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IL98463A - Synergistic antimalarial compositions containing benflumetol - Google Patents

Synergistic antimalarial compositions containing benflumetol

Info

Publication number
IL98463A
IL98463A IL9846391A IL9846391A IL98463A IL 98463 A IL98463 A IL 98463A IL 9846391 A IL9846391 A IL 9846391A IL 9846391 A IL9846391 A IL 9846391A IL 98463 A IL98463 A IL 98463A
Authority
IL
Israel
Prior art keywords
benflumetol
compound
formula
effective amount
artemether
Prior art date
Application number
IL9846391A
Other languages
English (en)
Other versions
IL98463A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25742651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL98463(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL98463A0 publication Critical patent/IL98463A0/xx
Publication of IL98463A publication Critical patent/IL98463A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL9846391A 1990-08-08 1991-06-12 Synergistic antimalarial compositions containing benflumetol IL98463A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN90106722A CN1058717A (zh) 1990-08-08 1990-08-08 抗疟新药—复方蒿甲醚及其制备方法
CN91102575A CN1085527C (zh) 1990-08-08 1991-04-24 增效复方抗疟药本芴醇的制备方法

Publications (2)

Publication Number Publication Date
IL98463A0 IL98463A0 (en) 1992-07-15
IL98463A true IL98463A (en) 1995-10-31

Family

ID=25742651

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9846391A IL98463A (en) 1990-08-08 1991-06-12 Synergistic antimalarial compositions containing benflumetol

Country Status (27)

Country Link
US (1) US5677331A (fr)
EP (1) EP0500823B1 (fr)
JP (1) JP2562857B2 (fr)
KR (1) KR100221689B1 (fr)
CN (2) CN1058717A (fr)
AP (1) AP231A (fr)
AT (1) ATE135209T1 (fr)
AU (1) AU642747B2 (fr)
CA (1) CA2065285C (fr)
DE (2) DE69117922T2 (fr)
DK (1) DK0500823T3 (fr)
EG (1) EG19905A (fr)
ES (1) ES2084168T3 (fr)
FI (1) FI921491L (fr)
GR (1) GR3019313T3 (fr)
HK (1) HK1000312A1 (fr)
HU (1) HU227345B1 (fr)
IE (1) IE72095B1 (fr)
IL (1) IL98463A (fr)
LU (1) LU90844I2 (fr)
MA (1) MA22176A1 (fr)
NL (1) NL300048I2 (fr)
NZ (1) NZ238477A (fr)
PT (1) PT97945B (fr)
SA (1) SA91120263B1 (fr)
WO (1) WO1992002217A1 (fr)
ZA (1) ZA914490B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637594A (en) * 1991-04-11 1997-06-10 Ciba Geigy Corporation Antimalarial synergistic compositions containing benflumetol
CA2105773A1 (fr) * 1992-02-07 1993-08-08 Anton Alexander Poltera Compositions antipaludiques synergiques contenant du benflumetol
AU2291195A (en) * 1994-04-12 1995-10-30 Qualcomm Incorporated Method and apparatus for freight transportation using a satellite navigation system
US5657088A (en) * 1995-12-22 1997-08-12 Cirrus Logic, Inc. System and method for extracting caption teletext information from a video signal
US6136847A (en) * 1996-12-02 2000-10-24 Johns Hopkins University Water-soluble trioxanes as potent and safe antimalarial agents
CH692321A5 (de) 1997-11-03 2002-05-15 Mepha Ag Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält.
CO5040050A1 (es) 1998-06-25 2001-05-29 Novartis Ag Compuestos de 2-amino-1-(9-arilmetilidina-2,7-dicloro-9h- fluoren-4-ilo)-etanoles n-sustituidos, procedimientos para su obtencion y preparados farmaceuticos que los contienen .
IN191696B (fr) 1999-02-12 2003-12-20 Council Scient Ind Res
AU2000255631A1 (en) * 2000-03-31 2001-10-15 Council Of Scientific And Industrial Research A synergistic anti-malarial formulation
EP1329452A1 (fr) * 2000-10-20 2003-07-23 Ajinomoto Co., Inc. Compositions medicamenteuses, dose et procede de traitement du paludisme
US7842719B2 (en) * 2002-10-31 2010-11-30 Kemin Foods, L.C. Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus
WO2004075817A2 (fr) * 2003-02-26 2004-09-10 Vrije Universiteit Brussel Composition pharmaceutique pouvant etre mise en suspension
WO2005023304A2 (fr) * 2003-09-04 2005-03-17 Cipla Limited Compositions antipaludeennes et procede associe
US20110206636A1 (en) * 2003-09-16 2011-08-25 Kemin Foods, LLC Use of Endoperoxides for the Treatment of Infections Caused by Flaviviridae, Including Hepatitis C, Bovine Viral Diarrhea and Classical Swine Fever Virus
WO2007017646A2 (fr) * 2005-08-05 2007-02-15 Cipla Limited Composition antimalarienne
WO2007036947A1 (fr) * 2005-09-30 2007-04-05 Ipca Laboratories Limited Composition anti-paludéenne à libération retardée
US20090324715A1 (en) * 2006-06-26 2009-12-31 Sumit Madan High dose oral pharmaceutical compositions of artemether and lumefantrine
CN100463669C (zh) * 2006-08-31 2009-02-25 广州市医药工业研究所 复方蒿甲醚自乳化剂
WO2008098586A1 (fr) * 2007-02-13 2008-08-21 Dafra Pharma N.V. Composition de support pharmaceutique et composition pharmaceutique
CH700941B1 (de) * 2007-12-04 2010-11-15 Mepha Ag Pharmazeutische Zusammensetzung zur Behandlung von Malaria.
FR2926993B1 (fr) * 2008-02-06 2011-03-11 Sanofi Aventis Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artemisinine ou l'un de ses derives pour le traitement du paludisme
WO2010004573A1 (fr) * 2008-07-07 2010-01-14 Ipca Laboratories Limited Composition pharmaceutique synergiste antipaludique
EA025956B1 (ru) * 2012-03-30 2017-02-28 Зюдцукер Акциенгезелльшафт Маннхайм/Окзенфурт Порошкообразная присыпка для нанесения на поверхность материала ядра жевательной резинки
CN103251584A (zh) * 2013-05-09 2013-08-21 西安力邦制药有限公司 注射用蒿甲醚/本芴醇复方脂肪乳的制备及其在疟疾治疗中的应用
WO2015140709A1 (fr) * 2014-03-19 2015-09-24 Novartis Ag Formes posologiques pharmaceutiques solides
WO2018198021A1 (fr) 2017-04-24 2018-11-01 Novartis Ag Régime thérapeutique de 2-amino-l-(2-(4-fluorophényl)-3-(4-fluorophénylamino) -8,8-diméthyl-5,6-dihydroimidazo[1,2-a] pyrazin-7(8h)-yl)éthanone et leurs combinaisons
CN113599382B (zh) * 2021-08-20 2023-01-03 兰州大学 喹啉类衍生物在制备治疗糖尿病及其并发症药物中的应用
CN116410197A (zh) * 2023-03-03 2023-07-11 五邑大学 一种喹啉环内过氧桥环衍生物及其制备方法
CN116747218B (zh) * 2023-08-21 2023-10-31 山东省中医药研究院 百秋李醇、百秋李醇复合抗疟组合物及制备抗疟原虫药物中的应用
LU506390B1 (en) 2024-02-09 2025-08-11 L2R Sas Oil-in-water jellified emulsion for use in anti-malarial treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85100781B (zh) * 1985-04-01 1988-07-06 广西壮族自治区桂林制药厂 抗疟药物青蒿酯的制备方法
CN85100978A (zh) * 1985-04-01 1986-08-13 中医研究院中药研究所 还原青蒿素的生产工艺
CN87101346A (zh) * 1987-06-09 1988-03-09 山东省中医药研究所 青蒿素提取工艺
EP0362810B1 (fr) * 1988-10-07 1993-05-05 Hoechst Aktiengesellschaft Compositions contre la malaria et méthodes de traitement utilisant la quinidine, artémisinine ou leurs dérivés
CN1029680C (zh) * 1988-11-10 1995-09-06 军事医学科学院微生物流行病研究所 抗疟新药苯芴醇的合成新工艺

