HUE035999T2 - Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában - Google Patents
Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisábanInfo
- Publication number
- HUE035999T2 HUE035999T2 HUE12842377A HUE12842377A HUE035999T2 HU E035999 T2 HUE035999 T2 HU E035999T2 HU E12842377 A HUE12842377 A HU E12842377A HU E12842377 A HUE12842377 A HU E12842377A HU E035999 T2 HUE035999 T2 HU E035999T2
- Authority
- HU
- Hungary
- Prior art keywords
- citrulated
- peptides
- diagnosis
- rheumatoid arthritis
- antigens derived
- Prior art date
Links
- 102000004899 14-3-3 Proteins Human genes 0.000 title 1
- 101000723543 Homo sapiens 14-3-3 protein theta Proteins 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 206010039073 rheumatoid arthritis Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/18—Post-translational modifications [PTMs] in chemical analysis of biological material citrullination
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161550046P | 2011-10-21 | 2011-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE035999T2 true HUE035999T2 (hu) | 2018-06-28 |
Family
ID=48140274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE12842377A HUE035999T2 (hu) | 2011-10-21 | 2012-10-19 | Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US10132806B2 (hu) |
| EP (1) | EP2768851B1 (hu) |
| JP (2) | JP6844939B2 (hu) |
| KR (1) | KR20140100939A (hu) |
| CN (1) | CN104011068A (hu) |
| AU (1) | AU2012325604B2 (hu) |
| BR (1) | BR112014009536A2 (hu) |
| CA (1) | CA2852758C (hu) |
| DK (1) | DK2768851T3 (hu) |
| ES (1) | ES2638331T3 (hu) |
| HU (1) | HUE035999T2 (hu) |
| IL (1) | IL232169B (hu) |
| IN (1) | IN2014DN03200A (hu) |
| PL (1) | PL2768851T3 (hu) |
| PT (1) | PT2768851T (hu) |
| WO (1) | WO2013056377A1 (hu) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104011068A (zh) * | 2011-10-21 | 2014-08-27 | 奥古雷克斯生命科学公司 | 衍生自瓜氨酸化的14-3-3的抗原及其在风湿性关节炎诊断中的用途 |
| ES2674393T3 (es) * | 2014-05-05 | 2018-06-29 | Novio Th B.V. | Método para el diagnóstico serológico de la artritis reumatoide |
| CN104262489B (zh) * | 2014-09-30 | 2017-01-11 | 陈仁奋 | 一种环状瓜氨酸嵌合肽抗原及其应用 |
| KR101758354B1 (ko) | 2015-03-26 | 2017-07-17 | 한국과학기술연구원 | 신규한 시클릭 시트룰리네이티드 펩티드, 이를 포함하는 류마티스 관절염 진단용 조성물 및 이를 이용한 진단 방법, 및 류마티스 관절염 마커 스크리닝 방법 |
| AU2016303033A1 (en) * | 2015-08-06 | 2018-03-01 | Novimmune Sa | Methods and compositions for identifying patient populations for diagnosis and treatment of TLR4-dependent disorders |
| JP2019508415A (ja) * | 2016-02-10 | 2019-03-28 | ケイマン ケミカル カンパニー， インコーポレーテッド | 抗シトルリン化ｈｌａポリペプチド抗体及びその使用 |
| CN106644985B (zh) * | 2016-12-29 | 2021-02-05 | 广州市雷德生物科技有限公司 | 标志物及其应用、试剂盒、该标志物的检测方法 |
| KR102529594B1 (ko) * | 2021-06-23 | 2023-05-09 | 재단법인 아산사회복지재단 | 대동맥판막 협착증 진단 및 예후 예측을 위한 바이오마커로서 항-시트룰린화 펩티드 항체의 용도 |
