IL81201A - Indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Indole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL81201A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; indole derivatives; indole
Prior art date: 1986-01-08

Application number

IL81201A

Other languages

English (en)

Other versions

IL81201A0 (en

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-08

Filing date

1987-01-08

Publication date

1991-06-10

1987-01-08 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1987-08-31 Publication of IL81201A0 publication Critical patent/IL81201A0/xx

1991-06-10 Publication of IL81201A publication Critical patent/IL81201A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL81201A 1986-01-08 1987-01-08 Indole derivatives,their preparation and pharmaceutical compositions containing them IL81201A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868600397A GB8600397D0 (en)	1986-01-08	1986-01-08	Chemical compounds

Publications (2)

Publication Number	Publication Date
IL81201A0 IL81201A0 (en)	1987-08-31
IL81201A true IL81201A (en)	1991-06-10

Family

ID=10591074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL81201A IL81201A (en)	1986-01-08	1987-01-08	Indole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country	Link
US (1)	US4855314A (fr)
EP (1)	EP0240096A1 (fr)
JP (1)	JPS62228056A (fr)
KR (1)	KR870007116A (fr)
CN (1)	CN1030409A (fr)
AU (1)	AU597325B2 (fr)
BE (1)	BE1000071A4 (fr)
CH (1)	CH672637A5 (fr)
DE (1)	DE3700408A1 (fr)
DK (1)	DK8787A (fr)
FI (1)	FI870062A7 (fr)
FR (1)	FR2595351B1 (fr)
GB (2)	GB8600397D0 (fr)
HU (1)	HU198685B (fr)
IL (1)	IL81201A (fr)
IT (1)	IT1205849B (fr)
LU (1)	LU86732A1 (fr)
NL (1)	NL8700026A (fr)
NO (1)	NO870075L (fr)
NZ (1)	NZ218868A (fr)
PH (1)	PH24741A (fr)
PT (1)	PT84075B (fr)
ZA (1)	ZA87105B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8530507D0 (en) *	1985-12-11	1986-01-22	Glaxo Group Plc	Chemical compounds
GB8600398D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
US5225431A (en) *	1987-10-23	1993-07-06	Burroughs Wellcome Co.	Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en)	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
GB8823731D0 (en) *	1988-10-10	1988-11-16	Smith Kline French Lab	Biologically active compounds
PT97888B (pt) *	1990-06-07	1998-12-31	Zeneca Ltd	Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
RO111767B1 (ro) *	1990-10-15	1997-01-30	Pfizer	Derivati de indol, procedee si intermediari pentru prepararea acestora, compozitii farmaceutice si metoda pentru tratarea unor afectiuni
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
CA2061520C (fr) *	1991-03-27	2003-04-22	Lawrence J. Daher	Systeme de delivrance accelerant l'effet et accroissant la puissance
CA2124206C (fr) *	1991-11-25	2001-02-27	John Eugene Macor	Derives indole
TW288010B (fr) *	1992-03-05	1996-10-11	Pfizer
US6380233B1 (en)	1992-04-07	2002-04-30	Pfizer Inc	Indole derivatives as 5-HT1 agonists
WO1993020073A1 (fr)	1992-04-07	1993-10-14	Pfizer Inc.	Derives d'indole en tant qu'agonistes de 5-ht1
GB9207930D0 (en) *	1992-04-10	1992-05-27	Pfizer Ltd	Indoles
JP2544704B2 (ja) *	1992-04-10	1996-10-16	フアイザー・インコーポレイテツド	５−ｈｔ▲下１▼アゴニストとしてのアシルアミノインド―ル誘導体
GB9211277D0 (en)	1992-05-28	1992-07-15	Glaxo Group Inc	Pharmaceutical compositions
TW251284B (fr) *	1992-11-02	1995-07-11	Pfizer
FR2707639B1 (fr) *	1993-06-30	1995-10-13	Pf Medicament	Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) *	1993-08-09	1996-02-16	Pfizer	Derivados de acilaminoindol
WO1995006636A1 (fr) *	1993-08-31	1995-03-09	Pfizer Inc.	Derives de 5-arylindole
US5468768A (en) *	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en)	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
FR2749846B1 (fr) *	1996-06-17	1998-09-11	Pf Medicament	Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
DE60120421T2 (de) *	2000-08-21	2006-12-28	Pacific Corp.	Neue (thio)harnstoffverbindungen und arzneimittelkompositionen, die diese enthalten
DE60309324T2 (de)	2002-06-21	2007-05-10	Suven Life Sciences Ltd.	Tetracyclische arylcarbonyl indole mit serotoninrezeptoraffinität als arzneimittel, verfahren zu ihrer herstellung und pharmazeutische zubereitungen
CA2490254C (fr) *	2002-06-21	2011-11-01	Suven Life Sciences Limited	Nouveaux indoles tetracycliques arylsulfonyle ayant une affinite du recepteur de la serotonine et utiles comme agents therapeutiques, leur procede de preparation et compositions pharmaceutiques les contenant
CN1662538A (zh) *	2002-06-21	2005-08-31	苏文生命科学有限公司	可作为治疗剂的对血清素受体具有亲和力的芳烷基吲哚、其制备工艺及其含有该物质的药物组合物
BRPI0318799B8 (pt) *	2002-11-28	2021-05-25	Suven Life Sciences Ltd	processo para a preparação de um composto
KR100776118B1 (ko)	2002-11-28	2007-11-15	수벤 라이프 사이언시스 리미티드	엔-아릴술포닐-3-아미노알콕시인돌
EA009367B1 (ru) *	2002-12-18	2007-12-28	Сувен Лайф Сайенсиз Лимитед	ПРОИЗВОДНЫЕ 5-ТИА-5-ДИОКСО-4b-АЗАИНДЕНО[2,1-a]ИНДЕНА, ОБЛАДАЮЩИЕ АФФИННОСТЬЮ К РЕЦЕПТОРУ СЕРОТОНИНА
EP2666772B1 (fr) *	2002-12-20	2017-03-01	Basf Se	Synthèse d'amines et intermédiaires pour leur synthèse
EP2032532B8 (fr) *	2006-06-12	2015-07-01	Novartis AG	Procédé de fabrication des sels de N-hydroxy-3-[4-[[[2-(2-méthyl-1H-indol-3-yl)éthyl]amino]méthyl]phényl]-2E-2-propénamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3472870A (en) *	1966-08-29	1969-10-14	Mead Johnson & Co	Sulfonamidotryptamines
FR2334358A1 (fr) *	1975-12-12	1977-07-08	Sogeras	Nouveaux medicaments derives de l'indole
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
ZW19381A1 (en) *	1980-08-12	1983-03-09	Glaxo Group Ltd	Heterocyclic compounds
FR2488606A1 (fr) *	1980-08-12	1982-02-19	Glaxo Group Ltd	Derives indoliques, leur preparation et leurs applications en tant que medicaments
GB8332437D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332434D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Production of chemical compounds
HU196752B (en) *	1983-12-06	1989-01-30	Glaxo Group Ltd	Process for production of medical compositions containing indole-derivatives and these compounds
GB8600398D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds

