IL73904A - Benzoic acid derivatives and related compounds,their production and pharmaceutical compositions containing them - Google Patents
Benzoic acid derivatives and related compounds,their production and pharmaceutical compositions containing themInfo
- Publication number
- IL73904A IL73904A IL73904A IL7390484A IL73904A IL 73904 A IL73904 A IL 73904A IL 73904 A IL73904 A IL 73904A IL 7390484 A IL7390484 A IL 7390484A IL 73904 A IL73904 A IL 73904A
- Authority
- IL
- Israel
- Prior art keywords
- production
- pharmaceutical compositions
- benzoic acid
- compositions containing
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH687983 | 1983-12-23 | ||
| CH687683 | 1983-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL73904A0 IL73904A0 (en) | 1985-03-31 |
| IL73904A true IL73904A (en) | 1989-09-10 |
Family
ID=25700317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL73904A IL73904A (en) | 1983-12-23 | 1984-12-21 | Benzoic acid derivatives and related compounds,their production and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5001133A (fr) |
| AU (2) | AU586414B2 (fr) |
| BE (1) | BE901274A (fr) |
| CH (1) | CH666268A5 (fr) |
| DE (1) | DE3445377A1 (fr) |
| DK (1) | DK624784A (fr) |
| ES (1) | ES8704490A1 (fr) |
| FI (1) | FI845075A7 (fr) |
| FR (1) | FR2557110B1 (fr) |
| GB (1) | GB2152049B (fr) |
| GR (1) | GR82578B (fr) |
| HU (1) | HU193725B (fr) |
| IL (1) | IL73904A (fr) |
| IT (1) | IT1199243B (fr) |
| LU (1) | LU85687A1 (fr) |
| NL (1) | NL8403823A (fr) |
| PT (1) | PT79726A (fr) |
| SE (1) | SE8406585L (fr) |
| WO (1) | WO1985002847A1 (fr) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5122528A (en) * | 1983-12-22 | 1992-06-16 | Erbamont, Inc. | Analgesic use of benzobicyclic carboxamides |
| EP0201165B1 (fr) * | 1985-03-14 | 1994-07-20 | Beecham Group Plc | Médicaments pour le traitement de l'éméticité |
| GB8623142D0 (en) * | 1986-09-26 | 1986-10-29 | Beecham Group Plc | Compounds |
| US4937247A (en) * | 1985-04-27 | 1990-06-26 | Beecham Group P.L.C. | 1-acyl indazoles |
| GB8515845D0 (en) * | 1985-06-22 | 1985-07-24 | Beecham Group Plc | Treatment |
| GB8516083D0 (en) * | 1985-06-25 | 1985-07-31 | Glaxo Group Ltd | Heterocyclic compounds |
| GB8520616D0 (en) * | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
| GB8523211D0 (en) * | 1985-09-19 | 1985-10-23 | Beecham Group Plc | Compounds |
| US4910193A (en) * | 1985-12-16 | 1990-03-20 | Sandoz Ltd. | Treatment of gastrointestinal disorders |
| ES2053451T3 (es) * | 1986-01-07 | 1994-08-01 | Beecham Group Plc | Un procedimiento para la preparacion de un compuesto que tiene propiedades farmacologicas utiles. |
| NL8701682A (nl) * | 1986-07-30 | 1988-02-16 | Sandoz Ag | Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten. |
| AT396870B (de) * | 1986-08-07 | 1993-12-27 | Sandoz Ag | Verfahren zur herstellung einer galenischen formulierung zur nasalen verabreichung von serotoninantagonisten |
| DE3788057T2 (de) * | 1986-12-17 | 1994-03-03 | Glaxo Group Ltd | Verwendung von heterocyclischen Verbindungen zur Behandlung von Depressionen. |
| DE3751404T2 (de) * | 1986-12-17 | 1995-12-21 | Glaxo Group Ltd | Verwendung von heterocyclischen Verbindungen zur Behandlung von Bewusstseinsstörungen. |
| IE60991B1 (en) * | 1986-12-17 | 1994-09-07 | Glaxo Group Ltd | Use of ketone derivatives in the treatment of cognitive disorders |
