ID30115A - Komposisi eplerenon yang dimikronisasi - Google Patents
Komposisi eplerenon yang dimikronisasiInfo
- Publication number
- ID30115A ID30115A IDW00200101191A ID20011191A ID30115A ID 30115 A ID30115 A ID 30115A ID W00200101191 A IDW00200101191 A ID W00200101191A ID 20011191 A ID20011191 A ID 20011191A ID 30115 A ID30115 A ID 30115A
- Authority
- ID
- Indonesia
- Prior art keywords
- micronized eplerenone
- composition
- eplerenone composition
- micronized
- eplerenone
- Prior art date
Links
- JUKPWJGBANNWMW-VWBFHTRKSA-N eplerenone Chemical compound C([C@@H]1[C@]2(C)C[C@H]3O[C@]33[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)C(=O)OC)C[C@@]21CCC(=O)O1 JUKPWJGBANNWMW-VWBFHTRKSA-N 0.000 title 1
- 229960001208 eplerenone Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11164698P | 1998-12-09 | 1998-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID30115A true ID30115A (id) | 2001-11-08 |
Family
ID=22339668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW00200101191A ID30115A (id) | 1998-12-09 | 1999-12-08 | Komposisi eplerenon yang dimikronisasi |
Country Status (30)
| Country | Link |
|---|---|
| US (7) | US6410054B1 (fr) |
| EP (1) | EP1135139B1 (fr) |
| JP (1) | JP2002531508A (fr) |
| KR (1) | KR100671275B1 (fr) |
| CN (1) | CN1230179C (fr) |
| AR (1) | AR028982A1 (fr) |
| AT (1) | ATE249223T1 (fr) |
| AU (1) | AU763166B2 (fr) |
| BR (1) | BR9915964A (fr) |
| CA (1) | CA2326842A1 (fr) |
| CZ (1) | CZ20011942A3 (fr) |
| DE (1) | DE69911240T2 (fr) |
| DK (1) | DK1135139T3 (fr) |
| EA (1) | EA003266B1 (fr) |
| ES (1) | ES2207977T3 (fr) |
| HK (1) | HK1041641B (fr) |
| HU (1) | HU224428B1 (fr) |
| ID (1) | ID30115A (fr) |
| IL (1) | IL143301A0 (fr) |
| IS (1) | IS2325B (fr) |
| MY (1) | MY125651A (fr) |
| NO (1) | NO20012782L (fr) |
| NZ (1) | NZ511869A (fr) |
| PL (1) | PL198425B1 (fr) |
| PT (1) | PT1135139E (fr) |
| TR (1) | TR200101643T2 (fr) |
| TW (1) | TWI234459B (fr) |
| UA (1) | UA74141C2 (fr) |
| WO (1) | WO2000033847A1 (fr) |
| ZA (1) | ZA200104361B (fr) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| EP1527782A1 (fr) * | 1999-12-08 | 2005-05-04 | Pharmacia Corporation | Compositions nanoparticulaires d'eplérenone |
| DK1175220T3 (da) * | 1999-12-08 | 2005-08-29 | Pharmacia Corp | Nanopartikulære eplerenonkompositioner |
| JP2004501099A (ja) * | 2000-05-11 | 2004-01-15 | フアルマシア コーポレイション | アルドステロン頂点位相時の放出のためのアルドステロンアンタゴニスト組成物 |
| ES2265437T3 (es) * | 2000-07-27 | 2007-02-16 | Pharmacia Corporation | Terapia de combinacion antagonista epoxi-esteroidal de aldosterona y antagonista beta-adrenergico para tratamiento de la insuficiencia cardiaca congestiva. |
| JP2004518611A (ja) * | 2000-07-27 | 2004-06-24 | ファルマシア・コーポレーション | 炎症関連障害を予防するか又は治療するためのアルドステロン遮断薬療法 |
| AU2001285318A1 (en) * | 2000-08-28 | 2002-03-13 | Pharmacia Corporation | Use of an aldosterone receptor antagonist to improve cognitive function |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| US7138390B2 (en) | 2001-03-12 | 2006-11-21 | Intercept Pharmaceuticals | Steroids as agonists for FXR |
| US20040173147A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| US6962715B2 (en) * | 2001-10-24 | 2005-11-08 | Hewlett-Packard Development Company, L.P. | Method and dosage form for dispensing a bioactive substance |
| US20040173146A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| GB0114532D0 (en) * | 2001-06-14 | 2001-08-08 | Jagotec Ag | Novel compositions |
| UA76475C2 (en) * | 2001-07-19 | 2006-08-15 | Pharmacia Corp | Combination of eplerenon and hmg co-a reductase inhibitor and its use for treatment and/or prophylaxis of pathologic condition in cardiovascular system |
