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HUE063840T2 - TGF-béta receptor II típusú fúziós proteinek és azok felhasználásai - Google Patents

TGF-béta receptor II típusú fúziós proteinek és azok felhasználásai

Info

Publication number
HUE063840T2
HUE063840T2 HUE18794202A HUE18794202A HUE063840T2 HU E063840 T2 HUE063840 T2 HU E063840T2 HU E18794202 A HUE18794202 A HU E18794202A HU E18794202 A HUE18794202 A HU E18794202A HU E063840 T2 HUE063840 T2 HU E063840T2
Authority
HU
Hungary
Prior art keywords
tgf
fusion proteins
receptor type
beta receptor
beta
Prior art date
Application number
HUE18794202A
Other languages
English (en)
Inventor
Ravindra Kumar
Dianne S Sako
Original Assignee
Acceleron Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acceleron Pharma Inc filed Critical Acceleron Pharma Inc
Publication of HUE063840T2 publication Critical patent/HUE063840T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
HUE18794202A 2017-05-04 2018-05-03 TGF-béta receptor II típusú fúziós proteinek és azok felhasználásai HUE063840T2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762501229P 2017-05-04 2017-05-04
US201762510422P 2017-05-24 2017-05-24
US201762578674P 2017-10-30 2017-10-30

Publications (1)

Publication Number Publication Date
HUE063840T2 true HUE063840T2 (hu) 2024-02-28

Family

ID=64016255

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18794202A HUE063840T2 (hu) 2017-05-04 2018-05-03 TGF-béta receptor II típusú fúziós proteinek és azok felhasználásai

Country Status (21)

Country Link
US (3) US11021527B2 (hu)
EP (2) EP3628049B1 (hu)
JP (2) JP7267664B2 (hu)
KR (2) KR102635723B1 (hu)
CN (2) CN110785431B (hu)
AU (3) AU2018261131A1 (hu)
BR (1) BR112019023071A2 (hu)
CA (1) CA3061472A1 (hu)
CY (1) CY1126121T1 (hu)
DK (1) DK3628049T3 (hu)
ES (1) ES2948647T3 (hu)
FI (1) FI3628049T3 (hu)
HR (1) HRP20230706T1 (hu)
HU (1) HUE063840T2 (hu)
LT (1) LT3628049T (hu)
MD (1) MD3628049T2 (hu)
PL (1) PL3628049T3 (hu)
PT (1) PT3628049T (hu)
RS (1) RS64315B1 (hu)
SI (1) SI3628049T1 (hu)
WO (1) WO2018204594A1 (hu)

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WO2021218883A1 (zh) * 2020-04-28 2021-11-04 神州细胞工程有限公司 一种TGFβR2胞外区截短分子、其与抗EGFR抗体的融合蛋白及其抗肿瘤用途
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Also Published As

Publication number Publication date
EP4241848A2 (en) 2023-09-13
CN110785431A (zh) 2020-02-11
EP3628049A4 (en) 2021-01-13
US20210324040A1 (en) 2021-10-21
US20180327477A1 (en) 2018-11-15
US20250109184A1 (en) 2025-04-03
LT3628049T (lt) 2023-08-25
US11021527B2 (en) 2021-06-01
JP7267664B2 (ja) 2023-05-02
DK3628049T3 (da) 2023-08-14
AU2023200218B2 (en) 2024-08-15
CN110785431B (zh) 2024-05-07
CA3061472A1 (en) 2018-11-08
MD3628049T2 (ro) 2023-10-31
PT3628049T (pt) 2023-07-03
KR20200003873A (ko) 2020-01-10
BR112019023071A2 (pt) 2020-06-09
FI3628049T3 (fi) 2023-07-26
AU2024205045A1 (en) 2024-08-08
AU2018261131A1 (en) 2019-11-07
EP4241848A3 (en) 2023-11-01
KR102635723B1 (ko) 2024-02-08
RS64315B1 (sr) 2023-08-31
EP3628049B1 (en) 2023-05-10
US12195519B2 (en) 2025-01-14
JP2020518246A (ja) 2020-06-25
KR20240023201A (ko) 2024-02-20
JP2023055827A (ja) 2023-04-18
SI3628049T1 (sl) 2023-10-30
HRP20230706T1 (hr) 2023-10-13
EP3628049A1 (en) 2020-04-01
PL3628049T3 (pl) 2023-09-25
CN118406157A (zh) 2024-07-30
ES2948647T3 (es) 2023-09-15
CY1126121T1 (el) 2023-11-15
AU2023200218A1 (en) 2023-02-16
WO2018204594A1 (en) 2018-11-08

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