| GB8806990D0 (en) * | 1988-03-23 | 1988-04-27 | Beecham Group Plc | Novel compounds |
| GB8701022D0 (en) * | 1987-01-19 | 1987-02-18 | Beecham Group Plc | Treatment |
| EP0287196B1 (fr) * | 1987-02-18 | 1994-11-23 | Beecham Group Plc | Dérivés de l'indole, un procédé pour leur préparation et compositions pharmaceutiques les contenant |
| DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| US5364863A (en) * | 1987-09-08 | 1994-11-15 | Eli Lilly And Company | Specific 5-HT3 antagonists |
| US4921982A (en) * | 1988-07-21 | 1990-05-01 | Eli Lilly And Company | 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists |
| US5011846A (en) * | 1988-02-23 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Medicament compositions derived from quinolizine and quinolizinone and methods of use thereof |
| ES2080727T3 (es) * | 1988-02-23 | 1996-02-16 | Merrell Pharma Inc | Uso de quinolizina y derivados de quinolizinona en la fabricacion de medicamentos. |
| GB8814277D0 (en) * | 1988-06-16 | 1988-07-20 | Glaxo Group Ltd | Chemical compounds |
| US5126343A (en) * | 1989-09-11 | 1992-06-30 | G. D. Searle & Co. | N-azabicyclo [3.3.0]octane amides of aromatic acids |
| CA2030051C (fr) * | 1989-11-17 | 2001-08-07 | Haruhiko Kikuchi | Derives indole |
| GB8928837D0 (en) * | 1989-12-21 | 1990-02-28 | Beecham Group Plc | Pharmaceuticals |
| US5140023A (en) * | 1990-04-27 | 1992-08-18 | G. D. Searle & Co. | Azatetracycle compounds |
| US5223613A (en) * | 1990-04-27 | 1993-06-29 | G. D. Searle & Co. | Azatetracycle compounds and process of preparing same |
| US5187166A (en) * | 1990-07-31 | 1993-02-16 | Nisshin Flour Milling Co., Ltd. | Azabicyclo derivatives and their use as antiemetics |
| JP3026845B2 (ja) * | 1991-02-20 | 2000-03-27 | 日清製粉株式会社 | ピペリジン誘導体 |
| GB9103862D0 (en) * | 1991-02-25 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| US5260303A (en) * | 1991-03-07 | 1993-11-09 | G. D. Searle & Co. | Imidazopyridines as serotonergic 5-HT3 antagonists |
| US5516782A (en) * | 1991-03-07 | 1996-05-14 | G. D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
| US5227377A (en) * | 1991-03-07 | 1993-07-13 | G. D. Searle & Co. | Meso-azacyclic amides of certain bicyclic carboxylic acids |
| AU1578692A (en) * | 1991-03-07 | 1992-10-06 | G.D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
| US5137893A (en) * | 1991-03-07 | 1992-08-11 | G. D. Searle & Co. | Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
| US5234921A (en) * | 1991-03-07 | 1993-08-10 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals |
| US5219850A (en) * | 1991-03-07 | 1993-06-15 | G. D. Searle & Co. | Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
| US5196547A (en) * | 1991-03-07 | 1993-03-23 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
| EP0916346A3 (fr) | 1991-09-20 | 2000-12-06 | Glaxo Group Limited | Recepteurs antagonistes NK-1 et recepteurs antagonistes 5HT3 pour le traitement des vomissements |
| US5314899A (en) * | 1992-03-03 | 1994-05-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Epibatidine and derivatives, compositions and methods of treating pain |
| US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| JP2699794B2 (ja) * | 1992-03-12 | 1998-01-19 | 三菱化学株式会社 | チエノ〔3,2−b〕ピリジン誘導体 |