Also Published As

Publication number Publication date
SA91120263B1 (ar) 2004-08-31
IE911989A1 (en) 1992-02-12
HUT61664A (en) 1993-03-01
KR920702217A (ko) 1992-09-03
EP0500823A1 (fr) 1992-09-02
WO1992002217A1 (fr) 1992-02-20
AU7954991A (en) 1992-03-02
EG19905A (en) 1996-05-31
KR100221689B1 (ko) 1999-09-15
US5677331A (en) 1997-10-14
CN1085527C (zh) 2002-05-29
DE69117922D1 (de) 1996-04-18
NL300048I2 (nl) 2002-03-01
HU227345B1 (en) 2011-04-28
NZ238477A (en) 1992-12-23
PT97945A (pt) 1992-04-30
CN1065993A (zh) 1992-11-11
ZA914490B (en) 1992-03-25
ATE135209T1 (de) 1996-03-15
PT97945B (pt) 1998-11-30
MA22176A1 (fr) 1991-12-31
AP231A (en) 1993-01-31
CA2065285A1 (fr) 1992-02-09
DK0500823T3 (da) 1996-04-01
EP0500823B1 (fr) 1996-03-13
HK1000312A1 (en) 1998-02-27
NL300048I1 (nl) 2001-10-01
HU9201528D0 (en) 1992-08-28
DE10199038I1 (de) 2001-11-22
FI921491A7 (fi) 1992-04-03
DE69117922T2 (de) 1996-09-05
FI921491A0 (fi) 1992-04-03
AU642747B2 (en) 1993-10-28
CN1058717A (zh) 1992-02-19
ES2084168T3 (es) 1996-05-01
LU90844I2 (fr) 2002-01-24
IL98463A0 (en) 1992-07-15
IE72095B1 (en) 1997-03-12
GR3019313T3 (en) 1996-06-30
JP2562857B2 (ja) 1996-12-11
FI921491L (fi) 1992-04-03
AP9100275A0 (en) 1991-07-31
JPH05501568A (ja) 1993-03-25
DE10199038I2 (de) 2007-01-04
CA2065285C (fr) 2000-05-09

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