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HUE026613T2 - Halogénezett benzamid-származékok - Google Patents

Halogénezett benzamid-származékok

Info

Publication number
HUE026613T2
HUE026613T2 HUE05800142A HUE05800142A HUE026613T2 HU E026613 T2 HUE026613 T2 HU E026613T2 HU E05800142 A HUE05800142 A HU E05800142A HU E05800142 A HUE05800142 A HU E05800142A HU E026613 T2 HUE026613 T2 HU E026613T2
Authority
HU
Hungary
Prior art keywords
benzamide derivatives
halogenated benzamide
halogenated
derivatives
benzamide
Prior art date
Application number
HUE05800142A
Other languages
English (en)
Inventor
Jean Francois Rossignol
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of HUE026613T2 publication Critical patent/HUE026613T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HUE05800142A 2004-09-09 2005-09-06 Halogénezett benzamid-származékok HUE026613T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60835404P 2004-09-09 2004-09-09

Publications (1)

Publication Number Publication Date
HUE026613T2 true HUE026613T2 (hu) 2016-06-28

Family

ID=36060542

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE05800142A HUE026613T2 (hu) 2004-09-09 2005-09-06 Halogénezett benzamid-származékok

Country Status (25)

Country Link
US (3) US7285567B2 (hu)
EP (1) EP1789040B1 (hu)
JP (1) JP4998852B2 (hu)
KR (1) KR101344984B1 (hu)
CN (1) CN101035531B (hu)
AP (1) AP2451A (hu)
AU (1) AU2005285157B2 (hu)
BR (1) BRPI0515089B8 (hu)
CA (1) CA2580347C (hu)
CY (1) CY1118689T1 (hu)
DK (1) DK1789040T3 (hu)
EA (1) EA012606B1 (hu)
ES (1) ES2559672T3 (hu)
HR (1) HRP20151439T1 (hu)
HU (1) HUE026613T2 (hu)
IL (2) IL181849A (hu)
ME (1) ME02370B (hu)
MX (1) MX2007002969A (hu)
PL (1) PL1789040T3 (hu)
PT (1) PT1789040E (hu)
RS (1) RS54453B1 (hu)
SI (1) SI1789040T1 (hu)
UA (1) UA90864C2 (hu)
WO (1) WO2006031566A2 (hu)
ZA (1) ZA200702066B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE485275T1 (de) * 2002-02-12 2010-11-15 Glaxosmithkline Llc Nicotinamide und deren verwendung als p38 inhibitoren
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
WO2006110814A2 (en) * 2005-04-12 2006-10-19 Romark Laboratories, L.C. Methods for treating diseases through inhibition the function of molecular chaperones such as protein disulfide isomerases, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
CN101448497B (zh) 2006-01-09 2013-07-10 罗马克实验室有限公司 包含硝唑尼特、替唑尼特、或其混合物的组合物在制备治疗丙型肝炎药物中的应用
AU2008299781B2 (en) 2007-08-03 2013-11-14 Romark Laboratories L.C. Alkylsulfonyl-substituted thiazolide compounds
LT2395840T (lt) 2009-02-13 2020-07-10 Romark Laboratories, L.C. Nitazoksanido kontroliuojamo atpalaidavimo farmacinės kompozicijos
KR101760956B1 (ko) * 2009-05-12 2017-07-24 로마크 레버러토리즈, 엘.씨. 할로알킬 헤테로아릴 벤즈아미드 화합물
KR20180032689A (ko) * 2009-06-26 2018-03-30 로마크 레버러토리즈, 엘.씨. 인플루엔자를 치료하기 위한 화합물 및 방법
CN102335171B (zh) * 2010-07-27 2013-09-11 中国农业科学院上海兽医研究所 一类n-(2-噻唑)苯甲酰胺衍生物的应用
MX2013013115A (es) 2011-05-16 2014-02-27 Romark Lab Lc Uso de compuestos de tiazolida para la prevencion y tratamiento de enfermedades virales, cancer y enfermedades causadas por infecciones intracelulares.
US9650369B2 (en) * 2012-09-28 2017-05-16 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
KR20170081228A (ko) * 2014-11-11 2017-07-11 로마크 레버러토리즈, 엘.씨. 티족사나이드, 그의 유사체 또는 염의 전구 약물을 이용한 치료 조성물 및 방법
HUE050601T2 (hu) 2016-03-31 2020-12-28 Romark Laboratories Lc Tiazolidvegyületek vírusfertõzések kezelésére
PH12018502142B1 (en) 2016-04-11 2023-08-11 Genfit Methods of treatment for cholestatic and fibrotic diseases
US11173149B2 (en) 2017-04-18 2021-11-16 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase A3
EP4182304A1 (en) 2020-07-20 2023-05-24 Romark Laboratories, L.C. Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine
CN116367892A (zh) 2020-08-24 2023-06-30 罗马克实验室有限公司 噻唑化物抗冠状病毒的用途
CN115197164B (zh) * 2021-04-12 2025-04-01 杜心赟 新型噻唑类化合物及其制备方法和用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1276663A (en) 1968-12-24 1972-06-07 Ici Ltd Stimulation of plant growth
CA946845A (en) 1970-04-15 1974-05-07 Shell Internationale Research Maatschappij, N.V. Fungicidal compounds
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
JPS60205454A (ja) * 1984-03-29 1985-10-17 Mitsubishi Paper Mills Ltd 電子写真感光体
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5578621A (en) 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
CN1072654C (zh) 1994-04-13 2001-10-10 让-弗兰克伊斯·罗西格诺尔 苯甲酰胺衍生物,含所述衍生物的组合物及它们的用途
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
DE19528046A1 (de) * 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
US5935591A (en) * 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
CN1440383A (zh) * 2000-04-28 2003-09-03 三共株式会社 PPARγ调制剂
WO2002006093A1 (en) * 2000-07-14 2002-01-24 Breed Automotive Technology, Inc. Energy absorbing seat belt retractor
UA82827C2 (en) 2000-12-18 2008-05-26 Inhibitors against the production and release of inflammatory cytokines
JP2003064056A (ja) * 2001-08-27 2003-03-05 Sankyo Co Ltd アミド誘導体
WO2003035602A1 (en) * 2001-10-25 2003-05-01 Sankyo Company, Limited Lipid modulators
US20060122243A1 (en) * 2002-06-06 2006-06-08 Susumu Muto Antiallergic
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
UA86614C2 (ru) * 2004-01-23 2009-05-12 Амген Инк Соединение, которое имеет активность ингибитора киназ, фармацевтическая композиция, которая включает указанное соединение, и их применение для приготовления лекарственного препарата
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives

Also Published As

Publication number Publication date
AP2007003950A0 (en) 2007-04-30
AU2005285157B2 (en) 2009-07-16
EP1789040A4 (en) 2009-09-02
PL1789040T3 (pl) 2016-04-29
JP2008512474A (ja) 2008-04-24
EA012606B1 (ru) 2009-10-30
CN101035531B (zh) 2013-01-02
WO2006031566A2 (en) 2006-03-23
BRPI0515089B1 (pt) 2019-07-16
ZA200702066B (en) 2008-08-27
CN101035531A (zh) 2007-09-12
AU2005285157A1 (en) 2006-03-23
US7645783B2 (en) 2010-01-12
WO2006031566A3 (en) 2006-06-08
US20080097106A1 (en) 2008-04-24
ES2559672T3 (es) 2016-02-15
KR101344984B1 (ko) 2013-12-24
KR20070052330A (ko) 2007-05-21
EP1789040B1 (en) 2015-12-23
RS54453B1 (sr) 2016-06-30
EA200700432A1 (ru) 2007-10-26
AP2451A (en) 2012-08-31
CA2580347A1 (en) 2006-03-23
HK1106139A1 (zh) 2008-03-07
BRPI0515089B8 (pt) 2021-05-25
US20080096941A1 (en) 2008-04-24
BRPI0515089A (pt) 2008-07-08
SI1789040T1 (sl) 2016-02-29
ME02370B (me) 2016-06-20
JP4998852B2 (ja) 2012-08-15
DK1789040T3 (en) 2016-02-01
US7550493B2 (en) 2009-06-23
US20060089396A1 (en) 2006-04-27
UA90864C2 (en) 2010-06-10
US7285567B2 (en) 2007-10-23
PT1789040E (pt) 2016-02-19
IL203061A (en) 2013-04-30
IL181849A (en) 2013-11-28
CY1118689T1 (el) 2017-07-12
MX2007002969A (es) 2008-02-15
EP1789040A2 (en) 2007-05-30
HRP20151439T1 (hr) 2016-02-12
IL181849A0 (en) 2007-07-04
CA2580347C (en) 2013-12-10

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