DK1135139T3 - Præparater indeholdende mikroniseret eplerenon - Google Patents
Præparater indeholdende mikroniseret eplerenonInfo
- Publication number
- DK1135139T3 DK1135139T3 DK99963052T DK99963052T DK1135139T3 DK 1135139 T3 DK1135139 T3 DK 1135139T3 DK 99963052 T DK99963052 T DK 99963052T DK 99963052 T DK99963052 T DK 99963052T DK 1135139 T3 DK1135139 T3 DK 1135139T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparations containing
- containing micronized
- micronized eplerenone
- eplerenone
- preparations
- Prior art date
Links
- JUKPWJGBANNWMW-VWBFHTRKSA-N eplerenone Chemical compound C([C@@H]1[C@]2(C)C[C@H]3O[C@]33[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)C(=O)OC)C[C@@]21CCC(=O)O1 JUKPWJGBANNWMW-VWBFHTRKSA-N 0.000 title 1
- 229960001208 eplerenone Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11164698P | 1998-12-09 | 1998-12-09 | |
| PCT/US1999/029136 WO2000033847A1 (en) | 1998-12-09 | 1999-12-08 | Micronized eplerenone compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1135139T3 true DK1135139T3 (da) | 2004-01-05 |
Family
ID=22339668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99963052T DK1135139T3 (da) | 1998-12-09 | 1999-12-08 | Præparater indeholdende mikroniseret eplerenon |
Country Status (30)
| Country | Link |
|---|---|
| US (7) | US6410054B1 (da) |
| EP (1) | EP1135139B1 (da) |
| JP (1) | JP2002531508A (da) |
| KR (1) | KR100671275B1 (da) |
| CN (1) | CN1230179C (da) |
| AR (1) | AR028982A1 (da) |
| AT (1) | ATE249223T1 (da) |
| AU (1) | AU763166B2 (da) |
| BR (1) | BR9915964A (da) |
| CA (1) | CA2326842A1 (da) |
| CZ (1) | CZ20011942A3 (da) |
| DE (1) | DE69911240T2 (da) |
| DK (1) | DK1135139T3 (da) |
| EA (1) | EA003266B1 (da) |
| ES (1) | ES2207977T3 (da) |
| HK (1) | HK1041641B (da) |
| HU (1) | HU224428B1 (da) |
| ID (1) | ID30115A (da) |
| IL (1) | IL143301A0 (da) |
| IS (1) | IS2325B (da) |
| MY (1) | MY125651A (da) |
| NO (1) | NO20012782L (da) |
| NZ (1) | NZ511869A (da) |
| PL (1) | PL198425B1 (da) |
| PT (1) | PT1135139E (da) |
| TR (1) | TR200101643T2 (da) |
| TW (1) | TWI234459B (da) |
| UA (1) | UA74141C2 (da) |
| WO (1) | WO2000033847A1 (da) |
| ZA (1) | ZA200104361B (da) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| EP1527782A1 (en) * | 1999-12-08 | 2005-05-04 | Pharmacia Corporation | Nanoparticulate eplerenone compositions |
| ATE293977T1 (de) * | 1999-12-08 | 2005-05-15 | Pharmacia Corp | Nanopartikelzusammensetzungen enthaltend eplerenon |
| AU2001261434A1 (en) * | 2000-05-11 | 2001-11-26 | Pharmacia Corporation | Aldosterone antagonist composition for release during aldosterone acrophase |
| PT1303306E (pt) * | 2000-07-27 | 2006-11-30 | Pharmacia Corp | Terapia de combinação de antagonista de aldosterona epoxiesteróide e de antagonista beta-adrenérgico para tratamento de insuficiência cardíaca congestiva. |
| WO2002009683A2 (en) * | 2000-07-27 | 2002-02-07 | Pharmacia Corporation | Aldosterone blocker therapy to prevent or treat inflammation-related disorders |
| US20020111337A1 (en) * | 2000-08-28 | 2002-08-15 | Fedde Kenton N. | Use of an aldosterone receptor antagonist to improve cognitive function |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| AU2002308295B2 (en) | 2001-03-12 | 2007-08-23 | Intercept Pharmaceuticals, Inc. | Steroids as agonists for FXR |
| US20040173147A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| US6962715B2 (en) * | 2001-10-24 | 2005-11-08 | Hewlett-Packard Development Company, L.P. | Method and dosage form for dispensing a bioactive substance |
| US20040173146A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| GB0114532D0 (en) * | 2001-06-14 | 2001-08-08 | Jagotec Ag | Novel compositions |
| US20030149010A1 (en) * | 2001-07-19 | 2003-08-07 | Keller Bradley T. | Combination of an aldosterone receptor antagonist and an HMG CoA reductase inhibitor |
