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GT200500219A - 4-(2,4-dicloro-5-metoxifenil)amino-6-metoxi-7([5-amino-sustituido)metil]-3-furil)-3-quinolincarbonitrilos comoinhibidores de quinasa. - Google Patents

4-(2,4-dicloro-5-metoxifenil)amino-6-metoxi-7([5-amino-sustituido)metil]-3-furil)-3-quinolincarbonitrilos comoinhibidores de quinasa.

Info

Publication number
GT200500219A
GT200500219A GT200500219A GT200500219A GT200500219A GT 200500219 A GT200500219 A GT 200500219A GT 200500219 A GT200500219 A GT 200500219A GT 200500219 A GT200500219 A GT 200500219A GT 200500219 A GT200500219 A GT 200500219A
Authority
GT
Guatemala
Prior art keywords
amino
quinolincarbonitrilos
metoxifenil
metoxi
dicloro
Prior art date
Application number
GT200500219A
Other languages
English (en)
Inventor
Diane Harris Boschelli
Asaf Alimardanov
Biqi Wu
Jay Thomas Afragola
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200500219A publication Critical patent/GT200500219A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCIÓN SE RELACIONA CON COMPUESTOS QUE TIENEN LA ESTRUCTURA DE FÓRMULA I, QUE INHIBEN LA ACTIVIDAD DE LAS QUINASAS, DICHO COMPUESTOS SON ÚTILES PARA EL TRATAMIENTO DEL CANCER.
GT200500219A 2004-08-16 2005-08-12 4-(2,4-dicloro-5-metoxifenil)amino-6-metoxi-7([5-amino-sustituido)metil]-3-furil)-3-quinolincarbonitrilos comoinhibidores de quinasa. GT200500219A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60182504P 2004-08-16 2004-08-16

Publications (1)

Publication Number Publication Date
GT200500219A true GT200500219A (es) 2006-03-07

Family

ID=35395715

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200500219A GT200500219A (es) 2004-08-16 2005-08-12 4-(2,4-dicloro-5-metoxifenil)amino-6-metoxi-7([5-amino-sustituido)metil]-3-furil)-3-quinolincarbonitrilos comoinhibidores de quinasa.

Country Status (6)

Country Link
US (1) US7479561B2 (es)
AR (1) AR053409A1 (es)
GT (1) GT200500219A (es)
PE (1) PE20060495A1 (es)
TW (1) TW200612944A (es)
WO (1) WO2006023395A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
WO2008064004A2 (en) * 2006-11-16 2008-05-29 Wyeth 4-anilino-3-quinolinecarbonitriles for the treatment of acute myelogenous leukemia (aml)
US20080119463A1 (en) * 2006-11-16 2008-05-22 Wyeth 4-Anilino-3-quinolinecarbonitriles for the treatment of acute myelogenous leukemia (AML)
JP6280546B2 (ja) 2012-06-26 2018-02-14 デル マー ファーマシューティカルズ ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
WO2014086284A1 (zh) * 2012-12-04 2014-06-12 上海医药集团股份有限公司 一类氘代3-氰基喹啉类化合物、其药用组合物、制备方法及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
AR035851A1 (es) * 2000-03-28 2004-07-21 Wyeth Corp 3-cianoquinolinas, 3-ciano-1,6-naftiridinas y 3-ciano-1,7-naftiridinas como inhibidoras de proteina quinasas
US6961765B2 (en) * 2000-04-06 2005-11-01 Bbx Technologies, Inc. System and method for real time monitoring and control of networked computers
EP1660453A2 (en) 2003-08-19 2006-05-31 Wyeth Holdings Corporation Process for the preparation of 4-amino-3-quinolinecarbonitriles

Also Published As

Publication number Publication date
US20060035930A1 (en) 2006-02-16
AR053409A1 (es) 2007-05-09
PE20060495A1 (es) 2006-07-14
WO2006023395A2 (en) 2006-03-02
US7479561B2 (en) 2009-01-20
TW200612944A (en) 2006-05-01
WO2006023395A3 (en) 2006-06-08

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