[go: up one dir, main page]

GT200600314A - Complejos metalicos con contenido de perfluroalquilo, procedimientos para su preparacion, asi como su uso. - Google Patents

Complejos metalicos con contenido de perfluroalquilo, procedimientos para su preparacion, asi como su uso.

Info

Publication number
GT200600314A
GT200600314A GT200600314A GT200600314A GT200600314A GT 200600314 A GT200600314 A GT 200600314A GT 200600314 A GT200600314 A GT 200600314A GT 200600314 A GT200600314 A GT 200600314A GT 200600314 A GT200600314 A GT 200600314A
Authority
GT
Guatemala
Prior art keywords
procedures
preparation
content
perfluroalquilo
well
Prior art date
Application number
GT200600314A
Other languages
English (en)
Inventor
Heiko Schirmer
Hanns-Joachim Weinmann
Johannes Platzek
Ludwing Zorn
Bernd Misselwitz
Jorg Meding
Heribert Schmitt-Willich
Thomas Brumby
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102005033903A external-priority patent/DE102005033903B4/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of GT200600314A publication Critical patent/GT200600314A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

ESTA INVENCIÓN SE REFIERE A LOS COMPUESTOS METÁLICOS CON CONTENIDO DE PERFLUOROALQUILO CON GRUPO N-ALQUILO DE LA FÓRMULA GENERAL (I), A PROCEDIMIENTOS PARA SU PREPARACIÓN Y A SU USO EN EL DIAGNÓSTICO POR RMN, RAYOS X, RADIODIAGNÓSTICO, RADIOTERAPIA Y LINFOGRAFÍA MRT. T2006
GT200600314A 2005-07-15 2006-07-14 Complejos metalicos con contenido de perfluroalquilo, procedimientos para su preparacion, asi como su uso. GT200600314A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005033903A DE102005033903B4 (de) 2005-07-15 2005-07-15 Perfluoralkylhaltige Komplexe, Verfahren zu deren Herstellung, sowie deren Verwendung und diese enthaltende pharmazeutische Mittel
EP05090230 2005-08-10

Publications (1)

Publication Number Publication Date
GT200600314A true GT200600314A (es) 2007-07-05

Family

ID=38813200

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200600314A GT200600314A (es) 2005-07-15 2006-07-14 Complejos metalicos con contenido de perfluroalquilo, procedimientos para su preparacion, asi como su uso.

Country Status (10)

Country Link
US (1) US20070020183A1 (es)
EP (1) EP1904462A2 (es)
JP (1) JP2009509915A (es)
CA (1) CA2615434A1 (es)
DO (1) DOP2006000166A (es)
GT (1) GT200600314A (es)
PE (1) PE20070363A1 (es)
TW (1) TW200740777A (es)
UY (1) UY29663A1 (es)
WO (1) WO2007009637A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7618957B2 (en) * 2005-07-15 2009-11-17 Bayer Schering Pharma Aktiengesellschaft Perfluoroalkyl-containing complexes, process for their production as well as their use
DE102007015598A1 (de) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Verwendung von fluorhaltigen Verbindungen zu Diagnosezwecken mit Hilfe bildgebender Verfahren
US7810965B2 (en) 2008-03-02 2010-10-12 Lumenetix, Inc. Heat removal system and method for light emitting diode lighting apparatus
US7969075B2 (en) 2009-02-10 2011-06-28 Lumenetix, Inc. Thermal storage system using encapsulated phase change materials in LED lamps
US8760265B2 (en) * 2009-05-08 2014-06-24 Apple Inc. Remote control signal learning and processing by a host device and accessory
CN105189448B (zh) * 2013-05-09 2017-05-24 佳能株式会社 化合物，光固化性组合物，和通过使用所述光固化性组合物的图案化膜、光学组件、电路板、电子组件的制造方法，和固化物
BR112019023249A8 (pt) 2017-05-05 2021-02-23 Centre For Probe Dev And Commercialization anticorpos monoclonais igf-1r e usos dos mesmos
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
IL270453B2 (en) 2017-05-05 2025-05-01 Fusion Pharmaceuticals Inc Pharmacokinetic enhancements of bifunctional chelates and uses thereof
SE543911C2 (en) 2020-01-14 2021-09-21 A & R Carton Lund Ab An expansible press plunger, an attachment unit for attaching a container element in a container body and a method for attaching a container element in a container body
CN114181164A (zh) * 2021-12-13 2022-03-15 武汉大学中南医院 基于Fe(Ⅱ)特异性MRI对比剂的合成方法及其应用
CN114085619B (zh) * 2021-12-23 2022-07-15 泰州亚德胶粘制品有限公司 一种耐高温低粘着光学胶粘剂及其制备方法
CN115308319A (zh) * 2022-06-28 2022-11-08 北京大学 一种全氟及多氟烷基化合物非靶向筛查的定量方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10040381C1 (de) * 2000-08-11 2002-06-06 Schering Ag Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung
US6641797B2 (en) * 2000-08-11 2003-11-04 Schering Aktiengesellschaft Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung
US6676928B2 (en) * 2000-08-11 2004-01-13 Schering Aktiengesellschaft Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use
US6818203B2 (en) * 2000-08-11 2004-11-16 Schering Aktiengesellschaft Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses
US7334704B1 (en) * 2005-01-25 2008-02-26 William C Bynum Apparatus for flattening the walls of flexible tubes
US7618957B2 (en) * 2005-07-15 2009-11-17 Bayer Schering Pharma Aktiengesellschaft Perfluoroalkyl-containing complexes, process for their production as well as their use