| CA2469950A1 (en) * | 2001-12-13 | 2003-06-26 | Pharmacia Corporation | Methods for treatment or prophylaxis of aldosterone-mediated pathogenic effectgs in a subject using an epoxy-steroidal aldosterone antagonist |
| EP1469884A1 (en) * | 2002-01-30 | 2004-10-27 | Pharmacia Corporation | Aldosterone antagonist and non-steroidal anti-inflammatory agent combination therapy to prevent or treat cardiovascular disorders |
| CA2476587C (en) * | 2002-02-26 | 2010-05-04 | Astrazeneca Ab | Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative |
| JP2005520856A (ja) * | 2002-03-20 | 2005-07-14 | ファルマシア コーポレーション | 貯蔵時に安定なエプレレノン製剤 |
| US7235655B2 (en) * | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
| PL372055A1 (en) * | 2002-04-26 | 2005-07-11 | Schering Aktiengesellschaft | Treatment of hypertension in women receiving hormone replacement therapy |
| MXPA05002062A (es) * | 2002-08-23 | 2005-06-08 | Pharmacia Corp | Modulacion de la actividad de la metaloproteinasa de la matriz con bloqueador(es) de aldosterona. |
| JP2006503865A (ja) * | 2002-09-30 | 2006-02-02 | アキュスフィア, インコーポレイテッド | 吸入のための徐放性の多孔性微粒子 |
| US7786101B2 (en) * | 2002-11-05 | 2010-08-31 | Bayer Schering Pharma Ag | Cardiovascular protection using anti-aldosteronic progestins |
| AU2003278434A1 (en) * | 2002-11-05 | 2004-06-07 | Schering Aktiengesellschaft | Cardiovascular protection using anti-aldosteronic progestins |
| WO2004041288A1 (en) * | 2002-11-05 | 2004-05-21 | Schering Aktiengesellschaft | Hormone replacement therapy with drospirenone |
| DE60229450D1 (de) * | 2002-12-13 | 2008-11-27 | Jagotec Ag | Topische nanopartikel-spironolacton-formulierung |
| DE10335027A1 (de) | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
| US20060293312A1 (en) * | 2003-04-25 | 2006-12-28 | Howard Dittrich | Method of improved diuresis in individuals with impaired renal function |
| BRPI0409699A (pt) * | 2003-04-25 | 2006-04-18 | Novacardia Inc | métodos de indução do efeito diurético, de indução, manutenção ou restauração do efeito diurético de diurético não modificador de adenosina, de manutenção, restauração ou melhoria da função renal em paciente, de indução de diurese, de prevenção do inìcio de deficiência renal em paciente com sobrecarga de fluidos ou chf, de tratamento de paciente que sofre de chf e de melhoria dos resultados globais da saúde, composição farmacêutica e seus usos |
| KR100473422B1 (ko) * | 2003-06-12 | 2005-03-14 | 박원봉 | 렉틴 함유 천연물의 장용성 코팅용 조성물 |
| EP2529730A1 (en) * | 2003-06-16 | 2012-12-05 | ANDRX Pharmaceuticals LLC. | Oral sustained-release composition |
| US7198653B2 (en) | 2003-07-31 | 2007-04-03 | Delavau Llc | Calcium carbonate granulation |
| US20050031683A1 (en) * | 2003-08-04 | 2005-02-10 | Ashish Kapoor | Solid pharmaceutical composition |
| US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
| US7282217B1 (en) * | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
| DK3395340T3 (da) * | 2003-09-12 | 2019-07-15 | Amgen Inc | Hurtigt opløsende formulering af cinacalcet-hcl |
| CA2533887A1 (en) * | 2003-09-30 | 2005-04-14 | Acusphere, Inc. | Injectable, oral, or topical sustained release pharmaceutical formulations |
| US20050203482A1 (en) * | 2004-03-15 | 2005-09-15 | Chinea Vanessa I. | Pharmaceutical dispensing apparatus and method |
| US20070196471A1 (en) * | 2004-04-02 | 2007-08-23 | Thosar Shilpa S | Micronized Eplerenone Compositions |
| US20050232957A1 (en) * | 2004-04-14 | 2005-10-20 | Katz Kenneth A | Compositions and methods for moisturizing skin |
| EP1755594A1 (en) * | 2004-04-16 | 2007-02-28 | Novacardia, Inc. | Combination therapy comprising an adenosine a1 receptor antagonist and an aldosterone inhibitor |
| US8075910B2 (en) * | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
| US7846466B2 (en) * | 2004-06-10 | 2010-12-07 | Northwestern University | Biodegradable scaffolds and uses thereof |
