IS7006A - Tvívetnis 3-piperidínóprópíófenon og lyf sem innihalda téð efnasambönd - Google Patents
Tvívetnis 3-piperidínóprópíófenon og lyf sem innihalda téð efnasamböndInfo
- Publication number
- IS7006A IS7006A IS7006A IS7006A IS7006A IS 7006 A IS7006 A IS 7006A IS 7006 A IS7006 A IS 7006A IS 7006 A IS7006 A IS 7006A IS 7006 A IS7006 A IS 7006A
- Authority
- IS
- Iceland
- Prior art keywords
- piperidinopropiophenone
- dihydrogen
- compounds
- products containing
- piperidinopropiophenones
- Prior art date
Links
- BIBARRYXKABQKJ-UHFFFAOYSA-N 1-phenyl-3-piperidin-1-ylpropan-1-one Chemical compound C=1C=CC=CC=1C(=O)CCN1CCCCC1 BIBARRYXKABQKJ-UHFFFAOYSA-N 0.000 title abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 230000003387 muscular Effects 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123129A DE10123129A1 (de) | 2001-05-02 | 2001-05-02 | Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel |
| PCT/DE2002/001607 WO2002088100A2 (de) | 2001-05-02 | 2002-04-29 | Deuterierte 3-piperidinopropiophenone sowie diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7006A true IS7006A (is) | 2003-10-30 |
Family
ID=7684543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7006A IS7006A (is) | 2001-05-02 | 2003-10-30 | Tvívetnis 3-piperidínóprópíófenon og lyf sem innihalda téð efnasambönd |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7307091B2 (is) |
| EP (1) | EP1383752B1 (is) |
| JP (1) | JP4373097B2 (is) |
| KR (1) | KR100894846B1 (is) |
| CN (2) | CN1293064C (is) |
| AT (1) | ATE298324T1 (is) |
| AU (1) | AU2002257562B2 (is) |
| CA (1) | CA2446890C (is) |
| CZ (1) | CZ20033060A3 (is) |
| DE (2) | DE10123129A1 (is) |
| DK (1) | DK1383752T3 (is) |
| ES (1) | ES2244768T3 (is) |
| HU (1) | HUP0400077A2 (is) |
| IL (1) | IL158668A0 (is) |
| IS (1) | IS7006A (is) |
| NO (1) | NO20034863L (is) |
| NZ (1) | NZ529586A (is) |
| PL (1) | PL363313A1 (is) |
| PT (1) | PT1383752E (is) |
| RU (1) | RU2296755C2 (is) |
| SI (1) | SI1383752T1 (is) |
| WO (1) | WO2002088100A2 (is) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10261807A1 (de) * | 2002-12-19 | 2004-07-01 | Turicum Drug Development Ag | Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel |
| HUP0300929A3 (en) * | 2003-04-09 | 2005-06-28 | Richter Gedeon Vegyeszet | Analgetic and/or muscle relaxant pharmaceutical composition |
| DE102005014080B4 (de) * | 2005-03-21 | 2007-11-22 | Birds Pharma Gmbh Berolina Innovative Research & Development Services | Additionssalze des Tolperison, Verfahren zu deren Herstellung, Verwendung derselben und diese enthaltende Arzneimittel |
| AR054584A1 (es) * | 2005-07-26 | 2007-06-27 | Altana Pharma Ag | Inhibidores de la bomba de protones isotopicamente sustituidos |
| US7601737B2 (en) * | 2005-07-26 | 2009-10-13 | Nycomed Gmbh | Isotopically substituted proton pump inhibitors |
| CN101268050B (zh) * | 2005-07-26 | 2012-11-28 | 奈科明有限责任公司 | 同位素取代的泮托拉唑 |
| CN101309917B (zh) * | 2005-10-06 | 2013-09-11 | 奥斯拜客斯制药有限公司 | 具有增强治疗性质的胃h+，k+-atp酶氘代抑制剂 |
| US8604031B2 (en) | 2006-05-18 | 2013-12-10 | Mannkind Corporation | Intracellular kinase inhibitors |
| EP2049117A4 (en) * | 2006-08-08 | 2010-08-25 | Auspex Pharmaceuticals Inc | PREPARATION AND USE OF SUBSTITUTED CHINAZOLIN COMPOUNDS WITH ALPHA-ADRENERGER BLOKING EFFECT |
| EP2611759A1 (en) * | 2010-09-03 | 2013-07-10 | Ivax International Gmbh | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| WO2015085004A1 (en) | 2013-12-03 | 2015-06-11 | Intra-Cellular Therapies, Inc. | Novel methods |
| KR20170012210A (ko) * | 2014-04-04 | 2017-02-02 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 유기 화합물 |
| WO2017105881A1 (en) * | 2015-12-15 | 2017-06-22 | NeuForm Pharmaceuticals, Inc. | Deuterated compounds for treating pain |
| DK3407889T3 (da) | 2016-03-25 | 2021-08-09 | Intra Cellular Therapies Inc | Organiske forbindelser og deres anvendelse til behandling og forebyggelse af lidelser i centralnervesystemet |
| US11331316B2 (en) | 2016-10-12 | 2022-05-17 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
| CN106588817A (zh) * | 2016-12-13 | 2017-04-26 | 湖南亚大制药有限公司 | 一种盐酸乙哌立松的合成方法 |