1986
- 1986-01-08 GB GB868600397A patent/GB8600397D0/en active Pending
1987
- 1987-01-08 NL NL8700026A patent/NL8700026A/nl not_active Application Discontinuation
- 1987-01-08 GB GB8700382A patent/GB2185020B/en not_active Expired - Fee Related
- 1987-01-08 CH CH45/87A patent/CH672637A5/fr not_active IP Right Cessation
- 1987-01-08 LU LU86732A patent/LU86732A1/fr unknown
- 1987-01-08 PH PH34698A patent/PH24741A/en unknown
- 1987-01-08 DK DK008787A patent/DK8787A/da unknown
- 1987-01-08 FR FR878700107A patent/FR2595351B1/fr not_active Expired - Fee Related
- 1987-01-08 AU AU67420/87A patent/AU597325B2/en not_active Ceased
- 1987-01-08 IL IL81201A patent/IL81201A/xx unknown
- 1987-01-08 PT PT84075A patent/PT84075B/pt not_active IP Right Cessation
- 1987-01-08 JP JP62002589A patent/JPS62228056A/ja active Pending
- 1987-01-08 EP EP87300166A patent/EP0240096A1/fr not_active Withdrawn
- 1987-01-08 NO NO870075A patent/NO870075L/no unknown
- 1987-01-08 KR KR870000068A patent/KR870007116A/ko not_active Withdrawn
- 1987-01-08 NZ NZ218868A patent/NZ218868A/xx unknown
- 1987-01-08 DE DE19873700408 patent/DE3700408A1/de not_active Withdrawn
- 1987-01-08 BE BE8700003A patent/BE1000071A4/fr not_active IP Right Cessation
- 1987-01-08 US US07/001,469 patent/US4855314A/en not_active Expired - Lifetime
- 1987-01-08 ZA ZA87105A patent/ZA87105B/xx unknown
- 1987-01-08 FI FI870062A patent/FI870062A7/fi not_active Application Discontinuation
- 1987-01-08 IT IT47507/87A patent/IT1205849B/it active
- 1987-07-03 HU HU873020A patent/HU198685B/hu not_active IP Right Cessation
- 1987-07-06 CN CN87105335A patent/CN1030409A/zh active Pending

