IE782328L - INDOLO (2,3-a) QUINOLIZIDINES - Google Patents
INDOLO (2,3-a) QUINOLIZIDINESInfo
- Publication number
- IE782328L IE782328L IE782328A IE232878A IE782328L IE 782328 L IE782328 L IE 782328L IE 782328 A IE782328 A IE 782328A IE 232878 A IE232878 A IE 232878A IE 782328 L IE782328 L IE 782328L
- Authority
- IE
- Ireland
- Prior art keywords
- indolo
- quinolizidines
- radical
- group
- methylenamido
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OURDZMSSMGUMKR-UHFFFAOYSA-N 1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine Chemical class C1=CC=C2C(CCN3CCCCC33)=C3NC2=C1 OURDZMSSMGUMKR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Abstract
New indolo (2, 3-a) quinolizidines having the following formulae (I) and (II) (FORMULA) wherein R is a radical -COOC2H5, -COOH, -CN, a primary or secondary methylenamino radical, a group methylenamido or, with the nitrogen of the indolo nucleus, a group N-CO-NH-CH2 or N-CO-, as well as the salts of acid addition, therapeutically acceptable of these bodies. Also, a process for preparing the compounds.[WO7900319A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4920177 | 1977-11-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE782328L true IE782328L (en) | 1979-05-25 |
| IE47518B1 IE47518B1 (en) | 1984-04-04 |
Family
ID=10451538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2328/78A IE47518B1 (en) | 1977-11-25 | 1978-11-24 | Indolo (2,3-a) quinolizidines,preparation and therapeutic use |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS6147838B2 (en) |
| AR (1) | AR218514A1 (en) |
| AT (1) | AT372384B (en) |
| AU (1) | AU529108B2 (en) |
| BE (1) | BE872134A (en) |
| CA (1) | CA1100959A (en) |
| CH (1) | CH641181A5 (en) |
| DE (1) | DE2851028A1 (en) |
| DK (1) | DK154430C (en) |
| EG (1) | EG13683A (en) |
| ES (1) | ES475328A1 (en) |
| FI (1) | FI64372C (en) |
| FR (2) | FR2409755A1 (en) |
| HK (1) | HK60884A (en) |
| IE (1) | IE47518B1 (en) |
| IN (1) | IN151146B (en) |
| IT (1) | IT1160263B (en) |
| LU (1) | LU80576A1 (en) |
| MX (1) | MX5529E (en) |
| MY (1) | MY8500029A (en) |
| NL (1) | NL7811562A (en) |
| NO (1) | NO151288C (en) |
| NZ (1) | NZ188974A (en) |
| PT (1) | PT68825A (en) |
| SE (2) | SE431650B (en) |
| SG (1) | SG61182G (en) |
| WO (1) | WO1979000319A1 (en) |
| ZA (1) | ZA786426B (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3175900D1 (en) * | 1981-11-18 | 1987-03-12 | Thal Claude | Indoloquinolizine derivatives, process for their preparation and their therapeutic use |
| FR2529552B1 (en) * | 1982-07-05 | 1985-09-27 | Centre Nat Rech Scient | NOVEL PROCESS FOR THE PREPARATION OF VINDOLINE SYNTHESIS INTERMEDIATES AND SYNTHESIS INTERMEDIATES |
| HU191454B (en) * | 1984-10-05 | 1987-02-27 | Richter Gedeon Vegyeszeti Gyar Rt.,Hu | Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof |
| HU195214B (en) * | 1985-04-19 | 1988-04-28 | Richter Gedeon Vegyeszet | Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds |
| HU194220B (en) * | 1985-04-19 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
| FI95572C (en) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Process for the preparation of a medicament useful as a piperidine derivative or its pharmaceutical salt |
| ES2158896T3 (en) * | 1993-06-18 | 2001-09-16 | Fujisawa Pharmaceutical Co | NEW INTERMEDIATE COMPOUND FOR USE IN SYNTHESIS AND PROCEDURE TO PRODUCE AN AMINOPIPERAZINE DERIVATIVE. |
| FR2713643B1 (en) * | 1993-12-14 | 1996-06-07 | Adir | New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them. |
| FR2713644B1 (en) * | 1993-12-14 | 1996-02-09 | Adir | New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them. |
| ATE426127T2 (en) † | 2002-06-24 | 2009-04-15 | Saint Gobain Isover | INSULATING PLATE FOR FEED DUCT |
| FR2911141B1 (en) * | 2007-01-05 | 2009-02-20 | Servier Lab | NOVEL TRIAZABENZO [A] NAPHTHO [2,1,8-CDE] AZULENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| FR2911143A1 (en) * | 2007-01-05 | 2008-07-11 | Servier Lab | Use of neuroprotective compounds to prepare medicaments for treating neurodegenerative diseases |
| FR2911142A1 (en) * | 2007-01-05 | 2008-07-11 | Servier Lab | NOVEL AMINOPYRROLO [1,2-A] INDOLE AND AMINOPYRIDAZINO [1,6-A] INDOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| USD685269S1 (en) | 2012-04-04 | 2013-07-02 | Colgate-Palmolive Company | Container |
| USD685271S1 (en) | 2012-04-04 | 2013-07-02 | Colgate-Palmolive Company | Container |
