IN2012DN00866A - - Google Patents
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- Publication number
- IN2012DN00866A IN2012DN00866A IN866DEN2012A IN2012DN00866A IN 2012DN00866 A IN2012DN00866 A IN 2012DN00866A IN 866DEN2012 A IN866DEN2012 A IN 866DEN2012A IN 2012DN00866 A IN2012DN00866 A IN 2012DN00866A
- Authority
- IN
- India
- Prior art keywords
- nucleic acids
- high quality
- extractions
- quality nucleic
- prognosis
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 238000000605 extraction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22610609P | 2009-07-16 | 2009-07-16 | |
| US22602509P | 2009-07-16 | 2009-07-16 | |
| PCT/US2010/042365 WO2011009104A1 (fr) | 2009-07-16 | 2010-07-16 | Analyse d'acides nucléiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN00866A true IN2012DN00866A (fr) | 2015-07-10 |
Family
ID=43449850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN866DEN2012 IN2012DN00866A (fr) | 2009-07-16 | 2010-07-16 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20110195426A1 (fr) |
| EP (1) | EP2454588B1 (fr) |
| JP (3) | JP5909444B2 (fr) |
| KR (2) | KR20120037992A (fr) |
| CN (2) | CN105779436A (fr) |
| AU (1) | AU2010273928A1 (fr) |
| BR (1) | BR112012001077A2 (fr) |
| CA (1) | CA2768371A1 (fr) |
| DK (1) | DK2454588T3 (fr) |
| ES (1) | ES2547715T3 (fr) |
| IN (1) | IN2012DN00866A (fr) |
| SG (2) | SG2014014617A (fr) |
| WO (1) | WO2011009104A1 (fr) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2736726T3 (es) * | 2006-03-09 | 2020-01-07 | Aethlon Medical Inc | Eliminación extracorpórea de partículas microvesiculares |
| US11266736B2 (en) | 2008-04-17 | 2022-03-08 | Vin De Bona Trading Company Pte Ltd | Method of painting micro vesicles |
| EP3461912B1 (fr) * | 2009-09-09 | 2022-07-13 | The General Hospital Corporation | Utilisation de microvésicules dans l'analyse de profils d'acides nucléiques |
| EP2475989A4 (fr) | 2009-09-09 | 2013-02-27 | Gen Hospital Corp | Utilisation de microvésicules dans l'analyse de mutations kras |
| JP5755326B2 (ja) * | 2010-06-11 | 2015-07-29 | 日立化成株式会社 | 腎機能の特徴を決定する方法 |
| US20140045915A1 (en) | 2010-08-31 | 2014-02-13 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| EP2638057B1 (fr) * | 2010-11-10 | 2019-03-06 | Exosome Diagnostics, Inc. | Procédés d'isolement de particules contenant des acides nucléiques et extraction d'acides nucléiques à partir de celles-ci |
| US20120196285A1 (en) * | 2011-01-31 | 2012-08-02 | Esoterix Genetic Laboratories, Llc | Methods for Enriching Microparticles or Nucleic Acids Using Binding Molecules |
| EP3569607A1 (fr) | 2011-05-11 | 2019-11-20 | Exosome Diagnostics, Inc. | Extraction d'acide nucléique à partir de matériaux biologiques hétérogènes |
| WO2012170037A1 (fr) | 2011-06-10 | 2012-12-13 | Hitachi Chemical Co., Ltd. | Dispositifs de capture de vésicule et leurs procédés d'utilisation |
| EP2748335B1 (fr) | 2011-08-22 | 2018-10-03 | Exosome Diagnostics, Inc. | Marqueurs biologiques d'urine |
| US10174361B2 (en) * | 2011-11-10 | 2019-01-08 | Exosome Diagnostics, Inc. | Cerebrospinal fluid assay |
| CN104995311A (zh) | 2012-08-30 | 2015-10-21 | 外来体诊断公司 | 用于核酸测定的对照 |
| CN105025878A (zh) * | 2012-10-03 | 2015-11-04 | 外来体诊断公司 | 微泡在医学疾病和病况的诊断、预后和治疗中的用途 |
| US20150275301A1 (en) * | 2012-10-05 | 2015-10-01 | Hitachi Chemical Co., Ltd. | URINE EXOSOME mRNAS AND METHODS OF USING SAME TO DETECT DIABETIC NEPHROPATHY |
| DK2906717T3 (en) | 2012-10-11 | 2019-04-01 | Vin De Bona Trading Company Pte Ltd | PROCEDURE FOR PAINTING MICROVESICS |
| CN105209881B (zh) | 2013-03-13 | 2021-01-22 | 迈阿密大学 | 从细胞培养上清液和生物流体分离并纯化微泡的方法 |
| DE212013000295U1 (de) | 2013-05-06 | 2016-02-02 | Hitachi Chemical Co. America, Ltd. | Vorrichtungen zum Einfangen von Zielmolekülen |
