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IS6663A - Indólafleiður sem eru nytsamlegar við meðhöndlun á MTK-truflunum - Google Patents

Indólafleiður sem eru nytsamlegar við meðhöndlun á MTK-truflunum

Info

Publication number
IS6663A
IS6663A IS6663A IS6663A IS6663A IS 6663 A IS6663 A IS 6663A IS 6663 A IS6663 A IS 6663A IS 6663 A IS6663 A IS 6663A IS 6663 A IS6663 A IS 6663A
Authority
IS
Iceland
Prior art keywords
mtk
disorders
treatment
indole derivatives
derivatives useful
Prior art date
Application number
IS6663A
Other languages
English (en)
Other versions
IS2172B (is
Inventor
Felding Jakob
Bang-Andersen Benny
Paul Smith Garrick
Andersen Kim
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of IS6663A publication Critical patent/IS6663A/is
Publication of IS2172B publication Critical patent/IS2172B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IS6663A 2000-07-21 2002-12-23 Indól afleiður sem eru nytsamlegar fyrir meðhöndlun á taugakerfistruflunum IS2172B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001123 2000-07-21
PCT/DK2001/000507 WO2002008223A1 (en) 2000-07-21 2001-07-17 Indole derivatives useful for the treatment of cns disorders

Publications (2)

Publication Number Publication Date
IS6663A true IS6663A (is) 2002-12-23
IS2172B IS2172B (is) 2006-11-15

Family

ID=8159625

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6663A IS2172B (is) 2000-07-21 2002-12-23 Indól afleiður sem eru nytsamlegar fyrir meðhöndlun á taugakerfistruflunum

Country Status (28)

Country Link
US (1) US6743809B2 (is)
EP (1) EP1305307B1 (is)
JP (1) JP2004504396A (is)
KR (1) KR100851793B1 (is)
CN (1) CN1264838C (is)
AR (1) AR029858A1 (is)
AT (1) ATE266024T1 (is)
AU (2) AU8173801A (is)
BG (1) BG107528A (is)
BR (1) BR0112998A (is)
CA (1) CA2416212C (is)
CZ (1) CZ301114B6 (is)
DE (1) DE60103162T2 (is)
EA (1) EA004749B1 (is)
ES (1) ES2219554T3 (is)
HR (1) HRP20030015A2 (is)
HU (1) HUP0302820A3 (is)
IL (2) IL153605A0 (is)
IS (1) IS2172B (is)
MX (1) MXPA02012927A (is)
NO (1) NO323799B1 (is)
NZ (1) NZ523436A (is)
PT (1) PT1305307E (is)
SK (1) SK286701B6 (is)
TR (1) TR200401488T4 (is)
UA (1) UA73995C2 (is)
WO (1) WO2002008223A1 (is)
ZA (1) ZA200300287B (is)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2545261C (en) 2003-11-17 2013-07-23 Boehringer Ingelheim International Gmbh Piperidine-substituted indoles- or heteroderivatives thereof
TWI391387B (zh) * 2004-05-12 2013-04-01 Eisai R&D Man Co Ltd 具有哌啶環之吲哚衍生物
JP5080450B2 (ja) 2005-04-30 2012-11-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なピペリジン置換インドール
CA2667547C (en) 2006-10-27 2014-07-29 Boehringer Ingelheim International Gmbh Piperidyl-propane-thiol ccr3 modulators
CN101486654B (zh) * 2009-03-04 2012-10-10 西安近代化学研究所 2-甲基-3-硝基苯乙酸合成方法
CN110041318B (zh) * 2018-01-17 2022-07-29 中国科学院上海药物研究所 一类多巴胺d5受体激动剂及其制备和应用
CN110498789B (zh) * 2018-05-17 2022-04-05 上海医药工业研究院 芳烷哌啶类衍生物及其在多靶点抗抑郁症中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
AT332401B (de) * 1973-11-26 1976-09-27 Roussel Uclaf Verfahren zur herstellung von neuen (4'-(3''-indolyl)-piperidino)-alkylarylketonderivaten
GB8719167D0 (en) 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
IE61488B1 (en) * 1987-08-13 1994-11-02 Glaxo Group Ltd Indole derivatives
JPH08501287A (ja) * 1992-08-05 1996-02-13 ジョン・ワイス・アンド・ブラザー・リミテッド アミド誘導体
NZ265269A (en) * 1993-04-22 1996-09-25 Pfizer Research & Dev Co Substituted indole derivatives, preparation and medicaments thereof
ES2063700B1 (es) * 1993-04-28 1995-07-16 Vita Invest Sa Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9718712D0 (en) * 1997-09-03 1997-11-12 Merck Sharp & Dohme Theraputic Agents

Also Published As

Publication number Publication date
CA2416212A1 (en) 2002-01-31
AU8173801A (en) 2002-02-05
HRP20030015A2 (en) 2005-02-28
IL153605A (en) 2008-07-08
HUP0302820A3 (en) 2006-04-28
SK286701B6 (sk) 2009-03-05
CA2416212C (en) 2007-10-30
NO20030127D0 (no) 2003-01-10
MXPA02012927A (es) 2003-05-15
CZ2003196A3 (cs) 2003-05-14
UA73995C2 (en) 2005-10-17
EA200300179A1 (ru) 2003-06-26
US20030166664A1 (en) 2003-09-04
EP1305307B1 (en) 2004-05-06
PL359157A1 (en) 2004-08-23
CN1264838C (zh) 2006-07-19
TR200401488T4 (tr) 2004-08-23
IS2172B (is) 2006-11-15
US6743809B2 (en) 2004-06-01
WO2002008223A1 (en) 2002-01-31
DE60103162D1 (de) 2004-06-09
AR029858A1 (es) 2003-07-16
DE60103162T2 (de) 2005-05-04
AU2001281738B2 (en) 2006-12-21
ZA200300287B (en) 2004-03-02
BR0112998A (pt) 2003-06-24
HK1059782A1 (en) 2004-07-16
IL153605A0 (en) 2003-07-06
KR20030017643A (ko) 2003-03-03
EA004749B1 (ru) 2004-08-26
EP1305307A1 (en) 2003-05-02
NO323799B1 (no) 2007-07-09
PT1305307E (pt) 2004-09-30
KR100851793B1 (ko) 2008-08-13
CZ301114B6 (cs) 2009-11-11
ATE266024T1 (de) 2004-05-15
JP2004504396A (ja) 2004-02-12
BG107528A (bg) 2003-10-31
SK2032003A3 (en) 2003-06-03
NZ523436A (en) 2004-07-30
HUP0302820A2 (hu) 2003-12-29
CN1451002A (zh) 2003-10-22
NO20030127L (no) 2003-01-10
ES2219554T3 (es) 2004-12-01

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