IN2015DN02104A - - Google Patents
Info
- Publication number
- IN2015DN02104A IN2015DN02104A IN2104DEN2015A IN2015DN02104A IN 2015DN02104 A IN2015DN02104 A IN 2015DN02104A IN 2104DEN2015 A IN2104DEN2015 A IN 2104DEN2015A IN 2015DN02104 A IN2015DN02104 A IN 2015DN02104A
- Authority
- IN
- India
- Prior art keywords
- pharmaceutically acceptable
- patient
- methods
- need
- disclosed compounds
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- IHTABYJTVMTSMK-UHFFFAOYSA-N 2-[(4-aminophenyl)methyl]-2-methoxy-3-oxobutanoic acid Chemical compound COC(C(O)=O)(C(C)=O)CC1=CC=C(N)C=C1 IHTABYJTVMTSMK-UHFFFAOYSA-N 0.000 abstract 1
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 231100000360 alopecia Toxicity 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000003780 hair follicle Anatomy 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
Provided herein are methods for enhancing epidermal regeneration in a patient in need thereof comprising topically administering to said patient a pharmaceutically acceptable composition comprising N acetyl 3 (4 aminophenyl) 2 methoxypropionic acid or a pharmaceutically acceptable salt or stereoisomer thereof and a pharmaceutically acceptable excipient. For example provided are methods for treating or ameliorating cicatricial alopecia comprising topically administering to a patient in need thereof a pharmaceutically acceptable composition comprising the disclosed compounds. Also provided are methods for protecting hair follicle progenitor cells and compositions comprising same using the disclosed compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261700623P | 2012-09-13 | 2012-09-13 | |
| PCT/EP2013/069062 WO2014041140A1 (en) | 2012-09-13 | 2013-09-13 | Methods of treating hair related conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN02104A true IN2015DN02104A (en) | 2015-08-14 |
Family
ID=49170707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2104DEN2015 IN2015DN02104A (en) | 2012-09-13 | 2013-09-13 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20150250749A1 (en) |
| EP (1) | EP2895160B1 (en) |
| JP (1) | JP2015528479A (en) |
| KR (1) | KR20150054934A (en) |
| CN (1) | CN104837486A (en) |
| AU (1) | AU2013314288B2 (en) |
| BR (1) | BR112015005467A2 (en) |
| CA (1) | CA2883823A1 (en) |
| CY (1) | CY1120793T1 (en) |
| DK (1) | DK2895160T3 (en) |
| EA (1) | EA035986B1 (en) |
| ES (1) | ES2675169T3 (en) |
| HR (1) | HRP20181000T1 (en) |
| HU (1) | HUE037903T2 (en) |
| IL (1) | IL237449A0 (en) |
| IN (1) | IN2015DN02104A (en) |
| LT (1) | LT2895160T (en) |
| MX (1) | MX356888B (en) |
| NZ (1) | NZ705389A (en) |
| PL (1) | PL2895160T3 (en) |
| PT (1) | PT2895160T (en) |
| SI (1) | SI2895160T1 (en) |
| TR (1) | TR201809219T4 (en) |
| UA (1) | UA116215C2 (en) |
| WO (1) | WO2014041140A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20050389A1 (en) | 2005-07-22 | 2007-01-23 | Giuliani Spa | COMPOUNDS AND THEIR SPECIFIC SALTS FOR PPAR RECEPTORS AND RECEPTORS FOR EGF AND THEIR USE IN MEDICAL FIELDS. |
| UA107562C2 (en) | 2008-12-05 | 2015-01-26 | METHOD OF TREATMENT OF PSORIASIS | |
| PT2396081T (en) | 2009-02-16 | 2017-07-11 | Nogra Pharma Ltd | Alkylamido compounds and uses thereof |
| EP2811993B1 (en) | 2012-02-09 | 2019-10-09 | Nogra Pharma Limited | Methods of treating fibrosis |
| IN2014DN08157A (en) | 2012-04-18 | 2015-05-01 | Nogra Pharma Ltd | |
