GR3019058T3 - 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions - Google Patents

3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions

Info

Publication number: GR3019058T3
Authority: GR; Greece
Prior art keywords: arylcarbonyl; aminoalkyl; indole containing; antiglaucoma compositions; antiglaucoma
Prior art date: 1990-03-08

Application number

GR950402831T

Other languages

English (en)

Inventor

Susan Jean Ward

Malcolm Rice Bell

Original Assignee

Sterling Winthrop Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-08

Filing date

1996-02-22

Publication date

1996-05-31

1996-02-22 Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc

1996-05-31 Publication of GR3019058T3 publication Critical patent/GR3019058T3/el

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Ophthalmology & Optometry (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cosmetics (AREA)

GR950402831T 1990-03-08 1996-02-22 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions GR3019058T3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US49020190A	1990-03-08	1990-03-08

Publications (1)

Publication Number	Publication Date
GR3019058T3 true GR3019058T3 (en)	1996-05-31

Family

ID=23947024

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR950402831T GR3019058T3 (en)	1990-03-08	1996-02-22	3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions

Country Status (21)

Country	Link
EP (1)	EP0445781B1 (el)
JP (1)	JP3157179B2 (el)
KR (1)	KR0183396B1 (el)
AT (1)	ATE133663T1 (el)
AU (1)	AU643757B2 (el)
CA (1)	CA2036307C (el)
DE (1)	DE69116705T2 (el)
DK (1)	DK0445781T3 (el)
ES (1)	ES2082872T3 (el)
FI (1)	FI95369C (el)
GR (1)	GR3019058T3 (el)
HU (1)	HU215125B (el)
IE (1)	IE72953B1 (el)
IL (1)	IL97426A (el)
MX (1)	MX174433B (el)
MY (1)	MY106109A (el)
NO (1)	NO179612C (el)
NZ (1)	NZ237309A (el)
PH (1)	PH27022A (el)
PT (1)	PT96938B (el)
RU (1)	RU2073670C1 (el)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5068234A (en) *	1990-02-26	1991-11-26	Sterling Drug Inc.	3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
GB9204365D0 (en) *	1992-02-28	1992-04-08	Pfizer Ltd	Indoles
FR2713225B1 (fr) *	1993-12-02	1996-03-01	Sanofi Sa	N-pipéridino-3-pyrazolecarboxamide substitué.
FR2713224B1 (fr) *	1993-12-02	1996-03-01	Sanofi Sa	N-pipéridino-3-pyrazolecarboxamide substitué.
FR2692575B1 (fr) *	1992-06-23	1995-06-30	Sanofi Elf	Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
ES2099007B1 (es) *	1993-07-16	1997-12-01	Pfizer Res & Dev	Derivados de indol.
FR2714057B1 (fr) *	1993-12-17	1996-03-08	Sanofi Elf	Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
ID27812A (id) *	1998-05-01	2001-04-26	Lilly Co Eli	ESTER PENGHAMBAT sPLA2
ES2204067T3 (es) *	1998-05-26	2004-04-16	Pfizer Products Inc.	Medicamento para el tratamiento del glaucoma y de la retinopatia isquemica.
WO2001040183A1 (en) *	1999-12-03	2001-06-07	Alcon Universal Ltd.	1-aminoalkyl-1h-indoles for treating glaucoma
AU771130B2 (en) *	2000-01-18	2004-03-11	Merck & Co., Inc.	Ophthalmic compositions for treating ocular hypertension
WO2001058869A2 (en) *	2000-02-11	2001-08-16	Bristol-Myers Squibb Company	Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
TWI231757B (en) *	2001-09-21	2005-05-01	Solvay Pharm Bv	1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
AR038966A1 (es) *	2002-03-18	2005-02-02	Solvay Pharm Bv	Derivados de tiazol que tienen actividad antagonista, agonista o agonista parcial de cb1
SE0203070D0 (en) *	2002-10-16	2002-10-16	Astrazeneca Ab	Novel compounds
TW200508197A (en) *	2003-03-31	2005-03-01	Ucb Sa	Indolone-acetamide derivatives, processes for preparing them and their uses
RU2376302C2 (ru) *	2004-03-05	2009-12-20	Н.В.Органон	Производные (индол-3-ил)гетероциклических соединений в качестве агонистов каннабиноидных рецепторов св1
US7807707B2 (en) *	2005-03-12	2010-10-05	Conopco Inc.	Hair and/or scalp care compositions incorporating amino-oxo-indole-ylidene compounds
FR2893615B1 (fr) *	2005-11-18	2008-03-07	Sanofi Aventis Sa	Derives de 3-acylindole, leur preparation et leur application en therapeutique
RU2404185C1 (ru) *	2009-04-16	2010-11-20	Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН)	РАВНОМЕРНО МЕЧЕННЫЙ ТРИТИЕМ (R)-(+)-[5-МЕТИЛ-3-(4-МОРФОЛИНИЛМЕТИЛ)-2,3-ДИГИДРО-[1,4]ОКСАЗИНО [2,3,4-hi]-6-ИНДОЛИЛ]-1-НАФТАЛИНИЛМЕТАНОН АЦЕТАТ
JP6025234B1 (ja) *	2016-03-10	2016-11-16	株式会社サンライフ	箸における箸置き形成方法及び箸置き機能を有する箸
CN107628981B (zh) *	2017-10-31	2019-07-30	威海市妇女儿童医院	一种肉桂酰基吲哚啉化合物及其制备青光眼药物的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1436771A (en) *	1973-02-16	1976-05-26	Labaz	Indole derivatives and process for preparing the same
US4581354A (en) *	1984-08-06	1986-04-08	Sterling Drug Inc.	3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
US4634776A (en) *	1984-08-06	1987-01-06	Sterling Drug, Inc.	3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles
US4634698A (en) *	1984-09-24	1987-01-06	Schering Corporation	Antiglaucoma agents
DE3821148A1 (de) *	1988-06-23	1989-12-28	Erwin Von Dr Angerer	Aminoalkylindole, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate

1991
- 1991-02-13 CA CA002036307A patent/CA2036307C/en not_active Expired - Lifetime
- 1991-03-01 IE IE70091A patent/IE72953B1/en not_active IP Right Cessation
- 1991-03-04 PH PH42084A patent/PH27022A/en unknown
- 1991-03-04 IL IL9742691A patent/IL97426A/en not_active IP Right Cessation
- 1991-03-05 HU HU91711A patent/HU215125B/hu unknown
- 1991-03-05 PT PT96938A patent/PT96938B/pt not_active IP Right Cessation
- 1991-03-05 NO NO910868A patent/NO179612C/no not_active IP Right Cessation
- 1991-03-05 NZ NZ237309A patent/NZ237309A/xx unknown
- 1991-03-06 DK DK91103425.4T patent/DK0445781T3/da active
- 1991-03-06 ES ES91103425T patent/ES2082872T3/es not_active Expired - Lifetime
- 1991-03-06 FI FI911131A patent/FI95369C/fi active
- 1991-03-06 EP EP91103425A patent/EP0445781B1/en not_active Expired - Lifetime
- 1991-03-06 DE DE69116705T patent/DE69116705T2/de not_active Expired - Lifetime
- 1991-03-06 AT AT91103425T patent/ATE133663T1/de not_active IP Right Cessation
- 1991-03-06 AU AU72669/91A patent/AU643757B2/en not_active Expired
- 1991-03-07 MY MYPI91000354A patent/MY106109A/en unknown
- 1991-03-07 KR KR1019910003817A patent/KR0183396B1/ko not_active Expired - Lifetime
- 1991-03-08 MX MX024839A patent/MX174433B/es unknown
- 1991-03-08 JP JP04383191A patent/JP3157179B2/ja not_active Expired - Lifetime
1992
- 1992-05-27 RU SU925011872A patent/RU2073670C1/ru active
1996
- 1996-02-22 GR GR950402831T patent/GR3019058T3/el unknown

