IN2014DN03093A - - Google Patents

Info

Publication number: IN2014DN03093A
Authority: IN; India
Prior art keywords: compositions; analgesic; diketopiperazines; microparticles; administered
Prior art date: 2011-10-24

Application number

Other languages

English (en)

Inventor

Bay Andrea Leone

Richard A Houghten

Joseph J Guarneri

Grayson W Stowell

Original Assignee

Mannkind Corp

Torrey Pines Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-24

Filing date

2012-10-24

Publication date

2015-05-15

2012-10-24 Application filed by Mannkind Corp, Torrey Pines Inst filed Critical Mannkind Corp

2015-05-15 Publication of IN2014DN03093A publication Critical patent/IN2014DN03093A/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Otolaryngology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Oil, Petroleum & Natural Gas (AREA)
Pain & Pain Management (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

IN3093DEN2014 2011-10-24 2012-10-24 IN2014DN03093A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201161550860P	2011-10-24	2011-10-24
PCT/US2012/061749 WO2013063160A1 (fr)	2011-10-24	2012-10-24	Procédés et compositions pour traiter la douleur

Publications (1)

Publication Number	Publication Date
IN2014DN03093A true IN2014DN03093A (fr)	2015-05-15

Family

ID=47178332

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN3093DEN2014 IN2014DN03093A (fr)	2011-10-24	2012-10-24

Country Status (12)

Country	Link
US (3)	US9233159B2 (fr)
EP (1)	EP2776053A1 (fr)
JP (2)	JP6018640B2 (fr)
KR (1)	KR20140095483A (fr)
CN (1)	CN103945859A (fr)
AU (1)	AU2012328885B2 (fr)
BR (1)	BR112014009686A2 (fr)
CA (1)	CA2852536A1 (fr)
HK (2)	HK1201475A1 (fr)
IN (1)	IN2014DN03093A (fr)
MX (1)	MX2014004983A (fr)
WO (1)	WO2013063160A1 (fr)

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CN115991678B (zh) *	2021-10-20	2025-05-23	上海惠永药物研究有限公司	一种二酮基哌嗪类化合物、制备方法及其应用
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2012
- 2012-10-24 CA CA2852536A patent/CA2852536A1/fr not_active Abandoned
- 2012-10-24 HK HK15102104.2A patent/HK1201475A1/xx unknown
- 2012-10-24 EP EP12784825.7A patent/EP2776053A1/fr not_active Withdrawn
- 2012-10-24 US US14/354,092 patent/US9233159B2/en active Active
- 2012-10-24 JP JP2014538963A patent/JP6018640B2/ja not_active Expired - Fee Related
- 2012-10-24 MX MX2014004983A patent/MX2014004983A/es unknown
- 2012-10-24 IN IN3093DEN2014 patent/IN2014DN03093A/en unknown
- 2012-10-24 HK HK15100707.7A patent/HK1200318A1/xx unknown
- 2012-10-24 CN CN201280052401.0A patent/CN103945859A/zh active Pending
- 2012-10-24 KR KR1020147012242A patent/KR20140095483A/ko not_active Withdrawn
- 2012-10-24 BR BR112014009686A patent/BR112014009686A2/pt not_active IP Right Cessation
- 2012-10-24 WO PCT/US2012/061749 patent/WO2013063160A1/fr not_active Ceased
- 2012-10-24 AU AU2012328885A patent/AU2012328885B2/en not_active Ceased
2015
- 2015-02-13 US US14/622,660 patent/US9610351B2/en active Active
2016
- 2016-07-08 JP JP2016135940A patent/JP6165300B2/ja not_active Expired - Fee Related
2017
- 2017-02-22 US US15/439,813 patent/US10258664B2/en active Active

Also Published As

Publication number	Publication date
US9610351B2 (en)	2017-04-04
US20170209525A1 (en)	2017-07-27
JP2014530914A (ja)	2014-11-20
WO2013063160A1 (fr)	2013-05-02
HK1201475A1 (en)	2015-09-04
KR20140095483A (ko)	2014-08-01
US20140302151A1 (en)	2014-10-09
US10258664B2 (en)	2019-04-16
BR112014009686A2 (pt)	2018-08-07
US20150150980A1 (en)	2015-06-04
HK1200318A1 (en)	2015-08-07
MX2014004983A (es)	2014-09-22
CA2852536A1 (fr)	2013-05-02
EP2776053A1 (fr)	2014-09-17
AU2012328885A1 (en)	2014-04-17
JP2016222689A (ja)	2016-12-28
CN103945859A (zh)	2014-07-23
JP6018640B2 (ja)	2016-11-02
US9233159B2 (en)	2016-01-12
JP6165300B2 (ja)	2017-07-19
AU2012328885B2 (en)	2017-08-31

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