| IL162393A0 (en) * | 2001-12-13 | 2005-11-20 | Pharmacia Corp | Methods for treatment or prophylaxis of aldosterone-mediated pathogenic effects in a subject using an epoxy-steroidal aldosteron |
| EP1469884A1 (fr) * | 2002-01-30 | 2004-10-27 | Pharmacia Corporation | Therapie combinant un antagoniste d'aldosterone et un agent anti-inflammatoire et destinee a prevenir ou a traiter les troubles cardio-vasculaires |
| KR101002374B1 (ko) * | 2002-02-26 | 2010-12-17 | 아스트라제네카 아베 | 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물 |
| US20040072797A1 (en) * | 2002-03-20 | 2004-04-15 | Pornanong Aramwit | Storage stable eplerenone formulation |
| US7235655B2 (en) * | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
| HRP20041121A2 (en) * | 2002-04-26 | 2005-02-28 | Schering Aktiengesellschaft | Treatment of hypertension in women receiving hormone replacement therapy |
| JP2005536536A (ja) * | 2002-08-23 | 2005-12-02 | ファルマシア コーポレイション | アルドステロンブロッカーによるマトリックスメタロプロテイナーゼ(mmp)活性のモジュレーション |
| CN1694689A (zh) * | 2002-09-30 | 2005-11-09 | 阿库斯菲尔公司 | 供吸入的缓释多孔微粒 |
| AU2002368326A1 (en) * | 2002-11-05 | 2004-06-07 | Schering Aktiengesellschaft | Hormone replacement therapy with drospirenone |
| US7786101B2 (en) * | 2002-11-05 | 2010-08-31 | Bayer Schering Pharma Ag | Cardiovascular protection using anti-aldosteronic progestins |
| DE60330888D1 (de) * | 2002-11-05 | 2010-02-25 | Bayer Schering Pharma Ag | Verwendung von drospirenon zur behandlung von hypertension |
| JP2006511525A (ja) * | 2002-12-13 | 2006-04-06 | ヤゴテック アーゲー | ナノ粒子状スピロノラクトン局所製剤 |
| DE10335027A1 (de) | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
| CA2522971A1 (fr) * | 2003-04-25 | 2004-11-11 | Novacardia, Inc. | Methode pour ameliorer la diurese chez des personnes a fonction renale alteree |
| US20060293312A1 (en) * | 2003-04-25 | 2006-12-28 | Howard Dittrich | Method of improved diuresis in individuals with impaired renal function |
| KR100473422B1 (ko) * | 2003-06-12 | 2005-03-14 | 박원봉 | 렉틴 함유 천연물의 장용성 코팅용 조성물 |
| CA2529746C (fr) * | 2003-06-16 | 2010-08-03 | Andrx Pharmaceuticals, Llc | Composition orale a liberation prolongee |
| US7198653B2 (en) | 2003-07-31 | 2007-04-03 | Delavau Llc | Calcium carbonate granulation |
| US20050031683A1 (en) * | 2003-08-04 | 2005-02-10 | Ashish Kapoor | Solid pharmaceutical composition |
| US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
| US7282217B1 (en) * | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
| US7829595B2 (en) * | 2003-09-12 | 2010-11-09 | Amgen Inc. | Rapid dissolution formulation of a calcium receptor-active compound |
| CA2533887A1 (fr) * | 2003-09-30 | 2005-04-14 | Acusphere, Inc. | Formulations pharmaceutiques a effet prolonge, administrees par injection, par voie orale ou topique |
| US20050203482A1 (en) * | 2004-03-15 | 2005-09-15 | Chinea Vanessa I. | Pharmaceutical dispensing apparatus and method |
| US20070196471A1 (en) * | 2004-04-02 | 2007-08-23 | Thosar Shilpa S | Micronized Eplerenone Compositions |
| US20050232957A1 (en) * | 2004-04-14 | 2005-10-20 | Katz Kenneth A | Compositions and methods for moisturizing skin |
| MXPA06011823A (es) * | 2004-04-16 | 2006-12-15 | Novacardia Inc | Terapia de combinacion, que comprende un antagonista del receptor de la adenosina a1 y un inhibidor de la aldosterona. |
| US8075910B2 (en) * | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
| US7846466B2 (en) * | 2004-06-10 | 2010-12-07 | Northwestern University | Biodegradable scaffolds and uses thereof |