| US10301681B2 (en) | 2013-08-06 | 2019-05-28 | Exosome Diagnostics, Inc. | Methods of treating a subject with a high gleason score prostate cancer |
| ES2923942T3 (es) | 2013-11-06 | 2022-10-03 | Us Health | Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión |
| US10494676B2 (en) * | 2013-12-02 | 2019-12-03 | Albert-Ludwigs-Universitaet Freiburg | Process for the diagnosis of cancer by using exosomes |
| EP3125907A4 (fr) | 2014-04-01 | 2017-11-29 | Cornell University | Utilisation d'adn double brin dans des exosomes : un nouveau biomarqueur dans la détection du cancer |
| WO2015164435A1 (fr) * | 2014-04-22 | 2015-10-29 | Trovagene, Inc. | Concentration d'acides nucléique dans l'urine |
| CN104031915A (zh) * | 2014-06-17 | 2014-09-10 | 复旦大学附属肿瘤医院 | 用于结直肠癌预后的基因片段及其应用 |
| US10266895B2 (en) | 2014-11-05 | 2019-04-23 | Hitachi Chemical Company Ltd. | Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease |
| WO2016077537A1 (fr) | 2014-11-12 | 2016-05-19 | Hitachi Chemical Co., Ltd. | Procédé et dispositif permettant de diagnostiquer une lésion touchant un organe |
| WO2016172598A1 (fr) * | 2015-04-22 | 2016-10-27 | The Broad Institute Inc. | Exosomes et leurs utilisations |
| GB2539497A (en) | 2015-06-19 | 2016-12-21 | Airbus Operations Ltd | A Rotational Joint For An Aircraft Folding Wing |
| WO2017040520A1 (fr) | 2015-08-31 | 2017-03-09 | Hitachi Chemical Co., Ltd. | Méthodes moléculaires pour évaluer une maladie urothéliale |
| US11702702B2 (en) | 2016-04-15 | 2023-07-18 | Predicine, Inc. | Systems and methods for detecting genetic alterations |
| WO2017197399A1 (fr) * | 2016-05-13 | 2017-11-16 | Exosome Diagnostics, Inc. | Procédés automatisés et manuels pour l'isolement de vésicules extracellulaires et l'isolement conjoint d'adn acellulaire à partir de bioliquides |
| US11174503B2 (en) | 2016-09-21 | 2021-11-16 | Predicine, Inc. | Systems and methods for combined detection of genetic alterations |
| CN110945145B (zh) | 2017-05-17 | 2024-06-11 | 外来体诊断公司 | 微泡核酸和/或蛋白及其作为肾移植排斥的标志物的应用 |
| EP3652315A4 (fr) | 2017-07-12 | 2021-09-01 | Exosome Diagnostics, Inc. | Procédés d'isolement et d'enrichissement de populations de vésicules extracellulaires dérivées de biofluides, et procédés d'utilisation associés |
| JP7069587B2 (ja) * | 2017-07-31 | 2022-05-18 | 東ソー株式会社 | 分析機器の洗浄方法 |
| WO2019116234A1 (fr) * | 2017-12-12 | 2019-06-20 | Nestec S.A. | Procédés de détermination de variations de composition d'arn ribosomique de microbiome |
| JP7444386B2 (ja) * | 2018-06-07 | 2024-03-06 | 株式会社Ｌｓｉメディエンス | ヒト尿からのマイクロベシクルの分離方法及び分析方法 |
| WO2020106853A1 (fr) | 2018-11-20 | 2020-05-28 | Exosome Diagnostics, Inc. | Compositions et procédés de témoins internes d'isolements de microvésicules |
| CN109856259A (zh) * | 2018-12-29 | 2019-06-07 | 南通大学附属医院 | 一种血清胰腺癌外泌体特异蛋白及其再验证过程 |
| CN111593093B (zh) * | 2020-03-09 | 2022-03-04 | 中山大学 | 一种获取adar蛋白细胞内高效结合的底物序列的方法及底物序列和应用 |
| US20230203587A1 (en) | 2020-05-29 | 2023-06-29 | Exosome Diagnostics, Inc. | Use of microvesicle signature for the diagnosis and treatment of kidney transplant rejection |
| CA3190604A1 (fr) | 2020-08-15 | 2022-02-24 | Regeneron Pharmaceuticals, Inc. | Traitement de l'obesite chez des sujets ayant des molecules d'acide nucleique variantes codant pour le recepteur de la calcitonine (calcr) |
| US20250075258A1 (en) | 2021-07-16 | 2025-03-06 | Exosome Diagnostics, Inc. | Methods of detecting sjogren's syndrome using salivary exosomes |
| KR20240161644A (ko) | 2022-02-18 | 2024-11-12 | 엑소좀 디아그노스틱스, 인크. | 신장 장애의 식별 및 치료에 있어서의 미세 소포 시그니처의 용도 |
| CN114480656B (zh) * | 2022-03-07 | 2023-12-26 | 温州医科大学附属眼视光医院 | Slc12a3和/或slc12a9在作为葡萄膜黑色素瘤治疗和预后检测指标中的应用 |