| WO2018175969A1 (en) | 2017-03-24 | 2018-09-27 | Intra-Cellular Therapies, Inc. | Novel compositions and methods |
| US12144808B2 (en) | 2018-08-29 | 2024-11-19 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| JP7546546B2 (ja) | 2018-08-31 | 2024-09-06 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規方法 |
| AU2019331490B2 (en) | 2018-08-31 | 2025-04-24 | Intra-Cellular Therapies, Inc. | Novel methods |
| EP4134101A1 (en) | 2019-07-07 | 2023-02-15 | Intra-Cellular Therapies, Inc. | Deuterated lumateperone for the treatment of the bipolar ii disorder |
| CN110845443B (zh) * | 2019-12-11 | 2023-09-05 | 嘉实（湖南）医药科技有限公司 | 一种制备高纯度盐酸托哌酮的方法 |
| US12414948B2 (en) | 2022-05-18 | 2025-09-16 | Intra-Cellular Therapies, Inc. | Methods |
| CN117003605B (zh) * | 2023-08-07 | 2024-06-11 | 宁波萃英化学技术有限公司 | 一种氘代萘基蒽类化合物的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5527914B2 (is) * | 1973-12-14 | 1980-07-24 | ||
| US3995047A (en) * | 1973-12-14 | 1976-11-30 | Eisai Co., Ltd. | Propiophenone derivatives in the treatment of pathological muscular conditions |
| US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
| HU33131A (is) * | 1984-01-26 | 1984-10-29 |
-
2001
- 2001-05-02 DE DE10123129A patent/DE10123129A1/de not_active Withdrawn
-
2002
- 2002-04-29 AU AU2002257562A patent/AU2002257562B2/en not_active Ceased
- 2002-04-29 RU RU2003133924/04A patent/RU2296755C2/ru not_active IP Right Cessation
- 2002-04-29 WO PCT/DE2002/001607 patent/WO2002088100A2/de not_active Ceased
- 2002-04-29 SI SI200230177T patent/SI1383752T1/sl unknown
- 2002-04-29 US US10/476,743 patent/US7307091B2/en not_active Expired - Lifetime
- 2002-04-29 JP JP2002585402A patent/JP4373097B2/ja not_active Expired - Fee Related
- 2002-04-29 CA CA2446890A patent/CA2446890C/en not_active Expired - Fee Related
- 2002-04-29 KR KR1020037014301A patent/KR100894846B1/ko not_active Expired - Fee Related
- 2002-04-29 CN CNB028106121A patent/CN1293064C/zh not_active Expired - Fee Related
- 2002-04-29 CZ CZ20033060A patent/CZ20033060A3/cs unknown
- 2002-04-29 DK DK02727303T patent/DK1383752T3/da active
- 2002-04-29 EP EP02727303A patent/EP1383752B1/de not_active Expired - Lifetime
- 2002-04-29 IL IL15866802A patent/IL158668A0/xx unknown
- 2002-04-29 HU HU0400077A patent/HUP0400077A2/hu unknown
- 2002-04-29 DE DE50203456T patent/DE50203456D1/de not_active Expired - Lifetime
- 2002-04-29 PL PL02363313A patent/PL363313A1/xx unknown
- 2002-04-29 PT PT02727303T patent/PT1383752E/pt unknown
- 2002-04-29 CN CNA2006101485698A patent/CN101002770A/zh active Pending
- 2002-04-29 NZ NZ529586A patent/NZ529586A/en unknown
- 2002-04-29 AT AT02727303T patent/ATE298324T1/de not_active IP Right Cessation
- 2002-04-29 ES ES02727303T patent/ES2244768T3/es not_active Expired - Lifetime
-
2003
- 2003-10-30 IS IS7006A patent/IS7006A/is unknown
- 2003-10-31 NO NO20034863A patent/NO20034863L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE10123129A1 (de) | 2002-11-14 |
| ES2244768T3 (es) | 2005-12-16 |
| IL158668A0 (en) | 2004-05-12 |
| SI1383752T1 (sl) | 2005-12-31 |
| ATE298324T1 (de) | 2005-07-15 |
| DE50203456D1 (de) | 2005-07-28 |
| JP4373097B2 (ja) | 2009-11-25 |
| KR100894846B1 (ko) | 2009-04-24 |
| PT1383752E (pt) | 2005-11-30 |
| WO2002088100A2 (de) | 2002-11-07 |
| DK1383752T3 (da) | 2005-10-17 |
| RU2296755C2 (ru) | 2007-04-10 |
| JP2004527558A (ja) | 2004-09-09 |
| PL363313A1 (en) | 2004-11-15 |
| KR20040015240A (ko) | 2004-02-18 |
| CN1527823A (zh) | 2004-09-08 |
| US7307091B2 (en) | 2007-12-11 |
| AU2002257562B2 (en) | 2007-01-11 |
| NO20034863L (no) | 2003-12-30 |
| EP1383752B1 (de) | 2005-06-22 |
| US20040186136A1 (en) | 2004-09-23 |
| RU2003133924A (ru) | 2005-05-10 |
| CA2446890C (en) | 2010-02-23 |
| WO2002088100A3 (de) | 2003-05-30 |
| CN1293064C (zh) | 2007-01-03 |
| NO20034863D0 (no) | 2003-10-31 |
| HUP0400077A2 (hu) | 2004-04-28 |
| CZ20033060A3 (cs) | 2004-09-15 |
| CN101002770A (zh) | 2007-07-25 |
| CA2446890A1 (en) | 2002-11-07 |
| NZ529586A (en) | 2005-07-29 |
| EP1383752A2 (de) | 2004-01-28 |
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