Also Published As

Publication number Publication date
EP1904462A2 (de) 2008-04-02
UY29663A1 (es) 2007-02-28
DOP2006000166A (es) 2007-02-28
CA2615434A1 (en) 2007-01-25
JP2009509915A (ja) 2009-03-12
TW200740777A (en) 2007-11-01
WO2007009637A3 (de) 2007-05-10
PE20070363A1 (es) 2007-04-20
WO2007009637A2 (de) 2007-01-25
US20070020183A1 (en) 2007-01-25

Similar Documents

Publication Publication Date Title
CO6321189A2 (es) Compuestos de tiazol y oxazol de bencen-sulfonamida
DOP2011000171A (es) Compuestos organico
GT200600314A (es) Complejos metalicos con contenido de perfluroalquilo, procedimientos para su preparacion, asi como su uso.
CR9786A (es) Compuestos de bencimidazol-tiofeno
CL2012000707A1 (es) Compuestos derivados de [5-(pirrolo[1,2-c][1.2.3]triazin-7-il)tetrahidrofuran-2-il]metanol; composición farmacéutica; y su uso para el tratamiento de la hepatitis c.
ECSP077302A (es) 6H-[1]BENZOPIRANO[4,3-b]QUlNOLINAS, Y SU USO COMO AGENTES ESTROGENICOS
CL2007000311A1 (es) Compuestos derivados de cromen-2-ona; composicion farmaceutica que los comprende;y su uso en el trastamiento de un trastorno proliferativos como es el cancer.
MX2007008457A (es) Eter n, n, n'-trimetil-bis-(aminoetilico) y sus derivados como catalizadores para poliuretanos.
CR11861A (es) Compuestos organicos
DOP2011000199A (es) Compuestos heterociclocos y metodos de uso
GT200500275A (es) Nuevos herbicidas
CR10694A (es) Compuestos antagonistas del receptor de glucagon, composiciones que contienen dichos compuestos y procedimientos de uso
GT200600264A (es) Modificaciones cristalinas de piraclostrobina
UY31038A1 (es) Compuestos
ZA200702700B (en) Diagnostic compounds
UY32659A (es) Pirazinilpirazoles
HN2006011218A (es) Composiciones de tigeciclina y métodos de preparación
CL2007002856A1 (es) Compuestos derivados de pirazolo(1,5)pirimidina; composicion farmaceutica qu lo comprende;y su uso para tratar el cancer.
ECSP088905A (es) Nuevos compuestos
GT200900204A (es) Compuestos complejos de hidrato de carbono y hierro
CR8559A (es) Pirazolopirimidinas
CL2007002388A1 (es) Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento de hemangiomas o hemangioblastomas.
CR9645A (es) Complejos con contenido de perfluoroalquilo, procedimientos para su preparacion asi como su uso
AR058127A1 (es) Derivados de piperidina antagonistas de cgrp, procedimientos para su preparacion asi como su uso como medicamentos
UY31700A (es) Tiazolil-dihidro-indazoles