HK1203840A1 - Pharmaceutical composition and administration thereof - Google Patents
Pharmaceutical composition and administration thereof Download PDFInfo
- Publication number
- HK1203840A1 HK1203840A1 HK15104628.5A HK15104628A HK1203840A1 HK 1203840 A1 HK1203840 A1 HK 1203840A1 HK 15104628 A HK15104628 A HK 15104628A HK 1203840 A1 HK1203840 A1 HK 1203840A1
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- HK
- Hong Kong
- Prior art keywords
- pharmaceutical composition
- weight
- amorphous compound
- solid dispersion
- compound
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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| EP2872122A1 (en) | 2012-07-16 | 2015-05-20 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of (r)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration thereof |
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| WO2019200246A1 (en) | 2018-04-13 | 2019-10-17 | Alexander Russell Abela | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
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