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HUE071193T2 - Sejtek transzfekció utáni korai izolálása (EPIC) biologikumok elõállításához - Google Patents

Sejtek transzfekció utáni korai izolálása (EPIC) biologikumok elõállításához

Info

Publication number
HUE071193T2
HUE071193T2 HUE16788603A HUE16788603A HUE071193T2 HU E071193 T2 HUE071193 T2 HU E071193T2 HU E16788603 A HUE16788603 A HU E16788603A HU E16788603 A HUE16788603 A HU E16788603A HU E071193 T2 HUE071193 T2 HU E071193T2
Authority
HU
Hungary
Prior art keywords
epic
biologics
cells
production
early post
Prior art date
Application number
HUE16788603A
Other languages
English (en)
Inventor
Victor Cairns
Christine Demaria
Jason Vitko
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of HUE071193T2 publication Critical patent/HUE071193T2/hu

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1086Preparation or screening of expression libraries, e.g. reporter assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70592CD52

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HUE16788603A 2015-10-09 2016-10-07 Sejtek transzfekció utáni korai izolálása (EPIC) biologikumok elõállításához HUE071193T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562239515P 2015-10-09 2015-10-09

Publications (1)

Publication Number Publication Date
HUE071193T2 true HUE071193T2 (hu) 2025-08-28

Family

ID=57211576

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE16788603A HUE071193T2 (hu) 2015-10-09 2016-10-07 Sejtek transzfekció utáni korai izolálása (EPIC) biologikumok elõállításához
HUE16788602A HUE069884T2 (hu) 2015-10-09 2016-10-07 Javított flare (áramlási citometriával csillapított reporter expresszió) technológia gyors tömeges válogatáshoz

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE16788602A HUE069884T2 (hu) 2015-10-09 2016-10-07 Javított flare (áramlási citometriával csillapított reporter expresszió) technológia gyors tömeges válogatáshoz

Country Status (12)

Country Link
US (4) US10317329B2 (hu)
EP (4) EP4530350A3 (hu)
CN (3) CN108368504B (hu)
AU (3) AU2016335699A1 (hu)
CA (2) CA3001364A1 (hu)
ES (2) ES3008383T3 (hu)
HU (2) HUE071193T2 (hu)
IL (4) IL309289A (hu)
MX (1) MX2018004366A (hu)
PL (2) PL3359665T3 (hu)
SG (3) SG10202111233SA (hu)
WO (2) WO2017062722A2 (hu)

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WO2016077689A1 (en) 2014-11-14 2016-05-19 Voyager Therapeutics, Inc. Modulatory polynucleotides
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EP3448874A4 (en) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
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BR112018073472A2 (pt) 2016-05-18 2019-08-27 Voyager Therapeutics Inc composições e métodos de tratamento da doença de huntington
CA3024448C (en) 2016-05-18 2025-09-09 Voyager Therapeutics, Inc. MODULATING POLYNUCLEOTIDES
CL2016001661A1 (es) 2016-06-29 2017-03-03 Univ Chile Promotor hibrido de ß-actina (de cricetulus griseus) y citomegalovirus (cmv), con región rica en dinucleótidos, citosina-guanina, vectores, líneas celulares, procedimiento para producir proteínas recombinantes.
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WO2018204786A1 (en) 2017-05-05 2018-11-08 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (als)
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CA3070087A1 (en) 2017-07-17 2019-01-24 Voyager Therapeutics, Inc. Trajectory array guide system
CA3075656A1 (en) 2017-09-29 2019-04-04 Voyager Therapeutics, Inc. Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery
WO2019079240A1 (en) 2017-10-16 2019-04-25 Voyager Therapeutics, Inc. TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
EP4454654A3 (en) 2017-10-16 2025-02-19 Voyager Therapeutics, Inc. Treatment of amyotrophic lateral sclerosis (als)
JP2021523914A (ja) 2018-05-15 2021-09-09 ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. パーキンソン病を治療するための組成物および方法
JP7528066B2 (ja) 2018-09-28 2024-08-05 ボイジャー セラピューティクス インコーポレイテッド 操作されたプロモータを有するフラタキシン発現コンストラクトおよびその使用方法
KR20230109683A (ko) 2020-11-19 2023-07-20 젠자임 코포레이션 유세포 분석 감쇠 리포터 발현(플레어) 다중 리포터 시스템 및 이의 사용 방법
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Also Published As

Publication number Publication date
CN116660127A (zh) 2023-08-29
HUE069884T2 (hu) 2025-04-28
US20230304913A1 (en) 2023-09-28
EP3359665A2 (en) 2018-08-15
EP4530350A2 (en) 2025-04-02
PL3359665T3 (pl) 2025-04-14
US20200018682A1 (en) 2020-01-16
ES3008383T3 (en) 2025-03-24
ES3024209T3 (en) 2025-06-04
CN108368504A (zh) 2018-08-03
PL3359666T3 (pl) 2025-06-23
AU2022275507A1 (en) 2023-02-02
CN108368504B (zh) 2022-07-19
EP3359665C0 (en) 2024-11-13
WO2017062722A3 (en) 2017-05-26
SG11201802823VA (en) 2018-05-30
US11635363B2 (en) 2023-04-25
MX2018004366A (es) 2018-08-01
CA3001238C (en) 2024-06-25
US20170121734A1 (en) 2017-05-04
EP3359666C0 (en) 2025-02-19
WO2017062724A1 (en) 2017-04-13
US20170227441A1 (en) 2017-08-10
CN108368505A (zh) 2018-08-03
WO2017062722A2 (en) 2017-04-13
EP3359666A1 (en) 2018-08-15
CA3001238A1 (en) 2017-04-13
AU2016335699A1 (en) 2018-05-24
SG10202111233SA (en) 2021-11-29
EP3359666B1 (en) 2025-02-19
CN108368505B (zh) 2023-02-21
IL258538B (en) 2022-12-01
IL258538A (en) 2018-05-31
EP4567425A3 (en) 2025-10-08
IL258537B1 (en) 2024-01-01
IL258538B2 (en) 2023-04-01
IL258537B2 (en) 2024-05-01
IL309289A (en) 2024-02-01
EP4530350A3 (en) 2025-06-25
IL258537A (en) 2018-05-31
EP4567425A2 (en) 2025-06-11
US10317329B2 (en) 2019-06-11
AU2022275507B2 (en) 2025-06-05
CA3001364A1 (en) 2017-04-13
IL297805A (en) 2022-12-01
AU2025226783A1 (en) 2025-09-25
HK1259493A1 (en) 2019-11-29
SG11201802829YA (en) 2018-05-30
EP3359665B1 (en) 2024-11-13

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