| SI3921299T1 (en) | 2019-02-08 | 2025-03-31 | Nogra Pharma Limited | Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof |
| WO2025132838A1 (en) * | 2023-12-20 | 2025-06-26 | Nogra Pharma Limited | Acne topical formulations |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2396081T (en) * | 2009-02-16 | 2017-07-11 | Nogra Pharma Ltd | Alkylamido compounds and uses thereof |
| IN2014DN08157A (en) * | 2012-04-18 | 2015-05-01 | Nogra Pharma Ltd |
-
2013
- 2013-09-13 LT LTEP13762485.4T patent/LT2895160T/en unknown
- 2013-09-13 EP EP13762485.4A patent/EP2895160B1/en active Active
- 2013-09-13 HR HRP20181000TT patent/HRP20181000T1/en unknown
- 2013-09-13 NZ NZ705389A patent/NZ705389A/en not_active IP Right Cessation
- 2013-09-13 PL PL13762485T patent/PL2895160T3/en unknown
- 2013-09-13 CA CA2883823A patent/CA2883823A1/en not_active Abandoned
- 2013-09-13 BR BR112015005467A patent/BR112015005467A2/en active Search and Examination
- 2013-09-13 DK DK13762485.4T patent/DK2895160T3/en active
- 2013-09-13 WO PCT/EP2013/069062 patent/WO2014041140A1/en not_active Ceased
- 2013-09-13 TR TR2018/09219T patent/TR201809219T4/en unknown
- 2013-09-13 AU AU2013314288A patent/AU2013314288B2/en not_active Ceased
- 2013-09-13 US US14/428,164 patent/US20150250749A1/en not_active Abandoned
- 2013-09-13 UA UAA201503407A patent/UA116215C2/en unknown
- 2013-09-13 CN CN201380047941.4A patent/CN104837486A/en active Pending
- 2013-09-13 EA EA201590546A patent/EA035986B1/en not_active IP Right Cessation
- 2013-09-13 SI SI201331087T patent/SI2895160T1/en unknown
- 2013-09-13 JP JP2015531580A patent/JP2015528479A/en active Pending
- 2013-09-13 MX MX2015003278A patent/MX356888B/en active IP Right Grant
- 2013-09-13 HU HUE13762485A patent/HUE037903T2/en unknown
- 2013-09-13 IN IN2104DEN2015 patent/IN2015DN02104A/en unknown
- 2013-09-13 KR KR1020157009052A patent/KR20150054934A/en not_active Withdrawn
- 2013-09-13 ES ES13762485.4T patent/ES2675169T3/en active Active
- 2013-09-13 PT PT137624854T patent/PT2895160T/en unknown
-
2015
- 2015-02-26 IL IL237449A patent/IL237449A0/en unknown
-
2018
- 2018-06-28 CY CY20181100673T patent/CY1120793T1/en unknown
-
2020
- 2020-06-04 US US16/892,513 patent/US20210113505A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2883823A1 (en) | 2014-03-20 |
| AU2013314288A1 (en) | 2015-03-19 |
| MX356888B (en) | 2018-06-18 |
| ES2675169T3 (en) | 2018-07-09 |
| CY1120793T1 (en) | 2020-05-29 |
| BR112015005467A2 (en) | 2017-07-04 |
| UA116215C2 (en) | 2018-02-26 |
| LT2895160T (en) | 2018-07-10 |
| WO2014041140A1 (en) | 2014-03-20 |
| EP2895160A1 (en) | 2015-07-22 |
| US20150250749A1 (en) | 2015-09-10 |
| NZ705389A (en) | 2018-08-31 |
| PL2895160T3 (en) | 2018-09-28 |
| US20210113505A1 (en) | 2021-04-22 |
| DK2895160T3 (en) | 2018-06-25 |
| SI2895160T1 (en) | 2018-09-28 |
| JP2015528479A (en) | 2015-09-28 |
| EA201590546A1 (en) | 2015-08-31 |
| MX2015003278A (en) | 2015-07-06 |
| EA035986B1 (en) | 2020-09-09 |
| CN104837486A (en) | 2015-08-12 |
| HRP20181000T1 (en) | 2018-09-21 |
| IL237449A0 (en) | 2015-04-30 |
| TR201809219T4 (en) | 2018-07-23 |
| KR20150054934A (en) | 2015-05-20 |
| PT2895160T (en) | 2018-06-29 |
| EP2895160B1 (en) | 2018-05-30 |
| AU2013314288B2 (en) | 2018-07-05 |
| HUE037903T2 (en) | 2018-09-28 |
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