| US20060134212A1 (en) * | 2004-09-02 | 2006-06-22 | Forest Laboratories, Inc. | Lercanidipine immediate release compositions |
| US20060165788A1 (en) * | 2004-09-09 | 2006-07-27 | Wattanaporn Abramowitz | Lercanidipine pH dependent pulsatile release compositions |
| US20060165789A1 (en) * | 2004-09-09 | 2006-07-27 | Forest Laboratories, Inc. | Lercanidipine modified release compositions |
| US8022053B2 (en) * | 2004-11-02 | 2011-09-20 | Bayer Schering Pharma Aktiengesellschaft | Oral solid dosage forms containing a low dose of estradiol |
| KR100716389B1 (ko) * | 2004-11-23 | 2007-05-11 | 동화약품공업주식회사 | N-히드록시-4-{5-[4-(5-이소프로필-2-메틸-1,3-티아졸-4-일)페녹시]펜톡시}벤즈아미딘 2메탄술폰산염 |
| WO2006097342A1 (en) * | 2005-03-17 | 2006-09-21 | Synthon B.V. | Process for making steroidal compounds |
| US20060252738A1 (en) * | 2005-05-06 | 2006-11-09 | Phero Tech Inc. | Method for preparing and using water-based steroid pheromone compositions |
| US20060275356A1 (en) * | 2005-05-25 | 2006-12-07 | Burgess James W | Pharmaceutical compositions for treating or preventing coronary artery disease |
| WO2007012960A1 (en) * | 2005-07-29 | 2007-02-01 | Glenmark Pharmaceuticals Limited | Pharmaceutical compositions of eplerenone |
| US20070095705A1 (en) * | 2005-10-31 | 2007-05-03 | Legault Dennis X | Array of packages |
| EP2672266B1 (en) * | 2006-01-13 | 2018-08-01 | Indiana University Research & Technology Corporation | Method for screening a lung transplant candidate for an elevated risk of rejection |
| US20070184163A1 (en) * | 2006-02-07 | 2007-08-09 | International Flavors, & Fragrances Inc. | Non-hygroscopic flavor particles |
| WO2007102169A1 (en) * | 2006-03-08 | 2007-09-13 | Jubilant Organosys Limited | Extended release pharmaceutical formulation of venlafaxine and method of manufacturing the same |
| US20070248665A1 (en) * | 2006-04-24 | 2007-10-25 | Sherman Bernard C | Compositions comprising co-precipitate of eplerenone and a water-soluble excipient |
| EP2037887B1 (en) * | 2006-05-31 | 2010-09-15 | Vertex Pharmaceuticals Incorporated | Oral controlled release formulations of an interleukin-1 beta converting enzyme inhibitor |
| CN101466383A (zh) * | 2006-06-16 | 2009-06-24 | 美国诺华卡迪亚公司 | 包含低频率投与aa1ra的肾功能延长改善 |
| DE102006033723A1 (de) * | 2006-07-21 | 2008-01-24 | Bayer Technology Services Gmbh | Formulierungen von Multikompartimenten-Granulaten für Wirkstoffe |
| WO2008021666A2 (en) * | 2006-08-18 | 2008-02-21 | Morton Grove Pharmaceuticals, Inc. | Stable liquid levetiracetam compositions and methods |
| US9138414B1 (en) | 2006-09-15 | 2015-09-22 | Delavau Llc | Calcium supplement having enhanced absorption |
| JP2010513325A (ja) * | 2006-12-21 | 2010-04-30 | アルファファーム ピーティーワイ リミテッド | 医薬組成物 |
| WO2008089549A1 (en) | 2007-01-22 | 2008-07-31 | Genpharm Ulc | Pharmaceutical compositions comprising nebivolol or a nebivolol analogue |
| CA2677193C (en) | 2007-02-01 | 2015-06-30 | Takeda Pharmaceutical Company Limited | Tablet preparation without causing a tableting trouble |
| US20090197900A1 (en) * | 2007-03-29 | 2009-08-06 | Howard Dittrich | Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist |
| WO2008121882A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Improved methods of administration of adenosine a1 receptor antagonists |
| US8372431B2 (en) * | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
| US20090232896A1 (en) * | 2008-03-11 | 2009-09-17 | Mallinckrodt Inc. | Use of Magnesium Stearate Dihydrate for Lubrication of Solid Pharmaceutical Compositions |
| WO2010014952A2 (en) * | 2008-07-31 | 2010-02-04 | Clarke Mosquito Control Products, Inc. | Extended release tablet and method for making and using same |
| GB0814953D0 (en) * | 2008-08-18 | 2008-09-24 | Unilever Plc | Improvements relating to nanodisperse compositions |
| US8545892B2 (en) * | 2009-06-26 | 2013-10-01 | Nano Pharmaceutical Laboratories, Llc | Sustained release beads and suspensions including the same for sustained delivery of active ingredients |