| WO2024054572A1 (fr) | 2022-09-07 | 2024-03-14 | Exosome Diagnostics, Inc. | Procédés de détection du syndrome de sjögren à l'aide d'exosomes salivaires |
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| US20080287669A1 (en) * | 2007-05-16 | 2008-11-20 | Braman Jeffrey C | Methods and compositions for identifying compounds useful in nucleic acid purification |
| CA2676113C (fr) * | 2007-07-25 | 2014-07-08 | University Of Louisville Research Foundation, Inc. | Micro arn associe a l'exosome en tant que marqueur de diagnostic |
| EP2176665B1 (fr) * | 2007-08-16 | 2016-03-02 | The Royal Institution for the Advancement of Learning / McGill University | Microvesicules issues d'une cellule tumorale |
| EP2198296B1 (fr) * | 2007-09-05 | 2015-11-11 | Laurentian University | Procédé d'utilisation de l'intégrité d'arn tumoral pour mesurer la réponse à la chimiothérapie chez des patients atteints de cancer |
| US8455199B2 (en) * | 2007-09-14 | 2013-06-04 | The Ohio State University Research Foundation | MicroRNA expression in human peripheral blood microvesicles and uses thereof |
| EP2604704B1 (fr) * | 2008-02-01 | 2018-10-03 | The General Hospital Corporation | Utilisation de microvésicules pour le diagnostic et le pronostic de la tumeur cérébrale |
-
2010
- 2010-07-16 US US12/838,413 patent/US20110195426A1/en not_active Abandoned
- 2010-07-16 CN CN201610128465.4A patent/CN105779436A/zh active Pending
- 2010-07-16 CN CN201080041496.7A patent/CN102498397B/zh active Active
- 2010-07-16 IN IN866DEN2012 patent/IN2012DN00866A/en unknown
- 2010-07-16 AU AU2010273928A patent/AU2010273928A1/en not_active Abandoned
- 2010-07-16 WO PCT/US2010/042365 patent/WO2011009104A1/fr not_active Ceased
- 2010-07-16 DK DK10800649.5T patent/DK2454588T3/en active
- 2010-07-16 EP EP10800649.5A patent/EP2454588B1/fr active Active
- 2010-07-16 BR BR112012001077-8A patent/BR112012001077A2/pt not_active IP Right Cessation
- 2010-07-16 CA CA2768371A patent/CA2768371A1/fr not_active Abandoned
- 2010-07-16 SG SG2014014617A patent/SG2014014617A/en unknown
- 2010-07-16 ES ES10800649.5T patent/ES2547715T3/es active Active
- 2010-07-16 KR KR1020127003940A patent/KR20120037992A/ko not_active Ceased
- 2010-07-16 SG SG2012003141A patent/SG177677A1/en unknown
- 2010-07-16 KR KR1020187006847A patent/KR20180029105A/ko not_active Ceased
- 2010-07-16 JP JP2012520829A patent/JP5909444B2/ja active Active
-
2015
- 2015-12-17 JP JP2015246006A patent/JP2016116512A/ja active Pending
-
2016
- 2016-07-11 US US15/206,747 patent/US20160348095A1/en not_active Abandoned
- 2016-12-09 US US15/374,766 patent/US20170114389A1/en not_active Abandoned
-
2017
- 2017-04-25 JP JP2017086218A patent/JP2017131244A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20160348095A1 (en) | 2016-12-01 |
| BR112012001077A2 (pt) | 2020-08-11 |
| JP5909444B2 (ja) | 2016-04-26 |
| AU2010273928A2 (en) | 2012-02-09 |
| CN102498397B (zh) | 2016-04-06 |
| KR20180029105A (ko) | 2018-03-19 |
| SG2014014617A (en) | 2014-05-29 |
| CN105779436A (zh) | 2016-07-20 |
| HK1171083A1 (zh) | 2013-03-15 |
| EP2454588A1 (fr) | 2012-05-23 |
| WO2011009104A1 (fr) | 2011-01-20 |
| EP2454588B1 (fr) | 2015-07-15 |
| US20110195426A1 (en) | 2011-08-11 |
| EP2454588A4 (fr) | 2012-12-12 |
| CA2768371A1 (fr) | 2011-01-20 |
| SG177677A1 (en) | 2012-02-28 |
| ES2547715T3 (es) | 2015-10-08 |
| JP2012533308A (ja) | 2012-12-27 |
| KR20120037992A (ko) | 2012-04-20 |
| US20170114389A1 (en) | 2017-04-27 |
| JP2017131244A (ja) | 2017-08-03 |
| AU2010273928A1 (en) | 2012-02-09 |
| HK1173213A1 (en) | 2013-05-10 |
| JP2016116512A (ja) | 2016-06-30 |
| DK2454588T3 (en) | 2015-09-28 |
| CN102498397A (zh) | 2012-06-13 |
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