| CN119464241A (zh) * | 2023-08-09 | 2025-02-18 | 厦门大学 | 瓜氨酸化setdb1多肽及其在诊断类风湿性关节炎中的应用 |
| CN118240057B (zh) * | 2024-05-28 | 2024-07-23 | 北京大学人民医院 | 一种抗原肽及其在制备类风湿关节炎诊断产品中的应用 |
| CN119874879B (zh) * | 2025-03-27 | 2025-07-01 | 北京大学人民医院 | 瓜氨酸化saa多肽及在制备类风湿关节炎诊断产品中的应用 |
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| CN104011068A (zh) * | 2011-10-21 | 2014-08-27 | 奥古雷克斯生命科学公司 | 衍生自瓜氨酸化的14-3-3的抗原及其在风湿性关节炎诊断中的用途 |
-
2012
- 2012-10-19 CN CN201280058618.2A patent/CN104011068A/zh active Pending
- 2012-10-19 HU HUE12842377A patent/HUE035999T2/hu unknown
- 2012-10-19 PT PT128423779T patent/PT2768851T/pt unknown
- 2012-10-19 JP JP2014536080A patent/JP6844939B2/ja active Active
- 2012-10-19 ES ES12842377.9T patent/ES2638331T3/es active Active
- 2012-10-19 KR KR1020147013572A patent/KR20140100939A/ko not_active Ceased
- 2012-10-19 WO PCT/CA2012/050748 patent/WO2013056377A1/en not_active Ceased
- 2012-10-19 PL PL12842377T patent/PL2768851T3/pl unknown
- 2012-10-19 US US14/353,281 patent/US10132806B2/en active Active
- 2012-10-19 BR BR112014009536A patent/BR112014009536A2/pt not_active IP Right Cessation
- 2012-10-19 DK DK12842377.9T patent/DK2768851T3/en active
- 2012-10-19 EP EP12842377.9A patent/EP2768851B1/en active Active
- 2012-10-19 AU AU2012325604A patent/AU2012325604B2/en active Active
- 2012-10-19 CA CA2852758A patent/CA2852758C/en active Active
-
2014
- 2014-04-22 IL IL232169A patent/IL232169B/en active IP Right Grant
- 2014-04-22 IN IN3200DEN2014 patent/IN2014DN03200A/en unknown
-
2018
- 2018-11-19 US US16/195,582 patent/US11913950B2/en active Active
-
2019
- 2019-01-30 JP JP2019014527A patent/JP2019081774A/ja active Pending
-
2024
- 2024-02-26 US US18/587,846 patent/US20250093349A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DK2768851T3 (en) | 2017-09-18 |
| US20140255957A1 (en) | 2014-09-11 |
| BR112014009536A2 (pt) | 2017-04-18 |
| US11913950B2 (en) | 2024-02-27 |
| EP2768851A4 (en) | 2015-03-11 |
| PL2768851T3 (pl) | 2018-05-30 |
| CA2852758C (en) | 2020-12-29 |
| US20250093349A1 (en) | 2025-03-20 |
| IL232169A0 (en) | 2014-06-30 |
| IL232169B (en) | 2018-12-31 |
| HK1201538A1 (en) | 2015-09-04 |
| JP2014530826A (ja) | 2014-11-20 |
| US10132806B2 (en) | 2018-11-20 |
| EP2768851A1 (en) | 2014-08-27 |
| AU2012325604A1 (en) | 2014-06-05 |
| CA2852758A1 (en) | 2013-04-25 |
| US20190310249A1 (en) | 2019-10-10 |
| CN104011068A (zh) | 2014-08-27 |
| PT2768851T (pt) | 2017-09-08 |
| WO2013056377A1 (en) | 2013-04-25 |
| KR20140100939A (ko) | 2014-08-18 |
| AU2012325604B2 (en) | 2017-08-03 |
| JP6844939B2 (ja) | 2021-03-17 |
| ES2638331T3 (es) | 2017-10-19 |
| EP2768851B1 (en) | 2017-05-31 |
| JP2019081774A (ja) | 2019-05-30 |
| IN2014DN03200A (hu) | 2015-05-22 |
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