Also Published As

Publication number	Publication date
HUT56492A (en)	1991-09-30
CA2036307C (en)	2002-07-09
DE69116705D1 (de)	1996-03-14
RU2073670C1 (ru)	1997-02-20
EP0445781A1 (en)	1991-09-11
EP0445781B1 (en)	1996-01-31
FI911131A0 (fi)	1991-03-06
JPH04235164A (ja)	1992-08-24
JP3157179B2 (ja)	2001-04-16
FI95369B (fi)	1995-10-13
NZ237309A (en)	1993-02-25
PT96938A (pt)	1991-10-31
NO910868L (no)	1991-09-09
DE69116705T2 (de)	1996-09-26
IE910700A1 (en)	1991-09-11
HU215125B (hu)	1998-09-28
KR910016745A (ko)	1991-11-05
PH27022A (en)	1993-02-01
FI911131L (fi)	1991-09-09
ES2082872T3 (es)	1996-04-01
AU643757B2 (en)	1993-11-25
CA2036307A1 (en)	1991-09-09
DK0445781T3 (da)	1996-02-19
MY106109A (en)	1995-03-31
MX174433B (es)	1994-05-16
MX24839A (es)	1993-10-01
AU7266991A (en)	1991-09-12
IL97426A (en)	1996-03-31
FI95369C (fi)	1996-01-25
IL97426A0 (en)	1992-06-21
ATE133663T1 (de)	1996-02-15
NO910868D0 (no)	1991-03-05
KR0183396B1 (ko)	1999-05-01
NO179612B (no)	1996-08-05
NO179612C (no)	1996-11-13
PT96938B (pt)	1998-07-31
IE72953B1 (en)	1997-05-07

Publication	Publication Date	Title
IL97426A0 (en)	1992-06-21	3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions
ZA907338B (en)	1992-08-26	Thienylcarboxylates of amino alcohols
DK0472327T3 (da)	1995-05-08	Præparat på form af øjendråber
EP0250088A3 (en)	1990-03-28	Use of tetrahydrocortisol in glaucoma therapy
HUT60318A (en)	1992-08-28	Compositions comprising isothiazolone derivative stabilized with phenoxyalkanol and process for producing and applying them
HUT49793A (en)	1989-11-28	Herbicide compositions containing n-aryl-tetrahydro-phtalimides as active components and process for producing the active components
AU1146083A (en)	1983-09-08	2,3-diaryl-5-halo thiophenes
ATE117208T1 (de)	1995-02-15	Behandlung von intraokularem druck mit einer ophthalmischen synergistischen kombination.
ATE109465T1 (de)	1994-08-15	4-aryl-4-piperidine (oder -pyrrolidin- oder - hexahydroazepin-) carbinole und heterocyclische analoga davon.
FR2483234B2 (el)	1983-12-23
EP0254239A3 (en)	1988-10-26	Optically pure 1,3-dioxenones, methods for preparing same and use thereof
JPS6450886A (en)	1989-02-27	Substituted thieno(2,3-b)thiophene-2-sulfonamides as antiglaucoma
HUT52763A (en)	1990-08-28	Herbicide and growth-controlling compositions containing sulfonyl-urea derivatives as active components and process for producing the active components
EP0401262A4 (en)	1993-05-05	24r-scymnol, and preparation and use thereof
ZA913920B (en)	1992-02-26	Therapeutic compound
HUT44132A (en)	1988-02-29	Herbicide compositions containing pyrazolo-(-3,4-b-)-pyridine derivatives as active components and process for producing the active components
HUT52485A (en)	1990-07-28	Herbicide compositions containing benzo(f)indazol-4,9-quinones as active components and process for producing the active components
HUT56069A (en)	1991-07-29	Fungicide composition sontaining pyridyl-cyclopropane-amines as active components and process for producing the active components
AU623386B2 (en)	1992-05-14	1-dimethylcarbamoyl-3-substituted-5-substituted-1h-1,2,4- triazoles
ZA874878B (en)	1989-03-29	Pyran derivatives
AU627874B2 (en)	1992-09-03	Amino-benzenesulfonamides in the treatment of glaucoma
SG13094G (en)	1994-06-10	Stabilization of the preservative thiomersal in ophthalmic pharmaceutical compositions.