| EP2470165B1 (en) * | 2009-08-28 | 2018-04-18 | Hercules Incorporated | Film coating composition from solid powder compounds |
| US9345848B2 (en) | 2009-10-20 | 2016-05-24 | Sima Patent Ve Lisanslama Hizmetleri Ltd. Sti. | Dry powder inhaler |
| EP2633857B1 (en) | 2009-12-23 | 2015-08-12 | ratiopharm GmbH | Solid pharmaceutical dosage form of ticagrelor and acetylsalicylic acid |
| EA201290556A1 (ru) * | 2009-12-23 | 2013-01-30 | Рациофарм Гмбх | Оральная лекарственная форма, включающая энтекавир |
| UY33455A (es) * | 2010-06-16 | 2012-01-31 | Teijin Pharma Ltd | Tableta con núcleo recubierto de liberación controlada |
| TR201007653A2 (tr) * | 2010-09-20 | 2012-04-24 | Bi̇lgi̇ç Mahmut | Eplerenon içeren farmasötik kompozisyon |
| KR20120093461A (ko) * | 2011-01-27 | 2012-08-23 | 양지화학 주식회사 | 정제형 감미료 조성물 및 그 제조방법 |
| US9849255B2 (en) | 2011-11-25 | 2017-12-26 | Mahmut Bilgic | Inhalation device |
| EP2875359A4 (en) | 2012-03-30 | 2015-08-19 | Charles R Drew University Of Medicine And Science | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLISM SYNDROME DISEASES |
| CA3218491A1 (en) | 2012-06-04 | 2013-12-12 | Pharmacyclics Llc | Crystalline forms of a bruton's tyrosine kinase inhibitor |
| FR3001890B1 (fr) * | 2013-02-08 | 2015-08-07 | Greenpharma Sas | Composition dermatologique pour repousse des poils ou des cheveux |
| US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
| USD744087S1 (en) | 2013-10-01 | 2015-11-24 | Mahmut Bilgic | Dry powder inhaler |
| US11007203B2 (en) * | 2013-10-06 | 2021-05-18 | Salim Shah | Formulations comprising aldosterone receptor antagonists and treatments using same |
| US10716783B2 (en) | 2013-12-12 | 2020-07-21 | Cornell University | Prolylhydroxylase/ATF4 inhibitors and methods of use for treating neural cell injury or death and conditions resulting therefrom |
| FR3019045A1 (fr) * | 2014-03-26 | 2015-10-02 | Greenpharma Sas | Composition dermatologique pour la repousse des poils ou des cheveux |
| MX2017001671A (es) | 2014-08-07 | 2017-07-04 | Pharmacyclics Llc | Formulaciones novedosas de un inhibidor de la tirosina cinasa de bruton. |
| WO2016063269A1 (en) | 2014-10-20 | 2016-04-28 | Prendergast Patrick T | Use of antagonists to the nuclear steroid receptor alone or in combination as direct antiviral agents to inhibit alphavirus, togaviridae, arenaviridae, filoviridae, bunyaviridae, flaviviridae and rhabdoviridae |
| WO2016114812A1 (en) | 2015-01-12 | 2016-07-21 | Robert Niichel | Layered sustained-release microbeads and methods of making the same |
| IL315294A (en) | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of bruton's tyrosine kinase inhibitor |
| GB201913972D0 (en) * | 2019-09-27 | 2019-11-13 | Univ Ulster | Pharmaceutical Delivery Device and method of manufacture |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082751A (en) * | 1976-02-13 | 1978-04-04 | Bristol-Myers Company | Therapeutic agents |
| IT1130924B (it) * | 1980-03-06 | 1986-06-18 | Secifarma Spa | Procedimento per la preparazione di spironolattone micronizzato |
| US4559332A (en) * | 1983-04-13 | 1985-12-17 | Ciba Geigy Corporation | 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof |
| US5082668A (en) | 1983-05-11 | 1992-01-21 | Alza Corporation | Controlled-release system with constant pushing source |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US4753802A (en) | 1986-03-19 | 1988-06-28 | Alza Corporation | Verapamil dosage form |
| GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US4847093A (en) | 1986-06-19 | 1989-07-11 | Alza Corporation | Dosage form with means for governing rate of gas formation |
| US5057317A (en) | 1987-03-24 | 1991-10-15 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
| GB8717168D0 (en) | 1987-07-21 | 1987-08-26 | Roussel Lab Ltd | Controlled-release device |
