[go: up one dir, main page]

HUP9903658A2 - Bukkális adagolórendszer - Google Patents

Bukkális adagolórendszer

Info

Publication number
HUP9903658A2
HUP9903658A2 HU9903658A HUP9903658A HUP9903658A2 HU P9903658 A2 HUP9903658 A2 HU P9903658A2 HU 9903658 A HU9903658 A HU 9903658A HU P9903658 A HUP9903658 A HU P9903658A HU P9903658 A2 HUP9903658 A2 HU P9903658A2
Authority
HU
Hungary
Prior art keywords
amount
present
cellulose acetate
optionally
swellable
Prior art date
Application number
HU9903658A
Other languages
English (en)
Inventor
Kimon Ventouras
Original Assignee
Novartis Consumer Health S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Consumer Health S.A. filed Critical Novartis Consumer Health S.A.
Publication of HUP9903658A2 publication Critical patent/HUP9903658A2/hu
Publication of HUP9903658A3 publication Critical patent/HUP9903658A3/hu
Publication of HU224035B1 publication Critical patent/HU224035B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány lassan szétmálló pasztilla főrmájában levő bűkkálisleadórendszerre vőnatkőzik, amelyből a hatóanyag a bűkkálisnyálkahártyán hősszabb, példáűl 15 és 90 perc közötti idő alattszabadűl fel. A találmány szerinti pasztilla, amely őldódótöltőanyagból, nemőldódó filmképző anyagból, dűzzadó pőlimerből és máskőmpőnensekből áll, közel nűlladrendű hatóanyag-leadással és kellemesőrganőleptikűs tűlajdőnságőkkal rendelkezik. ŕ
HU9903658A 1996-05-13 1997-05-06 Bukkális adagolórendszer HU224035B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96810303 1996-05-13
PCT/EP1997/002299 WO1997042941A2 (en) 1996-05-13 1997-05-06 Buccal delivery system

Publications (3)

Publication Number Publication Date
HUP9903658A2 true HUP9903658A2 (hu) 2000-03-28
HUP9903658A3 HUP9903658A3 (en) 2000-04-28
HU224035B1 HU224035B1 (hu) 2005-05-30

Family

ID=8225608

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903658A HU224035B1 (hu) 1996-05-13 1997-05-06 Bukkális adagolórendszer

Country Status (21)

