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HRP20080187T3 - Derivati arilpiperazina i njihova upotreba kao selektivnih liganada za dopaminski receptor d3 - Google Patents

Derivati arilpiperazina i njihova upotreba kao selektivnih liganada za dopaminski receptor d3

Info

Publication number
HRP20080187T3
HRP20080187T3 HR20080187T HRP20080187T HRP20080187T3 HR P20080187 T3 HRP20080187 T3 HR P20080187T3 HR 20080187 T HR20080187 T HR 20080187T HR P20080187 T HRP20080187 T HR P20080187T HR P20080187 T3 HRP20080187 T3 HR P20080187T3
Authority
HR
Croatia
Prior art keywords
alkyl
polyfluoroalkylsulfanyl
monofluoroalkyl
polyfluoroalkoxy
polyfluoroalkyl
Prior art date
Application number
HR20080187T
Other languages
English (en)
Croatian (hr)
Inventor
Capet Marc
Danvy Denis
Dartois Catherine
Levoin Nicolas
Morvan Marcel
Berrebi-Bertrand Isabelle
Calmels Thierry
Robert Philippe
Schwartz Jean-Charles
Lecomte Jeanne-Marie
Original Assignee
Bioprojet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet filed Critical Bioprojet
Publication of HRP20080187T3 publication Critical patent/HRP20080187T3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20080187T 2004-12-01 2005-11-29 Derivati arilpiperazina i njihova upotreba kao selektivnih liganada za dopaminski receptor d3 HRP20080187T3 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0412763A FR2878524B1 (fr) 2004-12-01 2004-12-01 Nouveaux derives d'arylpiperazine
PCT/FR2005/002964 WO2006058993A1 (fr) 2004-12-01 2005-11-29 Derives d’arylpiperazine et leur utilisation comme ligands selectifs du recepteur d3 de la dopamine

Publications (1)

Publication Number Publication Date
HRP20080187T3 true HRP20080187T3 (hr) 2008-05-31

Family

ID=34951009

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20080187T HRP20080187T3 (hr) 2004-12-01 2005-11-29 Derivati arilpiperazina i njihova upotreba kao selektivnih liganada za dopaminski receptor d3

Country Status (12)

Country Link
US (1) US20080214542A1 (xx)
EP (1) EP1828125B1 (xx)
AT (1) ATE391711T1 (xx)
DE (1) DE602005006018T2 (xx)
DK (1) DK1828125T3 (xx)
ES (1) ES2302254T3 (xx)
FR (1) FR2878524B1 (xx)
HR (1) HRP20080187T3 (xx)
PL (1) PL1828125T3 (xx)
PT (1) PT1828125E (xx)
SI (1) SI1828125T1 (xx)
WO (1) WO2006058993A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ555491A (en) * 2005-01-03 2010-01-29 Univ Siena Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
EP1870405A1 (en) * 2006-06-22 2007-12-26 Bioprojet Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands
WO2009095438A1 (en) * 2008-02-01 2009-08-06 Neurosearch A/S Novel aryl piperazine derivatives useful as modulators of dopamine and serotonin receptors
EP2257531A1 (en) * 2008-03-14 2010-12-08 NeuroSearch A/S Novel quinolinylamide derivatives useful as modulators of dopamine and serotonin receptors
US9227944B2 (en) 2008-10-10 2016-01-05 Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China Dopamine D3 receptor ligands and preparation and medical uses of the same
JP5701213B2 (ja) 2008-10-10 2015-04-15 インスティチュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ 新規なドーパミンｄ３受容体リガンド、その調製及び使用
WO2014079504A1 (en) * 2012-11-22 2014-05-30 Biofordrug S.R.L. Polycyclic ligands of 5-ht7 receptor and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2141791A1 (en) * 1992-08-06 1994-02-17 Geoffrey Stemp 5-(2-oxyphenyl)-pyrrole derivatives as dopamine d3 receptor antagonists
US5523229A (en) * 1994-03-22 1996-06-04 Trustees Of The University Of Pennsylvania Antibodies specific for oncofetal fibronectin
TR200201690T2 (tr) * 1999-12-30 2002-11-21 H. Lundbeck A/S 4-Fenil-1-piperazinil,-piperidinil ve -tetrahidropiridil türevleri
CA2475783A1 (en) * 2002-02-13 2003-08-21 Glaxo Group Limited Benzenesulfonamide derivatives as antipsychotic agents
US20040204422A1 (en) * 2003-04-14 2004-10-14 Abbott Gmbh & Co. Kg. N-[(Piperazinyl)hetaryl]arylsulfonamide compounds

Also Published As

Publication number Publication date
SI1828125T1 (sl) 2008-08-31
ES2302254T3 (es) 2008-07-01
DK1828125T3 (da) 2008-08-04
DE602005006018D1 (de) 2008-05-21
DE602005006018T2 (de) 2008-07-10
FR2878524B1 (fr) 2007-01-19
PL1828125T3 (pl) 2008-09-30
WO2006058993A1 (fr) 2006-06-08
EP1828125A1 (fr) 2007-09-05
PT1828125E (pt) 2008-08-22
FR2878524A1 (fr) 2006-06-02
ATE391711T1 (de) 2008-04-15
EP1828125B1 (fr) 2008-04-09
US20080214542A1 (en) 2008-09-04

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