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GR3030263T3 - Delta 16 unsaturated c 17 heterocyclic steroids useful as steroid c 17-20 lyase inhibitors - Google Patents

Delta 16 unsaturated c 17 heterocyclic steroids useful as steroid c 17-20 lyase inhibitors

Info

Publication number
GR3030263T3
GR3030263T3 GR990401356T GR990401356T GR3030263T3 GR 3030263 T3 GR3030263 T3 GR 3030263T3 GR 990401356 T GR990401356 T GR 990401356T GR 990401356 T GR990401356 T GR 990401356T GR 3030263 T3 GR3030263 T3 GR 3030263T3
Authority
GR
Greece
Prior art keywords
steroid
delta
unsaturated
lyase inhibitors
steroids useful
Prior art date
Application number
GR990401356T
Other languages
English (en)
Inventor
Norton P Peet
Joseph P Burkhart
Cynthia P Gates
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of GR3030263T3 publication Critical patent/GR3030263T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR990401356T 1993-10-27 1999-05-19 Delta 16 unsaturated c 17 heterocyclic steroids useful as steroid c 17-20 lyase inhibitors GR3030263T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14367993A 1993-10-27 1993-10-27
PCT/US1994/011030 WO1995011914A1 (en) 1993-10-27 1994-09-29 Δ16 unsaturated c¿17? heterocyclic steroids useful as steroid c17-20 lyase inhibitors

Publications (1)

Publication Number Publication Date
GR3030263T3 true GR3030263T3 (en) 1999-08-31

Family

ID=22505119

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990401356T GR3030263T3 (en) 1993-10-27 1999-05-19 Delta 16 unsaturated c 17 heterocyclic steroids useful as steroid c 17-20 lyase inhibitors

Country Status (19)

Country Link
US (3) US5677293A (el)
EP (1) EP0724591B1 (el)
JP (1) JPH09511214A (el)
KR (1) KR960705838A (el)
CN (1) CN1046736C (el)
AT (1) ATE177751T1 (el)
AU (2) AU684844B2 (el)
CA (1) CA2173729C (el)
DE (1) DE69417248T2 (el)
DK (1) DK0724591T3 (el)
ES (1) ES2133582T3 (el)
FI (1) FI961792A0 (el)
GR (1) GR3030263T3 (el)
HU (1) HUT73855A (el)
IL (1) IL111364A0 (el)
NO (1) NO961693L (el)
NZ (1) NZ274694A (el)
WO (1) WO1995011914A1 (el)
ZA (1) ZA948310B (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
WO2001005364A1 (en) * 1999-07-15 2001-01-25 The Procter & Gamble Company Nitrogen-containing steroid compounds and their use to regulate hair growth
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US6562457B1 (en) 2001-10-31 2003-05-13 E. I. Du Pont De Nemours And Company Polyether ester elastomer comprising polytrimethylene ether ester soft segment and tetramethylene ester hard segment
US8569275B2 (en) 2002-08-28 2013-10-29 Harbor Therapeutics, Inc. Steroids having 7-oxgen and 17-heteroaryl substitution
CN101287411B (zh) 2005-04-28 2013-03-06 普罗秋斯生物医学公司 药物信息系统及其用途
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20110178065A1 (en) * 2010-01-15 2011-07-21 Biomarin Pharmaceutical Inc. Novel cyp17 inhibitors
CN103124563B (zh) 2010-08-04 2016-08-10 佩尔菲丘尔制药有限公司 用于前列腺癌治疗的联合治疗
CN102746358B (zh) * 2011-04-22 2016-02-10 天津金耀集团有限公司 一种合成孕甾21位溴化物的工艺
CN102898495B (zh) * 2012-11-12 2014-11-26 浙江神洲药业有限公司 醋酸阿比特龙酯的制备方法
CN103059091B (zh) * 2012-11-22 2017-04-19 常州靶点医药科技有限公司 一种避免重金属残留的醋酸阿比特龙的制备方法
EP2968219B1 (en) 2013-03-14 2019-04-24 Pellficure Pharmaceuticals, Inc. Novel therapy for prostate carcinoma
US10093620B2 (en) 2014-09-12 2018-10-09 Pellficure Pharmaceuticals, Inc. Compositions and methods for treatment of prostate carcinoma
HUP1500055A1 (hu) 2015-02-09 2016-08-29 Druggability Technologies Ip Holdco Ltd Abirateron acetát komplexei, eljárás elõállításukra, és az azokat tartalmazó gyógyászati készítmények
CA3044812A1 (en) 2016-10-24 2018-05-03 Pellficure Pharmaceuticals Inc. Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1,4-dione
CN106866773A (zh) * 2017-02-14 2017-06-20 西北农林科技大学 一组具有抗癌活性吡唑基甾体衍生物的制备方法及应用
CN116621905B (zh) * 2023-06-06 2025-07-15 西北农林科技大学 双烯噻唑类衍生物及其合成方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1081647A (en) * 1965-04-01 1967-08-31 Shionogi & Co Furan compounds
AT253975B (de) * 1965-06-15 1967-05-10 Carinthia Elektrogeraete Ges M Trockenrasierapparat
US3398138A (en) * 1966-05-24 1968-08-20 American Home Prod Novel cardenolides and derivatives
US3436390A (en) * 1966-05-24 1969-04-01 American Home Prod 4,4-dihydroxy-2-butenoic acid lactones
US4259240A (en) * 1979-09-28 1981-03-31 Advance Biofactures Corporation Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom
US4380624A (en) * 1981-07-31 1983-04-19 Advance Biofactures Corp. Novel isomers of bufalin and resibufogenin and their preparation
US4523917A (en) * 1983-12-27 1985-06-18 Dana Corporation Variable pitch diameter torque sensing pulley assembly
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
ATE186913T1 (de) * 1992-03-31 1999-12-15 Btg Int Ltd 17-substituierte steroide, verwendbar bei behandlung von krebs
DE4221636C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate

Also Published As

Publication number Publication date
US5677293A (en) 1997-10-14
US5965548A (en) 1999-10-12
FI961792L (fi) 1996-04-26
NZ274694A (en) 1998-01-26
CN1133596A (zh) 1996-10-16
FI961792A7 (fi) 1996-04-26
NO961693D0 (no) 1996-04-26
WO1995011914A1 (en) 1995-05-04
FI961792A0 (fi) 1996-04-26
NO961693L (no) 1996-04-26
DK0724591T3 (da) 1999-09-27
CA2173729C (en) 2001-05-15
CN1046736C (zh) 1999-11-24
DE69417248T2 (de) 1999-08-19
EP0724591B1 (en) 1999-03-17
CA2173729A1 (en) 1995-05-04
IL111364A0 (en) 1994-12-29
ZA948310B (en) 1995-06-14
HUT73855A (en) 1996-09-30
KR960705838A (ko) 1996-11-08
EP0724591A1 (en) 1996-08-07
AU695341B2 (en) 1998-08-13
US5977094A (en) 1999-11-02
JPH09511214A (ja) 1997-11-11
AU684844B2 (en) 1998-01-08
AU7922394A (en) 1995-05-22
ES2133582T3 (es) 1999-09-16
AU3993097A (en) 1998-01-08
DE69417248D1 (de) 1999-04-22
HU9601113D0 (en) 1996-07-29
ATE177751T1 (de) 1999-04-15

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