| NZ238867A (en) | 1990-07-12 | 1993-08-26 | Alza Corp | Dosage form for delayed release comprising pharmaceutically active substance and a drug-release hindering means and a second composition which imbibes fluid, expands, and ejects the active substance from the device |
| AU1432292A (en) | 1991-02-07 | 1992-09-07 | Lawrence Samuel Bass | Drug delivery composition and method of using the same |
| US5190765A (en) | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
| US5160744A (en) | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
| US5529992A (en) * | 1992-04-21 | 1996-06-25 | Curators Of The University Of Missouri | Method for inhibiting myocardial fibrosis by administering an aldosterone antagonist which suppresses aldoster one receptors |
| IT1260505B (it) | 1992-06-01 | 1996-04-09 | Poli Ind Chimica Spa | Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon |
| US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
| GB9311191D0 (en) | 1993-05-29 | 1993-07-14 | Danbiosyst Uk | Controlled release drug formulation |
| WO1998025949A1 (en) | 1996-12-09 | 1998-06-18 | Proscript, Inc. | Substituted 5-amino-1,3,4-thiadiazole-2-thiones |
| ATE225367T1 (de) | 1996-12-11 | 2002-10-15 | Searle & Co | Verfahren zur herstellung von 3-keto-7alpha- alkoxycarbonyl- delta4,5-steroiden sowie zwischenprodukte |
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| ATE293977T1 (de) * | 1999-12-08 | 2005-05-15 | Pharmacia Corp | Nanopartikelzusammensetzungen enthaltend eplerenon |
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1999
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- 1999-12-07 AR ARP990106255A patent/AR028982A1/es not_active Application Discontinuation
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- 1999-12-08 CA CA002326842A patent/CA2326842A1/en not_active Abandoned
- 1999-12-08 HU HU0104718A patent/HU224428B1/hu not_active IP Right Cessation
- 1999-12-08 MY MYPI99005328A patent/MY125651A/en unknown
- 1999-12-08 TR TR2001/01643T patent/TR200101643T2/xx unknown
- 1999-12-08 IL IL14330199A patent/IL143301A0/xx not_active IP Right Cessation
- 1999-12-08 ES ES99963052T patent/ES2207977T3/es not_active Expired - Lifetime
- 1999-12-08 DK DK99963052T patent/DK1135139T3/da active
- 1999-12-08 KR KR1020017007041A patent/KR100671275B1/ko not_active Expired - Fee Related
- 1999-12-08 CZ CZ20011942A patent/CZ20011942A3/cs unknown
- 1999-12-08 ID IDW00200101191A patent/ID30115A/id unknown
- 1999-12-08 AU AU19368/00A patent/AU763166B2/en not_active Expired
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- 1999-12-08 WO PCT/US1999/029136 patent/WO2000033847A1/en not_active Ceased
- 1999-12-08 CN CNB998141100A patent/CN1230179C/zh not_active Expired - Fee Related
- 1999-12-08 DE DE69911240T patent/DE69911240T2/de not_active Expired - Lifetime
- 1999-12-08 PL PL349632A patent/PL198425B1/pl not_active IP Right Cessation
- 1999-12-08 US US09/456,614 patent/US6410054B1/en not_active Expired - Lifetime
- 1999-12-08 AT AT99963052T patent/ATE249223T1/de active
- 1999-12-08 NZ NZ511869A patent/NZ511869A/en unknown
- 1999-12-08 HK HK02103113.4A patent/HK1041641B/zh unknown
- 1999-12-08 JP JP2000586339A patent/JP2002531508A/ja active Pending
- 1999-12-08 EP EP99963052A patent/EP1135139B1/en not_active Expired - Lifetime
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2000
- 2000-02-22 TW TW088121495A patent/TWI234459B/zh not_active IP Right Cessation
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2001
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- 2001-05-28 ZA ZA200104361A patent/ZA200104361B/en unknown
- 2001-06-06 NO NO20012782A patent/NO20012782L/no unknown
-
2002
- 2002-01-31 US US10/066,360 patent/US6592902B2/en not_active Expired - Lifetime
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- 2002-03-19 US US10/101,361 patent/US6495165B1/en not_active Expired - Lifetime
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