GT201000095A - Producto de dispersión sólida que contiene un compuesto a base de n-aril urea - Google Patents
Producto de dispersión sólida que contiene un compuesto a base de n-aril ureaInfo
- Publication number
- GT201000095A GT201000095A GT201000095A GT201000095A GT201000095A GT 201000095 A GT201000095 A GT 201000095A GT 201000095 A GT201000095 A GT 201000095A GT 201000095 A GT201000095 A GT 201000095A GT 201000095 A GT201000095 A GT 201000095A
- Authority
- GT
- Guatemala
- Prior art keywords
- aril
- urea
- solid dispersion
- based compound
- product containing
- Prior art date
Links
- 239000007962 solid dispersion Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UN PRODUCTO QUE COMPRENDE AL MENOS UN AGENTE FARMACÉUTICAMENTE ACTIVO A BASE DE N-ARIL UREA O UN AGENTE DE ESTRUCTURA RELACIONADA QUE ES OBTENIDO MEDIANTE A) LA PREPARACIÓN DE UNA MEZCLA LÍQUIDA QUE CONTIENE AL MENOS UN AGENTE ACTIVO, UN AGENTE FORMADOR DE MATRIZ ACEPTABLE PARA USO FARMACÉUTICO Y B) LA ELIMINACIÓN DEL O DE LOS SOLVENTES DE LA MEZCLA LÍQUIDA PARA OBTENER EL PRODUCTO DE DISPERSIÓN SÓLIDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99961307P | 2007-10-19 | 2007-10-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT201000095A true GT201000095A (es) | 2012-04-03 |
Family
ID=40089072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT201000095A GT201000095A (es) | 2007-10-19 | 2010-04-15 | Producto de dispersión sólida que contiene un compuesto a base de n-aril urea |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090143423A1 (es) |
| EP (1) | EP2197426A2 (es) |
| JP (1) | JP2011500647A (es) |
| KR (1) | KR20100090689A (es) |
| CN (1) | CN101827585A (es) |
| AR (1) | AR068916A1 (es) |
| AU (1) | AU2008313620A1 (es) |
| BR (1) | BRPI0818339A2 (es) |
| CA (1) | CA2699335A1 (es) |
| CL (1) | CL2008003092A1 (es) |
| CO (1) | CO6270303A2 (es) |
| CR (1) | CR11441A (es) |
| DO (1) | DOP2010000114A (es) |
| EC (1) | ECSP10010184A (es) |
| GT (1) | GT201000095A (es) |
| MX (1) | MX2010004292A (es) |
| PE (1) | PE20091041A1 (es) |
| RU (1) | RU2010119924A (es) |
| TW (1) | TW200922549A (es) |
| UA (1) | UA100866C2 (es) |
| UY (1) | UY31406A1 (es) |
| WO (1) | WO2009050289A2 (es) |
| ZA (1) | ZA201002130B (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201020236A (en) * | 2008-10-17 | 2010-06-01 | Abbott Lab | TRPV1 antagonists |
| EP2352727A1 (en) * | 2008-10-17 | 2011-08-10 | Abbott Laboratories | Trpv1 antagonists |
| US20100210682A1 (en) * | 2009-02-19 | 2010-08-19 | Abbott Laboratories | Repeated Dosing of TRPV1 Antagonists |
| US20120168987A1 (en) * | 2009-09-18 | 2012-07-05 | Basf Se | Method For Producing Preparations Of Substances With Low Solubility In Water |
| CA2821659C (en) * | 2010-12-23 | 2019-05-14 | Abbott Gmbh & Co. Kg | Solid retard formulations based on solid dispersions |
| WO2012096859A2 (en) | 2011-01-10 | 2012-07-19 | Celgene Corporation | Oral dosage forms of cyclopropanecarboxylic acid {2-[(1s)-1-(3-ethoxy-4-methoxy-phenyl]-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1h-isoindol-4-yl}-amide |
