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IN2014CN03950A - - Google Patents

Info

Publication number
IN2014CN03950A
IN2014CN03950A IN3950CHN2014A IN2014CN03950A IN 2014CN03950 A IN2014CN03950 A IN 2014CN03950A IN 3950CHN2014 A IN3950CHN2014 A IN 3950CHN2014A IN 2014CN03950 A IN2014CN03950 A IN 2014CN03950A
Authority
IN
India
Prior art keywords
terpenoid
ophthalmological
polymer compound
inhibitory activity
aqueous composition
Prior art date
Application number
Inventor
Yasuko Matsumura
Chinatsu Furumiya
Masashi Itoh
Original Assignee
Rohto Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohto Pharma filed Critical Rohto Pharma
Publication of IN2014CN03950A publication Critical patent/IN2014CN03950A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention provides an ophthalmological aqueous composition containing (A) a terpenoid (B) zinc chloride and (C) at least one type selected from a group consisting of a cellulose polymer compound a vinyl polymer compound polyethylene glycol and a dextran. This ophthalmological aqueous composition: is capable of suppressing a decrease over the long term in the amount of the terpenoid contained by suppressing adsorption of the terpenoid by a container; and furthermore has excellent histamine release inhibitory activity rheum inhibitory activity and the like.
IN3950CHN2014 2011-11-01 2012-10-31 IN2014CN03950A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011240167 2011-11-01
PCT/JP2012/078128 WO2013065720A1 (en) 2011-11-01 2012-10-31 Ophthalmological aqueous composition

Publications (1)

Publication Number Publication Date
IN2014CN03950A true IN2014CN03950A (en) 2015-10-16

Family

ID=48192065

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3950CHN2014 IN2014CN03950A (en) 2011-11-01 2012-10-31

Country Status (5)

Country Link
US (1) US9173945B2 (en)
JP (2) JP6313599B2 (en)
CA (1) CA2853235A1 (en)
IN (1) IN2014CN03950A (en)
WO (1) WO2013065720A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2853235A1 (en) * 2011-11-01 2013-05-10 Rohto Pharmaceutical Co., Ltd. Ophthalmological aqueous composition
JP2016185940A (en) * 2014-06-10 2016-10-27 ロート製薬株式会社 Ophthalmic composition
JP7387835B2 (en) * 2016-04-22 2023-11-28 ロート製薬株式会社 Ophthalmic composition
JP2017197526A (en) * 2016-04-22 2017-11-02 ロート製薬株式会社 Ophthalmic composition
JP7159501B1 (en) * 2016-04-22 2022-10-24 ロート製薬株式会社 ophthalmic composition
US11331390B2 (en) 2016-04-22 2022-05-17 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
JP2017197524A (en) * 2016-04-22 2017-11-02 ロート製薬株式会社 Ophthalmic composition
JP7125250B2 (en) * 2016-04-22 2022-08-24 ロート製薬株式会社 ophthalmic composition
US11583496B2 (en) 2016-10-12 2023-02-21 PS Therapy Inc. Drug vehicle compositions and methods of use thereof
US11260035B2 (en) 2016-10-12 2022-03-01 Ps Therapies Ltd Topical compositions and methods of use thereof
WO2020218466A1 (en) * 2019-04-26 2020-10-29 参天製薬株式会社 Ophthalmic product and use thereof
US20240390416A1 (en) * 2021-09-30 2024-11-28 Rohto Pharmaceutical Co., Ltd. Ophthalmological composition

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8916625D0 (en) * 1989-07-20 1989-09-06 Bryce Smith Derek Respiratory tract spray preparations
JP4748289B2 (en) 2000-06-23 2011-08-17 ライオン株式会社 Eye drops, ophthalmic composition, and adsorption suppression method
JP2003146892A (en) * 2001-11-08 2003-05-21 Rohto Pharmaceut Co Ltd Cleaning agent
JP4718160B2 (en) 2003-11-12 2011-07-06 ロート製薬株式会社 Ophthalmic composition
US20050137166A1 (en) * 2003-12-19 2005-06-23 Alcon, Inc. Use of cooling agents to relieve mild ocular irritation and enhance comfort
JP5403850B2 (en) 2004-06-08 2014-01-29 ロート製薬株式会社 Ophthalmic refreshing composition
US7629386B2 (en) 2004-08-26 2009-12-08 Bausch + Lomb Incorporated Compositions containing trialkanolamine alkoxylate buffer
JP4953650B2 (en) * 2005-02-09 2012-06-13 ロート製薬株式会社 Planoprofen-containing composition
US8435965B2 (en) 2005-12-27 2013-05-07 Lion Corporation Composition for soft contact lens and adsorption suppressing method
KR101421519B1 (en) * 2006-09-28 2014-07-30 알콘 리서치, 리미티드 Self-preserved aqueous pharmaceutical compositions
JP5314349B2 (en) 2007-07-25 2013-10-16 ロート製薬株式会社 Ophthalmic composition
CN101854939B (en) 2007-09-14 2012-10-24 乐敦制药株式会社 Ophthalmic composition
BRPI0819105A2 (en) * 2007-11-08 2019-09-24 Aciex Therapeutics Inc composition for the treatment and prevention of eyelid edema
JP2008189677A (en) * 2008-03-10 2008-08-21 Rohto Pharmaceut Co Ltd Washing agent
US8669241B2 (en) * 2008-12-02 2014-03-11 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
JP4777477B2 (en) 2009-09-30 2011-09-21 ロート製薬株式会社 Eye drops
CA2853235A1 (en) * 2011-11-01 2013-05-10 Rohto Pharmaceutical Co., Ltd. Ophthalmological aqueous composition

Also Published As

Publication number Publication date
WO2013065720A1 (en) 2013-05-10
JP6313599B2 (en) 2018-04-18
JP2017052804A (en) 2017-03-16
CA2853235A1 (en) 2013-05-10
JPWO2013065720A1 (en) 2015-04-02
US20140308368A1 (en) 2014-10-16
US9173945B2 (en) 2015-11-03
JP6242998B2 (en) 2017-12-06

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