| USD688951S1 (en) | 2012-04-04 | 2013-09-03 | Colgate-Palmolive Company | Container |
| USD685270S1 (en) | 2012-04-04 | 2013-07-02 | Colgate-Palmolive Company | Container |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU167366B (en) * | 1972-09-06 | 1975-09-27 | ||
| BE802387A (en) * | 1973-07-16 | 1973-11-16 | Omnium Chimique Sa | PROCESS FOR PREPARING VINCAMONE AND EPI-21 VINCAMONE FROM TABERSONIN AND NEW INDOLIC DERIVATIVES. |
| HU169916B (en) * | 1974-09-27 | 1977-02-28 | ||
| HU171165B (en) * | 1974-11-26 | 1977-11-28 | Richter Gedeon Vegyeszet | Process for producing oktahydro-indolo-bracket-2,3-a-bracket closed-quinolizine derivatives |
| FR2315277A1 (en) * | 1975-06-25 | 1977-01-21 | Anvar | NEW PENTACYCLIC DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM |
-
1978
- 1978-11-15 ZA ZA00786426A patent/ZA786426B/en unknown
- 1978-11-20 BE BE191824A patent/BE872134A/en not_active IP Right Cessation
- 1978-11-22 NZ NZ188974A patent/NZ188974A/en unknown
- 1978-11-23 AT AT0837478A patent/AT372384B/en active
- 1978-11-23 NO NO783958A patent/NO151288C/en unknown
- 1978-11-23 AU AU41874/78A patent/AU529108B2/en not_active Expired
- 1978-11-23 FI FI783581A patent/FI64372C/en not_active IP Right Cessation
- 1978-11-23 AR AR274552A patent/AR218514A1/en active
- 1978-11-23 ES ES475328A patent/ES475328A1/en not_active Expired
- 1978-11-23 PT PT68825A patent/PT68825A/en unknown
- 1978-11-24 CH CH683579A patent/CH641181A5/en not_active IP Right Cessation
- 1978-11-24 NL NL7811562A patent/NL7811562A/en not_active Application Discontinuation
- 1978-11-24 FR FR7833176A patent/FR2409755A1/en active Granted
- 1978-11-24 MX MX787557U patent/MX5529E/en unknown
- 1978-11-24 FR FR7833175A patent/FR2423492A1/en active Granted
- 1978-11-24 WO PCT/FR1978/000043 patent/WO1979000319A1/en not_active Ceased
- 1978-11-24 DK DK524978A patent/DK154430C/en not_active IP Right Cessation
- 1978-11-24 JP JP54500118A patent/JPS6147838B2/ja not_active Expired
- 1978-11-24 IE IE2328/78A patent/IE47518B1/en unknown
- 1978-11-24 CA CA316,809A patent/CA1100959A/en not_active Expired
- 1978-11-24 IT IT30171/78A patent/IT1160263B/en active
- 1978-11-24 LU LU80576A patent/LU80576A1/en unknown
- 1978-11-24 DE DE19782851028 patent/DE2851028A1/en active Granted
- 1978-11-24 IN IN851/DEL/78A patent/IN151146B/en unknown
- 1978-11-25 EG EG669/78A patent/EG13683A/en active
-
1979
- 1979-07-23 SE SE7906287A patent/SE431650B/en not_active IP Right Cessation
-
1980
- 1980-11-07 SE SE8007845A patent/SE435622B/en not_active IP Right Cessation
-
1982
- 1982-12-03 SG SG611/82A patent/SG61182G/en unknown
-
1984
- 1984-08-02 HK HK608/84A patent/HK60884A/en unknown
-
1985
- 1985-12-30 MY MY29/85A patent/MY8500029A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE782328L (en) | INDOLO (2,3-a) QUINOLIZIDINES | |
| IE781878L (en) | Imidazole derivatives | |
| MY101891A (en) | Novel carbostyril derivative and process for preparing same. | |
| IE780605L (en) | 1, 2-DIHYDRO-3H-PYRROLO [1,2-a] PYRROLES | |
| IE800249L (en) | Heterotricyclic compounds | |
| AU4946185A (en) | Quinolonecarboxylic acid derivatives | |
| IE790878L (en) | Purine derivatives | |
| IE45141L (en) | Prostaglandin derivatives | |
| IE820239L (en) | Carbapenem derivatives | |
| IE42672L (en) | Thieno-tetrahydropyridine derivatives | |
| IE810326L (en) | Preparing flumequine. | |
| IE791277L (en) | PYRAZOLO (3,4-b) PYRIDINES | |
| IE831004L (en) | Long-acting theophylline in medicinal form | |
| ES532698A0 (en) | A PROCEDURE FOR PREPARING 1, 2, 3-TRIAZINO- (4 ', 5': 4; 5) TIENO (2, 3-B) -QUINOLIN-4 (3H) -ONAS. | |
| AU9100482A (en) | 2-phenyl morpholine derivatives | |
| IE792067L (en) | Azatricyclic compounds | |
| IE790650L (en) | Substituted n-iminomethylpiperidine | |
| JPS527994A (en) | Process for preparing novel pyrimido (4,5-d) pyrimidine derivatives | |
| JPS52116497A (en) | Fused-ring triazolopyrimidine derivatives | |
| IE42992L (en) | PYRIMIDO [1,2-a] QUINOLINE DERIVATIVES | |
| AU572147B2 (en) | Dibenzopyran derivatives | |
| HK66283A (en) | New 16-methoxy-16-methyl prostaglandin e1 derivatives, a process for preparing them and their use as gastroprotective agents | |
| JPS5283732A (en) | Haloazetidinone compounds | |
| ES8705454A1 (en) | Imidazoalkylcarboxylic-acid derivatives, process for their preparation and their use in the preparation of pharmaceutically active compounds. | |
| JPS5430167A (en) | 4-aminomethyl-2-phenyloxazoles and their pharmaceutically acceptable acid salts |