IN2013CH00918AIN918CH2013AIN2013CH00918AIN 2013CH00918 AIN2013CH00918 AIN 2013CH00918AIN 918CH2013 AIN918CH2013 AIN 918CH2013AIN 2013CH00918 AIN2013CH00918 AIN 2013CH00918A
Authority
IN
India
Prior art keywords
oxadiazol
benzimidazole
biphenyl
dihydro
oxo
Prior art date
Application number
Inventor
Thirumalai Rajan Srinivasan
Rama Subba Reddy Karamala
Original Assignee
Msn Lab Ltd
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Publication date
Application filed by Msn Lab LtdfiledCriticalMsn Lab Ltd
Priority to IN918CH2013priorityCriticalpatent/IN2013CH00918A/en
Priority to PCT/IN2013/000367prioritypatent/WO2013186792A2/en
Publication of IN2013CH00918ApublicationCriticalpatent/IN2013CH00918A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The present invention relates to an improved process for the preparation of 2-ethoxy-1 - {[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl} -1H-benzimidazole-7-carboxylic acid compound of formula-2, its derivatives and their pharmaceutically acceptable salts thereof.
Process for the preparation of (5-methyl-2-oxo-l,3-dioxoi-4-vl)methvl 2- ethoxv-l-{[2'-(5-oxo-4,5-dihvdro-l,2,4-oxadiazol-3-vl)biphenyi-4-vl]methyl}- lh-benzimidazole-7-carboxyiate and its salts
PROCESS FOR THE PREPARATION OF [(5-(3-CHLOROPHENYL)-3-HYDROXYPYRIDINO-2-CARBONYL)-AMINO]ACETIC ACID FROM 5-((3-CHLOROPHENYL)-3-CHLORO-PYRIDIN-2-YL)-NITRILE, AND PROCESS FOR THE PREPARATION OF 5-((HALOPHENYL)-3-HALO-PYRIDIN-2-YL)-NITRILE DERIVATIVES
Crystalline salt form of (s)-(2-(6-chloro-7-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone as orexin receptor antagonist
METHOD OF SYNTHESIS (2E) -3- (3,4-DIMETOXIFYNEL) PROP-2-ENNITRIL AND APPLICATION IN SYNTHESIS OF IVABRADINE AND ITS ADDITIVE PHARMACYTESE PHARMACEUTICAL SALTS