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IL137812A0 - Novel triazolo (4,5-d) pyrimidine compounds - Google Patents

Novel triazolo (4,5-d) pyrimidine compounds

Info

Publication number
IL137812A0
IL137812A0 IL13781299A IL13781299A IL137812A0 IL 137812 A0 IL137812 A0 IL 137812A0 IL 13781299 A IL13781299 A IL 13781299A IL 13781299 A IL13781299 A IL 13781299A IL 137812 A0 IL137812 A0 IL 137812A0
Authority
IL
Israel
Prior art keywords
pyrimidine compounds
novel triazolo
triazolo
novel
pyrimidine
Prior art date
Application number
IL13781299A
Other languages
English (en)
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9800458A external-priority patent/SE9800458D0/xx
Priority claimed from SE9803669A external-priority patent/SE9803669D0/xx
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of IL137812A0 publication Critical patent/IL137812A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL13781299A 1998-02-17 1999-02-05 Novel triazolo (4,5-d) pyrimidine compounds IL137812A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9800458A SE9800458D0 (sv) 1998-02-17 1998-02-17 Novel compounds
SE9803669A SE9803669D0 (sv) 1998-10-26 1998-10-26 Novel compounds
PCT/SE1999/000154 WO1999041254A1 (en) 1998-02-17 1999-02-05 NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS

Publications (1)

Publication Number Publication Date
IL137812A0 true IL137812A0 (en) 2001-10-31

Family

ID=26663214

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13781299A IL137812A0 (en) 1998-02-17 1999-02-05 Novel triazolo (4,5-d) pyrimidine compounds

Country Status (21)

Country Link
US (1) US6369064B1 (xx)
EP (1) EP1056749B1 (xx)
JP (1) JP2002503663A (xx)
KR (1) KR20010078696A (xx)
CN (1) CN1291193A (xx)
AR (1) AR015515A1 (xx)
AT (1) ATE232866T1 (xx)
AU (1) AU2650099A (xx)
BR (1) BR9907934A (xx)
CA (1) CA2316264A1 (xx)
DE (1) DE69905451T2 (xx)
HU (1) HUP0100328A3 (xx)
ID (1) ID27127A (xx)
IL (1) IL137812A0 (xx)
MX (1) MXPA00007634A (xx)
NO (1) NO20004089L (xx)
NZ (1) NZ505250A (xx)
PL (1) PL342430A1 (xx)
SK (1) SK12242000A3 (xx)
TR (1) TR200002380T2 (xx)
WO (1) WO1999041254A1 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702773D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9904129D0 (sv) 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
AR028110A1 (es) * 2000-06-02 2003-04-23 Astrazeneca Ab Nuevo proceso
GB0013488D0 (en) * 2000-06-02 2000-07-26 Astrazeneca Ab Chemical compound
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
GB0219746D0 (en) * 2002-08-23 2002-10-02 Inst Of Ex Botany Ascr Azapurine derivatives
US7504497B2 (en) * 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
US7749981B2 (en) 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
US7335648B2 (en) 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
EP1685135B1 (en) * 2003-10-21 2010-05-26 Inspire Pharmaceuticals, Inc. TETRAHYDRO-FURO[3,4-d]DIOXOLE COMPOUNDS AND COMPOSITIONS AND METHOD FOR INHIBITING PLATELET AGGREGATION
US7932376B2 (en) 2005-05-05 2011-04-26 Inspire Pharmaceuticals, Inc. Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation
JPWO2007020935A1 (ja) * 2005-08-17 2009-02-26 小野薬品工業株式会社 P2y12受容体および/またはp2y14受容体ブロッカーを含有してなる疼痛治療剤
US7566722B2 (en) 2006-10-31 2009-07-28 Janssen Pharmaceutica, N.V. Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists
BRPI0918038B1 (pt) * 2008-09-09 2021-07-13 Astrazeneca Ab Processo para preparar um composto
WO2015027431A1 (en) * 2013-08-29 2015-03-05 Merck Sharp & Dohme Corp. 2,2-difluorodioxolo a2a receptor antagonists
WO2015162630A1 (en) * 2014-04-25 2015-10-29 Anlon Chemical Research Organization Novel processes for preparing triazolo [4,5-d]- pyrimidines, including ticagrelor, vianew intermediates and new route of synthesis.
DK3433234T3 (da) 2016-03-22 2022-01-03 Merck Sharp & Dohme Allosteriske modulatorer af nicotinacetylcholinreceptorer
CN111116592A (zh) * 2019-11-27 2020-05-08 杭州沧海帆医药科技有限公司 嘧啶并三氮唑类化合物及其医药用途
CN112876485A (zh) * 2021-01-25 2021-06-01 郭丽伟 一种用于治疗子宫平滑肌高频率强直性收缩相关疾病的化合物
US20250017936A1 (en) * 2021-11-22 2025-01-16 Purdue Research Foundation Cell-potent bisubstrate inhibitors for nicotinamide n-methyltransferase (nnmt) and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742064A (en) 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
GB8826205D0 (en) 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
TW427996B (en) 1995-07-11 2001-04-01 Astra Pharma Prod Novel triazolopyrimidines and their use as medicaments
WO1998028300A1 (en) 1996-12-20 1998-07-02 Astra Pharmaceuticals Ltd. Triazolo[4,5-d]pyrimidinyl derivatives and their use as medicaments
SE9702772D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9702774D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds

Also Published As

Publication number Publication date
CA2316264A1 (en) 1999-08-19
EP1056749A1 (en) 2000-12-06
HUP0100328A3 (en) 2003-04-28
CN1291193A (zh) 2001-04-11
MXPA00007634A (es) 2003-09-10
JP2002503663A (ja) 2002-02-05
KR20010078696A (ko) 2001-08-21
AR015515A1 (es) 2001-05-02
AU2650099A (en) 1999-08-30
ID27127A (id) 2001-03-01
US6369064B1 (en) 2002-04-09
TR200002380T2 (tr) 2001-03-21
HUP0100328A2 (hu) 2001-09-28
DE69905451D1 (de) 2003-03-27
NO20004089L (no) 2000-10-16
BR9907934A (pt) 2000-10-24
PL342430A1 (en) 2001-06-04
NZ505250A (en) 2002-10-25
WO1999041254A1 (en) 1999-08-19
EP1056749B1 (en) 2003-02-19
NO20004089D0 (no) 2000-08-16
SK12242000A3 (sk) 2001-03-12
DE69905451T2 (de) 2003-11-20
ATE232866T1 (de) 2003-03-15

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