| US20060134212A1 (en) * | 2004-09-02 | 2006-06-22 | Forest Laboratories, Inc. | Lercanidipine immediate release compositions |
| US20060165788A1 (en) * | 2004-09-09 | 2006-07-27 | Wattanaporn Abramowitz | Lercanidipine pH dependent pulsatile release compositions |
| US20060165789A1 (en) * | 2004-09-09 | 2006-07-27 | Forest Laboratories, Inc. | Lercanidipine modified release compositions |
| US8022053B2 (en) * | 2004-11-02 | 2011-09-20 | Bayer Schering Pharma Aktiengesellschaft | Oral solid dosage forms containing a low dose of estradiol |
| EP1701722B1 (fr) * | 2004-11-23 | 2009-10-14 | Dong Wha Pharmaceutical Co., Ltd. | Sel d'acide n-hydroxy-4-}5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy]pentoxy}benzamidine 2 methanesulfonique |
| WO2006097342A1 (fr) * | 2005-03-17 | 2006-09-21 | Synthon B.V. | Procede de preparation de composes steroides |
| US20060252738A1 (en) * | 2005-05-06 | 2006-11-09 | Phero Tech Inc. | Method for preparing and using water-based steroid pheromone compositions |
| WO2006125304A1 (fr) * | 2005-05-25 | 2006-11-30 | Liponex, Inc. | Compositions pharmaceutiques pour traiter ou prevenir une maladie coronarienne |
| WO2007012960A1 (fr) * | 2005-07-29 | 2007-02-01 | Glenmark Pharmaceuticals Limited | Compositions pharmaceutiques à base d’éplérénone |
| US20070095705A1 (en) * | 2005-10-31 | 2007-05-03 | Legault Dennis X | Array of packages |
| BRPI0706575B8 (pt) * | 2006-01-13 | 2021-05-25 | Univ Indiana Res & Tech Corp | uso colágeno de tipo v ou um componente antigênico do mesmo, e, método para identificar um paciente em espera de transplante de pulmão para um risco aumentado de rejeição de tecido de órgão transplantado. |
| US20070184163A1 (en) * | 2006-02-07 | 2007-08-09 | International Flavors, & Fragrances Inc. | Non-hygroscopic flavor particles |
| WO2007102169A1 (fr) * | 2006-03-08 | 2007-09-13 | Jubilant Organosys Limited | Préparation pharmaceutique de venlafaxine à libération prolongée et son procédé de fabrication |
| US20070248665A1 (en) * | 2006-04-24 | 2007-10-25 | Sherman Bernard C | Compositions comprising co-precipitate of eplerenone and a water-soluble excipient |
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| US9138414B1 (en) | 2006-09-15 | 2015-09-22 | Delavau Llc | Calcium supplement having enhanced absorption |
| US20100086586A1 (en) * | 2006-12-21 | 2010-04-08 | Brett Antony Mooney | Pharmaceutical Composition |
| US20100137424A1 (en) * | 2007-01-22 | 2010-06-03 | Mostafa Akbarieh | Pharmaceutical compositions comprising nebivolol or a nebivolol analogue |
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| US8372431B2 (en) | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
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| DK2470165T3 (en) * | 2009-08-28 | 2018-06-06 | Hercules Llc | FILM COATING COMPOSITION OF SOLID POWDER COMPOUNDS |
| US9345848B2 (en) | 2009-10-20 | 2016-05-24 | Sima Patent Ve Lisanslama Hizmetleri Ltd. Sti. | Dry powder inhaler |
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| ES2550033T3 (es) | 2009-12-23 | 2015-11-04 | Ratiopharm Gmbh | Forma de dosificación farmacéutica sólida de ticagrelor |
| UY33455A (es) * | 2010-06-16 | 2012-01-31 | Teijin Pharma Ltd | Tableta con núcleo recubierto de liberación controlada |
| TR201007653A2 (tr) * | 2010-09-20 | 2012-04-24 | Bi̇lgi̇ç Mahmut | Eplerenon içeren farmasötik kompozisyon |
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| US9849255B2 (en) | 2011-11-25 | 2017-12-26 | Mahmut Bilgic | Inhalation device |
