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PH12013500679A1 - Topical gel composition - Google Patents

Topical gel composition

Info

Publication number
PH12013500679A1
PH12013500679A1 PH1/2013/500679A PH12013500679A PH12013500679A1 PH 12013500679 A1 PH12013500679 A1 PH 12013500679A1 PH 12013500679 A PH12013500679 A PH 12013500679A PH 12013500679 A1 PH12013500679 A1 PH 12013500679A1
Authority
PH
Philippines
Prior art keywords
topical gel
gel composition
paraben
gel compositions
treatment
Prior art date
Application number
PH1/2013/500679A
Inventor
Jean-Christophe Buge
Cyril Meunier
Fourcade Karine Nadau
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR1058611A external-priority patent/FR2966365B1/en
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of PH12013500679A1 publication Critical patent/PH12013500679A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

Improved topical gel compositions, such as those containing brimonidine for the treatment of skin disorders are described. The gel compositions contain carbomer and paraben, and are substantially free of paraben crystalline particles after an extended period of storage.
PH1/2013/500679A 2010-10-21 2011-10-19 Topical gel composition PH12013500679A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40538210P 2010-10-21 2010-10-21
FR1058611A FR2966365B1 (en) 2010-10-21 2010-10-21 TOPICAL GEL COMPOSITION
PCT/EP2011/068261 WO2012052478A2 (en) 2010-10-21 2011-10-19 Topical gel composition

Publications (1)

Publication Number Publication Date
PH12013500679A1 true PH12013500679A1 (en) 2013-06-10

Family

ID=45065557

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2013/500679A PH12013500679A1 (en) 2010-10-21 2011-10-19 Topical gel composition

Country Status (14)

Country Link
EP (1) EP2605753A2 (en)
JP (1) JP2013540142A (en)
KR (1) KR20130101552A (en)
CN (1) CN103313700A (en)
AU (1) AU2011317642A1 (en)
BR (1) BR112013009577A2 (en)
CA (1) CA2814975A1 (en)
IL (1) IL225775A0 (en)
MX (1) MX2013004472A (en)
PH (1) PH12013500679A1 (en)
RU (1) RU2013123043A (en)
SG (1) SG189338A1 (en)
WO (1) WO2012052478A2 (en)
ZA (1) ZA201302812B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140074883A (en) * 2011-07-14 2014-06-18 알러간, 인코포레이티드 Gel compositions of oxymetazoline and methods of use
CN104666239A (en) * 2013-11-27 2015-06-03 杭州赛利药物研究所有限公司 Brimonidine tartrate gel and preparation method thereof
CN103919717A (en) * 2014-04-15 2014-07-16 天津中医药大学 Brimonidine d-tartrate ophthalmic gel preparation as well as preparation method and application thereof
EP3476393A4 (en) * 2016-06-28 2019-07-17 Doris Maria Hexsel USE OF AN ACTIVE SUBSTANCE IN THE TREATMENT OF TELANGIECTASIC MELASMS
BR112021020962A2 (en) 2019-05-01 2021-12-14 Clexio Biosciences Ltd Pruritus treatment methods
CN110882211A (en) * 2019-12-31 2020-03-17 深圳市瀚德标检生物工程有限公司 Hydroxyphenyl ester gel and preparation method thereof
CN116159018B (en) * 2023-03-01 2024-11-01 中国药科大学 Novel external use brimonidine gel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006A (en) * 1852-06-08 Improvement in seed-planters
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US20050020600A1 (en) 2003-07-23 2005-01-27 Scherer Warren J. Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists
CA2567401C (en) * 2004-05-25 2013-11-12 Sansrosa Pharmaceutical Development, Inc. Compounds, formulations, and methods for treating or preventing inflammatory skin disorders
US20090061020A1 (en) * 2007-08-31 2009-03-05 Theobald Klaus P Brimonidine Compositions for Treating Erythema
EP2818184B1 (en) 2007-11-16 2018-10-31 Allergan, Inc. Compositions and methods for treating Purpura
EP2230910A4 (en) * 2007-12-21 2011-04-13 Galderma Lab Inc Pre-surgical treatment
JP5052558B2 (en) * 2009-04-03 2012-10-17 ロート製薬株式会社 Gel ointment

Also Published As

Publication number Publication date
JP2013540142A (en) 2013-10-31
CA2814975A1 (en) 2012-04-26
RU2013123043A (en) 2014-12-10
CN103313700A (en) 2013-09-18
WO2012052478A2 (en) 2012-04-26
IL225775A0 (en) 2013-09-30
ZA201302812B (en) 2014-06-25
SG189338A1 (en) 2013-05-31
EP2605753A2 (en) 2013-06-26
AU2011317642A1 (en) 2013-05-02
KR20130101552A (en) 2013-09-13
WO2012052478A3 (en) 2012-06-14
BR112013009577A2 (en) 2016-07-12
MX2013004472A (en) 2013-10-25

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