- og adjuvansbaserte faste blandinger
IT1304190B1 (it)	2001-03-08	Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche
FR2773067B1 (fr)	2000-03-03	Composition cosmetique de vernis a base de nitrocellulose contenant un agent stabilisant
EE9800275A (et)	1999-02-15	Misolastiini sisaldavad prolongeeritud toimega farmatseutilised preparaadid