| US5236931A (en) * | 1992-03-26 | 1993-08-17 | A. H. Robins Company, Incorporated | 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol |
| US5840903A (en) * | 1992-07-27 | 1998-11-24 | G. D. Searle & Co. | 4-aminomethyl-1-azaadamantane derived benzamides |
| US5354757A (en) * | 1992-12-15 | 1994-10-11 | G. D. Searle & Co. | Azanoradamantanes |
| JP3235913B2 (ja) * | 1993-07-30 | 2001-12-04 | エーザイ株式会社 | アミノ安息香酸誘導体 |
| US5530018A (en) * | 1994-02-04 | 1996-06-25 | G. D. Searle & Co. | Meso-azanoradamantanes |
| US5399562A (en) * | 1994-02-04 | 1995-03-21 | G. D. Searle & Co. | Indolones useful as serotonergic agents |
| JP2002504883A (ja) * | 1994-08-25 | 2002-02-12 | ユニーバーシティ、オブ、バージニア | コリン受容体リガンドとしての7−アザビシクロ[2.2.1]−ヘプタン及び−ヘプテン誘導体 |
| AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
| AR036041A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen |
| ATE355293T1 (de) * | 2001-09-12 | 2006-03-15 | Pharmacia & Upjohn Co Llc | Substituierte 7-aza-(2.2.1)bicycloheptane für die behandlung von krankheiten |
| US6894042B2 (en) * | 2002-02-19 | 2005-05-17 | Pharmacia & Upjohn Company | Azabicyclic compounds for the treatment of disease |
| US6858613B2 (en) * | 2002-02-19 | 2005-02-22 | Pfizer Inc. | Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease |
| MXPA05004723A (es) * | 2002-11-01 | 2005-12-05 | Pharmacia & Upjohn Co Llc | Compuestos que tienen ambas actividades del agonista alfa 7 nachr y el antagonista 5ht para el tratamiento de las enfermedades del snc. |
| EP1802623A1 (fr) * | 2004-10-12 | 2007-07-04 | Novo Nordisk A/S | Composes spiro actifs du type a- hydroxysteroide deshydrogenase de type 1 |
| AU2006310519A1 (en) * | 2005-11-01 | 2007-05-10 | High Point Pharmaceuticals, Llc | Pharmaceutical use of substituted amides |
| US20090124598A1 (en) * | 2005-11-01 | 2009-05-14 | Henrik Sune Andersen | Pharmaceutical use of substituted amides |
| US20100168083A1 (en) * | 2006-03-21 | 2010-07-01 | Soren Ebdrup | Adamantane derivatives for the treatment of the metabolic syndrome |
| WO2007115935A1 (fr) | 2006-04-07 | 2007-10-18 | High Point Pharmaceuticals, Llc | COMPOSÉS ACTIFS de 11β-HYDROXYSTÉROÏDE DÉSHYDROGÉNASE DE TYPE 1 |
| CA2655282A1 (fr) * | 2006-06-16 | 2007-12-21 | High Point Pharmaceuticals, Llc | Utilisation pharmaceutique de carboxamides de piperidine substitues |
| CA2657078A1 (fr) * | 2006-07-13 | 2008-01-17 | High Point Pharmaceuticals, Llc | Composes actifs de 11beta-hydroxysteroide deshydrogenase de type 1 |
| EP1878721A1 (fr) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamides en tant qu'inhibiteurs de la 11-beta-hydroxysteroid dehydrogenase type 1 |
| CA2675669C (fr) * | 2007-02-23 | 2015-05-26 | High Point Pharmaceuticals, Llc | Nouveaux composes |
| EP2146952A1 (fr) * | 2007-02-23 | 2010-01-27 | High Point Pharmaceuticals, LLC | N-adamantylbenzamides utiles comme inhibiteurs de 11-beta-hydroxysteroide deshydrogenase |
| WO2008101886A1 (fr) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides utilisés en tant qu'inhibiteurs de la 11-bêta-hydroxystéroïde déshydrogénase |
| WO2008101907A2 (fr) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | Nouveaux composés |
| EA200970841A1 (ru) * | 2007-03-09 | 2010-04-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Фармацевтическое применение замещенных амидов |