Country Link
US (1) US6183775B1 (hu)
EP (1) EP0906089B1 (hu)
JP (1) JP3707798B2 (hu)
CN (1) CN1159000C (hu)
AT (1) ATE247951T1 (hu)
AU (1) AU2891997A (hu)
BR (1) BR9709452B1 (hu)
CA (1) CA2251623C (hu)
CY (1) CY2497B1 (hu)
CZ (1) CZ298212B6 (hu)
DE (1) DE69724424T2 (hu)
DK (1) DK0906089T3 (hu)
ES (1) ES2206709T3 (hu)
HU (1) HU224035B1 (hu)
NO (1) NO321608B1 (hu)
PL (1) PL187242B1 (hu)
PT (1) PT906089E (hu)
RU (1) RU2192245C2 (hu)
TR (1) TR199802305T2 (hu)
WO (1) WO1997042941A2 (hu)
ZA (1) ZA974077B (hu)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US6344222B1 (en) 1998-09-03 2002-02-05 Jsr Llc Medicated chewing gum delivery system for nicotine
US6248760B1 (en) * 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
EP1118321A1 (fr) * 2000-01-14 2001-07-25 Ucb, S.A. Compositions pharmaceutiques solides pour la libération contrôlée de substances actives
FR2803720B1 (fr) 2000-01-18 2004-10-22 Roquette Freres Lozenges a base de dextrose et leur procede de fabrication
IL135061A0 (en) * 2000-03-14 2001-05-20 Ahron Jodaikin Strategic targeted fluoridation and chemical treatment of teeth
US20050175959A1 (en) * 2000-03-14 2005-08-11 Coll Partners Ltd. System for the controlled delivery of an active material to a dental site
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
WO2002019920A1 (en) 2000-09-08 2002-03-14 Coleman James E Surgical staple
US6756051B1 (en) 2000-11-15 2004-06-29 Li-Lan H. Chen Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
US6695867B2 (en) 2002-02-21 2004-02-24 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US6623510B2 (en) 2000-12-07 2003-09-23 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
FR2823974B1 (fr) 2001-04-25 2004-10-15 Pf Medicament Pastille medicamenteuse a liberation lente du principe actif
SE0102197D0 (sv) * 2001-06-20 2001-06-20 Pharmacia Ab New product and use and manufacture thereof
MXPA03000985A (es) * 2001-07-27 2004-04-02 Yamanouchi Pharma Co Ltd Composicion que comprende particulas finas de liberacion sostenida para tabletas de desintegracion rapida en la cavidad bucal y metodo de fabricacion de la misma.
WO2003059542A1 (en) 2002-01-17 2003-07-24 Lts Lohmann Therapie-Systeme Ag Method for neutralizing or recycling carrier materials for film-like coatings
US20030148818A1 (en) * 2002-01-18 2003-08-07 Myrhum Mark C. Golf club woods with wood club head having a selectable center of gravity and a selectable shaft
FR2834890B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'agomelatine
SE0201669D0 (sv) * 2002-06-03 2002-06-03 Pharmacia Ab New formulation and use thereof
IES20030424A2 (en) 2002-06-04 2003-12-10 Robert Stevenson Blood vessel closure clip and delivery device
DE10224612A1 (de) * 2002-06-04 2003-12-24 Lohmann Therapie Syst Lts Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung
JP2004026725A (ja) * 2002-06-26 2004-01-29 Sunstar Inc 固形製剤
US20040052851A1 (en) * 2002-09-16 2004-03-18 Graff Allan H. Modified release oral dosage form
ES2209649B1 (es) * 2002-12-09 2005-03-16 Carlos Arana Molina (Titular Al 25%) Utilizacion de la melatonina para la higiene bucodental para uso humano y veterinario como producto activo.
ES2708552T3 (es) * 2002-12-20 2019-04-10 Niconovum Ab Método para la preparación de un material particulado que contiene nicotina con una celulosa cristalina (en particular MCC)
EA012306B1 (ru) * 2003-01-24 2009-08-28 Магле Холдинг Аб Композиционный материал для доставки через слизистые оболочки
SE0302947D0 (sv) 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US20040151771A1 (en) * 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
IL155666A (en) * 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
US7306812B2 (en) 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
TW200514579A (en) 2003-07-24 2005-05-01 Smithkline Beecham Corp Orally dissolving films
US20050034738A1 (en) * 2003-08-11 2005-02-17 Whalen William F. Chewing tobacco substitute containing nicotine
US20060112965A1 (en) * 2003-08-11 2006-06-01 Whalen William F Chewing tobacco substitute containing cotinine
GB0320854D0 (en) * 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
US20050065175A1 (en) * 2003-09-24 2005-03-24 Xanodyne Pharmacal, Inc. Oral transmucosal methadone
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
WO2005046363A2 (en) 2003-11-07 2005-05-26 U.S. Smokeless Tobacco Company Tobacco compositions
AU2005284908B2 (en) 2004-09-13 2011-12-08 Morningside Venture Investments Limited Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
CN101262786B (zh) * 2005-05-25 2015-04-08 美国无烟烟草有限责任公司 烟草组合物
US8313497B2 (en) 2005-07-01 2012-11-20 Abbott Laboratories Clip applier and methods of use
JP2007210905A (ja) * 2006-02-07 2007-08-23 Asahi Breweries Ltd 口腔内用顆粒、錠剤およびその製造方法
WO2007104573A2 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US7754234B2 (en) * 2006-07-12 2010-07-13 Jones Thomas L Composition and method of treating a sore throat
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
CA2661575C (en) * 2006-08-18 2014-06-17 Losan Pharma Gmbh Pharmaceutical compositions easy to swallow, not causing any unpleasant oral sensation and comprising particles with an active principle
US8889184B2 (en) 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
EP1891936A1 (de) * 2006-08-18 2008-02-27 Losan Pharma GmbH Gut schluckbare pharmazeutische Zusammensetzung aus einem oder mehreren wirkstoffhaltigen Teilchen ohne unangenehmes Mundgefühl
WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
CA2677281C (en) * 2007-02-09 2019-10-29 Durect Corporation Transoral dosage forms comprising sufentanil and naloxone
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080286341A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
US7850453B2 (en) * 2007-08-08 2010-12-14 Coll Partners Ltd. Reshapable device for fixation at a dental site
PL2224914T3 (pl) 2007-09-14 2015-11-30 Wockhardt Ltd Kompozycje diacereiny
US20090081294A1 (en) * 2007-09-26 2009-03-26 Gin Jerry B Sustained release dosage form for lubricating an oral cavity
AR071420A1 (es) 2008-05-01 2010-06-16 Smithkline Beecham Corp Composicion de pastilla para chupar oral que comprende un principio activo de nicotina y procedimiento para fabricarla
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US9241696B2 (en) 2008-10-30 2016-01-26 Abbott Vascular Inc. Closure device
US20100179589A1 (en) * 2009-01-09 2010-07-15 Abbott Vascular Inc. Rapidly eroding anchor
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US20100185234A1 (en) 2009-01-16 2010-07-22 Abbott Vascular Inc. Closure devices, systems, and methods
US20100256215A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Menthol-Melatonin Dissolving Film
US20110054492A1 (en) 2009-08-26 2011-03-03 Abbott Laboratories Medical device for repairing a fistula
WO2011100643A1 (en) * 2010-02-12 2011-08-18 Sensient Colors Inc. Enteric coating compositions and methods of making and using the same
PH12012501487A1 (en) 2010-02-18 2016-07-27 Jatin Vasant Thakkar Nicotine-containing soft gelatin pastilles
UA112974C2 (uk) 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
LT2701681T (lt) * 2011-04-29 2016-12-12 Moberg Pharma Ab Farmacinės kompozicijos, apimančios vietinį anestetiką, tokį kaip bupivakainas, skirts vietiniam įvedimui į burną arba į gerklę
EP2729148A4 (en) 2011-07-06 2015-04-22 Parkinson S Inst COMPOSITIONS AND METHOD FOR THE TREATMENT OF SYMPTOMS IN PATIENTS WITH MORBUS PARKINSON
FR2978916B1 (fr) * 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9084439B2 (en) * 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US20130177646A1 (en) * 2012-01-05 2013-07-11 Mcneil Ab Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9044035B2 (en) 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
FR2993778B1 (fr) * 2012-07-30 2016-06-17 Pf Medicament Pastilles a cinetiques multiples de liberation de principes actifs
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
TW201507726A (zh) 2013-05-10 2015-03-01 Glaxosmithkline Llc 菸鹼菱形錠配製物
US9668844B2 (en) 2013-11-06 2017-06-06 Colldent Y.A Ltd Device for fixation at a dental site
WO2016123406A1 (en) 2015-01-28 2016-08-04 Chrono Therapeutics Inc. Drug delivery methods and systems
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
CA3101966A1 (en) 2018-05-29 2019-12-05 Morningside Venture Investments Limited Drug delivery methods and systems
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
WO2020136620A1 (en) 2018-12-29 2020-07-02 3M Innovative Properties Company Oral articles and methods of use
PL3946262T3 (pl) * 2019-08-30 2024-11-25 Evie Sa Wypełnione granulki, sposób ich wytwarzania i ich zastosowania
US20210106516A1 (en) * 2019-10-11 2021-04-15 Fertin Pharma A/S Ion-Exchange Composition With Water-Soluble Mucoadhesive Polymers
CN113208156B (zh) * 2021-05-07 2022-08-12 云南中烟工业有限责任公司 一种基于柠檬酸尼古丁盐胶凝剂的载香超分子凝胶