Also Published As

Publication number	Publication date
DK8787A (da)	1987-07-09
US4855314A (en)	1989-08-08
DE3700408A1 (de)	1987-07-09
IT8747507A0 (it)	1987-01-08
NL8700026A (nl)	1987-08-03
IT1205849B (it)	1989-03-31
KR870007116A (ko)	1987-08-14
IL81201A0 (en)	1987-08-31
NO870075D0 (no)	1987-01-08
AU597325B2 (en)	1990-05-31
NO870075L (no)	1987-07-09
HU198685B (en)	1989-11-28
FR2595351B1 (fr)	1990-07-13
DK8787D0 (da)	1987-01-08
LU86732A1 (fr)	1988-02-02
JPS62228056A (ja)	1987-10-06
HUT46891A (en)	1988-12-28
CN1030409A (zh)	1989-01-18
GB2185020B (en)	1990-05-16
GB2185020A (en)	1987-07-08
PT84075B (pt)	1989-07-31
GB8600397D0 (en)	1986-02-12
EP0240096A1 (fr)	1987-10-07
PT84075A (en)	1987-02-01
GB8700382D0 (en)	1987-02-11
AU6742087A (en)	1987-07-09
CH672637A5 (fr)	1989-12-15
PH24741A (en)	1990-10-01
FI870062A7 (fi)	1987-07-09
ZA87105B (en)	1987-09-30
FI870062A0 (fi)	1987-01-08
NZ218868A (en)	1990-04-26
BE1000071A4 (fr)	1988-02-02
FR2595351A1 (fr)	1987-09-11

Publication	Publication Date	Title
IL81201A0 (en)	1987-08-31	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL86877A0 (en)	1988-11-30	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL96385A0 (en)	1991-08-16	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL73756A0 (en)	1985-03-31	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL82246A0 (en)	1987-10-30	Quinoline derivatives,their preparation and pharmaceutical compositions containing them
IL80296A (en)	1990-06-10	Phenylpyridone derivatives,their preparation and pharmaceutical compositions containing them
LTIP915A (en)	1995-03-27	Catehol derivatives,methods for their preparation and pharmaceutical compositions containing them
IL89205A (en)	1993-04-04	Chloroaniline derivatives, their preparation and pharmaceutical compositions containing them
IL83432A (en)	1992-06-21	N-phenylcarboxamide derivatives,their preparation and pharmaceutical compositions containing them
IL79401A0 (en)	1986-10-31	Distamycin derivatives,their preparation and pharmaceutical compositions containing them
NZ219624A (en)	1988-11-29	Indole derivatives and pharmaceutical compositions
IL80336A (en)	1990-02-09	Indole or benzopyrazole derivatives,their preparation and pharmaceutical compositions containing them
IL84098A0 (en)	1988-03-31	Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL79402A0 (en)	1986-10-31	Poly-4-aminopyrrole-2-carboxamido derivatives,their preparation and pharmaceutical compositions containing them
IL84380A0 (en)	1988-04-29	Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL66223A0 (en)	1982-11-30	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL84554A (en)	1992-03-29	Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL84128A (en)	1992-12-01	3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
AU6741887A (en)	1987-07-09	Indole derivatives, processes for their preparation and pharmaceutical compositions containing them
ZA871766B (en)	1987-09-01	Acetamide derivatives,their preparation and pharmaceutical compositions containing them
DE3572977D1 (en)	1989-10-19	Indole derivatives, their preparation, their use as medicines and compositions containing them
IL82860A0 (en)	1987-12-20	Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL84636A0 (en)	1988-04-29	Lactam derivatives,their preparation and pharmaceutical compositions containing them
IL83753A (en)	1991-07-18	Sulphonamidoethyl derivatives,their preparation and pharmaceutical compositions containing them
IL82324A0 (en)	1987-10-30	Ergolene derivatives,their preparation and pharmaceutical compositions containing them