| EP2141990A4 (fr) * | 2007-03-28 | 2011-07-06 | High Point Pharmaceuticals Llc | Composés actifs sur 11bêta-hsd1 |
| JP2010523692A (ja) * | 2007-04-11 | 2010-07-15 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 新規合成物 |
| CA2685036A1 (fr) * | 2007-04-24 | 2008-11-06 | High Point Pharmaceuticals, Llc | Utilisation pharmaceutique d'amides substitues |
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|---|---|---|---|---|
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| NL281394A (fr) * | 1961-07-25 | |||
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| US3577440A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-amido-pyrrolidines |
| US3702324A (en) * | 1970-06-24 | 1972-11-07 | Stanford Research Inst | 3,4,5-trimethoxybenzamides of substituted anilines and of alkylpiperidines |
| GB1507462A (en) * | 1974-03-21 | 1978-04-12 | Gallardo Antonio Sa | N-heterocyclic substituted benzamides methods for their preparation and compositions containing them |
| DE2434547A1 (de) * | 1974-07-18 | 1976-01-29 | Hoechst Ag | Beta-acyloxy-crotonsaeureamid-nsulfohalogenide, verfahren zu ihrer herstellung und ihre ueberfuehrung in suesstoffe |
| US4093734A (en) * | 1975-11-03 | 1978-06-06 | Boehringer Ingelheim Gmbh | Amino-benzoic acid amides |
| DE2557341A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
| DE2557342A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
| GB1593146A (en) * | 1976-11-05 | 1981-07-15 | Beecham Group Ltd | Octahydro-quinolizinyl benzamide derivatives |
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| GB2037740B (en) * | 1978-12-21 | 1982-11-10 | Yamanouchi Pharma Co Ltd | Benzamide derivatives |
| IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
| FR2476088A2 (fr) * | 1979-01-16 | 1981-08-21 | Delalande Sa | Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique |
| NZ197356A (en) * | 1980-06-18 | 1984-05-31 | Beecham Group Ltd | Ar-alkylsulphinyl-n-(azaicycloalkyl(alkyl)) benzamides |
| FR2493848B2 (fr) * | 1980-11-07 | 1986-05-16 | Delalande Sa | Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique |
| US4470977A (en) * | 1981-06-04 | 1984-09-11 | Adria Laboratories, Inc. | Antiemetic and antipsychotic agents |
| CA1220141A (fr) * | 1981-06-13 | 1987-04-07 | John R. Fozard | Traitement de la migraine avec des derives de benzoate de tropyle |
| EP0067615B1 (fr) * | 1981-06-17 | 1986-01-08 | Beecham Group Plc | Dérivés thioalkyl d'azabicyclobenzamides, leur procédé de préparation et les compositions pharmaceutiques les contenant |
| EP0069482A1 (fr) * | 1981-06-29 | 1983-01-12 | Beecham Group Plc | Azabicycloalkylenzamides, leur procédé de préparation et les compositions pharmaceutiques les contenant |
| EP0068700A1 (fr) * | 1981-06-29 | 1983-01-05 | Beecham Group Plc | Azabicycloalkylbenzamides, leur procédé de préparation et les compositions pharmaceutiques les contenant |
| FR2514006A1 (fr) * | 1981-10-05 | 1983-04-08 | Nativelle Sa Ets | Acylamino-4 aza-1 adamantanes, procede pour leur preparation, et application en therapeutique |
| NZ203861A (en) * | 1982-04-14 | 1986-07-11 | Beecham Group Plc | Bicyclic heterocyclic compounds and pharmaceutical compositions containing such |
| BE897117A (fr) * | 1982-06-29 | 1983-12-23 | Sandoz Sa | Nouveaux derives de la piperidine leur preparation et leur utilisation comme medicaments |
| FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
| JPS5936675A (ja) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド |
| GB2131794B (en) * | 1982-12-10 | 1986-04-03 | Merrell Toraude & Co | Treatment of migraine with n-alkyl-piperidinyl benzoate derivatives |
| EP0135545A1 (fr) * | 1983-02-19 | 1985-04-03 | Beecham Group Plc | Derives anylides et benzamides d'azabicycloalkyle |
| WO1985001048A1 (fr) * | 1983-08-26 | 1985-03-14 | Sandoz Ag | Esters ou amides aromatiques de l'acide carbonique et de l'acide sulfonique |
| DE69331958T2 (de) * | 1992-07-10 | 2002-11-28 | E.I. Du Pont De Nemours And Co., Wilmington | Azeotropische Zusammensetzungen auf Basis von Perfluorethan und Distickstoffmonoxid |
-
1984
- 1984-12-13 FR FR8419243A patent/FR2557110B1/fr not_active Expired
- 1984-12-13 DE DE19843445377 patent/DE3445377A1/de not_active Withdrawn
- 1984-12-14 HU HU844681A patent/HU193725B/hu not_active IP Right Cessation
- 1984-12-14 CH CH3601/85A patent/CH666268A5/de not_active IP Right Cessation
- 1984-12-14 WO PCT/CH1984/000196 patent/WO1985002847A1/fr not_active Ceased
- 1984-12-14 BE BE1/11152A patent/BE901274A/fr not_active IP Right Cessation
- 1984-12-17 NL NL8403823A patent/NL8403823A/nl not_active Application Discontinuation
- 1984-12-18 LU LU85687A patent/LU85687A1/fr unknown
- 1984-12-20 GB GB08432184A patent/GB2152049B/en not_active Expired
- 1984-12-20 FI FI845075A patent/FI845075A7/fi not_active Application Discontinuation
- 1984-12-21 DK DK624784A patent/DK624784A/da not_active Application Discontinuation
- 1984-12-21 AU AU37073/84A patent/AU586414B2/en not_active Ceased
- 1984-12-21 GR GR82578A patent/GR82578B/el unknown
- 1984-12-21 SE SE8406585A patent/SE8406585L/xx not_active Application Discontinuation
- 1984-12-21 IT IT49339/84A patent/IT1199243B/it active
- 1984-12-21 PT PT79726A patent/PT79726A/pt unknown
- 1984-12-21 ES ES538958A patent/ES8704490A1/es not_active Expired
- 1984-12-21 IL IL73904A patent/IL73904A/xx unknown
-
1988
- 1988-11-04 US US07/267,062 patent/US5001133A/en not_active Expired - Fee Related
-
1989
- 1989-05-05 AU AU34090/89A patent/AU3409089A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IT1199243B (it) | 1988-12-30 |
| BE901274A (fr) | 1985-06-14 |
| SE8406585D0 (sv) | 1984-12-21 |
| WO1985002847A1 (fr) | 1985-07-04 |
| IT8449339A0 (it) | 1984-12-21 |
| FI845075L (fi) | 1985-06-24 |
| DK624784A (da) | 1985-06-24 |
| HU193725B (en) | 1987-11-30 |
| PT79726A (en) | 1985-01-01 |
| SE8406585L (sv) | 1985-06-24 |
| DE3445377A1 (de) | 1985-07-04 |
| FI845075A7 (fi) | 1985-06-24 |
| FR2557110A1 (fr) | 1985-06-28 |
| US5001133A (en) | 1991-03-19 |
| GR82578B (en) | 1985-04-23 |
| ES538958A0 (es) | 1987-04-01 |
| LU85687A1 (fr) | 1985-09-12 |
| GB2152049B (en) | 1988-06-15 |
| FR2557110B1 (fr) | 1989-11-24 |
| AU3409089A (en) | 1989-09-21 |
| HUT38341A (en) | 1986-05-28 |
| ES8704490A1 (es) | 1987-04-01 |
| GB2152049A (en) | 1985-07-31 |
| FI845075A0 (fi) | 1984-12-20 |
| DK624784D0 (da) | 1984-12-21 |
| NL8403823A (nl) | 1985-07-16 |
| GB8432184D0 (en) | 1985-01-30 |
| CH666268A5 (de) | 1988-07-15 |
| AU3707384A (en) | 1985-07-04 |
| IL73904A0 (en) | 1985-03-31 |
| AU586414B2 (en) | 1989-07-13 |
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