HUE059158T2 - Eljárás pridopidin elõállítására - Google Patents
Eljárás pridopidin elõállításáraInfo
- Publication number
- HUE059158T2 HUE059158T2 HUE16828644A HUE16828644A HUE059158T2 HU E059158 T2 HUE059158 T2 HU E059158T2 HU E16828644 A HUE16828644 A HU E16828644A HU E16828644 A HUE16828644 A HU E16828644A HU E059158 T2 HUE059158 T2 HU E059158T2
- Authority
- HU
- Hungary
- Prior art keywords
- pridopidine
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/24—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195756P | 2015-07-22 | 2015-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE059158T2 true HUE059158T2 (hu) | 2022-10-28 |
Family
ID=57834816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16828644A HUE059158T2 (hu) | 2015-07-22 | 2016-07-22 | Eljárás pridopidin elõállítására |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10047049B2 (hu) |
| EP (1) | EP3325443B1 (hu) |
| AR (2) | AR105434A1 (hu) |
| CA (1) | CA2993607C (hu) |
| DK (1) | DK3325443T3 (hu) |
| ES (1) | ES2922991T3 (hu) |
| HU (1) | HUE059158T2 (hu) |
| PL (1) | PL3325443T3 (hu) |
| TW (1) | TW201718491A (hu) |
| WO (1) | WO2017015609A1 (hu) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201390332A1 (ru) | 2010-09-03 | 2013-08-30 | Ивакс Интернэшнл Гмбх | Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов |
| MX347209B (es) | 2011-12-08 | 2017-04-19 | Teva Pharmaceuticals Int Gmbh | La sal de bromhidrato de pridopidina. |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| WO2014205229A1 (en) | 2013-06-21 | 2014-12-24 | IVAX International GmbH | Use of high dose pridopidine for treating huntington's disease |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| US9907786B2 (en) * | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US11471449B2 (en) | 2015-02-25 | 2022-10-18 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| EP3590512A1 (en) | 2015-02-25 | 2020-01-08 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to treat epilepsy |
| PL3419622T3 (pl) | 2016-02-24 | 2024-07-08 | Prilenia Neurotherapeutics Ltd. | Leczenie neurodegeneracyjnej choroby oczu przy użyciu pridopidyny |
| JP6912574B2 (ja) | 2016-08-24 | 2021-08-04 | プリレニア ニューロセラピューティクス リミテッド | 機能低下を治療するためのプリドピジンの使用 |
| BR112019003731A2 (pt) | 2016-08-24 | 2019-07-16 | Prilenia Therapeutics Dev Ltd | aplicação de pridopidina para tratamento de distonias |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| EP3357909A1 (en) * | 2017-02-02 | 2018-08-08 | Sandoz AG | Crystalline 4-[3-(methylsulfonyl)phenyl]-1-propyl-piperidine |
| EA202090510A1 (ru) | 2017-08-14 | 2020-06-08 | Приления Ньюротерапьютикс Лтд. | Способ лечения бокового амиотрофического склероза придопидином |
| WO2019046568A1 (en) | 2017-08-30 | 2019-03-07 | Teva Pharmaceuticals International Gmbh | DOSAGE FORMS WITH HIGH CONCENTRATION OF PRIDOPIDINE |
| MX383462B (es) | 2017-09-08 | 2025-03-14 | Prilenia Neurotherapeutics Ltd | Pridopidina para el tratamiento de las discinesias inducidas por fármacos |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| US12357624B2 (en) | 2019-02-04 | 2025-07-15 | Prilenia Neurotherapeutics Ltd. | Low dose pridopidine for Parkinson's Disease and other diseases associated with parkinsonism |
| JP7701931B2 (ja) | 2020-02-13 | 2025-07-02 | プリレニア ニューロセラピューティクス リミテッド | プリドピジンおよび他の活性薬剤を使用して筋萎縮性側索を治療するための併用療法 |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
| US20250250233A1 (en) * | 2022-05-03 | 2025-08-07 | Prilenia Neurotherapeutics Ltd. | Processes and intermediates for the preparation of pridopidine |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3176063B2 (ja) | 1991-04-17 | 2001-06-11 | ファルマシア・アンド・アップジョン・カンパニー | 新規中枢神経作用性置換フェニルアザシクロアルカン類 |
| SE9702716D0 (sv) | 1997-07-15 | 1997-07-15 | Ross Nicholas Waters | Substituted phenylazacycloalkanes in the treatment of cognitive disorders |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| AU2005293754B2 (en) * | 2004-10-13 | 2011-07-21 | Teva Pharmaceuticals International Gmbh | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-N-propyl-piperidine |
| MX2007004216A (es) | 2004-10-13 | 2007-10-10 | Neurosearch Sweden Ab | Proceso para la sintesis de 4-(3-sulfonil)-piperidinas. |
| BRPI0810161A2 (pt) | 2007-04-12 | 2014-12-30 | Nsab Af Neurosearch Sweden Ab | Composto, preparação farmacêutica, composição farmacêutica, e, uso de um composto |
| WO2011107583A1 (en) | 2010-03-04 | 2011-09-09 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders |
| EA201390332A1 (ru) | 2010-09-03 | 2013-08-30 | Ивакс Интернэшнл Гмбх | Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов |
| EP2753603B1 (en) * | 2011-09-07 | 2017-06-21 | Teva Pharmaceuticals International GmbH | Polymorphic form of pridopidine hydrochloride |
| MX347209B (es) | 2011-12-08 | 2017-04-19 | Teva Pharmaceuticals Int Gmbh | La sal de bromhidrato de pridopidina. |
| EA027748B1 (ru) | 2012-04-04 | 2017-08-31 | Тева Фармасьютикалз Интернэшнл Гмбх | Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения |
| CA2884260A1 (en) | 2012-09-27 | 2014-04-03 | Teva Pharmaceutical Industries Ltd. | Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| AU2013323131A1 (en) | 2012-09-27 | 2015-05-07 | Teva Pharmaceutical Industries Ltd. | Laquinimod and pridopidine for treating neurodegenerative disorders |
| WO2014205229A1 (en) | 2013-06-21 | 2014-12-24 | IVAX International GmbH | Use of high dose pridopidine for treating huntington's disease |
| HUE058288T2 (hu) | 2014-01-22 | 2022-07-28 | Prilenia Neurotherapeutics Ltd | Pridopidin módosított hatóanyag-leadású készítményei |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| EP3236964A4 (en) | 2014-12-22 | 2018-09-19 | Teva Pharmaceuticals International GmbH | L-tartrate salt of pridopidine |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| EP3590512A1 (en) | 2015-02-25 | 2020-01-08 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to treat epilepsy |
| CA2993183A1 (en) | 2015-07-22 | 2017-01-26 | Teva Pharmaceuticals International Gmbh | Pridopidine base formulations and their use |
-
2016
- 2016-07-21 AR ARP160102219A patent/AR105434A1/es active IP Right Grant
- 2016-07-22 US US15/217,683 patent/US10047049B2/en active Active
- 2016-07-22 TW TW105123329A patent/TW201718491A/zh unknown
- 2016-07-22 ES ES16828644T patent/ES2922991T3/es active Active
- 2016-07-22 DK DK16828644.1T patent/DK3325443T3/da active
- 2016-07-22 WO PCT/US2016/043682 patent/WO2017015609A1/en not_active Ceased
- 2016-07-22 HU HUE16828644A patent/HUE059158T2/hu unknown
- 2016-07-22 EP EP16828644.1A patent/EP3325443B1/en active Active
- 2016-07-22 CA CA2993607A patent/CA2993607C/en active Active
- 2016-07-22 PL PL16828644.1T patent/PL3325443T3/pl unknown
-
2024
- 2024-08-14 AR ARP240102151A patent/AR133546A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2993607A1 (en) | 2017-01-26 |
| TW201718491A (zh) | 2017-06-01 |
| ES2922991T3 (es) | 2022-09-22 |
| EP3325443A4 (en) | 2019-01-16 |
| US20170022158A1 (en) | 2017-01-26 |
| EP3325443A1 (en) | 2018-05-30 |
| PL3325443T3 (pl) | 2022-08-01 |
| AR133546A2 (es) | 2025-10-08 |
| EP3325443B1 (en) | 2022-06-08 |
| WO2017015609A1 (en) | 2017-01-26 |
| DK3325443T3 (da) | 2022-07-18 |
| US10047049B2 (en) | 2018-08-14 |
| AR105434A1 (es) | 2017-10-04 |
| CA2993607C (en) | 2024-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE059158T2 (hu) | Eljárás pridopidin elõállítására | |
| IL264143B (en) | Processes for preparing olaparib | |
| HUE064612T2 (hu) | Eljárás brivaracetam elõállítására | |
| DK3096741T3 (da) | Fremgangsmåde til fremstillingen af hybridosomer | |
| HUE042409T2 (hu) | Eljárás diaril-tiohidantoin vegyület elõállítására | |
| DK3174858T3 (da) | Fremgangsmåde til fremstilling af pyrazoler | |
| DK3453721T3 (da) | Process of manufacture of annexin v | |
| HUE050974T2 (hu) | Eljárás pirimidinszulfamid-származékok elõállítására | |
| HUE058257T2 (hu) | Eljárások oxatiazin-jellegû vegyületek elõállítására | |
| DK3341479T3 (da) | LNA-G-Proces | |
| HUE057118T2 (hu) | Folyamat | |
| DK3359522T3 (da) | Proces til fremstilling af N-Boc-bifenylalaninol | |
| ZA201706795B (en) | Process for the preparation of dicycloplatin | |
| DK3166611T3 (da) | Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxypicolinsyrer | |
| HUE055463T2 (hu) | Eljárás glükopiranozil-szubsztituált benzil-benzol-származékok elõállítására | |
| HUE049170T2 (hu) | Eljárás szubsztituált cikloszerinek elõállítására | |
| HUE042349T2 (hu) | Eljárás diariltiohidantoin vegyület elõállítására | |
| HUE053428T2 (hu) | Eljárás otikus progenitorok elõállítására | |
| HUE045704T2 (hu) | Eljárás 5-fluor-1H-pirazolok elõállítására hexafluorpropénbõl kiindulva | |
| HUE047756T2 (hu) | Eljárás metil-merkaptán elõállítására | |
| HUE054584T2 (hu) | Maropitant készítmény | |
| HUE045746T2 (hu) | Eljárás fûszerkészítmények elõállítására | |
| HRP20181805T1 (hr) | Postupak za proizvodnju poligvanidina | |
| BR112016019246A2 (pt) | processo paraa fabricação de hidroclorofluoro-olefinas | |
| EP3523659C0 (en) | MULTI-PROTEASE PROCESS |