| HK1201186A1 (en) * | 2011-12-29 | 2015-08-28 | Abbvie Inc. | Solid compositions comprising an hcv inhibitor |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
| EA029081B9 (ru) | 2013-01-31 | 2018-09-28 | Джилид Фармассет Ллс | Комбинированный состав двух противовирусных соединений |
| JP6130585B2 (ja) | 2013-03-15 | 2017-05-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 無定形状態のhcv阻害薬の固体経口投薬製剤 |
| ES2694662T3 (es) | 2013-07-03 | 2018-12-26 | Lts Lohmann Therapie-Systeme Ag | Sistema terapéutico transdérmico con componente electrónico |
| PL3038601T3 (pl) | 2013-08-27 | 2020-08-24 | Gilead Pharmasset Llc | Formulacja złożona dwóch związków przeciwwirusowych |
| CN106456567A (zh) | 2014-05-20 | 2017-02-22 | Lts勒曼治疗系统股份公司 | 在经皮递送系统中调节活性剂释放的方法 |
| ES2954087T3 (es) | 2014-05-20 | 2023-11-20 | Lts Lohmann Therapie Systeme Ag | Sistema de administración transdérmica que incluye un mediador de interfase |
| WO2015177204A1 (en) | 2014-05-20 | 2015-11-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
| CA2987867C (en) | 2015-06-09 | 2023-06-27 | Capsugel Belgium Nv | Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules |
| US12186314B2 (en) * | 2015-12-22 | 2025-01-07 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treatment, amelioration, and prevention of anesthesia-induced hypothermia |
| CN112955130A (zh) * | 2018-10-30 | 2021-06-11 | 佩洛通治疗公司 | 包含取代茚满的固体分散体和药物组合物及其制备和使用方法 |
| WO2021039023A1 (ja) | 2019-08-23 | 2021-03-04 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
| KR20250166332A (ko) | 2019-08-23 | 2025-11-27 | 모찌다 세이야쿠 가부시끼가이샤 | 헤테로시클리덴아세트아미드 유도체의 제조 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362878A (en) * | 1991-03-21 | 1994-11-08 | Pfizer Inc. | Intermediates for making N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) |
| RU94046149A (ru) * | 1992-05-28 | 1996-11-27 | Пфайзер Инк. (US) | Новые n-арил и n-гетероарил производные мочевины как ингибиторы ацил кофермента а:холестерин ацил трансферазы (асат) фармацевтическая композиция, способ ингибирования (асат) |
| EP1015046A2 (en) * | 1998-07-14 | 2000-07-05 | Em Industries, Inc. | Microdisperse drug delivery systems |
| US7015233B2 (en) * | 2003-06-12 | 2006-03-21 | Abbott Laboratories | Fused compounds that inhibit vanilloid subtype 1 (VR1) receptor |
| AR049297A1 (es) * | 2004-06-08 | 2006-07-12 | Vertex Pharma | Una composicion farmaceutica y dispersiones solidas de vx-950 (inhibidor de la proteasa de hcv ns3/4a) y proceso de obtencion |
| EP1796642B1 (en) * | 2004-08-27 | 2008-05-21 | Bayer Pharmaceuticals Corporation | Pharmaceutical compositions in the form of solid dispersions for the treatment of cancer |
| KR20080042039A (ko) * | 2005-04-18 | 2008-05-14 | 루비콘 리서치 피브이티. 엘티디. | 생물학적으로 강화된 조성물 |
| KR100715355B1 (ko) * | 2005-09-30 | 2007-05-07 | 주식회사유한양행 | 프란루카스트를 함유하는 분무-건조 과립 및 그의 제조방법 |
| EP1959926A1 (en) * | 2005-10-25 | 2008-08-27 | Abbott Laboratories | Formulation comprising a drug of low water solubility and method of use thereof |
