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IL83691A - Acylated quinolinamines, their preparation and pharmaceutical compositions containing them - Google Patents

Acylated quinolinamines, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL83691A
IL83691A IL83691A IL8369187A IL83691A IL 83691 A IL83691 A IL 83691A IL 83691 A IL83691 A IL 83691A IL 8369187 A IL8369187 A IL 8369187A IL 83691 A IL83691 A IL 83691A
Authority
IL
Israel
Prior art keywords
6alkyl
phenyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL83691A
Other languages
English (en)
Inventor
John Ife Robert
Henry Brown Thomas
Andrew Leach Colin
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL83691A publication Critical patent/IL83691A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IL83691A 1986-09-05 1987-08-31 Acylated quinolinamines, their preparation and pharmaceutical compositions containing them IL83691A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868621425A GB8621425D0 (en) 1986-09-05 1986-09-05 Compounds

Publications (1)

Publication Number Publication Date
IL83691A true IL83691A (en) 1993-08-18

Family

ID=10603729

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83691A IL83691A (en) 1986-09-05 1987-08-31 Acylated quinolinamines, their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (2) US4806549A (fr)
EP (1) EP0259174B1 (fr)
JP (1) JPH07602B2 (fr)
KR (1) KR950013850B1 (fr)
CN (1) CN1019802B (fr)
AT (1) ATE73776T1 (fr)
AU (1) AU598299B2 (fr)
CA (1) CA1308106C (fr)
CZ (1) CZ398291A3 (fr)
DE (1) DE3777505D1 (fr)
DK (1) DK159308C (fr)
EG (1) EG18408A (fr)
ES (1) ES2033316T3 (fr)
FI (1) FI88919C (fr)
GB (1) GB8621425D0 (fr)
GR (1) GR3004692T3 (fr)
HU (1) HU199804B (fr)
IE (1) IE61104B1 (fr)
IL (1) IL83691A (fr)
MX (1) MX9203550A (fr)
MY (1) MY102689A (fr)
NO (1) NO172388C (fr)
NZ (1) NZ221663A (fr)
PH (1) PH23695A (fr)
PT (1) PT85651B (fr)
WO (1) WO1988001621A1 (fr)
ZA (1) ZA876581B (fr)
ZW (1) ZW16787A1 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
CA2011086A1 (fr) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, leur utilisation et medicaments les contenant
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
KR920701162A (ko) * 1990-03-28 1992-08-11 오츠카 아끼히코 퀴놀린 유도체, 당해 유도체를 함유하는 항궤양제 및 당해 유도체의 제조방법
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
SE9302005D0 (sv) 1993-06-11 1993-06-11 Ab Astra New active compounds
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
IN188411B (fr) * 1997-03-27 2002-09-21 Yuhan Corp
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
EP1453493A2 (fr) * 2001-11-19 2004-09-08 ALTANA Pharma AG Inhibiteurs reversibles de la pompe a protons pour le traitement des troubles des voies aeriennes
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
HRP20041160A2 (en) * 2002-05-07 2005-08-31 Altana Pharma Ag Novel combination for the treatment of airway disorders
EP1534278A4 (fr) * 2002-08-01 2006-09-06 Nitromed Inc Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation
PL1606261T3 (pl) 2003-03-10 2010-04-30 Astrazeneca Ab Nowy sposób przygotowania roflumilastu
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
WO2006097456A1 (fr) * 2005-03-16 2006-09-21 Nycomed Gmbh Forme posologique a gout masque
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
JP5474541B2 (ja) 2006-07-25 2014-04-16 ベクタ・リミテッド 小さいジカルボン酸の誘導体と組み合わせてｐｐｉを用いる胃酸分泌を阻害する組成物および方法
EP2086543A2 (fr) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprenant des agents d'inhibition de la pompe à protons labiles d'acide, au moins un autre agent pharmaceutiquement actif et leurs procédés d'utilisation
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
CA2716367C (fr) 2008-02-20 2015-05-26 The Curators Of The University Of Missouri Composition comprenant une combinaison d'omeprazole et de lansoprazole, et un agent tampon, et ses methodes d'utilisation
CN102089286A (zh) * 2008-05-07 2011-06-08 阿斯利康(瑞典)有限公司 化合物
US8247280B2 (en) 2009-10-20 2012-08-21 Taiwan Semiconductor Manufacturing Company, Ltd. Integration of low and high voltage CMOS devices
US12171755B2 (en) * 2017-10-25 2024-12-24 Children's Medical Center Corporation PAPD5 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
EP0193329A3 (fr) * 1985-02-22 1987-08-19 Beecham Group Plc Pyrazolopyridines, leur préparation et compositions pharmaceutiques les contenant
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
NO172388C (no) 1993-07-14
CN87106163A (zh) 1988-03-16
JPH07602B2 (ja) 1995-01-11
PT85651B (pt) 1990-05-31
NO172388B (no) 1993-04-05
MY102689A (en) 1992-09-30
ZA876581B (en) 1989-04-26
FI882089A0 (fi) 1988-05-04
HUT47913A (en) 1989-04-28
JPH01500664A (ja) 1989-03-09
DK245888A (da) 1988-05-05
WO1988001621A1 (fr) 1988-03-10
GR3004692T3 (fr) 1993-04-28
ES2033316T3 (es) 1993-03-16
DE3777505D1 (de) 1992-04-23
NO881940L (no) 1988-05-04
EP0259174B1 (fr) 1992-03-18
EG18408A (en) 1993-02-28
DK245888D0 (da) 1988-05-05
HU199804B (en) 1990-03-28
IE61104B1 (en) 1994-10-05
GB8621425D0 (en) 1986-10-15
MX9203550A (es) 1992-09-01
ATE73776T1 (de) 1992-04-15
EP0259174A1 (fr) 1988-03-09
DK159308B (da) 1990-10-01
AU7874187A (en) 1988-03-24
KR880701711A (ko) 1988-11-04
ZW16787A1 (en) 1988-05-25
KR950013850B1 (ko) 1995-11-17
CA1308106C (fr) 1992-09-29
PT85651A (en) 1987-10-01
NO881940D0 (no) 1988-05-04
AU598299B2 (en) 1990-06-21
FI882089A7 (fi) 1988-05-04
US4806549A (en) 1989-02-21
CZ398291A3 (en) 1994-02-16
FI88919B (fi) 1993-04-15
FI88919C (fi) 1993-07-26
US4806550A (en) 1989-02-21
IE872370L (en) 1988-03-05
PH23695A (en) 1989-09-27
DK159308C (da) 1991-03-11
CN1019802B (zh) 1992-12-30
NZ221663A (en) 1989-08-29

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Legal Events

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