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206209A (en) 1978-11-02 1980-06-03 Kracauer Paul Sublingual aspirin tablet
CA1208558A (en) 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
GB8317576D0 (en) 1983-06-29 1983-08-03 Shaw A S W Consumer tobacco products
LU85058A1 (fr) 1983-10-24 1985-06-19 Pharlyse Comprimes pharmaceutiques a liberation prolongee,leur preparation et leur utilisation
US4680323A (en) * 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
BE899037A (fr) 1984-02-29 1984-06-18 Trenker Ady Composition a sucer permettant de cesser de fumer
US4863737A (en) 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US5288497A (en) 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
GB8615676D0 (en) 1986-06-26 1986-07-30 Stoppers Co Ltd Nicotine containing lozenge
IL85538A (en) * 1987-02-27 1991-09-16 Lilly Co Eli Sustained release matrix tablet formulations containing hydrophilic and enteric polymers
KR960011236B1 (ko) * 1987-05-08 1996-08-21 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 제약학적 조성물 및 고체 제형
GB8928196D0 (en) * 1989-12-13 1990-02-14 Merrell Dow Pharmaceuticals Li Pharmaceutical lozenges
SE8904295D0 (sv) 1989-12-21 1989-12-21 Pharmacia Ab Smoking substitute
GB9111224D0 (en) 1991-05-24 1991-07-17 Charwell Consumer Prod Smoking substitute preparation
RU2109509C1 (ru) * 1991-12-24 1998-04-27 Яманути Фармасьютикал Ко., Лтд. Композиция для буккального введения лекарственного средства и способ ее получения
FR2699074B1 (fr) 1992-12-11 1995-03-03 Georges Grimberg Procédé d'obtention d'un médicament se présentant sous la forme d'un produit comprimé pouvant être avalé, sucé, croqué, délité.
US5496541C1 (en) * 1993-01-19 2001-06-26 Squigle Inc Tasteful toothpaste and other dental products
US5549906A (en) 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
DE4333190C2 (de) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung
MA23587A1 (fr) * 1994-06-23 1995-12-31 Procter & Gamble Traitement du besoin en nicotine et/ou du syndrome de manque lie au tabagisme