| WO2007066189A2 (en) * | 2005-12-09 | 2007-06-14 | Pfizer Products Inc. | Salts, prodrugs and formulations of 1-[5-(4-amino-7-isopropyl-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-2-methoxy-phenyl]-3-(2,4-dichloro-phenyl)-urea |
| US7745448B2 (en) * | 2005-12-28 | 2010-06-29 | Abbott Laboratories Inc. | Crystalline N-(4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl)-N′-(2-fluoro-5-(trifluoromethyl)phenyl)urea ethanolate |
| WO2007092642A2 (en) * | 2006-02-09 | 2007-08-16 | Merck & Co., Inc. | Polymer formulations of cetp inhibitors |
-
2008
- 2008-10-17 JP JP2010529406A patent/JP2011500647A/ja active Pending
- 2008-10-17 UA UAA201006030A patent/UA100866C2/ru unknown
- 2008-10-17 AU AU2008313620A patent/AU2008313620A1/en not_active Abandoned
- 2008-10-17 CA CA2699335A patent/CA2699335A1/en not_active Abandoned
- 2008-10-17 UY UY31406A patent/UY31406A1/es not_active Application Discontinuation
- 2008-10-17 CN CN200880112161A patent/CN101827585A/zh active Pending
- 2008-10-17 CL CL2008003092A patent/CL2008003092A1/es unknown
- 2008-10-17 PE PE2008001785A patent/PE20091041A1/es not_active Application Discontinuation
- 2008-10-17 RU RU2010119924/15A patent/RU2010119924A/ru not_active Application Discontinuation
- 2008-10-17 EP EP08840773A patent/EP2197426A2/en not_active Withdrawn
- 2008-10-17 KR KR1020107010874A patent/KR20100090689A/ko not_active Withdrawn
- 2008-10-17 US US12/253,499 patent/US20090143423A1/en not_active Abandoned
- 2008-10-17 BR BRPI0818339 patent/BRPI0818339A2/pt not_active IP Right Cessation
- 2008-10-17 TW TW097140229A patent/TW200922549A/zh unknown
- 2008-10-17 AR ARP080104542A patent/AR068916A1/es not_active Application Discontinuation
- 2008-10-17 MX MX2010004292A patent/MX2010004292A/es not_active Application Discontinuation
- 2008-10-17 WO PCT/EP2008/064073 patent/WO2009050289A2/en not_active Ceased
-
2010
- 2010-03-25 ZA ZA2010/02130A patent/ZA201002130B/en unknown
- 2010-04-15 GT GT201000095A patent/GT201000095A/es unknown
- 2010-04-16 DO DO2010000114A patent/DOP2010000114A/es unknown
- 2010-04-27 CO CO10049270A patent/CO6270303A2/es not_active Application Discontinuation
- 2010-05-17 EC EC2010010184A patent/ECSP10010184A/es unknown
- 2010-05-19 CR CR11441A patent/CR11441A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW200922549A (en) | 2009-06-01 |
| PE20091041A1 (es) | 2009-08-22 |
| WO2009050289A2 (en) | 2009-04-23 |
| CO6270303A2 (es) | 2011-04-20 |
| ECSP10010184A (es) | 2010-06-29 |
| CL2008003092A1 (es) | 2009-11-27 |
| MX2010004292A (es) | 2010-08-02 |
| UA100866C2 (ru) | 2013-02-11 |
| BRPI0818339A2 (pt) | 2015-04-22 |
| AU2008313620A1 (en) | 2009-04-23 |
| UY31406A1 (es) | 2009-05-29 |
| US20090143423A1 (en) | 2009-06-04 |
| ZA201002130B (en) | 2011-11-30 |
| WO2009050289A3 (en) | 2010-03-25 |
| DOP2010000114A (es) | 2010-05-15 |
| RU2010119924A (ru) | 2011-11-27 |
| CA2699335A1 (en) | 2009-04-23 |
| KR20100090689A (ko) | 2010-08-16 |
| CN101827585A (zh) | 2010-09-08 |
| JP2011500647A (ja) | 2011-01-06 |
| EP2197426A2 (en) | 2010-06-23 |
| AR068916A1 (es) | 2009-12-16 |
| CR11441A (es) | 2010-10-25 |
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