| EP2875359A4 (fr) | 2012-03-30 | 2015-08-19 | Charles R Drew University Of Medicine And Science | Compositions et procédés de traitement ou de prévention de troubles du syndrome métabolique |
| EA201492082A1 (ru) | 2012-06-04 | 2015-03-31 | Фармасайкликс, Инк. | Кристаллические формы ингибитора тирозинкиназы брутона |
| FR3001890B1 (fr) * | 2013-02-08 | 2015-08-07 | Greenpharma Sas | Composition dermatologique pour repousse des poils ou des cheveux |
| US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
| USD744087S1 (en) | 2013-10-01 | 2015-11-24 | Mahmut Bilgic | Dry powder inhaler |
| US11007203B2 (en) * | 2013-10-06 | 2021-05-18 | Salim Shah | Formulations comprising aldosterone receptor antagonists and treatments using same |
| WO2015089416A1 (fr) | 2013-12-12 | 2015-06-18 | Cornell University | Inhibiteurs de la prolylhydroxylase/atf4 pour le traitement des lésions cellulaires neuronales |
| FR3019045A1 (fr) * | 2014-03-26 | 2015-10-02 | Greenpharma Sas | Composition dermatologique pour la repousse des poils ou des cheveux |
| EP3193877A4 (fr) | 2014-08-07 | 2018-04-04 | Pharmacyclics LLC | Nouvelles formulations d'un inhibiteur de la tyrosine kinase de bruton |
| WO2016063269A1 (fr) | 2014-10-20 | 2016-04-28 | Prendergast Patrick T | Utilisation d'antagonistes au récepteur stéroïdien nucléaire, seuls ou en association, comme agents antiviraux directs pour inhiber des alphavirus, togavirus, filovirus, arénavirus, bunyavirus, flavivirus et rhabdovirus |
| US9931344B2 (en) | 2015-01-12 | 2018-04-03 | Nano Pharmaceutical Laboratories, Llc | Layered sustained-release microbeads and methods of making the same |
| IL315294A (en) | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of bruton's tyrosine kinase inhibitor |
| GB201913972D0 (en) * | 2019-09-27 | 2019-11-13 | Univ Ulster | Pharmaceutical Delivery Device and method of manufacture |
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| IT1130924B (it) * | 1980-03-06 | 1986-06-18 | Secifarma Spa | Procedimento per la preparazione di spironolattone micronizzato |
| FI77669C (fi) * | 1983-04-13 | 1989-04-10 | Ciba Geigy Ag | 20-spiroxaner och analoger, som innehaoller en oeppen ring e, foerfarande foer deras framstaellning samt dessa innehaollande farmaceutiska preparat. |
| US5082668A (en) | 1983-05-11 | 1992-01-21 | Alza Corporation | Controlled-release system with constant pushing source |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US4753802A (en) | 1986-03-19 | 1988-06-28 | Alza Corporation | Verapamil dosage form |
| GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US4847093A (en) | 1986-06-19 | 1989-07-11 | Alza Corporation | Dosage form with means for governing rate of gas formation |
| US5057317A (en) | 1987-03-24 | 1991-10-15 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
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| NZ238867A (en) | 1990-07-12 | 1993-08-26 | Alza Corp | Dosage form for delayed release comprising pharmaceutically active substance and a drug-release hindering means and a second composition which imbibes fluid, expands, and ejects the active substance from the device |
| WO1992013547A1 (fr) | 1991-02-07 | 1992-08-20 | Alexander Mellon Eaton | Composition servant a liberer un medicament et procede d'utilisation de la composition |
| US5160744A (en) | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
| US5190765A (en) | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
| US5529992A (en) * | 1992-04-21 | 1996-06-25 | Curators Of The University Of Missouri | Method for inhibiting myocardial fibrosis by administering an aldosterone antagonist which suppresses aldoster one receptors |