Also Published As

Publication number Publication date
BR9709452B1 (pt) 2008-11-18
CA2251623C (en) 2006-12-19
HK1019199A1 (en) 2000-01-28
PT906089E (pt) 2004-01-30
RU2192245C2 (ru) 2002-11-10
CZ298212B6 (cs) 2007-07-25
EP0906089A2 (en) 1999-04-07
ATE247951T1 (de) 2003-09-15
PL187242B1 (pl) 2004-06-30
DE69724424D1 (de) 2003-10-02
DE69724424T2 (de) 2004-06-24
CN1159000C (zh) 2004-07-28
NO321608B1 (no) 2006-06-12
HUP9903658A3 (en) 2000-04-28
CA2251623A1 (en) 1997-11-20
ES2206709T3 (es) 2004-05-16
JP3707798B2 (ja) 2005-10-19
WO1997042941A3 (en) 1997-12-24
DK0906089T3 (da) 2003-12-08
HU224035B1 (hu) 2005-05-30
CN1218395A (zh) 1999-06-02
PL329744A1 (en) 1999-04-12
TR199802305T2 (xx) 2002-06-21
AU2891997A (en) 1997-12-05
ZA974077B (en) 1997-11-24
CY2497B1 (en) 2005-09-02
US6183775B1 (en) 2001-02-06
BR9709452A (pt) 1999-08-10
WO1997042941A2 (en) 1997-11-20
JP2000504028A (ja) 2000-04-04
CZ365998A3 (cs) 1999-02-17
NO984773L (no) 1998-10-13
NO984773D0 (no) 1998-10-13
EP0906089B1 (en) 2003-08-27

Similar Documents

Publication Publication Date Title
PL329744A1 (en) Buccal delivery system
RU98122230A (ru) Трансбуккальная система доставки
US5876759A (en) Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
ES2376199T3 (es) Un comprimido farmacéutico caracterizado por mostrar un incremento de volumen cuando entra en contacto con fluidos biológicos.
ES2299234T3 (es) Comprimidos masticables blandos.
ES2540972T3 (es) Comprimido de liberación controlada por via oral con un núcleo unitario
CA2170504A1 (en) Compositions and methods for the administration of u-aminolevulinic acid
US20090263467A1 (en) Combination drug therapy using orally dissolving film or orally disintegrating tablet dosage forms to treat dry mouth ailments
JP2003095947A (ja) ニコチン含有フィルム製剤
US20230033638A1 (en) Soluble rear layer for otf
WO2001049292A1 (en) Oral mucosal dosage forms of apomorphine
KR0184350B1 (ko) 오메프라졸 구강점막 부착 정제 조성물
US20050152973A1 (en) Disintegrant
HK1019199B (en) Buccal delivery system
WO2013109204A1 (en) Compositions comprising cefditoren pivoxil
WO2013109228A1 (en) Formulations comprising cefixime as active agent
MXPA96003713A (en) Sublingual pharmaceutical composition or bu

Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20050322