| IT1260505B (it) | 1992-06-01 | 1996-04-09 | Poli Ind Chimica Spa | Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon |
| US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
| GB9311191D0 (en) | 1993-05-29 | 1993-07-14 | Danbiosyst Uk | Controlled release drug formulation |
| AU5692398A (en) | 1996-12-09 | 1998-07-03 | Proscript, Inc. | Substituted 5-amino-1,3,4-thiadiazole-2-thiones |
| NZ336004A (en) | 1996-12-11 | 2001-04-27 | G | Process for preparation of 3-keto-7-alpha-alkoxycarbonyl substituted delta-4,5-steroid by reacting 4,5-dihydro-5,7-lactone steroid substrate in the presence of a base |
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| DK1175220T3 (da) * | 1999-12-08 | 2005-08-29 | Pharmacia Corp | Nanopartikulære eplerenonkompositioner |
-
1999
- 1999-08-12 UA UA2001063853A patent/UA74141C2/uk unknown
- 1999-12-07 AR ARP990106255A patent/AR028982A1/es not_active Application Discontinuation
- 1999-12-08 WO PCT/US1999/029136 patent/WO2000033847A1/fr not_active Ceased
- 1999-12-08 US US09/456,614 patent/US6410054B1/en not_active Expired - Lifetime
- 1999-12-08 CN CNB998141100A patent/CN1230179C/zh not_active Expired - Fee Related
- 1999-12-08 EA EA200100519A patent/EA003266B1/ru not_active IP Right Cessation
- 1999-12-08 TR TR2001/01643T patent/TR200101643T2/xx unknown
- 1999-12-08 PL PL349632A patent/PL198425B1/pl not_active IP Right Cessation
- 1999-12-08 JP JP2000586339A patent/JP2002531508A/ja active Pending
- 1999-12-08 HU HU0104718A patent/HU224428B1/hu not_active IP Right Cessation
- 1999-12-08 CZ CZ20011942A patent/CZ20011942A3/cs unknown
- 1999-12-08 BR BR9915964-3A patent/BR9915964A/pt not_active Application Discontinuation
- 1999-12-08 DK DK99963052T patent/DK1135139T3/da active
- 1999-12-08 ID IDW00200101191A patent/ID30115A/id unknown
- 1999-12-08 EP EP99963052A patent/EP1135139B1/fr not_active Expired - Lifetime
- 1999-12-08 CA CA002326842A patent/CA2326842A1/fr not_active Abandoned
- 1999-12-08 AU AU19368/00A patent/AU763166B2/en not_active Expired
- 1999-12-08 IL IL14330199A patent/IL143301A0/xx not_active IP Right Cessation
- 1999-12-08 DE DE69911240T patent/DE69911240T2/de not_active Expired - Lifetime
- 1999-12-08 KR KR1020017007041A patent/KR100671275B1/ko not_active Expired - Fee Related
- 1999-12-08 ES ES99963052T patent/ES2207977T3/es not_active Expired - Lifetime
- 1999-12-08 AT AT99963052T patent/ATE249223T1/de active
- 1999-12-08 HK HK02103113.4A patent/HK1041641B/zh unknown
- 1999-12-08 MY MYPI99005328A patent/MY125651A/en unknown
- 1999-12-08 PT PT99963052T patent/PT1135139E/pt unknown
- 1999-12-08 NZ NZ511869A patent/NZ511869A/en unknown
-
2000
- 2000-02-22 TW TW088121495A patent/TWI234459B/zh not_active IP Right Cessation
-
2001
- 2001-05-25 IS IS5953A patent/IS2325B/is unknown
- 2001-05-28 ZA ZA200104361A patent/ZA200104361B/en unknown
- 2001-06-06 NO NO20012782A patent/NO20012782L/no unknown
-
2002
- 2002-01-31 US US10/066,360 patent/US6592902B2/en not_active Expired - Lifetime
- 2002-03-19 US US10/100,712 patent/US6558707B1/en not_active Expired - Lifetime
- 2002-03-19 US US10/100,930 patent/US6534093B1/en not_active Expired - Lifetime
- 2002-03-19 US US10/101,361 patent/US6495165B1/en not_active Expired - Lifetime
- 2002-11-06 US US10/289,025 patent/US6863902B2/en not_active Expired - Fee Related
-
2004
- 2004-04-02 US US10/817,577 patent/US7157101B2/en not_active Expired - Lifetime
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